Motif ID: ZEB1.p2

Z-value: 4.054


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_31608097-0.974.0e-05Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_38755097 15.853 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38755422 15.789 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755238 15.626 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr7_+_26331493 12.220 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr16_+_68771192 12.137 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_+_60280462 11.993 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr2_+_47596286 11.511 NM_002354
EPCAM
epithelial cell adhesion molecule
chr16_+_68771214 11.368 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_+_47596447 11.179 EPCAM
epithelial cell adhesion molecule
chr11_+_32851469 11.138 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_+_35739519 11.048 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr19_+_35739778 10.721 LSR
lipolysis stimulated lipoprotein receptor
chr8_+_95653272 10.320 ESRP1
epithelial splicing regulatory protein 1
chr1_+_1981902 10.224 NM_002744
PRKCZ
protein kinase C, zeta
chr14_-_61747956 9.987 TMEM30B
transmembrane protein 30B
chr19_+_6464259 9.648 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr7_+_26331611 9.263 SNX10
sorting nexin 10
chr19_+_35739282 8.769 LSR
lipolysis stimulated lipoprotein receptor
chr22_+_40390935 8.204 NM_138435
FAM83F
family with sequence similarity 83, member F
chr8_+_120220554 7.974 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.15 3.88e-02 GO:0045216 cell-cell junction organization
1.18 5.33e-04 GO:0023052 signaling
1.18 6.06e-03 GO:0007165 signal transduction
1.15 1.83e-02 GO:0051716 cellular response to stimulus
1.08 1.81e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.73 6.88e-03 GO:0005911 cell-cell junction
1.34 4.33e-02 GO:0031967 organelle envelope
1.34 4.79e-02 GO:0005789 endoplasmic reticulum membrane
1.31 2.66e-05 GO:0012505 endomembrane system
1.31 4.52e-03 GO:0005783 endoplasmic reticulum
1.26 4.89e-05 GO:0031090 organelle membrane
1.13 6.38e-05 GO:0044444 cytoplasmic part
1.12 7.06e-08 GO:0005737 cytoplasm
1.11 9.10e-03 GO:0044446 intracellular organelle part
1.11 2.90e-02 GO:0044422 organelle part
1.10 7.28e-04 GO:0016020 membrane
1.08 2.58e-03 GO:0043231 intracellular membrane-bounded organelle
1.08 2.86e-03 GO:0043227 membrane-bounded organelle
1.07 6.94e-06 GO:0005622 intracellular
1.07 1.18e-04 GO:0044424 intracellular part
1.07 3.68e-02 GO:0043229 intracellular organelle
1.06 4.16e-02 GO:0043226 organelle
1.04 2.78e-03 GO:0044464 cell part
1.04 2.92e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.10 2.30e-02 GO:0015294 solute:cation symporter activity
2.09 4.83e-02 GO:0005275 amine transmembrane transporter activity
1.26 1.18e-03 GO:0016740 transferase activity
1.25 6.02e-04 GO:0017076 purine nucleotide binding
1.25 6.21e-04 GO:0032553 ribonucleotide binding
1.25 6.21e-04 GO:0032555 purine ribonucleotide binding
1.25 9.96e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.24 2.80e-02 GO:0005524 ATP binding
1.24 2.95e-02 GO:0032559 adenyl ribonucleotide binding
1.23 3.43e-02 GO:0030554 adenyl nucleotide binding
1.19 1.69e-02 GO:0000166 nucleotide binding
1.12 1.54e-05 GO:0005515 protein binding
1.11 2.22e-02 GO:0003824 catalytic activity