Motif ID: ZBTB16.p2

Z-value: 1.154


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB16chr11_+_113931228,
chr11_+_113930430,
chr11_+_113930296
0.472.4e-01Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_95244634 1.203 ASPN
asporin
chr1_+_145524989 1.144 NM_003637
ITGA10
integrin, alpha 10
chr9_-_95244750 1.134 NM_001193335
NM_017680
ASPN

asporin

chr4_-_159094163 0.831 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr12_-_15038724 0.771 NM_000900
NM_001190839
MGP

matrix Gla protein

chr11_+_5710816 0.755 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr8_-_120651019 0.644 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr4_+_71108304 0.622 NM_005212
CSN3
casein kappa
chr8_-_108510094 0.612 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_+_155853546 0.594 SYT11
synaptotagmin XI
chr1_-_182357871 0.553 GLUL
glutamate-ammonia ligase
chr17_-_66951381 0.551 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr21_-_31852631 0.506 NM_181607
KRTAP19-1
keratin associated protein 19-1
chrX_-_154250769 0.489 NM_000132
F8
coagulation factor VIII, procoagulant component
chr1_+_163041694 0.489 NM_001113380
RGS4
regulator of G-protein signaling 4
chr2_-_38303265 0.483 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr19_-_48752921 0.464 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr18_-_52626636 0.452 NM_025214
CCDC68
coiled-coil domain containing 68
chr12_-_10588543 0.446 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr2_-_38303307 0.423 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr17_-_39183453 0.417 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr6_+_27777713 0.405 NM_003536
HIST1H3H
histone cluster 1, H3h
chr8_-_93029864 0.403 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_161993465 0.400 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr1_-_144997110 0.396 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_48759141 0.394 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr3_+_45067750 0.382 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr4_-_69817478 0.381 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr10_+_49609641 0.380 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr19_+_20959109 0.378


chr16_+_27078218 0.376 NM_001145545
C16orf82
chromosome 16 open reading frame 82
chr9_-_95166827 0.371 NM_014057
NM_033014
OGN

osteoglycin

chr4_-_159093523 0.356 FAM198B
family with sequence similarity 198, member B
chr10_-_74283693 0.355 NM_001195519
MICU1
mitochondrial calcium uptake 1
chr12_+_10460416 0.354 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr13_-_38172862 0.353 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr3_-_169587598 0.353 NM_024727
LRRC31
leucine rich repeat containing 31
chr10_+_104613966 0.348 NM_001136200
NM_144591
C10orf32-AS3MT
C10orf32

C10orf32-AS3MT readthrough
chromosome 10 open reading frame 32

chr11_-_104916041 0.336 NM_001017534
NM_052889
CARD16

caspase recruitment domain family, member 16

chr3_-_93692898 0.330 NM_000313
PROS1
protein S (alpha)
chr5_-_158526698 0.324 NM_024007
EBF1
early B-cell factor 1
chr12_-_13248581 0.321 NM_001206843
NM_001206845
NM_031289
NM_153823
GSG1



germ cell associated 1



chr6_+_136172802 0.321 NM_018945
PDE7B
phosphodiesterase 7B
chr13_+_97928196 0.314 MBNL2
muscleblind-like 2 (Drosophila)
chr12_-_13256572 0.313 NM_001080554
NM_001080555
NM_001206842
GSG1


germ cell associated 1


chr18_+_61582744 0.312 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr5_+_71502700 0.310 MAP1B
microtubule-associated protein 1B
chr5_+_67588395 0.309 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr2_-_188419049 0.308 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr11_+_5710926 0.305 TRIM22
tripartite motif containing 22
chr1_+_78470593 0.295 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr19_+_3762650 0.293 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr9_+_105757592 0.291 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr12_-_10562142 0.290 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 readthrough
killer cell lectin-like receptor subfamily C, member 4
chr5_-_150521200 0.285 NM_001193544
ANXA6
annexin A6
chr1_+_145487301 0.285 LIX1L
Lix1 homolog (mouse)-like
chr1_+_53480573 0.282 NM_001007099
NM_001007100
NM_001007250
SCP2


sterol carrier protein 2


chr1_-_182357757 0.275 GLUL
glutamate-ammonia ligase
chr12_+_7942025 0.275 NANOG
Nanog homeobox
chr19_+_3762671 0.275 MRPL54
mitochondrial ribosomal protein L54
chr6_+_46761093 0.273 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr6_-_132967141 0.272 NM_138327
TAAR1
trace amine associated receptor 1
chr5_-_154230157 0.271 C5orf4
chromosome 5 open reading frame 4
chr19_+_37717365 0.268 NM_152604
ZNF383
zinc finger protein 383
chr18_-_56296188 0.266 NM_052947
ALPK2
alpha-kinase 2
chr9_-_21305311 0.265 NM_002169
IFNA5
interferon, alpha 5
chr17_-_67138013 0.265 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr15_+_72406598 0.262 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chr14_+_23067128 0.260 NM_022060
ABHD4
abhydrolase domain containing 4
chr6_-_117747017 0.258 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr10_+_111765725 0.256 NM_019903
ADD3
adducin 3 (gamma)
chr10_+_35426709 0.250 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr2_+_109237679 0.248 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr18_+_66465316 0.248 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr19_-_20607761 0.244 ZNF826P
zinc finger protein 826, pseudogene
chr1_+_196621007 0.244 NM_000186
NM_001014975
CFH

complement factor H

chr18_+_616671 0.243 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr10_+_70847817 0.242 NM_002727
SRGN
serglycin
chr13_-_49975734 0.238 NM_030925
CAB39L
calcium binding protein 39-like
chr16_-_4588738 0.236 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr3_+_12392993 0.234 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr11_+_65266642 0.233


chrX_-_102531673 0.231 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr4_-_70725792 0.231 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr4_-_48014960 0.229 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr3_+_159557745 0.229 SCHIP1
schwannomin interacting protein 1
chr16_-_12897632 0.228 CPPED1
calcineurin-like phosphoesterase domain containing 1
chr10_+_5136556 0.227 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr7_-_107770785 0.226 NM_007356
LAMB4
laminin, beta 4
chr2_+_152214105 0.226 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr10_+_5136589 0.226 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_-_49220213 0.225 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr4_+_74347461 0.225 NM_001133
AFM
afamin
chr5_+_147691988 0.224 NM_032566
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr12_-_10573041 0.224 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr13_-_33780142 0.224 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr11_+_63273523 0.222 NM_001142535
NM_001142536
NM_033101
LGALS12


lectin, galactoside-binding, soluble, 12


chr3_-_165555167 0.221 BCHE
butyrylcholinesterase
chr2_-_119605758 0.220 NM_001426
EN1
engrailed homeobox 1
chr20_-_18477811 0.220 NM_006606
RBBP9
retinoblastoma binding protein 9
chr22_+_38203899 0.220 NM_001171690
NM_014291
GCAT

glycine C-acetyltransferase

chr4_+_86699858 0.219 ARHGAP24
Rho GTPase activating protein 24
chr6_+_25962978 0.216 NM_006355
TRIM38
tripartite motif containing 38
chrX_-_49089770 0.214 NM_005183
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr10_+_5136613 0.214 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_-_15382874 0.212 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr2_+_61372206 0.212 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr3_+_151591428 0.212 NM_033050
SUCNR1
succinate receptor 1
chr11_+_63273555 0.211 LGALS12
lectin, galactoside-binding, soluble, 12
chr3_+_183353355 0.210 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr10_-_31288420 0.210 NM_001143769
ZNF438
zinc finger protein 438
chr6_-_76782204 0.209 NM_001563
IMPG1
interphotoreceptor matrix proteoglycan 1
chr9_-_21202201 0.208 NM_021057
IFNA7
interferon, alpha 7
chr10_+_8097350 0.206 GATA3
GATA binding protein 3
chr3_-_165555252 0.206 NM_000055
BCHE
butyrylcholinesterase
chr12_+_15699277 0.205 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr1_-_108786663 0.204 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr21_+_30452872 0.202 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr16_+_21695749 0.202 NM_001161683
OTOA
otoancorin
chr17_+_41158741 0.202 NM_005533
IFI35
interferon-induced protein 35
chr10_+_15085894 0.200 NM_001039702
NM_018324
OLAH

oleoyl-ACP hydrolase

chr21_-_35884503 0.198 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr12_-_46357949 0.198


chr2_+_24807345 0.197 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr1_+_53480616 0.197 SCP2
sterol carrier protein 2
chrX_+_71401525 0.194 NM_001170747
NM_006223
PIN4

protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)

chr5_+_67586466 0.192 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr9_+_131683173 0.192 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr17_+_39382878 0.192 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr19_+_13885278 0.189 C19orf53
chromosome 19 open reading frame 53
chr4_-_57522469 0.189 NM_001145459
NM_139211
HOPX

HOP homeobox

chr7_+_149570004 0.188 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chrX_+_109662284 0.187 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr3_+_159557649 0.187 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr6_-_26189303 0.187 NM_003539
HIST1H4D
histone cluster 1, H4d
chr15_-_99789585 0.187 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr2_+_88047603 0.186 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr2_+_170662044 0.186 SSB
Sjogren syndrome antigen B (autoantigen La)
chr6_+_132891460 0.186 NM_175067
TAAR6
trace amine associated receptor 6
chr20_-_45061554 0.186 ELMO2
engulfment and cell motility 2
chr11_-_70672644 0.186 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_+_79428335 0.185 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr22_+_29168679 0.184 CCDC117
coiled-coil domain containing 117
chr9_+_120466453 0.184 NM_138554
TLR4
toll-like receptor 4
chrX_+_100878101 0.183 NM_016607
NM_177947
ARMCX3

armadillo repeat containing, X-linked 3

chr9_-_95298251 0.182 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr12_-_91576579 0.182 DCN
decorin
chr19_-_54824343 0.181 NM_021250
NM_181879
NM_181985
NM_181986
LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr14_+_88471467 0.181 NM_003608
GPR65
G protein-coupled receptor 65
chr5_-_10308167 0.181 NM_138809
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr4_+_141264596 0.178 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr4_+_70861647 0.177 NM_001009181
NM_003154
STATH

statherin

chr3_-_138478184 0.176 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr2_-_87248942 0.175 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr12_+_12938540 0.174 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr8_+_42552561 0.174 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr4_+_175839508 0.173 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chr3_+_69915374 0.173 NM_198177
MITF
microphthalmia-associated transcription factor
chrY_-_6742028 0.171 NM_001143
AMELY
amelogenin, Y-linked
chr3_-_169487602 0.170 NM_032487
ARPM1
actin related protein M1
chr22_+_29168628 0.168 NM_173510
CCDC117
coiled-coil domain containing 117
chr5_+_141346401 0.167 NM_001201365
NM_183399
RNF14

ring finger protein 14

chr7_-_92777657 0.166 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr10_+_69869249 0.165 NM_032578
MYPN
myopalladin
chr5_+_304290 0.164 NM_001242412
NM_020731
AHRR

aryl-hydrocarbon receptor repressor

chr1_-_246580710 0.164 NM_022743
SMYD3
SET and MYND domain containing 3
chr10_+_124151818 0.163 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr3_-_100712248 0.162 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr7_-_84751246 0.161 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chrX_-_23855456 0.159 RPL9
ribosomal protein L9
chr11_+_65266980 0.158


chr10_-_72648540 0.157 NM_000281
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr7_+_22766765 0.157 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr5_+_148731226 0.157 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr11_+_55944093 0.157 NM_001005492
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chr3_-_126327397 0.157 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_+_140782367 0.157 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr6_+_5030202 0.156 LOC100129461
uncharacterized LOC100129461
chr5_+_35856990 0.156 NM_002185
IL7R
interleukin 7 receptor
chr1_+_171283372 0.156 NM_002022
FMO4
flavin containing monooxygenase 4
chr6_-_150212036 0.154 NM_001243325
NM_001243327
NM_139165
RAET1E


retinoic acid early transcript 1E


chr9_-_36375965 0.154 RNF38
ring finger protein 38
chr19_-_35085489 0.154 NM_001025591
SCGBL
secretoglobin-like
chr17_-_33390676 0.153 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr3_+_183165402 0.153 LOC100505687
uncharacterized LOC100505687
chr4_+_38869346 0.153 NM_138389
FAM114A1
family with sequence similarity 114, member A1
chr4_-_84035888 0.152 PLAC8
placenta-specific 8
chr12_-_10605928 0.149 NM_002259
NM_007328
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr16_-_12897693 0.149 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr8_-_27941387 0.148 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr11_+_5009420 0.148 NM_021801
MMP26
matrix metallopeptidase 26
chr19_+_35417806 0.146 NM_001099437
NM_001099438
NM_194325
ZNF30


zinc finger protein 30


chr11_+_63275458 0.146 NM_001142537
NM_001142538
LGALS12

lectin, galactoside-binding, soluble, 12

chr5_+_126859157 0.146 PRRC1
proline-rich coiled-coil 1
chr16_+_21689834 0.145 NM_144672
OTOA
otoancorin
chr2_-_211168315 0.145 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr11_+_5641173 0.144 NM_001003827
TRIM34
tripartite motif containing 34
chr1_-_244006885 0.144 NM_001206729
AKT3
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr13_-_101241007 0.142 NM_001195087
A2LD1
AIG2-like domain 1
chr12_-_91398744 0.142 EPYC
epiphycan

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.24 9.62e-05 GO:0045087 innate immune response
1.77 7.77e-04 GO:0006955 immune response
1.67 5.61e-03 GO:0006952 defense response
1.90 1.20e-02 GO:0050776 regulation of immune response
3.70 1.62e-02 GO:0001959 regulation of cytokine-mediated signaling pathway
2.56 1.77e-02 GO:0009615 response to virus
3.64 2.01e-02 GO:0060337 type I interferon-mediated signaling pathway
3.64 2.01e-02 GO:0060759 regulation of response to cytokine stimulus
3.64 2.01e-02 GO:0071357 cellular response to type I interferon
3.58 2.48e-02 GO:0034340 response to type I interferon
5.01 3.02e-02 GO:0060338 regulation of type I interferon-mediated signaling pathway
2.40 3.84e-02 GO:0045088 regulation of innate immune response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
11.28 1.08e-03 GO:0005132 interferon-alpha/beta receptor binding