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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 1.55

Motif logo

Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
ENSG00000180828.1 BHLHE22
ENSG00000180535.3 BHLHA15
ENSG00000125533.4 BHLHE23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHE23hg19_v2_chr20_-_61638313_61638387-0.724.5e-02Click!
BHLHE22hg19_v2_chr8_+_65492756_65492814-0.502.1e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_111312622 3.52 ENST00000395634.3
NREP
neuronal regeneration related protein
chr2_-_188378368 2.31 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr9_+_18474098 1.25 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr12_-_91573132 1.03 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr1_+_170633047 1.01 ENST00000239461.6
ENST00000497230.2
PRRX1
paired related homeobox 1
chr12_-_91573316 0.98 ENST00000393155.1
DCN
decorin
chr3_-_114477962 0.92 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_114477787 0.90 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr13_+_49551020 0.81 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr4_+_160188889 0.80 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_163099885 0.69 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr4_+_55095264 0.51 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chrX_+_70798261 0.51 ENST00000373696.3
ACRC
acidic repeat containing
chr1_-_186344802 0.51 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr15_-_98417780 0.47 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr12_-_108714412 0.47 ENST00000412676.1
ENST00000550573.1
CMKLR1
chemokine-like receptor 1
chr2_+_210444748 0.46 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr10_-_31288398 0.46 ENST00000538351.2
ZNF438
zinc finger protein 438
chr1_+_104293028 0.44 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr19_+_18208603 0.41 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr6_+_69942298 0.41 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr3_-_178984759 0.40 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr15_-_55700216 0.38 ENST00000569205.1
CCPG1
cell cycle progression 1
chr4_-_159094194 0.38 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr3_-_18480260 0.35 ENST00000454909.2
SATB1
SATB homeobox 1
chr15_-_55700522 0.34 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr7_-_38403077 0.33 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr5_-_137674000 0.33 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr6_+_73076432 0.32 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_163100045 0.32 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr2_-_182545603 0.31 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr3_-_121379739 0.31 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_61330931 0.30 ENST00000371191.1
NFIA
nuclear factor I/A
chr1_+_95975672 0.29 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr19_-_37019562 0.29 ENST00000523638.1
ZNF260
zinc finger protein 260
chr16_-_4896205 0.29 ENST00000589389.1
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr15_-_63448973 0.28 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr7_+_148287657 0.26 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr5_+_173316341 0.25 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr16_+_21716284 0.25 ENST00000388957.3
OTOA
otoancorin
chr9_+_18474163 0.25 ENST00000380566.4
ADAMTSL1
ADAMTS-like 1
chr12_-_91573249 0.23 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr5_+_135496675 0.23 ENST00000507637.1
SMAD5
SMAD family member 5
chr3_+_185300391 0.22 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr15_-_55700457 0.19 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr6_-_169364429 0.19 ENST00000444586.1
RP3-495K2.3
RP3-495K2.3
chr10_+_5135981 0.19 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr5_+_157158205 0.18 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr7_-_97881429 0.17 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr6_-_112115074 0.17 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr11_+_65405556 0.16 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr15_+_26360970 0.15 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr2_-_183387430 0.14 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr9_-_130635741 0.14 ENST00000223836.10
AK1
adenylate kinase 1
chrX_+_120181457 0.13 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr11_-_26743546 0.13 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr12_+_58166370 0.12 ENST00000300209.8
METTL21B
methyltransferase like 21B
chr2_+_223162866 0.11 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr2_-_32490859 0.11 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr8_-_23315190 0.10 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr5_-_171433579 0.10 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr8_-_135522425 0.09 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr2_-_32490801 0.09 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr9_+_2158443 0.09 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_157670528 0.09 ENST00000368186.5
ENST00000496769.1
FCRL3
Fc receptor-like 3
chr9_+_2158485 0.09 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_60758814 0.09 ENST00000579432.1
ENST00000446119.2
MRC2
mannose receptor, C type 2
chr20_-_34117447 0.08 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173
chromosome 20 open reading frame 173
chr12_+_58166431 0.08 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr9_+_12775011 0.08 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr4_+_114214125 0.08 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chrX_-_13835147 0.08 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr1_+_100810575 0.08 ENST00000542213.1
CDC14A
cell division cycle 14A
chr5_-_171433819 0.08 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr3_+_62304648 0.08 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr10_+_133918175 0.08 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr20_-_30060816 0.08 ENST00000317676.2
DEFB124
defensin, beta 124
chr16_+_31119615 0.08 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
BCKDK
branched chain ketoacid dehydrogenase kinase
chr10_-_48416849 0.07 ENST00000249598.1
GDF2
growth differentiation factor 2
chr4_-_74088800 0.07 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr14_+_77292715 0.07 ENST00000393774.3
ENST00000555189.1
ENST00000450042.2
C14orf166B
chromosome 14 open reading frame 166B
chr2_-_183387283 0.07 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_+_97010424 0.07 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
FHL5
four and a half LIM domains 5
chr3_+_137717571 0.07 ENST00000343735.4
CLDN18
claudin 18
chr1_+_159272111 0.06 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr1_+_12524965 0.06 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr19_+_56368803 0.06 ENST00000587891.1
NLRP4
NLR family, pyrin domain containing 4
chr6_-_119031228 0.06 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr3_+_171758344 0.06 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chrX_-_13835461 0.05 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr4_+_25915896 0.05 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr2_+_186603355 0.05 ENST00000343098.5
FSIP2
fibrous sheath interacting protein 2
chr9_+_108424738 0.05 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr15_-_65503801 0.05 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr7_-_99573677 0.05 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr4_+_2814011 0.05 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr11_-_88796803 0.05 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr3_+_137728842 0.05 ENST00000183605.5
CLDN18
claudin 18
chr1_+_50569575 0.05 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr12_-_95397442 0.04 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chrX_+_107334895 0.04 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr5_-_114632307 0.04 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr15_+_63354769 0.04 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr12_+_50794730 0.04 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4
La ribonucleoprotein domain family, member 4
chr2_-_183387064 0.04 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_116502605 0.04 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_108994633 0.04 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_47489240 0.04 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr11_+_55650773 0.04 ENST00000449290.2
TRIM51
tripartite motif-containing 51
chr2_+_108994466 0.03 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr8_-_67976509 0.03 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chr20_+_57226841 0.03 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr4_+_2813946 0.03 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr21_-_36421401 0.03 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr14_-_69864993 0.02 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr14_-_51297197 0.02 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr11_+_120107344 0.02 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr10_+_51565108 0.02 ENST00000438493.1
ENST00000452682.1
NCOA4
nuclear receptor coactivator 4
chr19_+_57874835 0.02 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr8_+_67976593 0.02 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr3_-_131753830 0.02 ENST00000429747.1
CPNE4
copine IV
chr7_+_116502527 0.02 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr3_-_46069223 0.02 ENST00000309285.3
XCR1
chemokine (C motif) receptor 1
chr12_-_75723805 0.01 ENST00000409799.1
ENST00000409445.3
CAPS2
calcyphosine 2
chr10_+_18629628 0.01 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr15_+_54901540 0.01 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr10_+_51565188 0.01 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chrX_+_69509927 0.01 ENST00000374403.3
KIF4A
kinesin family member 4A
chr6_+_37400974 0.01 ENST00000455891.1
ENST00000373451.4
CMTR1
cap methyltransferase 1
chr1_-_99470558 0.01 ENST00000370188.3
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr2_+_181845843 0.00 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr5_+_156607829 0.00 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr7_+_107531580 0.00 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD
dihydrolipoamide dehydrogenase
chr1_-_44818599 0.00 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr4_-_113207048 0.00 ENST00000361717.3
TIFA
TRAF-interacting protein with forkhead-associated domain
chr10_-_69597810 0.00 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_-_205091115 0.00 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.3 2.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 0.8 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.5 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 2.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 1.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.0 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.8 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.5 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery