Motif ID: UGUGCUU

Z-value: 1.014


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218 MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_55095263 0.650 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr8_-_93115453 0.512 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr6_+_101846860 0.511 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr8_-_93111915 0.503 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107881 0.492 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_93029864 0.489 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107442 0.474 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr8_-_93075190 0.439 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_26348268 0.423 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr12_-_25055228 0.417 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_25055966 0.416 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_25102281 0.402 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr12_+_26348488 0.369 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr6_+_72926462 0.359 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72922513 0.337 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr6_+_73076431 0.327 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72926144 0.326 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_149889362 0.319 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr8_+_97505876 0.289 NM_002998
SDC2
syndecan 2
chr15_+_33010174 0.269 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr1_+_215256559 0.253 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr1_+_215178884 0.251 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr12_+_72666462 0.234 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr11_-_70935807 0.230 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr11_-_70507911 0.225 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_+_39892637 0.219 NM_001167959
TMEM178
transmembrane protein 178
chr2_+_39893021 0.214 NM_152390
TMEM178
transmembrane protein 178
chr8_-_81083660 0.199 NM_001025253
NM_005079
TPD52

tumor protein D52

chr5_-_158526698 0.197 NM_024007
EBF1
early B-cell factor 1
chr6_+_148663728 0.190 NM_015278
SASH1
SAM and SH3 domain containing 1
chr8_-_80993009 0.188 NM_001025252
TPD52
tumor protein D52
chr18_-_44336991 0.185 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr17_-_48278987 0.184 NM_000088
COL1A1
collagen, type I, alpha 1
chr4_-_107957452 0.169 NM_014421
DKK2
dickkopf 2 homolog (Xenopus laevis)
chr3_-_66550844 0.161 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_72596648 0.160 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_145470507 0.160 NM_001039888
ANKRD34A
ankyrin repeat domain 34A
chr12_+_79257772 0.158 NM_001135805
SYT1
synaptotagmin I
chr14_+_75898836 0.153 NM_001135049
JDP2
Jun dimerization protein 2
chr12_+_79439432 0.152 NM_001135806
SYT1
synaptotagmin I
chr2_+_121103670 0.149 NM_002193
INHBB
inhibin, beta B
chr12_+_79258448 0.146 NM_005639
SYT1
synaptotagmin I
chrX_+_16964730 0.145 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr15_-_86338178 0.144 NM_022480
KLHL25
kelch-like 25 (Drosophila)
chr18_-_25757351 0.144 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr3_+_3841079 0.142 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr14_+_75894919 0.140 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr8_-_116681103 0.136 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr5_-_176057324 0.135 NM_001001502
NM_003085
SNCB

synuclein, beta

chr9_-_93405066 0.133 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr1_+_99729847 0.133 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr10_-_62703822 0.126 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr4_-_89744154 0.126 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr6_+_118228688 0.124 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr14_+_75894508 0.124 NM_001135047
JDP2
Jun dimerization protein 2
chr14_+_92790151 0.122 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_-_11903964 0.120 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr6_+_121756744 0.120 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr11_-_134281725 0.116 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr1_-_108507474 0.116 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr14_+_92788924 0.116 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_114102488 0.115 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_114790221 0.115 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_46663207 0.114 NM_001077484
NM_030674
SLC38A1

solute carrier family 38, member 1

chr3_-_114343791 0.112 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_114478117 0.110 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr12_+_20522178 0.108 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr20_-_43438881 0.106 NM_001205317
NM_182970
RIMS4

regulating synaptic membrane exocytosis 4

chr1_-_108231122 0.106 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr3_-_79068542 0.101 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr17_-_36762105 0.101 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr14_+_92789536 0.097 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr12_-_108991893 0.096 NM_181724
TMEM119
transmembrane protein 119
chr2_+_105858199 0.096 NM_007227
GPR45
G protein-coupled receptor 45
chr3_-_114343052 0.095 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr4_+_15004297 0.095 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr15_-_27018917 0.095 NM_021912
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr11_+_120207617 0.094 NM_001198665
NM_015313
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr15_-_26961911 0.093 NM_001191320
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr7_+_44788453 0.092 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chrX_-_19817907 0.091 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr8_-_19540093 0.090 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr18_+_43914186 0.090 NM_152470
RNF165-IT1
RNF165
RNF165 intronic transcript 1 (non-protein coding)
ring finger protein 165
chr13_+_109281569 0.090 NM_001198950
MYO16
myosin XVI
chrX_-_19905665 0.086 NM_031892
SH3KBP1
SH3-domain kinase binding protein 1
chr2_-_152955208 0.086 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_+_35294771 0.085 NM_005568
LHX1
LIM homeobox 1
chr3_-_171177851 0.085 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr4_-_99579540 0.084 NM_005723
TSPAN5
tetraspanin 5
chr9_-_134151905 0.084 NM_033387
FAM78A
family with sequence similarity 78, member A
chr10_+_52834233 0.084 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr15_-_27018216 0.083 NM_000814
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr13_+_109248499 0.081 NM_015011
MYO16
myosin XVI
chr12_-_15942350 0.080 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr10_+_115803805 0.080 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr13_+_96743092 0.079 NM_153456
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr4_-_89978117 0.078 NM_014883
FAM13A
family with sequence similarity 13, member A
chr18_-_53255734 0.078 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr12_+_104697460 0.078 NM_001008394
EID3
EP300 interacting inhibitor of differentiation 3
chr12_+_78225068 0.078 NM_014903
NAV3
neuron navigator 3
chr10_+_52750904 0.077 NM_001098512
PRKG1
protein kinase, cGMP-dependent, type I
chr1_-_59165735 0.077 NM_001085487
MYSM1
Myb-like, SWIRM and MPN domains 1
chr4_+_55523906 0.076 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr2_-_152830448 0.075 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_152955502 0.075 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr7_+_44795786 0.074 NM_174929
ZMIZ2
zinc finger, MIZ-type containing 2
chr15_+_63569748 0.073 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr8_-_82024277 0.071 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr7_-_27213873 0.071 NM_018951
HOXA10
homeobox A10
chr2_+_54785453 0.070 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_-_79817058 0.070 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr15_+_74421986 0.070 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74422589 0.070 NM_001130138
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_+_49591897 0.070 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr1_-_6321034 0.069 NM_207370
GPR153
G protein-coupled receptor 153
chr17_-_41174431 0.069 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr15_+_79724857 0.068 NM_015206
KIAA1024
KIAA1024
chr15_+_74421698 0.067 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chrX_+_149861830 0.066 NM_003828
MTMR1
myotubularin related protein 1
chr4_-_185747183 0.066 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr7_-_121036355 0.066 NM_001040020
NM_014888
FAM3C

family with sequence similarity 3, member C

chrX_-_19688991 0.066 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr8_-_19460005 0.065 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_+_125486949 0.065 NM_007218
RNF139
ring finger protein 139
chr14_-_61190458 0.064 NM_017420
SIX4
SIX homeobox 4
chr15_+_74422742 0.064 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_-_73661604 0.064 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr4_+_183245136 0.064 NM_001080477
ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr14_-_52535945 0.063 NM_007361
NID2
nidogen 2 (osteonidogen)
chr6_-_105584542 0.063 NM_007073
BVES
blood vessel epicardial substance
chr1_-_119532178 0.063 NM_152380
TBX15
T-box 15
chr1_-_21978287 0.063 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr12_-_56615679 0.062 NM_005785
NM_194358
NM_194359
RNF41


ring finger protein 41


chr3_+_154798078 0.062 NM_007289
MME
membrane metallo-endopeptidase
chr3_+_154797435 0.062 NM_000902
MME
membrane metallo-endopeptidase
chr19_-_41196419 0.062 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr3_+_154797910 0.062 NM_007288
MME
membrane metallo-endopeptidase
chr1_-_21995793 0.062 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr3_+_154797644 0.062 NM_007287
MME
membrane metallo-endopeptidase
chr5_+_49961732 0.062 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_-_105584220 0.061 NM_147147
BVES
blood vessel epicardial substance
chr16_-_52581713 0.060 NM_001146188
TOX3
TOX high mobility group box family member 3
chr15_-_50411405 0.060 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr6_-_105584982 0.060 NM_001199563
BVES
blood vessel epicardial substance
chr16_-_52580805 0.059 NM_001080430
TOX3
TOX high mobility group box family member 3
chr9_-_123476578 0.059 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr3_-_14583587 0.059 NM_001080423
GRIP2
glutamate receptor interacting protein 2
chr1_+_113051369 0.059 NM_024494
WNT2B
wingless-type MMTV integration site family, member 2B
chr11_-_78052925 0.058 NM_012296
GAB2
GRB2-associated binding protein 2
chr3_+_11034419 0.058 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr17_+_1182956 0.057 NM_172367
TUSC5
tumor suppressor candidate 5
chr10_+_72575623 0.057 NM_003901
SGPL1
sphingosine-1-phosphate lyase 1
chr17_-_76356153 0.057 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr12_-_54673901 0.056 NM_012117
CBX5
chromobox homolog 5
chr4_+_39046198 0.056 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr6_-_36515245 0.056 NM_007271
STK38
serine/threonine kinase 38
chr14_+_78870092 0.056 NM_004796
NRXN3
neurexin 3
chr6_-_128841432 0.056 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr8_-_145559831 0.056 NM_031309
SCRT1
scratch homolog 1, zinc finger protein (Drosophila)
chr11_-_78128852 0.055 NM_080491
GAB2
GRB2-associated binding protein 2
chr12_-_56615484 0.055 NM_001242826
RNF41
ring finger protein 41
chr9_+_34958171 0.054 NM_015297
KIAA1045
KIAA1045
chr5_+_49962771 0.054 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr22_+_24666749 0.054 NM_001145468
NM_015330
SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1-like

chr4_-_6565326 0.054 NM_001206994
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr4_-_6557404 0.054 NM_001206995
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr22_+_25202135 0.054 NM_001039948
NM_001098497
NM_001098498
NM_133454
SGSM1



small G protein signaling modulator 1



chr12_-_22487566 0.053 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_+_118401755 0.053 NM_001144034
NM_001144035
NM_001144036
NM_001144037
NM_001144038
NM_032780
TMEM25





transmembrane protein 25





chr10_+_112257624 0.052 NM_004419
DUSP5
dual specificity phosphatase 5
chr4_+_52709165 0.052 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr21_+_35445808 0.051 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr6_+_136172802 0.051 NM_018945
PDE7B
phosphodiesterase 7B
chrX_+_51075082 0.051 NM_153183
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr4_+_39063851 0.051 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr1_+_9352931 0.050 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr9_-_127905715 0.050 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr21_-_34100228 0.049 NM_001160302
NM_001160306
SYNJ1

synaptojanin 1

chr12_-_71182699 0.048 NM_001207015
PTPRR
protein tyrosine phosphatase, receptor type, R
chr17_+_42264300 0.048 NM_001076674
NM_024107
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr12_+_94542239 0.048 NM_005761
PLXNC1
plexin C1
chr1_+_113010039 0.047 NM_004185
WNT2B
wingless-type MMTV integration site family, member 2B
chr2_+_45878912 0.046 NM_005400
PRKCE
protein kinase C, epsilon
chr3_-_69435429 0.046 NM_015123
FRMD4B
FERM domain containing 4B
chr4_+_95679075 0.046 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_+_28832454 0.045 NM_001048199
RCC1
regulator of chromosome condensation 1
chr4_-_6422844 0.045 NM_001206996
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr8_+_22224997 0.044 NM_001135153
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr3_+_151985828 0.044 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr7_-_71877359 0.044 NM_031468
CALN1
calneuron 1
chr19_-_55954229 0.044 NM_001145176
SHISA7
shisa homolog 7 (Xenopus laevis)
chr7_+_106685007 0.044 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr14_+_85996454 0.044 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr17_+_60556247 0.043 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr4_+_38665587 0.043 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr3_-_53079285 0.043 NM_001005159
SFMBT1
Scm-like with four mbt domains 1
chr1_-_57045235 0.043 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr7_+_155089483 0.043 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr21_-_34100316 0.043 NM_003895
NM_203446
SYNJ1

synaptojanin 1

chr6_-_37665631 0.042 NM_153487
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 6.10e-09 GO:0050794 regulation of cellular process
1.35 6.23e-09 GO:0065007 biological regulation
1.35 3.46e-08 GO:0050789 regulation of biological process
1.53 4.19e-06 GO:0023052 signaling
1.88 4.56e-05 GO:0007399 nervous system development
2.06 5.81e-04 GO:0022008 neurogenesis
1.77 1.20e-03 GO:0009653 anatomical structure morphogenesis
3.21 1.55e-03 GO:0030168 platelet activation
1.66 2.24e-03 GO:0006464 protein modification process
1.44 3.08e-03 GO:0007165 signal transduction
1.63 3.30e-03 GO:0043412 macromolecule modification
1.15 5.54e-03 GO:0009987 cellular process
1.99 5.75e-03 GO:0048699 generation of neurons
2.33 8.14e-03 GO:0019226 transmission of nerve impulse
2.33 8.14e-03 GO:0035637 multicellular organismal signaling
1.74 8.32e-03 GO:0035556 intracellular signal transduction
1.39 9.55e-03 GO:0032502 developmental process
2.02 1.22e-02 GO:0007267 cell-cell signaling
1.86 1.33e-02 GO:0007154 cell communication
2.39 1.33e-02 GO:0007268 synaptic transmission
2.07 1.38e-02 GO:0009790 embryo development
1.30 1.54e-02 GO:0032501 multicellular organismal process
2.09 1.65e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.24 1.97e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.39 3.30e-02 GO:0007275 multicellular organismal development
2.44 3.46e-02 GO:0043009 chordate embryonic development
1.41 3.63e-02 GO:0048856 anatomical structure development
2.41 4.25e-02 GO:0009792 embryo development ending in birth or egg hatching
1.32 4.72e-02 GO:0044260 cellular macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.61 1.64e-04 GO:0045202 synapse
2.88 2.76e-04 GO:0044456 synapse part
2.11 3.01e-03 GO:0030054 cell junction
1.07 4.03e-03 GO:0044464 cell part
1.07 4.10e-03 GO:0005623 cell
1.13 7.15e-03 GO:0005622 intracellular
1.13 1.31e-02 GO:0044424 intracellular part
1.19 3.48e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.83 1.21e-02 GO:0004842 ubiquitin-protein ligase activity
2.67 2.75e-02 GO:0019787 small conjugating protein ligase activity
1.20 4.00e-02 GO:0005515 protein binding