Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Name	miRBASE accession
hsa-miR-125a-5p Links miRBase	MIMAT0000443
hsa-miR-125b-5p Links miRBase	MIMAT0000423
hsa-miR-4319 Links miRBase	MIMAT0016870

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr20_+_58152524	1.80	ENST00000359926.3	PHACTR3	phosphatase and actin regulator 3
chr15_+_90744533	1.80	ENST00000411539.2	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr2_-_31360887	1.77	ENST00000420311.2 ENST00000356174.3 ENST00000324589.5	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr7_-_22233442	1.74	ENST00000401957.2	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_151483855	1.55	ENST00000427934.2 ENST00000271636.7	CGN	cingulin
chr10_+_82168240	1.51	ENST00000372187.5 ENST00000372185.1	FAM213A	family with sequence similarity 213, member A
chr19_-_49258606	1.46	ENST00000310160.3	FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr1_+_109792641	1.46	ENST00000271332.3	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2
chr13_-_86373536	1.40	ENST00000400286.2	SLITRK6	SLIT and NTRK-like family, member 6
chr12_+_83080659	1.38	ENST00000321196.3	TMTC2	transmembrane and tetratricopeptide repeat containing 2
chr1_+_160370344	1.37	ENST00000368061.2	VANGL2	VANGL planar cell polarity protein 2
chr2_+_18059906	1.35	ENST00000304101.4	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr12_+_56473628	1.31	ENST00000549282.1 ENST00000549061.1 ENST00000267101.3	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_26856236	1.26	ENST00000374168.2 ENST00000374166.4	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr10_+_82213904	1.22	ENST00000429989.3	TSPAN14	tetraspanin 14
chr6_+_1312675	1.19	ENST00000296839.2	FOXQ1	forkhead box Q1
chr6_+_138188551	1.18	ENST00000237289.4 ENST00000433680.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr12_-_54779511	1.16	ENST00000551109.1 ENST00000546970.1	ZNF385A	zinc finger protein 385A
chr17_+_38333263	1.14	ENST00000456989.2 ENST00000543876.1 ENST00000544503.1 ENST00000264644.6 ENST00000538884.1	RAPGEFL1	Rap guanine nucleotide exchange factor (GEF)-like 1
chr17_-_27507395	1.11	ENST00000354329.4 ENST00000527372.1	MYO18A	myosin XVIIIA
chr2_-_75788038	1.08	ENST00000393913.3 ENST00000410113.1	EVA1A	eva-1 homolog A (C. elegans)
chr11_-_46940074	1.07	ENST00000378623.1 ENST00000534404.1	LRP4	low density lipoprotein receptor-related protein 4
chr6_+_106546808	1.05	ENST00000369089.3	PRDM1	PR domain containing 1, with ZNF domain
chr8_-_66754172	1.05	ENST00000401827.3	PDE7A	phosphodiesterase 7A
chr2_+_75061108	1.04	ENST00000290573.2	HK2	hexokinase 2
chr11_+_58939965	1.01	ENST00000227451.3	DTX4	deltex homolog 4 (Drosophila)
chr15_-_59665062	1.01	ENST00000288235.4	MYO1E	myosin IE
chr15_+_74833518	0.96	ENST00000346246.5	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr3_+_186648274	0.95	ENST00000169298.3	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr5_-_175964366	0.95	ENST00000274811.4	RNF44	ring finger protein 44
chr15_-_44486632	0.94	ENST00000484674.1	FRMD5	FERM domain containing 5
chr10_+_95653687	0.93	ENST00000371408.3 ENST00000427197.1	SLC35G1	solute carrier family 35, member G1
chr17_+_55162453	0.93	ENST00000575322.1 ENST00000337714.3 ENST00000314126.3	AKAP1	A kinase (PRKA) anchor protein 1
chr11_-_118023490	0.90	ENST00000324727.4	SCN4B	sodium channel, voltage-gated, type IV, beta subunit
chr9_-_139137648	0.84	ENST00000358701.5	QSOX2	quiescin Q6 sulfhydryl oxidase 2
chr9_-_100935043	0.78	ENST00000343933.5	CORO2A	coronin, actin binding protein, 2A
chr18_-_43652211	0.74	ENST00000589328.1 ENST00000409746.5	PSTPIP2	proline-serine-threonine phosphatase interacting protein 2
chr1_+_33207381	0.74	ENST00000401073.2	KIAA1522	KIAA1522
chr4_-_80994210	0.74	ENST00000403729.2	ANTXR2	anthrax toxin receptor 2
chr9_+_116638562	0.71	ENST00000374126.5 ENST00000288466.7	ZNF618	zinc finger protein 618
chr7_-_139876812	0.71	ENST00000397560.2	JHDM1D	lysine (K)-specific demethylase 7A
chr11_-_64901978	0.69	ENST00000294256.8 ENST00000377190.3	SYVN1	synovial apoptosis inhibitor 1, synoviolin
chr3_-_52090461	0.69	ENST00000296483.6 ENST00000495880.1	DUSP7	dual specificity phosphatase 7
chr22_+_40390930	0.68	ENST00000333407.6	FAM83F	family with sequence similarity 83, member F
chr6_+_17281573	0.68	ENST00000379052.5	RBM24	RNA binding motif protein 24
chr2_-_9143786	0.67	ENST00000462696.1 ENST00000305997.3	MBOAT2	membrane bound O-acyltransferase domain containing 2
chr3_+_47021168	0.65	ENST00000450053.3 ENST00000292309.5 ENST00000383740.2	NBEAL2	neurobeachin-like 2
chr1_-_217262969	0.65	ENST00000361525.3	ESRRG	estrogen-related receptor gamma
chr10_-_73533255	0.64	ENST00000394957.3	C10orf54	chromosome 10 open reading frame 54
chr12_-_125348448	0.64	ENST00000339570.5	SCARB1	scavenger receptor class B, member 1
chr15_+_68871308	0.64	ENST00000261861.5	CORO2B	coronin, actin binding protein, 2B
chr1_-_43751230	0.62	ENST00000523677.1	C1orf210	chromosome 1 open reading frame 210
chr12_+_5019061	0.60	ENST00000382545.3	KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr6_-_40555176	0.58	ENST00000338305.6	LRFN2	leucine rich repeat and fibronectin type III domain containing 2
chr2_-_103353277	0.57	ENST00000258436.5	MFSD9	major facilitator superfamily domain containing 9
chr14_+_70078303	0.57	ENST00000342745.4	KIAA0247	KIAA0247
chr22_+_29279552	0.56	ENST00000544604.2	ZNRF3	zinc and ring finger 3
chr8_-_28243934	0.56	ENST00000521185.1 ENST00000520290.1 ENST00000344423.5	ZNF395	zinc finger protein 395
chr3_-_133748913	0.55	ENST00000310926.4	SLCO2A1	solute carrier organic anion transporter family, member 2A1
chr19_+_7968728	0.54	ENST00000397981.3 ENST00000545011.1 ENST00000397983.3 ENST00000397979.3	MAP2K7	mitogen-activated protein kinase kinase 7
chr10_-_118764862	0.54	ENST00000260777.10	KIAA1598	KIAA1598
chr12_+_11802753	0.53	ENST00000396373.4	ETV6	ets variant 6
chr1_-_200379180	0.53	ENST00000294740.3	ZNF281	zinc finger protein 281
chr13_+_41363581	0.52	ENST00000338625.4	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr17_+_53828381	0.52	ENST00000576183.1	PCTP	phosphatidylcholine transfer protein
chr7_-_98741642	0.51	ENST00000361368.2	SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr2_+_148602058	0.50	ENST00000241416.7 ENST00000535787.1 ENST00000404590.1	ACVR2A	activin A receptor, type IIA
chr17_-_57784755	0.49	ENST00000537860.1 ENST00000393038.2 ENST00000409433.2	PTRH2	peptidyl-tRNA hydrolase 2
chr3_+_126707437	0.49	ENST00000393409.2 ENST00000251772.4	PLXNA1	plexin A1
chr7_-_112430647	0.49	ENST00000312814.6	TMEM168	transmembrane protein 168
chr5_-_141257954	0.47	ENST00000456271.1 ENST00000394536.3 ENST00000503492.1 ENST00000287008.3	PCDH1	protocadherin 1
chr8_-_8751068	0.46	ENST00000276282.6	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr5_+_56111361	0.44	ENST00000399503.3	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr2_+_74881355	0.44	ENST00000357877.2	SEMA4F	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chrX_+_153639856	0.44	ENST00000426834.1 ENST00000369790.4 ENST00000454722.1 ENST00000350743.4 ENST00000299328.5 ENST00000351413.4	TAZ	tafazzin
chr3_+_5229356	0.43	ENST00000256497.4	EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr19_-_11450249	0.43	ENST00000222120.3	RAB3D	RAB3D, member RAS oncogene family
chr6_+_18387570	0.42	ENST00000259939.3	RNF144B	ring finger protein 144B
chr1_-_109940550	0.42	ENST00000256637.6	SORT1	sortilin 1
chr6_+_7107999	0.41	ENST00000491191.1 ENST00000379938.2 ENST00000471433.1	RREB1	ras responsive element binding protein 1
chrX_+_24483338	0.41	ENST00000379162.4 ENST00000441463.2	PDK3	pyruvate dehydrogenase kinase, isozyme 3
chr10_-_14590644	0.40	ENST00000378470.1	FAM107B	family with sequence similarity 107, member B
chr4_-_100575781	0.39	ENST00000511828.1	RP11-766F14.2	Protein LOC285556
chr3_+_58223228	0.39	ENST00000478253.1 ENST00000295962.4	ABHD6	abhydrolase domain containing 6
chr2_-_201828356	0.39	ENST00000234296.2	ORC2	origin recognition complex, subunit 2
chr1_-_111682662	0.39	ENST00000286692.4	DRAM2	DNA-damage regulated autophagy modulator 2
chr19_+_7660716	0.38	ENST00000160298.4 ENST00000446248.2	CAMSAP3	calmodulin regulated spectrin-associated protein family, member 3
chr12_+_45609893	0.37	ENST00000320560.8	ANO6	anoctamin 6
chr14_+_71374122	0.36	ENST00000304743.2 ENST00000238570.5	PCNX	pecanex homolog (Drosophila)
chr12_+_13197218	0.36	ENST00000197268.8	KIAA1467	KIAA1467
chr19_-_1863567	0.35	ENST00000250916.4	KLF16	Kruppel-like factor 16
chr16_-_23521710	0.35	ENST00000562117.1 ENST00000567468.1 ENST00000562944.1 ENST00000309859.4	GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr15_-_34659349	0.35	ENST00000314891.6	LPCAT4	lysophosphatidylcholine acyltransferase 4
chr1_+_203274639	0.34	ENST00000290551.4	BTG2	BTG family, member 2
chr3_-_183735731	0.34	ENST00000334444.6	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_-_2050852	0.34	ENST00000541165.1 ENST00000591601.1	MKNK2	MAP kinase interacting serine/threonine kinase 2
chr7_+_90032667	0.34	ENST00000496677.1 ENST00000287916.4 ENST00000535571.1 ENST00000394604.1 ENST00000394605.2	CLDN12	claudin 12
chr14_-_100070363	0.32	ENST00000380243.4	CCDC85C	coiled-coil domain containing 85C
chr10_-_71906342	0.32	ENST00000287078.6 ENST00000335494.5	TYSND1	trypsin domain containing 1
chr4_+_47487285	0.32	ENST00000273859.3 ENST00000504445.1	ATP10D	ATPase, class V, type 10D
chr16_+_68298405	0.32	ENST00000219343.6 ENST00000566834.1 ENST00000566454.1	SLC7A6	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr8_+_37887772	0.32	ENST00000338825.4	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1
chr15_-_79383102	0.32	ENST00000558480.2 ENST00000419573.3	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr4_-_111119804	0.31	ENST00000394607.3 ENST00000302274.3	ELOVL6	ELOVL fatty acid elongase 6
chr8_-_141645645	0.31	ENST00000519980.1 ENST00000220592.5	AGO2	argonaute RISC catalytic component 2
chr5_-_159739532	0.31	ENST00000520748.1 ENST00000393977.3 ENST00000257536.7	CCNJL	cyclin J-like
chr3_+_140770183	0.31	ENST00000310546.2	SPSB4	splA/ryanodine receptor domain and SOCS box containing 4
chr20_-_31071239	0.31	ENST00000359676.5	C20orf112	chromosome 20 open reading frame 112
chr12_-_57030115	0.30	ENST00000379441.3 ENST00000179765.5 ENST00000551812.1	BAZ2A	bromodomain adjacent to zinc finger domain, 2A
chr13_-_30169807	0.30	ENST00000380752.5	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_-_33547975	0.30	ENST00000442998.2 ENST00000360661.5	BAK1	BCL2-antagonist/killer 1
chr20_-_52790512	0.30	ENST00000216862.3	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1
chr18_-_19284724	0.30	ENST00000580981.1 ENST00000289119.2	ABHD3	abhydrolase domain containing 3
chr3_+_15468862	0.30	ENST00000396842.2	EAF1	ELL associated factor 1
chr14_+_23775971	0.29	ENST00000250405.5	BCL2L2	BCL2-like 2
chr8_-_144699628	0.29	ENST00000529048.1 ENST00000529064.1	TSTA3	tissue specific transplantation antigen P35B
chr3_-_53381539	0.29	ENST00000606822.1 ENST00000294241.6 ENST00000607628.1	DCP1A	decapping mRNA 1A
chr8_-_145550571	0.29	ENST00000332324.4	DGAT1	diacylglycerol O-acyltransferase 1
chr1_+_165796753	0.28	ENST00000367879.4	UCK2	uridine-cytidine kinase 2
chr5_+_57878859	0.28	ENST00000282878.4	RAB3C	RAB3C, member RAS oncogene family
chr15_-_23086394	0.28	ENST00000337435.4	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr18_-_29264669	0.28	ENST00000306851.5	B4GALT6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr2_+_191045562	0.28	ENST00000340623.4	C2orf88	chromosome 2 open reading frame 88
chr10_+_120967072	0.28	ENST00000392870.2	GRK5	G protein-coupled receptor kinase 5
chr11_+_45825896	0.28	ENST00000314134.3	SLC35C1	solute carrier family 35 (GDP-fucose transporter), member C1
chr6_-_16761678	0.27	ENST00000244769.4 ENST00000436367.1	ATXN1	ataxin 1
chr16_-_85045131	0.27	ENST00000313732.4	ZDHHC7	zinc finger, DHHC-type containing 7
chr6_+_138483058	0.27	ENST00000251691.4	KIAA1244	KIAA1244
chr17_-_40761375	0.26	ENST00000543197.1 ENST00000309428.5	FAM134C	family with sequence similarity 134, member C
chr12_+_50451331	0.26	ENST00000228468.4	ASIC1	acid-sensing (proton-gated) ion channel 1
chr1_-_6321035	0.26	ENST00000377893.2	GPR153	G protein-coupled receptor 153
chr9_+_77112244	0.26	ENST00000376896.3	RORB	RAR-related orphan receptor B
chr3_-_57678772	0.26	ENST00000311128.5	DENND6A	DENN/MADD domain containing 6A
chr15_-_72410109	0.26	ENST00000564571.1	MYO9A	myosin IXA
chr22_+_21771656	0.26	ENST00000407464.2	HIC2	hypermethylated in cancer 2
chr10_+_123748702	0.25	ENST00000369005.1 ENST00000513429.1 ENST00000515273.1 ENST00000515603.1	TACC2	transforming, acidic coiled-coil containing protein 2
chr9_-_19786926	0.25	ENST00000341998.2 ENST00000286344.3	SLC24A2	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr11_+_65554493	0.25	ENST00000335987.3	OVOL1	ovo-like zinc finger 1
chr10_-_15762124	0.24	ENST00000378076.3	ITGA8	integrin, alpha 8
chr12_-_57472522	0.24	ENST00000379391.3 ENST00000300128.4	TMEM194A	transmembrane protein 194A
chr20_+_62795827	0.24	ENST00000328439.1 ENST00000536311.1	MYT1	myelin transcription factor 1
chr3_+_127391769	0.24	ENST00000393363.3 ENST00000232744.8 ENST00000453791.2	ABTB1	ankyrin repeat and BTB (POZ) domain containing 1
chr1_+_26737253	0.24	ENST00000326279.6	LIN28A	lin-28 homolog A (C. elegans)
chr20_+_2673383	0.23	ENST00000380648.4 ENST00000342725.5	EBF4	early B-cell factor 4
chr17_+_73512594	0.23	ENST00000333213.6	TSEN54	TSEN54 tRNA splicing endonuclease subunit
chr8_+_22857048	0.23	ENST00000251822.6	RHOBTB2	Rho-related BTB domain containing 2
chr19_-_4066890	0.23	ENST00000322357.4	ZBTB7A	zinc finger and BTB domain containing 7A
chr19_+_45394477	0.23	ENST00000252487.5 ENST00000405636.2 ENST00000592434.1 ENST00000426677.2 ENST00000589649.1	TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_+_42846443	0.23	ENST00000410070.2 ENST00000431473.3	RIMKLA	ribosomal modification protein rimK-like family member A
chr6_-_80657292	0.22	ENST00000369816.4	ELOVL4	ELOVL fatty acid elongase 4
chr19_-_14629224	0.22	ENST00000254322.2	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chrX_+_48554986	0.22	ENST00000376687.3 ENST00000453214.2	SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr11_+_76494253	0.22	ENST00000333090.4	TSKU	tsukushi, small leucine rich proteoglycan
chr2_+_159313452	0.22	ENST00000389757.3 ENST00000389759.3	PKP4	plakophilin 4
chr16_+_1662326	0.22	ENST00000397412.3	CRAMP1L	Crm, cramped-like (Drosophila)
chr9_-_127533519	0.22	ENST00000487099.2 ENST00000344523.4 ENST00000373584.3	NR6A1	nuclear receptor subfamily 6, group A, member 1
chr2_+_124782857	0.21	ENST00000431078.1	CNTNAP5	contactin associated protein-like 5
chr4_+_111397216	0.21	ENST00000265162.5	ENPEP	glutamyl aminopeptidase (aminopeptidase A)
chr17_+_61086917	0.21	ENST00000424789.2 ENST00000389520.4	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr3_+_179065474	0.21	ENST00000471841.1 ENST00000280653.7	MFN1	mitofusin 1
chr10_+_72575643	0.21	ENST00000373202.3	SGPL1	sphingosine-1-phosphate lyase 1
chr14_-_75179774	0.21	ENST00000555249.1 ENST00000556202.1 ENST00000356357.4 ENST00000338772.5	AREL1 AC007956.1	apoptosis resistant E3 ubiquitin protein ligase 1 Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr19_-_2721412	0.21	ENST00000323469.4	DIRAS1	DIRAS family, GTP-binding RAS-like 1
chr11_-_102323489	0.21	ENST00000361236.3	TMEM123	transmembrane protein 123
chr6_+_125283566	0.21	ENST00000521654.2	RNF217	ring finger protein 217
chr19_+_40697514	0.20	ENST00000253055.3	MAP3K10	mitogen-activated protein kinase kinase kinase 10
chr22_+_41777927	0.20	ENST00000266304.4	TEF	thyrotrophic embryonic factor
chr11_-_119252359	0.20	ENST00000455332.2	USP2	ubiquitin specific peptidase 2
chr13_-_25746416	0.20	ENST00000515384.1 ENST00000357816.2	AMER2	APC membrane recruitment protein 2
chr19_+_11485333	0.20	ENST00000312423.2	SWSAP1	SWIM-type zinc finger 7 associated protein 1
chr1_-_157108130	0.19	ENST00000368192.4	ETV3	ets variant 3
chr17_-_12921270	0.19	ENST00000578071.1 ENST00000426905.3 ENST00000395962.2 ENST00000583371.1 ENST00000338034.4	ELAC2	elaC ribonuclease Z 2
chr2_+_241375069	0.19	ENST00000264039.2	GPC1	glypican 1
chr9_+_131102925	0.19	ENST00000372870.1 ENST00000300456.4	SLC27A4	solute carrier family 27 (fatty acid transporter), member 4
chr16_-_19729502	0.19	ENST00000219837.7	KNOP1	lysine-rich nucleolar protein 1
chr17_-_5372271	0.19	ENST00000225296.3	DHX33	DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr15_+_73344791	0.19	ENST00000261908.6	NEO1	neogenin 1
chr8_-_57906362	0.19	ENST00000262644.4	IMPAD1	inositol monophosphatase domain containing 1
chr3_+_32859510	0.19	ENST00000383763.5	TRIM71	tripartite motif containing 71, E3 ubiquitin protein ligase
chrX_+_64708615	0.19	ENST00000338957.4 ENST00000423889.3	ZC3H12B	zinc finger CCCH-type containing 12B
chr8_-_143484483	0.19	ENST00000519651.1 ENST00000307180.3 ENST00000518720.1 ENST00000524325.1	TSNARE1	t-SNARE domain containing 1
chr8_-_81787006	0.19	ENST00000327835.3	ZNF704	zinc finger protein 704
chr4_+_7194247	0.19	ENST00000507866.2	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr11_+_63606373	0.19	ENST00000402010.2 ENST00000315032.8 ENST00000377809.4 ENST00000413835.2 ENST00000377810.3	MARK2	MAP/microtubule affinity-regulating kinase 2
chr5_+_74632993	0.18	ENST00000287936.4	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr12_+_49932886	0.18	ENST00000257981.6	KCNH3	potassium voltage-gated channel, subfamily H (eag-related), member 3
chr17_+_27920486	0.18	ENST00000394859.3	ANKRD13B	ankyrin repeat domain 13B
chr17_+_80477571	0.18	ENST00000335255.5	FOXK2	forkhead box K2
chr9_+_101867359	0.18	ENST00000374994.4	TGFBR1	transforming growth factor, beta receptor 1
chr11_+_94277017	0.18	ENST00000358752.2	FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr11_-_65381643	0.17	ENST00000309100.3 ENST00000529839.1 ENST00000526293.1	MAP3K11	mitogen-activated protein kinase kinase kinase 11
chr15_-_73661605	0.17	ENST00000261917.3	HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr8_-_145559943	0.17	ENST00000332135.4	SCRT1	scratch family zinc finger 1
chr1_+_178694300	0.17	ENST00000367635.3	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2
chr2_+_220408724	0.17	ENST00000421791.1 ENST00000373883.3 ENST00000451952.1	TMEM198	transmembrane protein 198
chr11_+_114270752	0.17	ENST00000540163.1	RBM7	RNA binding motif protein 7
chr2_+_112812778	0.16	ENST00000283206.4	TMEM87B	transmembrane protein 87B
chrX_+_146993449	0.16	ENST00000218200.8 ENST00000370471.3 ENST00000370477.1	FMR1	fragile X mental retardation 1
chr1_+_155247207	0.16	ENST00000368358.3	HCN3	hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr6_+_116421976	0.16	ENST00000319550.4 ENST00000419791.1	NT5DC1	5'-nucleotidase domain containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.4	1.2	GO:0071947	B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.4	1.1	GO:1903028	positive regulation of opsonization(GO:1903028)
0.4	1.1	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2	1.4	GO:0060005	vestibular reflex(GO:0060005)
0.2	1.2	GO:1902162	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2	0.6	GO:0015920	lipopolysaccharide transport(GO:0015920)
0.2	1.1	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.2	1.3	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.5	GO:1902534	single-organism membrane invagination(GO:1902534)
0.2	0.3	GO:0048597	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1	0.6	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1	1.0	GO:1904925	negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1	1.5	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.1	1.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	1.6	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	0.9	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.1	GO:1901166	neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1	0.8	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.1	0.6	GO:2000051	Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1	0.4	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.3	GO:1903826	arginine transmembrane transport(GO:1903826)
0.1	0.3	GO:0042369	vitamin D catabolic process(GO:0042369)
0.1	0.3	GO:0042351	'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1	0.4	GO:0097045	phosphatidylserine exposure on blood platelet(GO:0097045)
0.1	0.5	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.2	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.1	0.5	GO:1903352	L-ornithine transmembrane transport(GO:1903352)
0.1	0.4	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.3	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1	0.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.3	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.3	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1	0.4	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1	1.0	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.5	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	0.6	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:1990180	mitochondrial tRNA 3'-end processing(GO:1990180)
0.1	0.3	GO:1990928	response to amino acid starvation(GO:1990928)
0.1	0.4	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.2	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	0.2	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.4	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.1	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1	0.2	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.1	2.3	GO:0050919	negative chemotaxis(GO:0050919)
0.1	1.3	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.3	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.0	0.1	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.3	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.0	0.9	GO:0086027	AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0	0.3	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.2	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	0.0	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	0.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.2	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0	0.4	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.5	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.3	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	0.1	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0	0.4	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.4	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.2	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.6	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	1.0	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.3	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0	0.2	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.2	GO:0044254	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0	0.4	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.3	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.8	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.5	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0051582	glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0	0.1	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.0	1.0	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.0	0.9	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.0	0.2	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.3	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.5	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	0.3	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.6	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0090212	vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0	0.5	GO:0030220	platelet formation(GO:0030220)
0.0	0.9	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.2	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.3	GO:0019882	antigen processing and presentation(GO:0019882)
0.0	0.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.2	GO:0001553	luteinization(GO:0001553)
0.0	0.0	GO:1904562	phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.8	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.8	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.2	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.1	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.7	GO:1901998	toxin transport(GO:1901998)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.3	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.0	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.4	GO:0060187	cell pole(GO:0060187)
0.2	0.7	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	0.4	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.1	0.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	1.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.5	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.2	GO:0098855	HCN channel complex(GO:0098855)
0.1	0.9	GO:0016600	flotillin complex(GO:0016600)
0.1	0.2	GO:0019034	viral replication complex(GO:0019034)
0.1	0.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.2	GO:0016938	kinesin I complex(GO:0016938)
0.0	0.2	GO:0097196	Shu complex(GO:0097196)
0.0	0.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.2	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.0	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.5	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.4	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	3.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.6	GO:0033270	paranode region of axon(GO:0033270)
0.0	3.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.4	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031905	early endosome lumen(GO:0031905)
0.0	0.2	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.4	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.3	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.1	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2	0.6	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.2	0.8	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2	0.9	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2	0.8	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	1.0	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	1.5	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.3	GO:0098808	mRNA cap binding(GO:0098808)
0.1	0.4	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	1.3	GO:0038132	neuregulin binding(GO:0038132)
0.1	2.2	GO:0038191	neuropilin binding(GO:0038191)
0.1	1.6	GO:0008417	fucosyltransferase activity(GO:0008417)
0.1	0.3	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.1	0.7	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.4	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.4	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	0.5	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	1.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.1	0.7	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1	0.5	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.4	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.5	GO:0098821	BMP receptor activity(GO:0098821)
0.1	0.3	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1	0.6	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	1.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.2	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.3	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.3	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	0.5	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	1.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	0.3	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.0	1.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	1.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.3	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	0.7	GO:0048185	activin binding(GO:0048185)
0.0	0.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	1.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.7	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.7	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.7	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.2	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.2	GO:0052833	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0	0.4	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.6	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	1.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.0	1.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0004849	uridine kinase activity(GO:0004849)
0.0	1.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.7	GO:0031489	myosin V binding(GO:0031489)
0.0	0.4	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	1.0	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.1	GO:0052656	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0	1.1	GO:0043531	ADP binding(GO:0043531)
0.0	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0002151	G-quadruplex RNA binding(GO:0002151) sequence-specific mRNA binding(GO:1990825)
0.0	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0008431	vitamin E binding(GO:0008431)
0.0	1.0	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.2	GO:0000182	rDNA binding(GO:0000182)
0.0	0.2	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.3	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.0	GO:0050405	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	2.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	1.3	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	1.8	GO:0003774	motor activity(GO:0003774)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.7	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.6	PID BMP PATHWAY	BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.0	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	1.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	1.3	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.5	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	1.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants