Motif ID: ZBTB6.p2

Z-value: 1.473


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB6chr9_-_125675571-0.611.1e-01Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_52914080 4.243 NM_000424
 KRT5
keratin 5
chr12_-_52845862 4.089 NM_005555
 KRT6B
keratin 6B
chr1_+_43996478 3.812 NM_002840
NM_130440
 PTPRF

protein tyrosine phosphatase, receptor type, F

chr17_+_54671059 2.783 NM_005450
 NOG
noggin
chr12_-_52886971 2.625 NM_005554
 KRT6A
keratin 6A
chr5_-_149682447 2.266 NM_001012301
 ARSI
arylsulfatase family, member I
chr12_+_53342842 2.085 NM_000224
 KRT18
keratin 18
chr12_+_53342899 1.637 KRT18
keratin 18
chr19_-_36001336 1.576 NM_001126059
 DMKN
dermokine
chr4_+_1795004 1.524 NM_000142
NM_001163213
NM_022965
 FGFR3


fibroblast growth factor receptor 3


chr16_+_22825481 1.261 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_-_15090349 1.245 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr1_+_158150678 1.239 CD1D
CD1d molecule
chr20_+_6748744 1.226 NM_001200
 BMP2
bone morphogenetic protein 2
chr16_+_22825806 1.171 NM_006043
 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_-_242687997 1.163 NM_152666
 PLD5
phospholipase D family, member 5
chr1_+_26856259 1.151 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_+_104512975 1.134 NM_001100117
 RIMS2
regulating synaptic membrane exocytosis 2
chr5_-_141257943 1.101 NM_002587
NM_032420
 PCDH1

protocadherin 1

chr5_+_140220811 1.098 NM_018911
NM_031856
 PCDHA8

protocadherin alpha 8


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.53 6.62e-04 GO:0006468 protein phosphorylation
1.42 3.25e-03 GO:0006793 phosphorus metabolic process
1.42 3.25e-03 GO:0006796 phosphate metabolic process
1.42 2.63e-02 GO:0016310 phosphorylation
1.39 1.32e-06 GO:0006464 protein modification process
1.37 4.33e-06 GO:0043412 macromolecule modification
1.33 5.73e-03 GO:0007399 nervous system development
1.29 8.63e-05 GO:0044267 cellular protein metabolic process
1.29 8.66e-03 GO:0007166 cell surface receptor linked signaling pathway
1.24 8.36e-06 GO:0023052 signaling
1.24 1.09e-03 GO:0019538 protein metabolic process
1.23 2.35e-04 GO:0007165 signal transduction
1.18 4.82e-02 GO:0051179 localization
1.17 5.74e-03 GO:0044260 cellular macromolecule metabolic process
1.16 6.43e-03 GO:0043170 macromolecule metabolic process
1.12 2.58e-10 GO:0009987 cellular process
1.10 3.21e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
3.75 4.56e-02 GO:0044304 main axon
2.19 3.39e-02 GO:0042470 melanosome
2.19 3.39e-02 GO:0048770 pigment granule
1.65 2.03e-03 GO:0009986 cell surface
1.53 3.61e-02 GO:0045202 synapse
1.44 1.55e-06 GO:0031226 intrinsic to plasma membrane
1.44 3.19e-06 GO:0005887 integral to plasma membrane
1.37 1.53e-08 GO:0044459 plasma membrane part
1.19 3.32e-07 GO:0031224 intrinsic to membrane
1.19 3.58e-07 GO:0016021 integral to membrane
1.18 1.55e-08 GO:0044425 membrane part
1.15 4.48e-08 GO:0016020 membrane
1.15 1.41e-02 GO:0005886 plasma membrane
1.15 2.13e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
5.84 1.97e-02 GO:0003756 protein disulfide isomerase activity
5.84 1.97e-02 GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups
5.84 1.97e-02 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds
2.32 3.16e-02 GO:0005275 amine transmembrane transporter activity
1.89 9.65e-03 GO:0005244 voltage-gated ion channel activity
1.89 9.65e-03 GO:0022832 voltage-gated channel activity
1.70 6.78e-03 GO:0022836 gated channel activity
1.56 3.53e-02 GO:0005216 ion channel activity
1.50 4.07e-03 GO:0004672 protein kinase activity
1.47 2.64e-02 GO:0008324 cation transmembrane transporter activity
1.44 1.02e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.42 1.52e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.39 6.83e-03 GO:0022857 transmembrane transporter activity
1.39 4.32e-02 GO:0015075 ion transmembrane transporter activity
1.33 4.67e-02 GO:0022892 substrate-specific transporter activity
1.26 4.61e-02 GO:0032559 adenyl ribonucleotide binding
1.26 4.89e-02 GO:0030554 adenyl nucleotide binding
1.25 4.40e-02 GO:0016740 transferase activity
1.15 7.12e-07 GO:0005515 protein binding