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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ARID3A

Z-value: 1.45

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Transcription factors associated with ARID3A

Gene Symbol Gene ID Gene Info
ARID3A
ENSG00000116017.6 ARID3A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID3Ahg19_v2_chr19_+_926000_926046-0.849.1e-03Click!

Activity profile of ARID3A motif

Sorted Z-values of ARID3A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID3A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_61554932 3.19 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr1_+_77333117 1.96 ENST00000477717.1
 ST6GALNAC5
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr2_-_165424973 1.82 ENST00000543549.1
 GRB14
 growth factor receptor-bound protein 14
chr17_-_3599696 1.62 ENST00000225328.5
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599327 1.60 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599492 1.56 ENST00000435558.1
ENST00000345901.3
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr5_+_140220769 1.35 ENST00000531613.1
ENST00000378123.3
 PCDHA8
 protocadherin alpha 8
chr6_-_136847099 1.27 ENST00000438100.2
 MAP7
 microtubule-associated protein 7
chr12_-_28125638 1.19 ENST00000545234.1
 PTHLH
 parathyroid hormone-like hormone
chr16_+_76587314 1.17 ENST00000563764.1
 RP11-58C22.1
 Uncharacterized protein
chr8_+_18248786 1.07 ENST00000520116.1
 NAT2
 N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr8_+_18248755 1.06 ENST00000286479.3
 NAT2
 N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr20_+_58179582 1.06 ENST00000371015.1
ENST00000395639.4
 PHACTR3
 phosphatase and actin regulator 3
chr1_-_207206092 0.96 ENST00000359470.5
ENST00000461135.2
 C1orf116
 chromosome 1 open reading frame 116
chr11_+_67351213 0.85 ENST00000398603.1
 GSTP1
 glutathione S-transferase pi 1
chrX_-_114252193 0.85 ENST00000243213.1
 IL13RA2
 interleukin 13 receptor, alpha 2
chr6_+_47624172 0.83 ENST00000507065.1
ENST00000296862.1
 GPR111
 G protein-coupled receptor 111
chr11_+_67351019 0.78 ENST00000398606.3
 GSTP1
 glutathione S-transferase pi 1
chr7_-_139763521 0.76 ENST00000263549.3
 PARP12
 poly (ADP-ribose) polymerase family, member 12
chr7_+_107224364 0.73 ENST00000491150.1
 BCAP29
 B-cell receptor-associated protein 29
chr17_-_56494713 0.71 ENST00000407977.2
 RNF43
 ring finger protein 43
chr17_-_56494882 0.71 ENST00000584437.1
 RNF43
 ring finger protein 43
chr17_-_56494908 0.71 ENST00000577716.1
 RNF43
 ring finger protein 43
chr12_-_95044309 0.68 ENST00000261226.4
 TMCC3
 transmembrane and coiled-coil domain family 3
chr3_+_36421826 0.68 ENST00000273183.3
 STAC
 SH3 and cysteine rich domain
chr4_+_100737954 0.67 ENST00000296414.7
ENST00000512369.1
 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
chr19_-_55652290 0.66 ENST00000589745.1
 TNNT1
 troponin T type 1 (skeletal, slow)
chr11_+_18154059 0.64 ENST00000531264.1
 MRGPRX3
 MAS-related GPR, member X3
chr2_+_106468204 0.61 ENST00000425756.1
ENST00000393349.2
 NCK2
 NCK adaptor protein 2
chr7_-_22539771 0.60 ENST00000406890.2
ENST00000424363.1
 STEAP1B
 STEAP family member 1B
chr8_+_32579341 0.59 ENST00000519240.1
ENST00000539990.1
 NRG1
 neuregulin 1
chrX_-_117119243 0.58 ENST00000539496.1
ENST00000469946.1
 KLHL13
 kelch-like family member 13
chr5_+_140180635 0.57 ENST00000522353.2
ENST00000532566.2
 PCDHA3
 protocadherin alpha 3
chr4_-_76957214 0.55 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chr1_+_207943667 0.53 ENST00000462968.2
 CD46
 CD46 molecule, complement regulatory protein
chr19_-_48614063 0.52 ENST00000599921.1
ENST00000599111.1
 PLA2G4C
 phospholipase A2, group IVC (cytosolic, calcium-independent)
chr19_-_48614033 0.51 ENST00000354276.3
 PLA2G4C
 phospholipase A2, group IVC (cytosolic, calcium-independent)
chr7_-_38305279 0.51 ENST00000443402.2
 TRGC1
 T cell receptor gamma constant 1
chr16_+_19421803 0.47 ENST00000541464.1
 TMC5
 transmembrane channel-like 5
chr6_+_121756809 0.46 ENST00000282561.3
 GJA1
 gap junction protein, alpha 1, 43kDa
chr21_+_34442439 0.46 ENST00000382348.1
ENST00000333063.5
 OLIG1
 oligodendrocyte transcription factor 1
chr12_+_113344582 0.45 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_80994619 0.44 ENST00000404191.1
 ANTXR2
 anthrax toxin receptor 2
chr6_-_116381918 0.43 ENST00000606080.1
 FRK
 fyn-related kinase
chr8_+_104892639 0.43 ENST00000436393.2
 RIMS2
 regulating synaptic membrane exocytosis 2
chr4_-_80994210 0.43 ENST00000403729.2
 ANTXR2
 anthrax toxin receptor 2
chr7_+_89783689 0.41 ENST00000297205.2
 STEAP1
 six transmembrane epithelial antigen of the prostate 1
chr2_+_191002486 0.40 ENST00000396974.2
 C2orf88
 chromosome 2 open reading frame 88
chr4_+_74301880 0.40 ENST00000395792.2
ENST00000226359.2
 AFP
 alpha-fetoprotein
chr1_-_100231349 0.39 ENST00000287474.5
ENST00000414213.1
 FRRS1
 ferric-chelate reductase 1
chr3_+_118892362 0.39 ENST00000497685.1
ENST00000264234.3
 UPK1B
 uroplakin 1B
chr17_-_15466742 0.38 ENST00000584811.1
ENST00000419890.2
 TVP23C
 trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr12_-_39734783 0.38 ENST00000552961.1
 KIF21A
 kinesin family member 21A
chr4_+_71200681 0.38 ENST00000273936.5
 CABS1
 calcium-binding protein, spermatid-specific 1
chr2_-_130031335 0.38 ENST00000375987.3
 AC079586.1
 AC079586.1
chr14_+_39734482 0.37 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
 CTAGE5
 CTAGE family, member 5
chr17_+_7531281 0.36 ENST00000575729.1
ENST00000340624.5
 SHBG
 sex hormone-binding globulin
chr4_-_80994471 0.36 ENST00000295465.4
 ANTXR2
 anthrax toxin receptor 2
chr1_-_235098935 0.35 ENST00000423175.1
 RP11-443B7.1
 RP11-443B7.1
chr2_-_160473114 0.35 ENST00000392783.2
 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
chr19_+_9296279 0.35 ENST00000344248.2
 OR7D2
 olfactory receptor, family 7, subfamily D, member 2
chr4_-_170948361 0.34 ENST00000393702.3
 MFAP3L
 microfibrillar-associated protein 3-like
chr11_+_112046190 0.34 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
 BCO2
 beta-carotene oxygenase 2
chr4_+_74606223 0.34 ENST00000307407.3
ENST00000401931.1
 IL8
 interleukin 8
chr15_+_75491213 0.32 ENST00000360639.2
 C15orf39
 chromosome 15 open reading frame 39
chr11_+_118175132 0.31 ENST00000361763.4
 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
chr17_+_18684563 0.30 ENST00000476139.1
 TVP23B
 trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr16_+_19422035 0.30 ENST00000381414.4
ENST00000396229.2
 TMC5
 transmembrane channel-like 5
chr9_-_21351377 0.29 ENST00000380210.1
 IFNA6
 interferon, alpha 6
chr11_+_45825616 0.29 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
 SLC35C1
 solute carrier family 35 (GDP-fucose transporter), member C1
chr6_-_46703430 0.28 ENST00000537365.1
 PLA2G7
 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_-_29641104 0.28 ENST00000577894.1
ENST00000330927.4
 EVI2B
 ecotropic viral integration site 2B
chr17_-_18430160 0.27 ENST00000392176.3
 FAM106A
 family with sequence similarity 106, member A
chr16_+_81812863 0.27 ENST00000359376.3
 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr10_+_5238793 0.27 ENST00000263126.1
 AKR1C4
 aldo-keto reductase family 1, member C4
chr7_-_100253993 0.27 ENST00000461605.1
ENST00000160382.5
 ACTL6B
 actin-like 6B
chr11_+_35201826 0.26 ENST00000531873.1
 CD44
 CD44 molecule (Indian blood group)
chr18_+_61144160 0.26 ENST00000489441.1
ENST00000424602.1
 SERPINB5
 serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_-_139396853 0.26 ENST00000406164.1
ENST00000406824.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chr7_-_38289173 0.26 ENST00000436911.2
 TRGC2
 T cell receptor gamma constant 2
chr10_+_26727125 0.26 ENST00000376236.4
 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_-_92855762 0.26 ENST00000453812.2
ENST00000394468.2
 HEPACAM2
 HEPACAM family member 2
chr6_+_111303218 0.25 ENST00000441448.2
 RPF2
 ribosome production factor 2 homolog (S. cerevisiae)
chr3_+_43328004 0.25 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
 SNRK
 SNF related kinase
chr22_+_18721427 0.25 ENST00000342888.3
 AC008132.1
 Uncharacterized protein
chr12_+_113682066 0.24 ENST00000392569.4
ENST00000552542.1
 TPCN1
 two pore segment channel 1
chr17_-_41050716 0.24 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
 LINC00671
 long intergenic non-protein coding RNA 671
chr7_+_76090993 0.23 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
 DTX2
 deltex homolog 2 (Drosophila)
chr8_+_86099884 0.23 ENST00000517476.1
ENST00000521429.1
 E2F5
 E2F transcription factor 5, p130-binding
chr9_-_21385396 0.23 ENST00000380206.2
 IFNA2
 interferon, alpha 2
chr12_+_122688090 0.23 ENST00000324189.4
ENST00000546192.1
 B3GNT4
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr3_-_139396801 0.23 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chr8_-_62559366 0.23 ENST00000522919.1
 ASPH
 aspartate beta-hydroxylase
chr1_-_39395165 0.23 ENST00000372985.3
 RHBDL2
 rhomboid, veinlet-like 2 (Drosophila)
chr19_+_11200038 0.23 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
 LDLR
 low density lipoprotein receptor
chr11_-_5255861 0.22 ENST00000380299.3
 HBD
 hemoglobin, delta
chr1_+_196743912 0.22 ENST00000367425.4
 CFHR3
 complement factor H-related 3
chr11_+_112047087 0.22 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
 BCO2
 beta-carotene oxygenase 2
chr6_-_29324054 0.22 ENST00000543825.1
 OR5V1
 olfactory receptor, family 5, subfamily V, member 1
chr5_+_126988732 0.21 ENST00000395322.3
 CTXN3
 cortexin 3
chr8_-_87242589 0.21 ENST00000419776.2
ENST00000297524.3
 SLC7A13
 solute carrier family 7 (anionic amino acid transporter), member 13
chr1_-_235098861 0.21 ENST00000458044.1
 RP11-443B7.1
 RP11-443B7.1
chr14_+_97263641 0.21 ENST00000216639.3
 VRK1
 vaccinia related kinase 1
chr12_+_69186125 0.21 ENST00000399333.3
 AC124890.1
 HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr12_+_119772502 0.21 ENST00000536742.1
ENST00000327554.2
 CCDC60
 coiled-coil domain containing 60
chr18_-_13915530 0.21 ENST00000327606.3
 MC2R
 melanocortin 2 receptor (adrenocorticotropic hormone)
chr22_-_40289759 0.21 ENST00000325157.6
 ENTHD1
 ENTH domain containing 1
chr1_+_196743943 0.20 ENST00000471440.2
ENST00000391985.3
 CFHR3
 complement factor H-related 3
chr3_-_191000172 0.20 ENST00000427544.2
 UTS2B
 urotensin 2B
chr6_+_24403144 0.20 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
 MRS2
 MRS2 magnesium transporter
chr6_+_31105426 0.19 ENST00000547221.1
 PSORS1C1
 psoriasis susceptibility 1 candidate 1
chr2_+_109335929 0.19 ENST00000283195.6
 RANBP2
 RAN binding protein 2
chr4_-_57844989 0.19 ENST00000264230.4
 NOA1
 nitric oxide associated 1
chr1_+_73771844 0.19 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
 RP4-598G3.1
 RP4-598G3.1
chr14_-_53162361 0.19 ENST00000395686.3
 ERO1L
 ERO1-like (S. cerevisiae)
chr3_+_142442841 0.18 ENST00000476941.1
ENST00000273482.6
 TRPC1
 transient receptor potential cation channel, subfamily C, member 1
chr4_-_169239921 0.18 ENST00000514995.1
ENST00000393743.3
 DDX60
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr4_-_68749745 0.18 ENST00000283916.6
 TMPRSS11D
 transmembrane protease, serine 11D
chr15_-_49103235 0.18 ENST00000380950.2
 CEP152
 centrosomal protein 152kDa
chr19_+_45542295 0.18 ENST00000221455.3
ENST00000391953.4
ENST00000588936.1
 CLASRP
 CLK4-associating serine/arginine rich protein
chr6_+_26087509 0.18 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
 HFE
 hemochromatosis
chr12_-_11287243 0.17 ENST00000539585.1
 TAS2R30
 taste receptor, type 2, member 30
chr12_-_120765565 0.17 ENST00000423423.3
ENST00000308366.4
 PLA2G1B
 phospholipase A2, group IB (pancreas)
chrX_+_139791917 0.17 ENST00000607004.1
ENST00000370535.3
 LINC00632
 long intergenic non-protein coding RNA 632
chr12_-_4488872 0.17 ENST00000237837.1
 FGF23
 fibroblast growth factor 23
chr19_+_11670245 0.17 ENST00000585493.1
 ZNF627
 zinc finger protein 627
chr8_-_102218292 0.17 ENST00000518336.1
ENST00000520454.1
 ZNF706
 zinc finger protein 706
chr12_-_113772835 0.17 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
 SLC8B1
 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr16_+_30935418 0.17 ENST00000338343.4
 FBXL19
 F-box and leucine-rich repeat protein 19
chr14_+_70918874 0.17 ENST00000603540.1
 ADAM21
 ADAM metallopeptidase domain 21
chr2_-_219031709 0.17 ENST00000295683.2
 CXCR1
 chemokine (C-X-C motif) receptor 1
chr4_+_15341442 0.16 ENST00000397700.2
ENST00000295297.4
 C1QTNF7
 C1q and tumor necrosis factor related protein 7
chr16_+_56970567 0.16 ENST00000563911.1
 HERPUD1
 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_+_32832134 0.16 ENST00000452533.2
 DNM1L
 dynamin 1-like
chr9_-_19786926 0.16 ENST00000341998.2
ENST00000286344.3
 SLC24A2
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chrX_+_83116142 0.15 ENST00000329312.4
 CYLC1
 cylicin, basic protein of sperm head cytoskeleton 1
chrX_-_2882296 0.15 ENST00000438544.1
ENST00000381134.3
ENST00000545496.1
 ARSE
 arylsulfatase E (chondrodysplasia punctata 1)
chr4_-_96470108 0.15 ENST00000513796.1
 UNC5C
 unc-5 homolog C (C. elegans)
chr12_-_71182695 0.15 ENST00000342084.4
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr4_+_159131630 0.15 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
 TMEM144
 transmembrane protein 144
chr10_-_11574274 0.15 ENST00000277575.5
 USP6NL
 USP6 N-terminal like
chr4_-_100356291 0.14 ENST00000476959.1
ENST00000482593.1
 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_55230165 0.14 ENST00000371279.3
 PARS2
 prolyl-tRNA synthetase 2, mitochondrial (putative)
chr16_-_84220604 0.14 ENST00000567759.1
 TAF1C
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr14_+_22694606 0.14 ENST00000390463.3
 TRAV36DV7
 T cell receptor alpha variable 36/delta variable 7
chr12_+_32832203 0.14 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
 DNM1L
 dynamin 1-like
chr5_-_75013193 0.14 ENST00000514838.2
ENST00000506164.1
ENST00000502826.1
ENST00000503835.1
ENST00000428202.2
ENST00000380475.2
 POC5
 POC5 centriolar protein
chr4_-_69434245 0.14 ENST00000317746.2
 UGT2B17
 UDP glucuronosyltransferase 2 family, polypeptide B17
chr7_+_115862858 0.14 ENST00000393481.2
 TES
 testis derived transcript (3 LIM domains)
chr4_-_110723194 0.14 ENST00000394635.3
 CFI
 complement factor I
chr3_-_139396787 0.14 ENST00000296202.7
ENST00000509291.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chrX_+_21857717 0.14 ENST00000379484.5
 MBTPS2
 membrane-bound transcription factor peptidase, site 2
chr11_-_5207612 0.13 ENST00000380367.1
 OR52A1
 olfactory receptor, family 52, subfamily A, member 1
chr16_-_11375179 0.13 ENST00000312511.3
 PRM1
 protamine 1
chr6_+_26087646 0.13 ENST00000309234.6
 HFE
 hemochromatosis
chr1_-_205391178 0.13 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
 LEMD1
 LEM domain containing 1
chr6_-_100016678 0.13 ENST00000523799.1
ENST00000520429.1
 CCNC
 cyclin C
chr11_-_5345582 0.13 ENST00000328813.2
 OR51B2
 olfactory receptor, family 51, subfamily B, member 2
chrX_+_134975858 0.13 ENST00000537770.1
 SAGE1
 sarcoma antigen 1
chrX_+_134975753 0.13 ENST00000535938.1
 SAGE1
 sarcoma antigen 1
chr4_+_57845043 0.13 ENST00000433463.1
ENST00000314595.5
 POLR2B
 polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr18_-_64271363 0.12 ENST00000262150.2
 CDH19
 cadherin 19, type 2
chr6_-_100016527 0.12 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
 CCNC
 cyclin C
chr19_-_55458860 0.12 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
 NLRP7
 NLR family, pyrin domain containing 7
chr8_-_59412717 0.12 ENST00000301645.3
 CYP7A1
 cytochrome P450, family 7, subfamily A, polypeptide 1
chr3_+_57875738 0.12 ENST00000417128.1
ENST00000438794.1
 SLMAP
 sarcolemma associated protein
chr18_-_19994830 0.12 ENST00000525417.1
 CTAGE1
 cutaneous T-cell lymphoma-associated antigen 1
chr13_-_102068769 0.12 ENST00000376196.3
 NALCN
 sodium leak channel, non-selective
chr16_+_84801852 0.12 ENST00000569925.1
ENST00000567526.1
 USP10
 ubiquitin specific peptidase 10
chr10_+_62538089 0.12 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
 CDK1
 cyclin-dependent kinase 1
chr15_-_45670924 0.12 ENST00000396659.3
 GATM
 glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_-_110723335 0.12 ENST00000394634.2
 CFI
 complement factor I
chr9_-_86571628 0.11 ENST00000376344.3
 C9orf64
 chromosome 9 open reading frame 64
chr10_+_7745232 0.11 ENST00000358415.4
 ITIH2
 inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_118305435 0.11 ENST00000369221.2
 PNLIP
 pancreatic lipase
chr1_+_53308398 0.11 ENST00000371528.1
 ZYG11A
 zyg-11 family member A, cell cycle regulator
chr10_+_7745303 0.11 ENST00000429820.1
ENST00000379587.4
 ITIH2
 inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_102413726 0.11 ENST00000350878.4
 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
chr16_+_30034655 0.11 ENST00000300575.2
 C16orf92
 chromosome 16 open reading frame 92
chr4_+_5527117 0.11 ENST00000505296.1
 C4orf6
 chromosome 4 open reading frame 6
chr17_-_27333311 0.11 ENST00000317338.12
ENST00000585644.1
 SEZ6
 seizure related 6 homolog (mouse)
chr9_-_27005686 0.11 ENST00000380055.5
 LRRC19
 leucine rich repeat containing 19
chr16_-_84220633 0.11 ENST00000566732.1
ENST00000561955.1
ENST00000564454.1
ENST00000341690.6
ENST00000541676.1
ENST00000570117.1
ENST00000564345.1
 TAF1C
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr1_-_31661000 0.11 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
 NKAIN1
 Na+/K+ transporting ATPase interacting 1
chr17_-_15466850 0.11 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
 TVP23C
TVP23C-CDRT4
 trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr3_+_169629354 0.10 ENST00000428432.2
ENST00000335556.3
 SAMD7
 sterile alpha motif domain containing 7
chr11_+_22688150 0.10 ENST00000454584.2
 GAS2
 growth arrest-specific 2
chr4_-_185275104 0.10 ENST00000317596.3
 RP11-290F5.2
 RP11-290F5.2
chrY_-_20935572 0.10 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
 HSFY2
 heat shock transcription factor, Y linked 2
chr4_+_5526883 0.10 ENST00000195455.2
 C4orf6
 chromosome 4 open reading frame 6
chr7_-_33080506 0.10 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
 NT5C3A
 5'-nucleotidase, cytosolic IIIA
chr4_+_70796784 0.10 ENST00000246891.4
ENST00000444405.3
 CSN1S1
 casein alpha s1
chr2_-_208994548 0.10 ENST00000282141.3
 CRYGC
 crystallin, gamma C
chrY_+_20708557 0.10 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
 HSFY1
 heat shock transcription factor, Y-linked 1
chr15_-_34880646 0.10 ENST00000543376.1
 GOLGA8A
 golgin A8 family, member A
chr2_+_90121477 0.09 ENST00000483379.1
 IGKV1D-17
 immunoglobulin kappa variable 1D-17
chr12_+_96883347 0.09 ENST00000524981.4
ENST00000298953.3
 C12orf55
 chromosome 12 open reading frame 55
chrX_+_48242863 0.09 ENST00000376886.2
ENST00000375517.3
 SSX4
 synovial sarcoma, X breakpoint 4
chr9_-_139343294 0.09 ENST00000313084.5
 SEC16A
 SEC16 homolog A (S. cerevisiae)
chr5_+_140227357 0.09 ENST00000378122.3
 PCDHA9
 protocadherin alpha 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 1.6 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.6 GO:0042214 terpene metabolic process(GO:0042214)
0.2 0.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 1.0 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 4.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 1.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 0.3 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.1 0.8 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 3.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.5 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 2.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.3 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.3 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.3 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 1.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:0046469 platelet activating factor metabolic process(GO:0046469)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.5 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 2.3 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 1.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0030099 myeloid cell differentiation(GO:0030099)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.2 4.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.2 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0005712 chiasma(GO:0005712)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 4.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 1.6 GO:0070026 nitric oxide binding(GO:0070026)
0.3 2.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.7 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 2.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.0 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.4 PID INSULIN PATHWAY Insulin Pathway
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.4 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha