Motif ID: ZNF423.p2

Z-value: 0.339


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_498609170.265.4e-01Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_100027943 0.319 NM_032211
LOXL4
lysyl oxidase-like 4
chr4_+_74735107 0.261 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr21_+_47531369 0.238 COL6A2
collagen, type VI, alpha 2
chr5_+_92920592 0.231 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr1_-_184943532 0.229 FAM129A
family with sequence similarity 129, member A
chr19_+_14544100 0.213 NM_002741
PKN1
protein kinase N1
chrX_+_152770083 0.196 BGN
biglycan
chr19_+_14544216 0.178 PKN1
protein kinase N1
chr11_+_92702788 0.173 NM_005959
MTNR1B
melatonin receptor 1B
chr5_-_137368682 0.165 FAM13B
family with sequence similarity 13, member B
chr5_-_136834887 0.158 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr21_+_26934440 0.157 MIR155HG
MIR155 host gene (non-protein coding)
chr8_+_17433941 0.155 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr22_-_24640850 0.153 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chrX_-_19140581 0.151 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr1_+_210406194 0.149 NM_019605
SERTAD4
SERTA domain containing 4
chr5_+_78407603 0.147 NM_001713
BHMT
betaine--homocysteine S-methyltransferase
chr12_+_59989847 0.142 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr5_-_137368778 0.130 NM_001101800
NM_001101801
NM_016603
FAM13B


family with sequence similarity 13, member B


chr2_-_145275086 0.126 ZEB2
zinc finger E-box binding homeobox 2
chr6_+_39760138 0.125


chr20_+_44462788 0.123 SNX21
sorting nexin family member 21
chr22_+_21737662 0.122 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr8_+_120428551 0.121 NM_002514
NOV
nephroblastoma overexpressed gene
chr12_-_29936685 0.119 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr14_-_60097314 0.117 RTN1
reticulon 1
chr20_+_44462395 0.117 NM_001042632
NM_001042633
NM_033421
NM_152897
SNX21



sorting nexin family member 21



chr17_+_80190107 0.116 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr1_-_212873197 0.116 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr22_-_21905749 0.110 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr19_-_5622725 0.110 SAFB2
scaffold attachment factor B2
chr14_-_60097531 0.108 NM_206852
RTN1
reticulon 1
chr1_+_36549675 0.108 NM_014466
TEKT2
tektin 2 (testicular)
chr1_-_212873306 0.108 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr19_+_12273866 0.106 NM_003437
ZNF136
zinc finger protein 136
chr17_-_76921453 0.105 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chrX_+_30265270 0.104 NM_177404
MAGEB1
melanoma antigen family B, 1
chr12_+_79258588 0.104 SYT1
synaptotagmin I
chr6_+_151561094 0.103 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr6_-_52441714 0.098 TRAM2
translocation associated membrane protein 2
chr2_+_189157551 0.098 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr15_+_90931509 0.097 IQGAP1
IQ motif containing GTPase activating protein 1
chr3_+_32280211 0.097 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr3_+_32280154 0.097 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr7_-_50860665 0.096 GRB10
growth factor receptor-bound protein 10
chr6_+_151561653 0.096 AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_61595633 0.094 NM_004265
FADS2
fatty acid desaturase 2
chr8_+_1712011 0.094 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr15_+_90931489 0.093 IQGAP1
IQ motif containing GTPase activating protein 1
chr5_+_96271345 0.092 NM_005575
LNPEP
leucyl/cystinyl aminopeptidase
chr5_+_96271086 0.090 LNPEP
leucyl/cystinyl aminopeptidase
chr8_+_1711869 0.090 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr9_-_97401588 0.090 FBP1
fructose-1,6-bisphosphatase 1
chr9_+_4985243 0.089 NM_004972
JAK2
Janus kinase 2
chr14_-_53417636 0.089 FERMT2
fermitin family member 2
chr5_+_153570270 0.089 NM_198321
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr19_+_36359346 0.089 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr14_-_60097223 0.089 RTN1
reticulon 1
chr21_-_46962281 0.089 NM_001205206
NM_194255
SLC19A1

solute carrier family 19 (folate transporter), member 1

chr17_+_44076615 0.087 NM_001007532
STH
saitohin
chr19_-_5622794 0.087 NM_014649
SAFB2
scaffold attachment factor B2
chr5_+_32711437 0.086 NM_000908
NM_001204375
NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr8_-_101158027 0.085 NM_001029860
FBXO43
F-box protein 43
chr3_-_16555128 0.085 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr2_+_202899309 0.085 NM_003507
FZD7
frizzled family receptor 7
chr18_-_19284737 0.085 NM_138340
ABHD3
abhydrolase domain containing 3
chr4_+_4388717 0.084 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr5_+_118406721 0.084 DMXL1
Dmx-like 1
chr3_-_48594209 0.084 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr19_-_11849730 0.084 NM_001080493
ZNF823
zinc finger protein 823
chr7_+_142985462 0.083 CASP2
caspase 2, apoptosis-related cysteine peptidase
chr4_-_74964836 0.082 CXCL2
chemokine (C-X-C motif) ligand 2
chr19_-_1812198 0.082 NM_001178002
NM_138813
ATP8B3

ATPase, aminophospholipid transporter, class I, type 8B, member 3

chr4_-_129208967 0.080 PGRMC2
progesterone receptor membrane component 2
chr12_-_6665220 0.080 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr20_+_36531548 0.079 VSTM2L
V-set and transmembrane domain containing 2 like
chr6_-_52441815 0.079 NM_012288
TRAM2
translocation associated membrane protein 2
chr20_-_30458010 0.079 NM_177991
DUSP15
dual specificity phosphatase 15
chr3_-_50374749 0.079 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr18_-_19284622 0.078 ABHD3
abhydrolase domain containing 3
chr12_+_56661026 0.078 NM_001099337
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr2_-_120980971 0.078 NM_024121
TMEM185B
transmembrane protein 185B
chr3_-_50374795 0.077 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr3_+_9958757 0.077 NM_001203263
NM_001203264
NM_001203265
NM_032732
NM_153460
NM_153461
IL17RC





interleukin 17 receptor C





chr15_+_90931449 0.077 IQGAP1
IQ motif containing GTPase activating protein 1
chr3_-_50374875 0.077 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr22_+_35777051 0.076 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr3_-_58563070 0.076 FAM107A
family with sequence similarity 107, member A
chr3_-_16554992 0.075 RFTN1
raftlin, lipid raft linker 1
chr4_-_129208964 0.075 PGRMC2
progesterone receptor membrane component 2
chr9_+_136243226 0.074 NM_153710
C9orf96
chromosome 9 open reading frame 96
chr20_+_36531498 0.074 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr17_-_64187814 0.074 NM_145036
NM_001199165
CEP112

centrosomal protein 112kDa

chr12_+_79258448 0.074 NM_005639
SYT1
synaptotagmin I
chr15_-_90347173 0.073 ANPEP
alanyl (membrane) aminopeptidase
chr6_-_74363689 0.073 NM_012434
SLC17A5
solute carrier family 17 (anion/sugar transporter), member 5
chr15_+_90931470 0.072 NM_003870
IQGAP1
IQ motif containing GTPase activating protein 1
chr12_+_79258517 0.072 SYT1
synaptotagmin I
chr2_-_47142939 0.072 MCFD2
multiple coagulation factor deficiency 2
chr16_+_70148213 0.072 PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr5_+_118407067 0.071 NM_005509
DMXL1
Dmx-like 1
chr15_+_40886217 0.071 CASC5
cancer susceptibility candidate 5
chr2_+_65215577 0.070 NM_001193493
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chrX_+_49028183 0.070 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr17_-_76921205 0.070 TIMP2
TIMP metallopeptidase inhibitor 2
chr10_-_108924287 0.070 NM_001013031
NM_001206569
NM_001206570
NM_001206571
NM_001206572
NM_052918
SORCS1





sortilin-related VPS10 domain containing receptor 1





chr4_-_74904329 0.069 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr19_-_38714781 0.069 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chr13_-_96705565 0.068 NM_020121
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2
chr3_-_127541975 0.068 NM_001003794
MGLL
monoglyceride lipase
chr9_+_4985082 0.068 JAK2
Janus kinase 2
chr3_-_52931341 0.068 TMEM110
transmembrane protein 110
chr2_-_224903933 0.067 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr12_+_56660913 0.067 COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr7_-_152373163 0.067 NM_005431
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr22_-_50946020 0.066 LMF2
lipase maturation factor 2
chr20_-_57582152 0.066 CTSZ
cathepsin Z
chr7_+_142985307 0.066 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr2_+_217498205 0.066 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr20_-_57582303 0.066 NM_001336
CTSZ
cathepsin Z
chr11_+_69455978 0.063 CCND1
cyclin D1
chr20_-_50159037 0.063 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_+_8429010 0.063 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr22_+_35777087 0.063 HMOX1
heme oxygenase (decycling) 1
chr8_-_11324184 0.063 NM_053279
FAM167A
family with sequence similarity 167, member A
chr7_-_97601654 0.063


chr1_+_36549714 0.062 TEKT2
tektin 2 (testicular)
chr8_-_13134028 0.062 DLC1
deleted in liver cancer 1
chr4_+_4387982 0.061 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr10_-_13342063 0.061 NM_006214
PHYH
phytanoyl-CoA 2-hydroxylase
chr2_+_217498082 0.061 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr21_+_27012067 0.061 JAM2
junctional adhesion molecule 2
chr14_-_106714594 0.061


chr7_-_73133917 0.061 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr5_+_169010637 0.061 NM_017785
CCDC99
coiled-coil domain containing 99
chr3_-_9811623 0.060 CAMK1
calcium/calmodulin-dependent protein kinase I
chr4_+_39046198 0.060 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr11_+_66278076 0.059 NM_024649
BBS1
Bardet-Biedl syndrome 1
chr7_+_2443164 0.059 NM_001243794
NM_001243795
NM_018641
CHST12


carbohydrate (chondroitin 4) sulfotransferase 12


chr12_+_79258794 0.059 SYT1
synaptotagmin I
chr19_+_50016500 0.058 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr22_-_50946129 0.058 NM_033200
LMF2
lipase maturation factor 2
chr11_+_61595772 0.058 FADS2
fatty acid desaturase 2
chr2_-_120980912 0.058 TMEM185B
transmembrane protein 185B
chr20_+_44098392 0.058 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr3_-_9811583 0.057 CAMK1
calcium/calmodulin-dependent protein kinase I
chr13_-_110959441 0.057 NM_001845
COL4A1
collagen, type IV, alpha 1
chr17_+_39969200 0.057 FKBP10
FK506 binding protein 10, 65 kDa
chr2_-_175869910 0.057 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr22_-_20461785 0.057 NM_015672
RIMBP3
RIMS binding protein 3
chr7_-_23053674 0.057 FAM126A
family with sequence similarity 126, member A
chr8_-_144241918 0.057 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr20_-_4982133 0.056 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr2_-_47142931 0.056 MCFD2
multiple coagulation factor deficiency 2
chr10_+_90639900 0.056 NM_020799
STAMBPL1
STAM binding protein-like 1
chr3_-_66550844 0.056 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr9_+_37650996 0.056 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr4_+_4388804 0.056 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr17_+_18012019 0.055 NM_016239
MYO15A
myosin XVA
chr21_+_45432202 0.055 NM_003274
TRAPPC10
trafficking protein particle complex 10
chr16_+_67312980 0.055 NM_001129728
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr9_-_135230129 0.055 SETX
senataxin
chr17_-_42907606 0.054 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr3_+_52529370 0.054 STAB1
stabilin 1
chr21_+_27011766 0.054 JAM2
junctional adhesion molecule 2
chr13_+_108870713 0.053 NM_032859
ABHD13
abhydrolase domain containing 13
chr8_-_145013628 0.053 NM_201384
PLEC
plectin
chr6_+_39760148 0.053 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr19_-_7939325 0.053 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chr4_+_84457390 0.053 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr4_-_129208928 0.053 PGRMC2
progesterone receptor membrane component 2
chr14_-_52535945 0.052 NM_007361
NID2
nidogen 2 (osteonidogen)
chr10_-_62703822 0.052 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr21_+_27012045 0.051 JAM2
junctional adhesion molecule 2
chr9_-_91793375 0.051 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr22_-_29196452 0.051 XBP1
X-box binding protein 1
chr19_+_11200124 0.051 LDLR
low density lipoprotein receptor
chr9_-_100881515 0.051 TRIM14
tripartite motif containing 14
chr7_+_150755298 0.051 NM_001199692
SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr1_+_110230417 0.051 NM_000561
NM_146421
GSTM1

glutathione S-transferase mu 1

chr11_-_105892908 0.051 NM_032424
KIAA1826
KIAA1826
chr7_-_150020661 0.051 NM_001164458
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr22_+_31003069 0.051 NM_000355
NM_001184726
TCN2

transcobalamin II

chr8_-_125486808 0.050


chrX_-_107019001 0.050 NM_198057
TSC22D3
TSC22 domain family, member 3
chr19_+_50016490 0.050 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_46299585 0.050 CREB3L1
cAMP responsive element binding protein 3-like 1
chr2_-_47142880 0.050 MCFD2
multiple coagulation factor deficiency 2
chr13_+_78271820 0.050 NM_001242868
SLAIN1
SLAIN motif family, member 1
chr14_-_53258329 0.050 NM_198066
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr17_+_39969205 0.050 FKBP10
FK506 binding protein 10, 65 kDa
chr16_+_31494438 0.050 NM_003041
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr17_+_1619816 0.049 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr8_-_144241725 0.049 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr16_-_56459302 0.049 AMFR
autocrine motility factor receptor
chr3_-_49757058 0.049 NM_198722
AMIGO3
adhesion molecule with Ig-like domain 3
chr11_-_61584228 0.049 FADS1
fatty acid desaturase 1
chr19_-_48673559 0.049 NM_000234
LIG1
ligase I, DNA, ATP-dependent
chr19_+_11200146 0.049 LDLR
low density lipoprotein receptor
chr11_+_844111 0.048 TSPAN4
tetraspanin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 8.01e-04 GO:0065007 biological regulation
1.16 7.67e-03 GO:0050789 regulation of biological process
1.15 2.57e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.96e-03 GO:0005622 intracellular
1.13 3.16e-03 GO:0005737 cytoplasm
1.09 4.02e-03 GO:0044424 intracellular part
1.05 2.30e-02 GO:0044464 cell part
1.05 2.36e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.11 8.31e-03 GO:0042393 histone binding