Motif ID: UUGGCAC

Z-value: 0.578


Mature miRNA associated with seed UUGGCAC:

NamemiRBase Accession
hsa-miR-1271 MIMAT0005796
hsa-miR-96 MIMAT0000095



Activity profile for motif UUGGCAC.

activity profile for motif UUGGCAC


Sorted Z-values histogram for motif UUGGCAC

Sorted Z-values for motif UUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_68165660 0.282 NM_000891
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_55095263 0.227 NM_006206
 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr9_+_2621740 0.222 NM_001018056
NM_003383
 VLDLR

very low density lipoprotein receptor

chr5_-_172756505 0.219 NM_003714
 STC2
stanniocalcin 2
chr2_+_103236147 0.215 NM_003048
 SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr1_-_86043932 0.200 NM_001134445
 DDAH1
dimethylarginine dimethylaminohydrolase 1
chrX_+_30671456 0.197 NM_000167
NM_001128127
NM_001205019
NM_203391
 GK



glycerol kinase



chr1_-_85930733 0.191 NM_012137
 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr20_+_44650260 0.184 NM_001134771
 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chrX_-_107019001 0.182 NM_198057
 TSC22D3
TSC22 domain family, member 3
chr17_+_47074749 0.181 NM_001160423
NM_006546
 IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chrX_-_106960268 0.179 NM_004089
 TSC22D3
TSC22 domain family, member 3
chr20_+_44657812 0.176 NM_020708
 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr17_+_34136437 0.175 NM_003487
NM_139215
 TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

chr12_-_96184510 0.172 NM_021229
 NTN4
netrin 4
chr10_+_31608097 0.171 NM_001174093
NM_001174095
NM_001174096
NM_030751
 ZEB1



zinc finger E-box binding homeobox 1



chr12_+_78225068 0.167 NM_014903
 NAV3
neuron navigator 3
chr8_-_11324184 0.164 NM_053279
 FAM167A
family with sequence similarity 167, member A
chr6_-_30710219 0.160 NM_005803
 FLOT1
flotillin 1
chr12_+_32654976 0.160 NM_139241
 FGD4
FYVE, RhoGEF and PH domain containing 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
3.81 1.48e-02 GO:0007265 Ras protein signal transduction
3.43 1.38e-04 GO:0048011 nerve growth factor receptor signaling pathway
3.11 9.31e-04 GO:0030036 actin cytoskeleton organization
2.75 3.21e-02 GO:0046578 regulation of Ras protein signal transduction
2.68 1.35e-02 GO:0030029 actin filament-based process
2.54 5.54e-03 GO:0051056 regulation of small GTPase mediated signal transduction
2.43 1.30e-02 GO:0007264 small GTPase mediated signal transduction
2.36 1.68e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.27 1.00e-02 GO:0043549 regulation of kinase activity
2.20 2.15e-02 GO:0051338 regulation of transferase activity
2.20 2.62e-02 GO:0007010 cytoskeleton organization
2.04 5.29e-03 GO:0006468 protein phosphorylation
2.01 1.94e-04 GO:0006793 phosphorus metabolic process
2.01 1.94e-04 GO:0006796 phosphate metabolic process
1.93 1.51e-05 GO:0035556 intracellular signal transduction
1.92 1.31e-03 GO:0032268 regulation of cellular protein metabolic process
1.86 3.37e-07 GO:0006464 protein modification process
1.84 4.68e-03 GO:0051246 regulation of protein metabolic process
1.79 3.20e-06 GO:0043412 macromolecule modification
1.73 2.14e-03 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
9.66 3.29e-02 GO:0034706 sodium channel complex
3.79 4.42e-02 GO:0030027 lamellipodium
3.08 4.53e-03 GO:0031252 cell leading edge
2.78 2.94e-02 GO:0030425 dendrite
2.54 2.21e-04 GO:0045202 synapse
2.50 4.68e-04 GO:0043005 neuron projection
1.99 1.17e-02 GO:0030054 cell junction
1.88 2.67e-03 GO:0042995 cell projection
1.80 1.79e-02 GO:0005626 insoluble fraction
1.73 1.11e-04 GO:0005856 cytoskeleton
1.63 7.29e-05 GO:0005829 cytosol
1.36 3.96e-02 GO:0043234 protein complex
1.26 1.39e-06 GO:0005737 cytoplasm
1.24 9.19e-03 GO:0044444 cytoplasmic part
1.16 2.33e-05 GO:0044424 intracellular part
1.15 9.52e-05 GO:0005622 intracellular
1.07 1.04e-02 GO:0044464 cell part
1.07 1.05e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
7.56 4.06e-02 GO:0030971 receptor tyrosine kinase binding
2.75 9.44e-04 GO:0005083 small GTPase regulator activity
2.56 2.32e-02 GO:0005096 GTPase activator activity
2.53 4.97e-06 GO:0008092 cytoskeletal protein binding
2.49 5.69e-03 GO:0003779 actin binding
2.29 2.24e-03 GO:0030695 GTPase regulator activity
2.26 5.12e-03 GO:0019904 protein domain specific binding
2.22 4.00e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.21 1.05e-02 GO:0004674 protein serine/threonine kinase activity
2.05 5.39e-03 GO:0004672 protein kinase activity
2.01 1.32e-03 GO:0019899 enzyme binding
1.92 5.53e-04 GO:0030234 enzyme regulator activity
1.89 1.51e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.88 9.86e-03 GO:0016301 kinase activity
1.79 1.35e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.36 6.81e-10 GO:0005515 protein binding
1.14 4.25e-04 GO:0005488 binding