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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for AGCACCA

Z-value: 2.04

Motif logo

miRNA associated with seed AGCACCA

NamemiRBASE accession
MIMAT0000086
MIMAT0000100
MIMAT0000681

Activity profile of AGCACCA motif

Sorted Z-values of AGCACCA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCACCA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_189839046 4.51 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr15_-_48937982 3.65 ENST00000316623.5
FBN1
fibrillin 1
chr7_+_94023873 3.59 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chrX_+_16964794 2.82 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr2_-_238323007 2.61 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr1_-_236228403 2.49 ENST00000366595.3
NID1
nidogen 1
chr1_-_72748417 2.47 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr3_+_99357319 2.44 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr5_-_111093406 2.19 ENST00000379671.3
NREP
neuronal regeneration related protein
chr17_-_48278983 2.07 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr5_-_149535421 2.04 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_-_190044480 1.98 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr16_+_55512742 1.97 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr4_+_124320665 1.86 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr6_-_88876058 1.64 ENST00000369501.2
CNR1
cannabinoid receptor 1 (brain)
chr2_+_148778570 1.56 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr22_-_44708731 1.54 ENST00000381176.4
KIAA1644
KIAA1644
chr5_-_121413974 1.52 ENST00000231004.4
LOX
lysyl oxidase
chr21_-_39288743 1.45 ENST00000609713.1
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr11_-_82782861 1.43 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr8_-_120651020 1.43 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_+_56411131 1.42 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chrX_+_9754461 1.38 ENST00000380913.3
SHROOM2
shroom family member 2
chr20_+_33292068 1.38 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr9_+_101705893 1.38 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr3_-_120170052 1.35 ENST00000295633.3
FSTL1
follistatin-like 1
chr5_-_137368708 1.31 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr3_-_114790179 1.26 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_201617450 1.23 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1
neuron navigator 1
chr5_+_67511524 1.18 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_3447967 1.16 ENST00000294599.4
MEGF6
multiple EGF-like-domains 6
chr1_-_17304771 1.14 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr1_+_213123915 1.13 ENST00000366968.4
ENST00000490792.1
VASH2
vasohibin 2
chr5_-_146833485 1.12 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr1_-_46598284 1.06 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_-_52441713 1.02 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr8_-_93115445 1.01 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_103031758 1.00 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr4_-_157892498 0.96 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr8_-_122653630 0.96 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr17_+_47074758 0.95 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr2_-_180129484 0.91 ENST00000428443.3
SESTD1
SEC14 and spectrin domains 1
chrX_-_71351678 0.91 ENST00000609883.1
ENST00000545866.1
RGAG4
retrotransposon gag domain containing 4
chr16_+_88493879 0.91 ENST00000565624.1
ENST00000437464.1
ZNF469
zinc finger protein 469
chr14_-_90085458 0.88 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr6_+_30524663 0.87 ENST00000376560.3
PRR3
proline rich 3
chr3_+_42695176 0.85 ENST00000232974.6
ENST00000457842.3
ZBTB47
zinc finger and BTB domain containing 47
chr13_-_67804445 0.84 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr5_+_110559784 0.84 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr10_+_105036909 0.82 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chrX_-_106959631 0.81 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr6_+_108881012 0.80 ENST00000343882.6
FOXO3
forkhead box O3
chr12_-_31744031 0.77 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr4_-_142053952 0.73 ENST00000515673.2
RNF150
ring finger protein 150
chr17_+_57408994 0.72 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr14_+_23067146 0.71 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr17_-_28618948 0.70 ENST00000261714.6
BLMH
bleomycin hydrolase
chr2_+_54951679 0.70 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr17_-_56032684 0.69 ENST00000577830.1
CUEDC1
CUE domain containing 1
chr5_-_90679145 0.69 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chrX_+_107683096 0.69 ENST00000328300.6
ENST00000361603.2
COL4A5
collagen, type IV, alpha 5
chr8_+_38614807 0.68 ENST00000330691.6
ENST00000348567.4
TACC1
transforming, acidic coiled-coil containing protein 1
chr7_+_102073966 0.67 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI2
ORAI calcium release-activated calcium modulator 2
chr16_+_4364762 0.67 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr3_-_179169330 0.66 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr5_-_171711061 0.65 ENST00000393792.2
UBTD2
ubiquitin domain containing 2
chr1_-_156828810 0.65 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr2_-_202316260 0.65 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr5_+_153825510 0.65 ENST00000297109.6
SAP30L
SAP30-like
chr17_+_58677539 0.65 ENST00000305921.3
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr3_-_48632593 0.64 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr19_-_10121144 0.64 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr10_+_70320413 0.64 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr21_-_28338732 0.62 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_-_107681633 0.62 ENST00000394872.2
ENST00000334504.7
COL4A6
collagen, type IV, alpha 6
chr15_-_68724490 0.61 ENST00000315757.7
ENST00000423218.2
ITGA11
integrin, alpha 11
chr6_+_39760783 0.60 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr4_-_17783135 0.60 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr6_-_24911195 0.59 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr5_+_157170703 0.59 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr19_+_48216600 0.58 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chr20_-_45035223 0.58 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2
engulfment and cell motility 2
chr6_-_111804393 0.57 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_+_72937182 0.57 ENST00000389617.4
GXYLT2
glucoside xylosyltransferase 2
chr2_+_88047606 0.57 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr22_+_42470244 0.55 ENST00000321753.3
FAM109B
family with sequence similarity 109, member B
chr17_-_15165854 0.55 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr12_-_81331697 0.55 ENST00000552864.1
LIN7A
lin-7 homolog A (C. elegans)
chr10_+_104535994 0.55 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr17_+_14204389 0.54 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_-_3227877 0.54 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr16_-_77468945 0.54 ENST00000282849.5
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr3_+_137906109 0.54 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr3_+_191046810 0.54 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr9_+_135037334 0.54 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr20_+_34700333 0.53 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_-_62601218 0.53 ENST00000369888.1
ZNF512B
zinc finger protein 512B
chr15_-_79103757 0.53 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr12_+_60083118 0.52 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr5_+_134181625 0.52 ENST00000394976.3
C5orf24
chromosome 5 open reading frame 24
chr5_-_107006596 0.52 ENST00000333274.6
EFNA5
ephrin-A5
chr1_+_178062855 0.51 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr15_-_82338460 0.51 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr8_-_57123815 0.51 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr5_-_122372354 0.51 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr10_+_120789223 0.51 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr3_-_183543301 0.51 ENST00000318631.3
ENST00000431348.1
MAP6D1
MAP6 domain containing 1
chr11_+_117049445 0.51 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chr7_+_106809406 0.50 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chrX_-_64196307 0.50 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr11_-_66336060 0.49 ENST00000310325.5
CTSF
cathepsin F
chr6_-_28220002 0.48 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr2_+_12857015 0.48 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr3_+_197687071 0.48 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
LMLN
leishmanolysin-like (metallopeptidase M8 family)
chr22_-_44894178 0.47 ENST00000341255.3
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr8_-_23712312 0.47 ENST00000290271.2
STC1
stanniocalcin 1
chr2_-_227664474 0.46 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr10_+_1095416 0.45 ENST00000358220.1
WDR37
WD repeat domain 37
chr16_+_69599861 0.45 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_33722080 0.45 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr5_-_78281603 0.44 ENST00000264914.4
ARSB
arylsulfatase B
chr14_+_55034599 0.44 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr11_-_57283159 0.44 ENST00000533263.1
ENST00000278426.3
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr7_-_28220354 0.44 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr14_-_80677970 0.43 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr10_-_128077024 0.43 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12
ADAM metallopeptidase domain 12
chr13_-_53024725 0.43 ENST00000378060.4
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr15_-_61521495 0.43 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr7_+_17338239 0.42 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr7_+_138145076 0.42 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr14_-_53417732 0.42 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr11_-_117186946 0.42 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr3_+_43732362 0.42 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr1_-_225840747 0.42 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr3_-_164913777 0.42 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr5_-_157002775 0.41 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr7_+_135347215 0.41 ENST00000507606.1
C7orf73
chromosome 7 open reading frame 73
chr8_-_95961578 0.41 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr1_+_185703513 0.41 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr2_-_119605253 0.41 ENST00000295206.6
EN1
engrailed homeobox 1
chr8_-_82024290 0.41 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr15_+_42867857 0.41 ENST00000290607.7
STARD9
StAR-related lipid transfer (START) domain containing 9
chr8_+_26435359 0.40 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr16_-_46865047 0.40 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr17_-_40575535 0.40 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr10_+_115438920 0.39 ENST00000429617.1
ENST00000369331.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr10_-_32636106 0.39 ENST00000263062.8
ENST00000319778.6
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr9_+_137533615 0.39 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr17_+_21279509 0.38 ENST00000583088.1
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr7_+_73442102 0.38 ENST00000445912.1
ENST00000252034.7
ELN
elastin
chr4_-_140098339 0.38 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr5_+_149887672 0.38 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_64211112 0.37 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr5_+_112043186 0.37 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
APC
adenomatous polyposis coli
chr9_-_110251836 0.37 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr11_-_61348576 0.37 ENST00000263846.4
SYT7
synaptotagmin VII
chr9_+_35161998 0.36 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr7_+_3340989 0.36 ENST00000404826.2
ENST00000389531.3
SDK1
sidekick cell adhesion molecule 1
chr11_+_35965531 0.36 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr14_-_35182994 0.35 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr17_-_40540377 0.35 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr2_+_109204909 0.35 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr20_+_30555805 0.35 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr7_-_112579869 0.35 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr10_-_50747064 0.34 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
ERCC6
PGBD3
ERCC6-PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr10_-_62704005 0.34 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr2_+_228029281 0.34 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr20_-_5591626 0.34 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr12_+_32655048 0.34 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_133464151 0.33 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr15_+_41952591 0.33 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr1_-_27816556 0.33 ENST00000536657.1
WASF2
WAS protein family, member 2
chr20_+_46130601 0.33 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr14_+_74111578 0.33 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr1_-_155881156 0.32 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr1_+_218519577 0.32 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr1_+_2160134 0.32 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr17_-_1465924 0.31 ENST00000573231.1
ENST00000576722.1
ENST00000576761.1
ENST00000576010.2
ENST00000313486.7
ENST00000539476.1
PITPNA
phosphatidylinositol transfer protein, alpha
chr3_-_72496035 0.31 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr11_-_8680383 0.31 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr2_-_61697862 0.31 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr1_-_166028709 0.30 ENST00000595430.1
AL626787.1
AL626787.1
chr8_+_134203273 0.30 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr5_+_154238096 0.30 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr20_-_39928705 0.30 ENST00000436099.2
ENST00000309060.3
ENST00000373261.1
ENST00000436440.2
ENST00000540170.1
ENST00000557816.1
ENST00000560361.1
ZHX3
zinc fingers and homeoboxes 3
chr1_+_31769836 0.30 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17
zinc finger, CCHC domain containing 17
chr12_+_94542459 0.30 ENST00000258526.4
PLXNC1
plexin C1
chr20_+_56964169 0.29 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr12_+_9067327 0.29 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr10_-_30024716 0.29 ENST00000375398.2
ENST00000375400.3
SVIL
supervillin
chr14_-_77923897 0.29 ENST00000343765.2
ENST00000327028.4
ENST00000556412.1
ENST00000557466.1
ENST00000448935.2
ENST00000553888.1
ENST00000557658.1
VIPAS39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr11_+_120894781 0.29 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL
tubulin folding cofactor E-like
chr17_+_45810594 0.29 ENST00000177694.1
TBX21
T-box 21
chr17_-_1532106 0.29 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr19_-_36545649 0.29 ENST00000292894.1
THAP8
THAP domain containing 8
chr3_+_15247686 0.28 ENST00000253693.2
CAPN7
calpain 7
chr2_-_1748214 0.28 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr4_-_85887503 0.28 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3
WD repeat and FYVE domain containing 3
chr15_-_71055878 0.28 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr20_+_30865429 0.28 ENST00000375712.3
KIF3B
kinesin family member 3B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0044691 tooth eruption(GO:0044691)
0.8 2.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.9 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.6 3.7 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.5 0.5 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.5 2.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.5 4.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 1.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 1.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 2.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 0.8 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.3 1.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 3.6 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.7 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 0.4 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 0.5 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.2 0.7 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.2 2.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.4 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.7 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 1.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.4 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.4 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.4 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.7 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0060913 cardiac cell fate determination(GO:0060913)
0.1 0.1 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.1 1.5 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 1.6 GO:0045176 apical protein localization(GO:0045176)
0.1 0.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 7.7 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.5 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.8 GO:0030900 forebrain development(GO:0030900)
0.1 0.4 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 1.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 2.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.8 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.1 0.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.2 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.9 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.5 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 1.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0045925 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0 0.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 1.1 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 1.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 3.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 1.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.3 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.3 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005588 collagen type V trimer(GO:0005588)
0.8 9.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 5.7 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.3 1.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 3.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 0.6 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.2 4.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.2 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.6 GO:0005683 U7 snRNP(GO:0005683)
0.1 2.6 GO:0005605 basal lamina(GO:0005605)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.7 GO:0010369 chromocenter(GO:0010369)
0.1 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.7 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 1.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 2.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.5 3.7 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 1.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 1.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 1.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 2.5 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 2.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2 0.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 0.5 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.6 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.5 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.1 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.1 0.7 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.2 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 5.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.6 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.0 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 19.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 14.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 4.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing