Motif ID: UUUUUGC

Z-value: 2.052


Mature miRNA associated with seed UUUUUGC:

NamemiRBase Accession
hsa-miR-129-5p MIMAT0000242



Activity profile for motif UUUUUGC.

activity profile for motif UUUUUGC


Sorted Z-values histogram for motif UUUUUGC

Sorted Z-values for motif UUUUUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUUUUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_143550395 1.523 NM_020768
KCTD16
potassium channel tetramerisation domain containing 16
chr1_-_72748147 1.454 NM_173808
NEGR1
neuronal growth regulator 1
chr3_+_157154579 1.356 NM_002852
PTX3
pentraxin 3, long
chr1_+_89990396 1.354 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr1_+_90024271 1.171 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr6_-_46293628 1.153 NM_005822
RCAN2
regulator of calcineurin 2
chr1_-_236228476 1.125 NM_002508
NID1
nidogen 1
chr2_+_238395863 1.084 NM_001042467
NM_024101
MLPH

melanophilin

chr18_-_65183922 1.065 NM_032160
DSEL
dermatan sulfate epimerase-like
chr1_+_159141376 1.059 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr5_+_71403040 1.048 NM_005909
MAP1B
microtubule-associated protein 1B
chr5_+_149340287 1.000 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr1_+_79086087 0.997 NM_006820
IFI44L
interferon-induced protein 44-like
chr9_-_136344182 0.995 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr11_+_58874614 0.966 NM_001142703
NM_001142704
NM_198947
FAM111B


family with sequence similarity 111, member B


chr5_+_95066628 0.956 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr8_+_17354562 0.941 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr2_+_201997687 0.938 NM_001202518
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_+_82767492 0.909 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr11_-_74109417 0.903 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr9_+_91606349 0.894 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr15_+_89631380 0.887 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chr3_-_141944441 0.887 NM_001039547
GK5
glycerol kinase 5 (putative)
chr11_-_61584451 0.884 NM_013402
FADS1
fatty acid desaturase 1
chr14_-_61115906 0.839 NM_005982
SIX1
SIX homeobox 1
chr5_-_136834887 0.834 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr5_-_55290601 0.823 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr1_+_155829259 0.806 NM_152280
SYT11
synaptotagmin XI
chr21_-_28217692 0.805 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_-_89918531 0.789 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr2_+_204103163 0.779 NM_177538
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr18_-_57364643 0.776 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr17_-_42907606 0.772 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr2_+_202004997 0.770 NM_001202515
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_+_102073953 0.769 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr22_+_38092994 0.766 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr1_-_92351613 0.751 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr1_-_92371558 0.751 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr5_+_134209426 0.748 NM_024715
TXNDC15
thioredoxin domain containing 15
chr17_-_42908178 0.745 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr14_+_104394751 0.742 NM_153046
TDRD9
tudor domain containing 9
chr2_-_214016332 0.741 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_-_9546157 0.736 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr2_+_201983268 0.734 NM_001127183
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_+_17396285 0.704 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chrX_+_16964730 0.683 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr1_-_160001723 0.679 NM_145167
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr12_-_96184510 0.677 NM_021229
NTN4
netrin 4
chr8_-_60031545 0.675 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr6_-_52441815 0.665 NM_012288
TRAM2
translocation associated membrane protein 2
chr3_-_9994057 0.660 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr8_+_120428551 0.655 NM_002514
NOV
nephroblastoma overexpressed gene
chr2_-_74710356 0.649 NM_032779
CCDC142
coiled-coil domain containing 142
chr7_-_25164902 0.644 NM_018947
CYCS
cytochrome c, somatic
chr8_+_1711869 0.636 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr10_+_91092238 0.635 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr7_-_131241321 0.629 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr5_-_121412805 0.627 NM_001178102
LOX
lysyl oxidase
chr7_+_100770378 0.625 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr13_-_67804432 0.619 NM_020403
NM_203487
PCDH9

protocadherin 9

chr5_-_121414011 0.616 NM_002317
LOX
lysyl oxidase
chr10_+_70847817 0.612 NM_002727
SRGN
serglycin
chr5_-_75919051 0.611 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr12_-_31743822 0.609 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr12_+_65672682 0.605 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr6_-_153452383 0.605 NM_012419
RGS17
regulator of G-protein signaling 17
chr2_+_102770401 0.605 NM_000877
IL1R1
interleukin 1 receptor, type I
chr4_+_123747815 0.601 NM_002006
FGF2
fibroblast growth factor 2 (basic)
chrX_-_142722869 0.598 NM_173078
SLITRK4
SLIT and NTRK-like family, member 4
chr2_+_201170603 0.596 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr6_-_74363689 0.595 NM_012434
SLC17A5
solute carrier family 17 (anion/sugar transporter), member 5
chr2_+_203241044 0.593 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr9_+_91605777 0.591 NM_001001938
NM_001142413
C9orf47

chromosome 9 open reading frame 47

chr21_-_34100228 0.575 NM_001160302
NM_001160306
SYNJ1

synaptojanin 1

chr12_+_65672422 0.572 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr1_+_38259458 0.566 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr11_+_46299161 0.564 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr16_+_12995454 0.561 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr12_-_69326946 0.561 NM_001005502
NM_198320
CPM

carboxypeptidase M

chr6_+_151646634 0.560 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr3_+_38537749 0.560 NM_001145464
NM_005107
EXOG

endo/exonuclease (5'-3'), endonuclease G-like

chr1_+_38261079 0.559 NM_152496
MANEAL
mannosidase, endo-alpha-like
chr6_+_111580481 0.555 NM_153369
KIAA1919
KIAA1919
chr6_+_151561094 0.554 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr21_-_34100316 0.553 NM_003895
NM_203446
SYNJ1

synaptojanin 1

chr1_-_154474524 0.552 NM_001010846
SHE
Src homology 2 domain containing E
chr22_+_44319618 0.552 NM_025225
PNPLA3
patatin-like phospholipase domain containing 3
chr12_+_75874512 0.552 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr8_-_38325241 0.548 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chrX_+_77166178 0.546 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr8_+_17780351 0.545 NM_006197
PCM1
pericentriolar material 1
chr12_-_66563782 0.543 NM_016056
TMBIM4
transmembrane BAX inhibitor motif containing 4
chr3_-_132441302 0.541 NM_153240
NPHP3-ACAD11
NPHP3
NPHP3-ACAD11 readthrough
nephronophthisis 3 (adolescent)
chr16_+_5121809 0.541 NM_019109
ALG1
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
chr8_-_38326351 0.535 NM_001174063
NM_001174064
NM_015850
NM_023105
NM_023106
NM_023110
FGFR1





fibroblast growth factor receptor 1





chr12_+_60083125 0.531 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr1_+_90098643 0.531 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr16_-_12897693 0.528 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr1_+_201617449 0.523 NM_020443
NAV1
neuron navigator 1
chr4_+_74606222 0.522 NM_000584
IL8
interleukin 8
chr19_+_21264952 0.514 NM_182515
ZNF714
zinc finger protein 714
chrX_-_142722318 0.513 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr1_+_32930638 0.512 NM_001145720
ZBTB8B
zinc finger and BTB domain containing 8B
chrX_-_19140581 0.511 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr2_-_203736223 0.511 NM_138468
ICA1L
islet cell autoantigen 1,69kDa-like
chr10_+_91087601 0.505 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_-_5095131 0.504 NM_032530
ZNF594
zinc finger protein 594
chr1_-_241799101 0.497 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr2_+_201170795 0.497 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr19_-_23578226 0.496 NM_003430
ZNF91
zinc finger protein 91
chr8_+_98656329 0.494 NM_178812
MTDH
metadherin
chr2_-_38303307 0.492 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr4_-_3534153 0.492 NM_002337
LRPAP1
low density lipoprotein receptor-related protein associated protein 1
chr4_+_55523906 0.491 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr2_+_109150807 0.490 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_+_108093558 0.490 NM_000051
ATM
ataxia telangiectasia mutated
chr22_-_39052579 0.489 NM_001013647
LOC646851
putative uncharacterized protein LOC388900
chr11_-_27743604 0.488 NM_170731
BDNF
brain-derived neurotrophic factor
chr12_-_69357019 0.485 NM_001874
CPM
carboxypeptidase M
chr12_-_56236614 0.485 NM_002429
MMP19
matrix metallopeptidase 19
chr1_+_201708940 0.482 NM_001167738
NAV1
neuron navigator 1
chr11_-_27721975 0.482 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr19_+_16999807 0.480 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr13_+_32605436 0.477 NM_023037
FRY
furry homolog (Drosophila)
chr2_+_201980873 0.476 NM_001127184
NM_001202516
NM_001202517
NM_001202519
NM_003879
CFLAR




CASP8 and FADD-like apoptosis regulator




chr2_+_109237679 0.476 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_214015053 0.475 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_+_178450775 0.474 NM_001136116
ZNF879
zinc finger protein 879
chr7_-_141646716 0.472 NM_013252
CLEC5A
C-type lectin domain family 5, member A
chr7_-_92747317 0.470 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr11_-_27681195 0.465 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr11_-_27721179 0.461 NM_170734
BDNF
brain-derived neurotrophic factor
chr11_-_27723061 0.460 NM_170733
BDNF
brain-derived neurotrophic factor
chr19_+_2476122 0.459 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr3_+_42947649 0.457 NM_001134656
ZNF662
zinc finger protein 662
chr6_+_158589378 0.457 NM_207118
GTF2H5
general transcription factor IIH, polypeptide 5
chr16_+_15596122 0.456 NM_001142469
C16orf45
chromosome 16 open reading frame 45
chr1_+_213123853 0.456 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr22_+_17565844 0.455 NM_014339
IL17RA
interleukin 17 receptor A
chr8_+_38585703 0.455 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr5_-_36151953 0.454 NM_001007527
LMBRD2
LMBR1 domain containing 2
chrX_-_142723921 0.450 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr11_-_27722446 0.450 NM_001143812
BDNF
brain-derived neurotrophic factor
chr3_+_42947401 0.448 NM_207404
ZNF662
zinc finger protein 662
chr16_+_15528324 0.443 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr2_-_179343225 0.443 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr7_-_139477437 0.442 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr6_+_74405505 0.440 NM_001159587
NM_001159588
NM_133493
CD109


CD109 molecule


chr3_+_99357439 0.439 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr4_-_175443791 0.439 NM_000860
NM_001145816
HPGD

hydroxyprostaglandin dehydrogenase 15-(NAD)

chr11_-_27722599 0.438 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor



chr11_-_27741192 0.435 NM_001143807
BDNF
brain-derived neurotrophic factor
chr19_-_39368889 0.435 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr11_-_27742224 0.434 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr2_-_127963342 0.434 NM_001001665
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr8_+_38644721 0.428 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr4_-_185747183 0.427 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr2_+_128848752 0.425 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chrX_-_77041678 0.425 NM_000489
NM_138270
ATRX

alpha thalassemia/mental retardation syndrome X-linked

chr19_-_53233134 0.421 NM_030972
ZNF611
zinc finger protein 611
chr19_-_37406918 0.419 NM_001171979
ZNF829
zinc finger protein 829
chr11_+_133938819 0.418 NM_001205329
NM_032801
JAM3

junctional adhesion molecule 3

chr12_+_32654976 0.414 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_+_109223600 0.412 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr18_-_712503 0.411 NM_202758
NM_001126123
NM_017512
ENOSF1


enolase superfamily member 1


chr10_-_64028457 0.411 NM_145307
RTKN2
rhotekin 2
chr5_-_149535420 0.410 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr3_+_49449638 0.410 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr1_-_111217625 0.410 NM_002232
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr2_+_210288668 0.406 NM_001039538
MAP2
microtubule-associated protein 2
chr19_-_20748540 0.404 NM_001159293
ZNF737
zinc finger protein 737
chr17_+_3539761 0.404 NM_001031681
NM_004937
CTNS

cystinosin, lysosomal cystine transporter

chr16_-_18937722 0.404 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr9_-_113800243 0.404 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr5_+_131705353 0.404 NM_003060
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr11_-_8680382 0.402 NM_014818
TRIM66
tripartite motif containing 66
chr2_-_85555343 0.402 NM_001206840
NM_001206841
NM_001206844
NM_006464
TGOLN2



trans-golgi network protein 2



chr2_+_109271267 0.402 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_+_7069454 0.401 NM_001044387
NM_001044388
NM_024341
ZNF557


zinc finger protein 557


chr2_-_167232464 0.401 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr4_+_81187741 0.401 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr5_+_76011780 0.398 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr4_+_108852671 0.397 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr15_-_40633122 0.396 NM_207380
C15orf52
chromosome 15 open reading frame 52
chr16_-_54320367 0.395 NM_024336
IRX3
iroquois homeobox 3
chr12_-_115121939 0.395 NM_005996
NM_016569
TBX3

T-box 3

chr19_+_57078889 0.394 NM_001001668
ZNF470
zinc finger protein 470
chrX_-_83757398 0.393 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr1_-_109969058 0.392 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr4_+_88928797 0.388 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr3_+_197687070 0.387 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr15_-_49338496 0.386 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr17_-_74236272 0.383 NM_052916
RNF157
ring finger protein 157
chr4_-_125633716 0.381 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr2_+_210444364 0.381 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr12_-_53574379 0.378 NM_015989
CSAD
cysteine sulfinic acid decarboxylase
chr5_-_138775213 0.376 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chrX_+_119737743 0.375 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr18_+_9136742 0.372 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr3_+_40566341 0.371 NM_001098414
NM_198484
ZNF621

zinc finger protein 621


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.41 1.09e-03 GO:0012505 endomembrane system
1.05 2.34e-03 GO:0044464 cell part
1.05 2.41e-03 GO:0005623 cell
1.30 1.32e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.51 3.00e-08 GO:0008270 zinc ion binding
1.46 5.71e-08 GO:0046914 transition metal ion binding
1.29 8.82e-06 GO:0046872 metal ion binding
1.28 1.48e-05 GO:0043167 ion binding
1.28 1.60e-05 GO:0043169 cation binding