Motif ID: TEAD1.p2

Z-value: 1.639


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD4chr12_+_3068442-0.792.0e-02Click!
TEAD2chr19_-_49865638-0.611.1e-01Click!
TEAD1chr11_+_126958510.245.6e-01Click!
TEAD3chr6_-_354647160.235.9e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132272311 2.080 NM_001901
CTGF
connective tissue growth factor
chr5_-_39424930 1.823 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr19_+_34972866 1.588 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr8_-_108510094 1.549 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_-_1293907 1.518 NM_032348
MXRA8
matrix-remodelling associated 8
chr15_-_48937795 1.376 NM_000138
FBN1
fibrillin 1
chr12_-_47219734 1.303 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr20_+_35169876 1.292 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr3_-_112359547 1.272 CCDC80
coiled-coil domain containing 80
chr1_-_92351476 1.261 TGFBR3
transforming growth factor, beta receptor III
chr20_+_35169897 1.231 MYL9
myosin, light chain 9, regulatory
chr3_-_112359863 1.200 CCDC80
coiled-coil domain containing 80
chr19_+_36359346 1.199 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr3_-_112359660 1.178 CCDC80
coiled-coil domain containing 80
chr3_-_112359962 1.169 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr3_-_112359277 1.158 CCDC80
coiled-coil domain containing 80
chr3_-_112359565 1.144 CCDC80
coiled-coil domain containing 80
chr3_-_112359443 1.124 CCDC80
coiled-coil domain containing 80
chr3_-_112359251 1.105 CCDC80
coiled-coil domain containing 80
chr1_+_114522029 1.091 NM_020190
OLFML3
olfactomedin-like 3
chr1_-_3447974 1.084 MEGF6
multiple EGF-like-domains 6
chr5_-_39425030 1.067 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_19988293 1.049 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr19_+_45409003 1.037 NM_000041
APOE
apolipoprotein E
chr8_-_12973752 1.028 NM_001164271
DLC1
deleted in liver cancer 1
chr3_-_9994057 1.002 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr12_-_63328663 0.995 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_-_186733372 0.993 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr16_+_29823557 0.942 PRRT2
proline-rich transmembrane protein 2
chr3_-_114343052 0.936 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_96184510 0.925 NM_021229
NTN4
netrin 4
chr16_+_29823408 0.920 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr2_+_152214105 0.913 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_131630065 0.891 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr14_+_76044939 0.886 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr2_-_190044330 0.885 NM_000393
COL5A2
collagen, type V, alpha 2
chr8_+_70378858 0.879 NM_001128204
NM_015170
SULF1

sulfatase 1

chr1_-_92351613 0.842 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr10_-_21186530 0.820 NM_006393
NEBL
nebulette
chr5_-_39425297 0.785 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr10_-_44063906 0.761 NM_005674
ZNF239
zinc finger protein 239
chr1_+_164528586 0.740 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr12_-_56101465 0.733 ITGA7
integrin, alpha 7
chr15_+_63335086 0.707 TPM1
tropomyosin 1 (alpha)
chr21_+_47545189 0.706 COL6A2
collagen, type VI, alpha 2
chr4_-_186578122 0.701 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr17_-_45899118 0.683 OSBPL7
oxysterol binding protein-like 7
chr12_-_7245048 0.665 C1R
complement component 1, r subcomponent
chr12_-_7245006 0.659 NM_001733
C1R
complement component 1, r subcomponent
chr16_+_30907927 0.651 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chr19_-_44831907 0.641 ZFP112
zinc finger protein 112 homolog (mouse)
chr3_-_119379269 0.626 NM_022135
POPDC2
popeye domain containing 2
chr4_-_57547845 0.610 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr12_-_56101667 0.606 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr17_-_45899133 0.604 NM_145798
OSBPL7
oxysterol binding protein-like 7
chr1_+_78354199 0.603 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr16_+_33261514 0.596 NM_016212
TP53TG3
TP53 target 3
chr12_+_53442732 0.594 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr4_-_89618928 0.588 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr15_+_63334753 0.588 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr11_+_2924504 0.585 SLC22A18
solute carrier family 22, member 18
chr12_+_79258517 0.557 SYT1
synaptotagmin I
chr16_+_15528324 0.543 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr6_+_132891460 0.543 NM_175067
TAAR6
trace amine associated receptor 6
chr10_-_90712510 0.537 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_+_102759184 0.524 IL1R1
interleukin 1 receptor, type I
chr12_+_79258588 0.502 SYT1
synaptotagmin I
chr6_-_128841432 0.501 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr5_-_151066492 0.480 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_+_91087601 0.477 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr9_+_118916069 0.475 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr16_-_122573 0.467 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr19_+_44645728 0.456 ZNF234
zinc finger protein 234
chr12_+_79258448 0.453 NM_005639
SYT1
synaptotagmin I
chr6_+_155411422 0.450 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr12_-_63328857 0.448 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr5_-_180688095 0.441 NM_032765
TRIM52
tripartite motif containing 52
chrX_-_83757398 0.439 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr7_+_134464372 0.437 CALD1
caldesmon 1
chr1_-_58716207 0.435 NM_021080
DAB1
disabled homolog 1 (Drosophila)
chr1_+_104159953 0.427 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr1_-_151431648 0.416 POGZ
pogo transposable element with ZNF domain
chrX_+_53111482 0.414 NM_022117
TSPYL2
TSPY-like 2
chr6_+_134210264 0.412 TCF21
transcription factor 21
chr7_-_137686812 0.412 CREB3L2
cAMP responsive element binding protein 3-like 2
chr1_+_163038564 0.408 NM_005613
RGS4
regulator of G-protein signaling 4
chr11_-_6341708 0.406 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr8_-_103666018 0.405 NM_001032282
KLF10
Kruppel-like factor 10
chrX_-_142722869 0.405 NM_173078
SLITRK4
SLIT and NTRK-like family, member 4
chr11_+_71639767 0.397 NM_018320
RNF121
ring finger protein 121
chr5_-_55290601 0.396 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr19_-_14048877 0.392 PODNL1
podocan-like 1
chr17_-_39093671 0.391 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_79257772 0.382 NM_001135805
SYT1
synaptotagmin I
chr19_-_14049167 0.380 NM_024825
PODNL1
podocan-like 1
chr20_+_30946786 0.376 ASXL1
additional sex combs like 1 (Drosophila)
chr1_+_53925071 0.368 NM_033067
DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr4_+_148538564 0.367 TMEM184C
transmembrane protein 184C
chr16_-_31076408 0.362 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr10_-_7682741 0.360 ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr15_+_33010174 0.357 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr17_-_4693595 0.357 LOC284014
uncharacterized LOC284014
chr15_-_49338496 0.355 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr19_+_50936159 0.355 NM_004533
MYBPC2
myosin binding protein C, fast type
chr18_+_3247825 0.354 MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_-_63557764 0.354 AXIN2
axin 2
chr2_-_20212408 0.353 MATN3
matrilin 3
chr5_-_177423242 0.349 NM_006261
PROP1
PROP paired-like homeobox 1
chr7_-_137686778 0.343 CREB3L2
cAMP responsive element binding protein 3-like 2
chr9_-_73483933 0.339 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr1_+_163038934 0.339 NM_001113381
RGS4
regulator of G-protein signaling 4
chr11_+_5410606 0.335 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr19_-_9649257 0.334 NM_024106
ZNF426
zinc finger protein 426
chr19_-_13617037 0.331 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr6_+_108881010 0.330 NM_201559
FOXO3
forkhead box O3
chr11_+_196760 0.322 NM_053280
ODF3
outer dense fiber of sperm tails 3
chr5_-_151066445 0.321 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_-_214724974 0.321 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr16_+_47495225 0.320 PHKB
phosphorylase kinase, beta
chr6_-_167571315 0.317 NM_005299
GPR31
G protein-coupled receptor 31
chr19_-_51472003 0.316 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr16_+_222845 0.310 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr3_-_46904879 0.310 NM_000258
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr5_+_180688174 0.309


chr4_+_148538508 0.307 NM_018241
TMEM184C
transmembrane protein 184C
chr11_-_2170792 0.306 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_-_116681253 0.304 TRPS1
trichorhinophalangeal syndrome I
chrX_+_107683015 0.304 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr17_-_63557615 0.302 NM_004655
AXIN2
axin 2
chr17_+_78194090 0.302 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chrX_+_86772714 0.302 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr8_-_95220769 0.299 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_-_48278987 0.298 NM_000088
COL1A1
collagen, type I, alpha 1
chr5_-_38595506 0.297 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr9_-_95166827 0.296 NM_014057
NM_033014
OGN

osteoglycin

chr1_+_226016428 0.294 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr6_+_31802644 0.291 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr7_-_150946031 0.289 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr16_+_47495166 0.285 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta

chr22_+_24577443 0.285 NM_019601
SUSD2
sushi domain containing 2
chr16_+_1032063 0.284 SOX8
SRY (sex determining region Y)-box 8
chr2_-_158731622 0.275 NM_001105
ACVR1
activin A receptor, type I
chr6_+_52929795 0.275 NM_033481
FBXO9
F-box protein 9
chr6_+_84222252 0.273 PRSS35
protease, serine, 35
chr11_+_48002063 0.272 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr19_+_14491920 0.270 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr16_+_226678 0.270 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr5_-_95158365 0.269 GLRX
glutaredoxin (thioltransferase)
chr11_+_48002120 0.268 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr19_+_12075868 0.268 NM_001012753
ZNF763
zinc finger protein 763
chr2_-_20212448 0.265 NM_002381
MATN3
matrilin 3
chr3_+_38347426 0.264 NM_004803
SLC22A14
solute carrier family 22, member 14
chr7_+_8008416 0.263 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr9_+_137533713 0.263 COL5A1
collagen, type V, alpha 1
chr1_-_17307107 0.262 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr8_-_38325241 0.261 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chrX_+_79675945 0.259 NM_152630
FAM46D
family with sequence similarity 46, member D
chr12_-_122240827 0.258


chr2_+_112895958 0.258 NM_001128165
NM_153214
FBLN7

fibulin 7

chr14_-_89020888 0.256 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr7_-_137686814 0.256 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr1_-_198510074 0.255 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr5_-_43412417 0.253 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr5_+_140749830 0.251 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr17_-_48278874 0.250 COL1A1
collagen, type I, alpha 1
chr8_+_1772095 0.249 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr6_+_52930160 0.245 FBXO9
F-box protein 9
chr16_-_47495095 0.244 ITFG1
integrin alpha FG-GAP repeat containing 1
chr19_+_11998609 0.239 NM_021915
ZNF69
zinc finger protein 69
chr16_+_28889808 0.239 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr6_-_75915753 0.235 COL12A1
collagen, type XII, alpha 1
chr5_+_140868721 0.235 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr14_-_77494621 0.235 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr15_-_69707358 0.235 LOC145694
uncharacterized LOC145694
chr14_+_21467413 0.234 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr9_+_34990715 0.234 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr22_-_36635999 0.232 NM_145637
APOL2
apolipoprotein L, 2
chr3_+_9944511 0.232 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr6_-_83903632 0.230 NM_001199917
PGM3
phosphoglucomutase 3
chr6_-_31681845 0.229


chr1_+_51435911 0.229 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_-_6643809 0.228 DCHS1
dachsous 1 (Drosophila)
chr2_-_96482382 0.225 LINC00342
long intergenic non-protein coding RNA 342
chr8_+_145086444 0.225 NM_001134374
NM_198572
SPATC1

spermatogenesis and centriole associated 1

chr1_+_218518675 0.224 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr9_-_130533509 0.224 NM_001252334
NM_005489
SH2D3C

SH2 domain containing 3C

chr1_-_162381805 0.223 NM_053282
SH2D1B
SH2 domain containing 1B
chr16_+_33204979 0.223 NM_016212
TP53TG3
TP53 target 3
chr1_-_120935893 0.223 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr3_-_149086884 0.223 TM4SF1
transmembrane 4 L six family member 1
chr3_-_127541160 0.222 NM_007283
MGLL
monoglyceride lipase
chr6_+_52930222 0.220 NM_033480
FBXO9
F-box protein 9
chr5_-_150138081 0.217 NM_001135644
DCTN4
dynactin 4 (p62)
chr5_-_95158465 0.214 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr2_-_217540722 0.213 IGFBP5
insulin-like growth factor binding protein 5
chr14_-_35591151 0.209 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr6_+_83903031 0.208 NM_033411
RWDD2A
RWD domain containing 2A
chr11_+_22689653 0.207 NM_177553
GAS2
growth arrest-specific 2
chr6_+_52930217 0.206 FBXO9
F-box protein 9
chr19_-_49371710 0.206 NM_001161354
NM_020904
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.10 3.01e-04 GO:0030198 extracellular matrix organization
1.45 3.93e-03 GO:0042221 response to chemical stimulus
3.86 6.64e-03 GO:0050730 regulation of peptidyl-tyrosine phosphorylation
2.96 1.82e-02 GO:0043062 extracellular structure organization
4.12 2.68e-02 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 6.06e-07 GO:0005576 extracellular region
2.47 9.60e-06 GO:0031012 extracellular matrix
2.58 1.77e-05 GO:0005578 proteinaceous extracellular matrix
3.77 4.28e-05 GO:0044420 extracellular matrix part
1.76 9.29e-05 GO:0044421 extracellular region part
4.35 3.99e-04 GO:0005604 basement membrane
16.89 5.19e-04 GO:0005587 collagen type IV
14.48 1.74e-03 GO:0030935 sheet-forming collagen
5.07 1.47e-02 GO:0005581 collagen

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.06 4.96e-04 GO:0001871 pattern binding
3.06 4.96e-04 GO:0030247 polysaccharide binding
1.91 7.94e-04 GO:0005509 calcium ion binding
3.04 1.60e-03 GO:0005539 glycosaminoglycan binding
5.19 2.65e-03 GO:0008307 structural constituent of muscle
3.29 3.95e-03 GO:0008201 heparin binding