Motif ID: TFEB.p2

Z-value: 1.711


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41702734,
chr6_-_41703938		0.902.5e-03Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_35777087 3.310 HMOX1
heme oxygenase (decycling) 1
chr1_+_183605207 3.225 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr17_-_66951381 2.966 NM_007168
 ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr19_+_49458151 2.935 BAX
BCL2-associated X protein
chr19_+_49458031 2.870 NM_004324
NM_138761
NM_138763
NM_138764
 BAX



BCL2-associated X protein



chr19_+_49458129 2.842 BAX
BCL2-associated X protein
chr11_+_67776016 2.689 NM_001161473
 ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chrX_+_55744049 2.629 NM_006064
NM_016656
 RRAGB

Ras-related GTP binding B

chr10_-_93392857 2.423 NM_005398
 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr19_-_36545119 2.362 THAP8
THAP domain containing 8
chr12_+_56109832 2.270 BLOC1S1-RDH5
BLOC1S1
BLOC1S1-RDH5 readthrough
biogenesis of lysosomal organelles complex-1, subunit 1
chr7_+_102074002 2.236 ORAI2
ORAI calcium release-activated calcium modulator 2
chr5_-_172198160 2.219 NM_004417
 DUSP1
dual specificity phosphatase 1
chr1_-_26232890 2.141 NM_001145454
NM_005563
 STMN1

stathmin 1

chr5_-_150537306 1.985 ANXA6
annexin A6
chr19_+_14544100 1.973 NM_002741
 PKN1
protein kinase N1
chr4_-_100242487 1.956 NM_000668
 ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr20_+_44520021 1.946 CTSA
cathepsin A
chr7_-_27196163 1.904 NM_006896
 HOXA7
homeobox A7
chr19_+_14544216 1.878 PKN1
protein kinase N1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
8.77 2.78e-03 GO:0032006 regulation of TOR signaling cascade
5.48 2.27e-03 GO:0007033 vacuole organization
4.75 4.73e-03 GO:0006818 hydrogen transport
4.54 1.91e-02 GO:0015992 proton transport
1.81 9.19e-03 GO:0033554 cellular response to stress
1.68 1.50e-02 GO:0008104 protein localization
1.59 2.19e-02 GO:0033036 macromolecule localization
1.39 1.80e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 6.70e-03 GO:0034641 cellular nitrogen compound metabolic process
1.36 6.72e-03 GO:0006807 nitrogen compound metabolic process
1.35 4.55e-02 GO:0006810 transport
1.27 1.38e-04 GO:0044237 cellular metabolic process
1.21 4.34e-03 GO:0008152 metabolic process
1.21 2.69e-02 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
7.68 6.24e-03 GO:0033176 proton-transporting V-type ATPase complex
5.10 6.09e-03 GO:0016469 proton-transporting two-sector ATPase complex
4.47 8.94e-03 GO:0031901 early endosome membrane
4.27 9.49e-09 GO:0005774 vacuolar membrane
4.22 5.93e-09 GO:0044437 vacuolar part
4.11 9.35e-03 GO:0031902 late endosome membrane
4.04 1.41e-05 GO:0005765 lysosomal membrane
3.99 4.72e-07 GO:0005769 early endosome
3.94 2.26e-05 GO:0005770 late endosome
3.70 6.69e-14 GO:0005773 vacuole
3.36 5.07e-09 GO:0000323 lytic vacuole
3.36 5.07e-09 GO:0005764 lysosome
2.75 1.12e-04 GO:0010008 endosome membrane
2.73 1.33e-04 GO:0044440 endosomal part
2.60 1.36e-07 GO:0005768 endosome
1.42 1.01e-02 GO:0031090 organelle membrane
1.35 4.99e-02 GO:0031974 membrane-enclosed lumen
1.33 5.38e-07 GO:0044446 intracellular organelle part
1.32 1.96e-07 GO:0044444 cytoplasmic part
1.32 7.36e-07 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.21 2.67e-04 GO:0005515 protein binding
1.09 3.88e-02 GO:0005488 binding