Motif ID: UUGUUCG

Z-value: 0.424


Mature miRNA associated with seed UUGUUCG:

NamemiRBase Accession
hsa-miR-375 MIMAT0000728



Activity profile for motif UUGUUCG.

activity profile for motif UUGUUCG


Sorted Z-values histogram for motif UUGUUCG

Sorted Z-values for motif UUGUUCG



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGUUCG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_136834887 0.338 NM_004598
 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr5_+_95066628 0.292 NM_014899
 RHOBTB3
Rho-related BTB domain containing 3
chr1_+_78956727 0.276 NM_000959
NM_001039585
 PTGFR

prostaglandin F receptor (FP)

chr8_-_122653493 0.260 NM_005328
 HAS2
hyaluronan synthase 2
chr1_+_79086087 0.247 NM_006820
 IFI44L
interferon-induced protein 44-like
chr8_+_77593506 0.220 NM_024721
 ZFHX4
zinc finger homeobox 4
chrX_+_16964730 0.203 NM_001080975
NM_004726
 REPS2

RALBP1 associated Eps domain containing 2

chr1_-_232651227 0.187 NM_020808
 SIPA1L2
signal-induced proliferation-associated 1 like 2
chr1_+_89990396 0.183 NM_001134476
 LRRC8B
leucine rich repeat containing 8 family, member B
chr14_-_30396811 0.178 NM_002742
 PRKD1
protein kinase D1
chr2_-_214016332 0.168 NM_001079526
 IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_+_148415657 0.167 NM_000685
NM_004835
NM_009585
NM_031850
 AGTR1



angiotensin II receptor, type 1



chr3_+_148447966 0.167 NM_032049
 AGTR1
angiotensin II receptor, type 1
chr17_+_38599651 0.163 NM_001552
 IGFBP4
insulin-like growth factor binding protein 4
chr1_+_90024271 0.159 NM_015350
 LRRC8B
leucine rich repeat containing 8 family, member B
chr9_+_4985243 0.155 NM_004972
 JAK2
Janus kinase 2
chr7_-_131241321 0.153 NM_001018111
NM_005397
 PODXL

podocalyxin-like

chr1_-_57045235 0.131 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_208417635 0.125 NM_025179
 PLXNA2
plexin A2
chr10_-_64028457 0.120 NM_145307
 RTKN2
rhotekin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
13.91 2.81e-02 GO:0060323 head morphogenesis
11.13 1.72e-02 GO:0060322 head development
3.58 3.71e-02 GO:0001655 urogenital system development
2.31 2.75e-02 GO:0031175 neuron projection development
2.16 1.43e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.09 1.13e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.95 2.82e-02 GO:0009891 positive regulation of biosynthetic process
1.81 1.67e-02 GO:0031325 positive regulation of cellular metabolic process
1.80 2.91e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.77 2.35e-02 GO:0009893 positive regulation of metabolic process
1.70 2.31e-02 GO:0009653 anatomical structure morphogenesis
1.62 1.32e-02 GO:0043412 macromolecule modification
1.62 1.98e-02 GO:0006464 protein modification process
1.53 4.37e-03 GO:0009889 regulation of biosynthetic process
1.52 7.66e-03 GO:0031326 regulation of cellular biosynthetic process
1.51 3.52e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.50 3.66e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.49 7.90e-04 GO:0007275 multicellular organismal development
1.48 1.54e-02 GO:0048731 system development
1.44 1.80e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
3.16 4.32e-02 GO:0045121 membrane raft
1.56 4.32e-02 GO:0012505 endomembrane system
1.12 2.49e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
13.91 6.05e-03 GO:0043548 phosphatidylinositol 3-kinase binding