Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
CEBPA Links Ensembl NCBI GeneCards UniProt	ENSG00000245848.2	CEBPA

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPA	hg19_v2_chr19_-_33793430_33793470	0.54	1.7e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr20_-_43883197	5.63	ENST00000338380.2	SLPI	secretory leukocyte peptidase inhibitor
chr11_-_102668879	5.27	ENST00000315274.6	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr20_+_58630972	4.37	ENST00000313426.1	C20orf197	chromosome 20 open reading frame 197
chr18_+_61554932	3.55	ENST00000299502.4 ENST00000457692.1 ENST00000413956.1	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr19_-_35992780	3.14	ENST00000593342.1 ENST00000601650.1 ENST00000408915.2	DMKN	dermokine
chr19_-_36004543	2.92	ENST00000339686.3 ENST00000447113.2 ENST00000440396.1	DMKN	dermokine
chr11_-_18270182	2.87	ENST00000528349.1 ENST00000526900.1 ENST00000529528.1 ENST00000414546.2 ENST00000256733.4	SAA2	serum amyloid A2
chr10_+_118187379	2.76	ENST00000369230.3	PNLIPRP3	pancreatic lipase-related protein 3
chr11_+_18287721	2.74	ENST00000356524.4	SAA1	serum amyloid A1
chr2_-_113594279	2.74	ENST00000416750.1 ENST00000418817.1 ENST00000263341.2	IL1B	interleukin 1, beta
chr11_+_18287801	2.73	ENST00000532858.1 ENST00000405158.2	SAA1	serum amyloid A1
chr1_+_152486950	2.62	ENST00000368790.3	CRCT1	cysteine-rich C-terminal 1
chr19_-_6720686	2.62	ENST00000245907.6	C3	complement component 3
chr12_-_123201337	2.54	ENST00000528880.2	HCAR3	hydroxycarboxylic acid receptor 3
chr5_+_36608422	2.47	ENST00000381918.3	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_-_28622774	2.43	ENST00000434452.1	DSC3	desmocollin 3
chr18_-_28622699	2.41	ENST00000360428.4	DSC3	desmocollin 3
chr12_-_123187890	2.32	ENST00000328880.5	HCAR2	hydroxycarboxylic acid receptor 2
chr4_-_10023095	2.22	ENST00000264784.3	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr13_-_20805109	2.17	ENST00000241124.6	GJB6	gap junction protein, beta 6, 30kDa
chr12_-_95510743	2.14	ENST00000551521.1	FGD6	FYVE, RhoGEF and PH domain containing 6
chr12_+_29376592	2.12	ENST00000182377.4	FAR2	fatty acyl CoA reductase 2
chr9_+_130911770	1.99	ENST00000372998.1	LCN2	lipocalin 2
chr2_+_223289208	1.92	ENST00000321276.7	SGPP2	sphingosine-1-phosphate phosphatase 2
chr10_-_116444371	1.85	ENST00000533213.2 ENST00000369252.4	ABLIM1	actin binding LIM protein 1
chr6_-_41130841	1.80	ENST00000373122.4	TREM2	triggering receptor expressed on myeloid cells 2
chr12_+_29376673	1.77	ENST00000547116.1	FAR2	fatty acyl CoA reductase 2
chr9_+_130911723	1.72	ENST00000277480.2 ENST00000373013.2 ENST00000540948.1	LCN2	lipocalin 2
chr6_-_41130914	1.62	ENST00000373113.3 ENST00000338469.3	TREM2	triggering receptor expressed on myeloid cells 2
chr14_+_96722539	1.59	ENST00000553356.1	BDKRB1	bradykinin receptor B1
chr1_-_186649543	1.51	ENST00000367468.5	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr5_+_140227048	1.45	ENST00000532602.1	PCDHA9	protocadherin alpha 9
chr7_+_26191809	1.34	ENST00000056233.3	NFE2L3	nuclear factor, erythroid 2-like 3
chr10_-_45474237	1.32	ENST00000448778.1 ENST00000298295.3	C10orf10	chromosome 10 open reading frame 10
chr2_-_31637560	1.24	ENST00000379416.3	XDH	xanthine dehydrogenase
chr6_+_30848557	1.23	ENST00000460944.2 ENST00000324771.8	DDR1	discoidin domain receptor tyrosine kinase 1
chr18_-_61329118	1.23	ENST00000332821.8 ENST00000283752.5	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr17_-_76124711	1.17	ENST00000306591.7 ENST00000590602.1	TMC6	transmembrane channel-like 6
chr19_-_54676846	1.17	ENST00000301187.4	TMC4	transmembrane channel-like 4
chr1_+_82266053	1.15	ENST00000370715.1 ENST00000370713.1 ENST00000319517.6 ENST00000370717.2 ENST00000394879.1 ENST00000271029.4 ENST00000335786.5	LPHN2	latrophilin 2
chr2_+_102608306	1.14	ENST00000332549.3	IL1R2	interleukin 1 receptor, type II
chr6_+_106534192	1.08	ENST00000369091.2 ENST00000369096.4	PRDM1	PR domain containing 1, with ZNF domain
chr7_+_18535786	1.08	ENST00000406072.1	HDAC9	histone deacetylase 9
chr8_+_18248786	1.07	ENST00000520116.1	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr12_-_86230315	1.05	ENST00000361228.3	RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr6_-_11779014	1.04	ENST00000229583.5	ADTRP	androgen-dependent TFPI-regulating protein
chr19_-_54676884	1.03	ENST00000376591.4	TMC4	transmembrane channel-like 4
chr8_+_18248755	0.99	ENST00000286479.3	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr21_+_43619796	0.99	ENST00000398457.2	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr17_-_76124812	0.98	ENST00000592063.1 ENST00000589271.1 ENST00000322933.4 ENST00000589553.1	TMC6	transmembrane channel-like 6
chr13_+_78109884	0.98	ENST00000377246.3 ENST00000349847.3	SCEL	sciellin
chr13_+_78109804	0.97	ENST00000535157.1	SCEL	sciellin
chr12_+_21207503	0.94	ENST00000545916.1	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_+_62439037	0.93	ENST00000545929.1	INADL	InaD-like (Drosophila)
chr1_-_153029980	0.93	ENST00000392653.2	SPRR2A	small proline-rich protein 2A
chr12_+_101188547	0.90	ENST00000546991.1 ENST00000392979.3	ANO4	anoctamin 4
chr1_+_111770278	0.90	ENST00000369748.4	CHI3L2	chitinase 3-like 2
chr1_+_111770232	0.90	ENST00000369744.2	CHI3L2	chitinase 3-like 2
chr9_-_140196703	0.89	ENST00000356628.2	NRARP	NOTCH-regulated ankyrin repeat protein
chr12_+_101188718	0.88	ENST00000299222.9 ENST00000392977.3	ANO4	anoctamin 4
chr4_-_139163491	0.86	ENST00000280612.5	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr19_+_50084561	0.83	ENST00000246794.5	PRRG2	proline rich Gla (G-carboxyglutamic acid) 2
chr2_-_101925055	0.83	ENST00000295317.3	RNF149	ring finger protein 149
chr11_+_117947782	0.82	ENST00000522307.1 ENST00000523251.1 ENST00000437212.3 ENST00000522824.1 ENST00000522151.1	TMPRSS4	transmembrane protease, serine 4
chr1_-_114429997	0.82	ENST00000471267.1 ENST00000393320.3	BCL2L15	BCL2-like 15
chr12_+_19358228	0.80	ENST00000424268.1 ENST00000543806.1	PLEKHA5	pleckstrin homology domain containing, family A member 5
chr1_+_196743912	0.80	ENST00000367425.4	CFHR3	complement factor H-related 3
chr16_+_82090028	0.79	ENST00000568090.1	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr6_+_47666275	0.78	ENST00000327753.3 ENST00000283303.2	GPR115	G protein-coupled receptor 115
chr1_+_196743943	0.75	ENST00000471440.2 ENST00000391985.3	CFHR3	complement factor H-related 3
chr1_-_207095324	0.74	ENST00000530505.1 ENST00000367091.3 ENST00000442471.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr2_-_18770812	0.73	ENST00000359846.2 ENST00000304081.4 ENST00000600945.1 ENST00000532967.1 ENST00000444297.2	NT5C1B NT5C1B-RDH14	5'-nucleotidase, cytosolic IB NT5C1B-RDH14 readthrough
chr14_+_22782867	0.73	ENST00000390467.3	TRAV40	T cell receptor alpha variable 40
chr9_-_117568365	0.73	ENST00000374045.4	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15
chrX_+_105192423	0.72	ENST00000540278.1	NRK	Nik related kinase
chr7_-_32111009	0.72	ENST00000396184.3 ENST00000396189.2 ENST00000321453.7	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr8_+_118533049	0.72	ENST00000522839.1	MED30	mediator complex subunit 30
chr8_+_27348649	0.71	ENST00000521780.1 ENST00000380476.3 ENST00000518379.1 ENST00000521684.1	EPHX2	epoxide hydrolase 2, cytoplasmic
chr2_+_163200598	0.70	ENST00000437150.2 ENST00000453113.2	GCA	grancalcin, EF-hand calcium binding protein
chr14_+_96722152	0.70	ENST00000216629.6	BDKRB1	bradykinin receptor B1
chr12_+_41831485	0.70	ENST00000539469.2 ENST00000298919.7	PDZRN4	PDZ domain containing ring finger 4
chr21_-_46348626	0.70	ENST00000517563.1	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr18_-_61311485	0.69	ENST00000436264.1 ENST00000356424.6 ENST00000341074.5	SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr6_+_150920999	0.62	ENST00000367328.1 ENST00000367326.1	PLEKHG1	pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr8_+_118532937	0.62	ENST00000297347.3	MED30	mediator complex subunit 30
chr1_+_152658599	0.60	ENST00000368780.3	LCE2B	late cornified envelope 2B
chr11_+_7597639	0.60	ENST00000533792.1	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_-_53409890	0.60	ENST00000229416.6	GCLC	glutamate-cysteine ligase, catalytic subunit
chr18_-_52989525	0.58	ENST00000457482.3	TCF4	transcription factor 4
chr1_+_196857144	0.58	ENST00000367416.2 ENST00000251424.4 ENST00000367418.2	CFHR4	complement factor H-related 4
chr1_+_107682629	0.57	ENST00000370074.4 ENST00000370073.2 ENST00000370071.2 ENST00000542803.1 ENST00000370061.3 ENST00000370072.3 ENST00000370070.2	NTNG1	netrin G1
chr12_+_21168630	0.57	ENST00000421593.2	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr14_-_81893734	0.57	ENST00000555447.1	STON2	stonin 2
chr11_-_104972158	0.56	ENST00000598974.1 ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1	CASP1 CARD16 CARD17	caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17
chr18_-_53070913	0.53	ENST00000568186.1 ENST00000564228.1	TCF4	transcription factor 4
chr4_-_90756769	0.52	ENST00000345009.4 ENST00000505199.1 ENST00000502987.1	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr2_+_220306745	0.52	ENST00000431523.1 ENST00000396698.1 ENST00000396695.2	SPEG	SPEG complex locus
chr10_-_75676400	0.52	ENST00000412307.2	C10orf55	chromosome 10 open reading frame 55
chr4_-_153274078	0.52	ENST00000263981.5	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chrY_-_20935572	0.51	ENST00000382852.1 ENST00000344884.4 ENST00000304790.3	HSFY2	heat shock transcription factor, Y linked 2
chr3_-_123339343	0.51	ENST00000578202.1	MYLK	myosin light chain kinase
chr12_-_10007448	0.51	ENST00000538152.1	CLEC2B	C-type lectin domain family 2, member B
chr11_-_104905840	0.51	ENST00000526568.1 ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3	CASP1	caspase 1, apoptosis-related cysteine peptidase
chr14_-_106781017	0.50	ENST00000390612.2	IGHV4-28	immunoglobulin heavy variable 4-28
chr5_+_147258266	0.49	ENST00000296694.4	SCGB3A2	secretoglobin, family 3A, member 2
chr3_-_4793274	0.48	ENST00000414938.1	EGOT	eosinophil granule ontogeny transcript (non-protein coding)
chr17_+_56315787	0.48	ENST00000262290.4 ENST00000421678.2	LPO	lactoperoxidase
chrY_+_20708557	0.48	ENST00000307393.2 ENST00000309834.4 ENST00000382856.2	HSFY1	heat shock transcription factor, Y-linked 1
chr6_+_130339710	0.48	ENST00000526087.1 ENST00000533560.1 ENST00000361794.2	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr3_-_112693865	0.47	ENST00000471858.1 ENST00000295863.4 ENST00000308611.3	CD200R1	CD200 receptor 1
chr6_-_32557610	0.47	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr3_-_123339418	0.47	ENST00000583087.1	MYLK	myosin light chain kinase
chr7_+_123241908	0.47	ENST00000434204.1 ENST00000437535.1 ENST00000451215.1	ASB15	ankyrin repeat and SOCS box containing 15
chr3_-_112218205	0.47	ENST00000383680.4	BTLA	B and T lymphocyte associated
chr19_-_56249740	0.46	ENST00000590200.1 ENST00000332836.2	NLRP9	NLR family, pyrin domain containing 9
chr12_-_48963829	0.45	ENST00000301046.2 ENST00000549817.1	LALBA	lactalbumin, alpha-
chr7_-_121944491	0.45	ENST00000331178.4 ENST00000427185.2 ENST00000442488.2	FEZF1	FEZ family zinc finger 1
chr11_+_60050026	0.45	ENST00000395016.3	MS4A4A	membrane-spanning 4-domains, subfamily A, member 4A
chr6_-_30043539	0.44	ENST00000376751.3 ENST00000244360.6	RNF39	ring finger protein 39
chr12_+_20963647	0.43	ENST00000381545.3	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr12_-_46662772	0.43	ENST00000549049.1 ENST00000439706.1 ENST00000398637.5	SLC38A1	solute carrier family 38, member 1
chr11_-_101454658	0.43	ENST00000344327.3	TRPC6	transient receptor potential cation channel, subfamily C, member 6
chr8_-_72459885	0.43	ENST00000523987.1	RP11-1102P16.1	Uncharacterized protein
chr12_+_47473369	0.43	ENST00000546455.1	PCED1B	PC-esterase domain containing 1B
chr12_+_20963632	0.43	ENST00000540853.1 ENST00000261196.2	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr11_+_60048004	0.43	ENST00000532114.1	MS4A4A	membrane-spanning 4-domains, subfamily A, member 4A
chr2_+_196521458	0.42	ENST00000409086.3	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr1_-_114430169	0.42	ENST00000393316.3	BCL2L15	BCL2-like 15
chr2_+_65663812	0.42	ENST00000606978.1 ENST00000377977.3 ENST00000536804.1	AC074391.1	AC074391.1
chr1_-_153321301	0.42	ENST00000368739.3	PGLYRP4	peptidoglycan recognition protein 4
chr3_+_118905564	0.42	ENST00000460625.1	UPK1B	uroplakin 1B
chr16_-_2059797	0.41	ENST00000563630.1	ZNF598	zinc finger protein 598
chr5_+_140227357	0.41	ENST00000378122.3	PCDHA9	protocadherin alpha 9
chr3_-_143567262	0.40	ENST00000474151.1 ENST00000316549.6	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr10_-_61900762	0.40	ENST00000355288.2	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_39288092	0.39	ENST00000323947.7 ENST00000297668.6 ENST00000377656.2 ENST00000377659.1	CNTNAP3	contactin associated protein-like 3
chr7_+_107224364	0.39	ENST00000491150.1	BCAP29	B-cell receptor-associated protein 29
chr12_-_323689	0.39	ENST00000428720.1	SLC6A12	solute carrier family 6 (neurotransmitter transporter), member 12
chr4_-_87028478	0.39	ENST00000515400.1 ENST00000395157.3	MAPK10	mitogen-activated protein kinase 10
chr17_+_72426891	0.39	ENST00000392627.1	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr10_+_95517566	0.38	ENST00000542308.1	LGI1	leucine-rich, glioma inactivated 1
chr10_+_95517616	0.38	ENST00000371418.4	LGI1	leucine-rich, glioma inactivated 1
chr3_+_10857885	0.38	ENST00000254488.2 ENST00000454147.1	SLC6A11	solute carrier family 6 (neurotransmitter transporter), member 11
chr12_+_12966250	0.38	ENST00000352940.4 ENST00000358007.3 ENST00000544400.1	DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr1_-_54304212	0.38	ENST00000540001.1	NDC1	NDC1 transmembrane nucleoporin
chr3_+_118892362	0.38	ENST00000497685.1 ENST00000264234.3	UPK1B	uroplakin 1B
chr2_-_46769694	0.38	ENST00000522587.1	ATP6V1E2	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr3_-_112693759	0.38	ENST00000440122.2 ENST00000490004.1	CD200R1	CD200 receptor 1
chr19_-_54876558	0.37	ENST00000391742.2 ENST00000434277.2	LAIR1	leukocyte-associated immunoglobulin-like receptor 1
chr3_+_48264816	0.37	ENST00000296435.2 ENST00000576243.1	CAMP	cathelicidin antimicrobial peptide
chr14_+_22739823	0.37	ENST00000390464.2	TRAV38-1	T cell receptor alpha variable 38-1
chr6_+_144185573	0.37	ENST00000237275.6 ENST00000539295.1	ZC2HC1B	zinc finger, C2HC-type containing 1B
chr12_+_20522179	0.36	ENST00000359062.3	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr1_-_52521831	0.36	ENST00000371626.4	TXNDC12	thioredoxin domain containing 12 (endoplasmic reticulum)
chr17_-_34270697	0.36	ENST00000585556.1	LYZL6	lysozyme-like 6
chr10_+_97515409	0.35	ENST00000371207.3 ENST00000543964.1	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr9_+_27524283	0.35	ENST00000276943.2	IFNK	interferon, kappa
chr17_+_57287228	0.35	ENST00000578922.1 ENST00000300917.5	SMG8	SMG8 nonsense mediated mRNA decay factor
chr6_+_26087646	0.35	ENST00000309234.6	HFE	hemochromatosis
chr11_-_58980342	0.35	ENST00000361050.3	MPEG1	macrophage expressed 1
chr14_-_23285011	0.35	ENST00000397532.3	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_+_59824127	0.35	ENST00000278865.3	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_+_56315936	0.34	ENST00000543544.1	LPO	lactoperoxidase
chr11_+_59824060	0.34	ENST00000395032.2 ENST00000358152.2	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr16_+_56899114	0.34	ENST00000566786.1 ENST00000438926.2 ENST00000563236.1 ENST00000262502.5	SLC12A3	solute carrier family 12 (sodium/chloride transporter), member 3
chr10_+_26727125	0.33	ENST00000376236.4	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_+_60048053	0.33	ENST00000337908.4	MS4A4A	membrane-spanning 4-domains, subfamily A, member 4A
chr14_+_24540046	0.33	ENST00000397016.2 ENST00000537691.1 ENST00000560356.1 ENST00000558450.1	CPNE6	copine VI (neuronal)
chrX_+_16141667	0.32	ENST00000380289.2	GRPR	gastrin-releasing peptide receptor
chr19_+_45394477	0.32	ENST00000252487.5 ENST00000405636.2 ENST00000592434.1 ENST00000426677.2 ENST00000589649.1	TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr13_+_96085847	0.32	ENST00000376873.3	CLDN10	claudin 10
chr3_-_197300194	0.32	ENST00000358186.2 ENST00000431056.1	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr5_+_161494521	0.32	ENST00000356592.3	GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr11_+_55594695	0.32	ENST00000378397.1	OR5L2	olfactory receptor, family 5, subfamily L, member 2
chr18_-_19283649	0.31	ENST00000584464.1 ENST00000578270.1	ABHD3	abhydrolase domain containing 3
chr19_-_36019123	0.31	ENST00000588674.1 ENST00000452271.2 ENST00000518157.1	SBSN	suprabasin
chr4_+_144434584	0.31	ENST00000283131.3	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr5_+_140430979	0.31	ENST00000306549.3	PCDHB1	protocadherin beta 1
chr11_-_128737163	0.31	ENST00000324003.3 ENST00000392665.2	KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1
chr5_-_145483932	0.31	ENST00000311450.4	PLAC8L1	PLAC8-like 1
chr14_-_64194745	0.31	ENST00000247225.6	SGPP1	sphingosine-1-phosphate phosphatase 1
chr16_-_2059748	0.31	ENST00000562103.1 ENST00000431526.1	ZNF598	zinc finger protein 598
chr17_+_4336955	0.31	ENST00000355530.2	SPNS3	spinster homolog 3 (Drosophila)
chr17_-_73840415	0.31	ENST00000592386.1 ENST00000412096.2 ENST00000586147.1	UNC13D	unc-13 homolog D (C. elegans)
chr19_+_6887571	0.31	ENST00000250572.8 ENST00000381407.5 ENST00000312053.4 ENST00000450315.3 ENST00000381404.4	EMR1	egf-like module containing, mucin-like, hormone receptor-like 1
chr11_-_110583451	0.30	ENST00000260283.4 ENST00000528829.1	ARHGAP20	Rho GTPase activating protein 20
chr21_-_46348694	0.30	ENST00000355153.4 ENST00000397850.2	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_67519782	0.30	ENST00000235345.5	SLC35D1	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chrX_-_138914394	0.30	ENST00000327569.3 ENST00000361648.2 ENST00000370543.1 ENST00000359686.2	ATP11C	ATPase, class VI, type 11C
chr11_+_63137251	0.30	ENST00000310969.4 ENST00000279178.3	SLC22A9	solute carrier family 22 (organic anion transporter), member 9
chr11_-_128737259	0.30	ENST00000440599.2 ENST00000392666.1 ENST00000324036.3	KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1
chr17_-_69198295	0.30	ENST00000569074.1	CASC17	cancer susceptibility candidate 17 (non-protein coding)
chr6_-_33037019	0.29	ENST00000437811.1	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1
chr1_-_154458520	0.29	ENST00000486773.1	SHE	Src homology 2 domain containing E
chr16_+_56969284	0.29	ENST00000568358.1	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr10_-_113943447	0.29	ENST00000369425.1 ENST00000348367.4 ENST00000423155.1	GPAM	glycerol-3-phosphate acyltransferase, mitochondrial
chr21_+_34775181	0.29	ENST00000290219.6	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr7_+_1126437	0.29	ENST00000413368.1 ENST00000397092.1	GPER1	G protein-coupled estrogen receptor 1
chr14_-_23285069	0.28	ENST00000554758.1 ENST00000397528.4	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_17862274	0.28	ENST00000596536.1 ENST00000593870.1 ENST00000598086.1 ENST00000598932.1 ENST00000595023.1 ENST00000594068.1 ENST00000596507.1 ENST00000595033.1 ENST00000597718.1	FCHO1	FCH domain only 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.4	GO:0032499	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
1.0	6.1	GO:1903575	cornified envelope assembly(GO:1903575)
0.9	2.7	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.9	2.6	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.7	3.7	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6	3.9	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5	1.5	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.4	2.3	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.3	2.4	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3	1.2	GO:0046110	xanthine metabolic process(GO:0046110)
0.3	1.2	GO:0035425	autocrine signaling(GO:0035425)
0.3	0.9	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3	1.1	GO:0050712	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3	1.1	GO:0050717	regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2	1.0	GO:0055099	detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.2	0.7	GO:0060722	spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2	1.8	GO:0061588	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2	1.1	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.2	0.6	GO:0097069	cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2	0.6	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2	0.7	GO:0072344	rescue of stalled ribosome(GO:0072344)
0.2	0.5	GO:0030264	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.2	0.7	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.2	5.8	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.2	0.5	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1	0.4	GO:0051714	positive regulation of cytolysis in other organism(GO:0051714)
0.1	2.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.1	1.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	5.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	0.4	GO:0070631	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1	2.1	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.3	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	1.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	5.3	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.6	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1	0.5	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1	0.5	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.3	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.4	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.9	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.4	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.1	0.2	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	0.3	GO:0060133	somatotropin secreting cell development(GO:0060133)
0.1	2.5	GO:0042730	fibrinolysis(GO:0042730)
0.1	0.4	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	0.5	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	0.2	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.2	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.2	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	3.4	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.1	0.3	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.4	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1	0.2	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	2.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	0.4	GO:0071321	cellular response to cGMP(GO:0071321)
0.1	0.2	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	0.2	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1	0.1	GO:0015827	tryptophan transport(GO:0015827)
0.1	2.3	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1	0.2	GO:0035281	pre-miRNA export from nucleus(GO:0035281)
0.1	0.8	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.1	0.4	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.2	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.1	0.7	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.2	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.2	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1	0.3	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	1.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.4	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0	0.2	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0	0.4	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.3	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.7	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.8	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.3	GO:0036343	psychomotor behavior(GO:0036343)
0.0	0.2	GO:1900920	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0	0.6	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	5.7	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.2	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0	0.3	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0	0.4	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.2	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0	0.5	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.3	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.3	GO:0008217	regulation of blood pressure(GO:0008217)
0.0	2.2	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.3	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.3	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.3	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0003218	cardiac left ventricle formation(GO:0003218)
0.0	0.3	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	2.7	GO:0050918	positive chemotaxis(GO:0050918)
0.0	0.7	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.4	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.4	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.4	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.4	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.5	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.3	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.8	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.6	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.1	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.3	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.2	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.1	GO:1904640	response to methionine(GO:1904640)
0.0	0.1	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.3	GO:0043320	natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0	0.2	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0	0.3	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.4	GO:0002323	natural killer cell activation involved in immune response(GO:0002323)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.0	0.1	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.4	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.3	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.1	GO:2000525	defense response to nematode(GO:0002215) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.1	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.0	0.2	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.1	GO:0035897	proteolysis in other organism(GO:0035897)
0.0	0.1	GO:0090579	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.2	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.1	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	1.0	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	1.3	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.6	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.2	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.2	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.4	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	0.1	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.8	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.8	GO:0006195	purine nucleotide catabolic process(GO:0006195)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0097179	protease inhibitor complex(GO:0097179)
0.2	5.8	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	0.6	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.1	1.0	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.1	4.8	GO:0030057	desmosome(GO:0030057)
0.1	0.8	GO:1990037	Lewy body core(GO:1990037)
0.1	0.4	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	3.9	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	0.6	GO:1990357	terminal web(GO:1990357)
0.1	2.2	GO:0005922	connexon complex(GO:0005922)
0.1	3.1	GO:0001533	cornified envelope(GO:0001533)
0.1	0.3	GO:0031213	RSF complex(GO:0031213)
0.1	0.5	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	1.0	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	0.2	GO:0031251	PAN complex(GO:0031251)
0.1	0.2	GO:0042565	RNA nuclear export complex(GO:0042565)
0.1	2.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.5	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.4	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.2	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	2.9	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0	0.7	GO:0042611	MHC protein complex(GO:0042611)
0.0	3.8	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.4	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	3.2	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	2.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	1.0	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.4	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.3	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.5	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.0	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.1	GO:0001674	female germ cell nucleus(GO:0001674)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.9	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.8	2.3	GO:0004947	bradykinin receptor activity(GO:0004947)
0.5	2.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.5	3.4	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.4	2.5	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.3	1.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3	1.0	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.3	1.2	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2	1.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2	1.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2	0.6	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.2	2.5	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2	0.5	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.2	8.3	GO:0042056	chemoattractant activity(GO:0042056)
0.2	0.9	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	1.2	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.8	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.4	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1	2.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.7	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.6	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.1	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.3	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	0.5	GO:0004461	lactose synthase activity(GO:0004461)
0.1	2.5	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	1.0	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.1	0.4	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.1	0.3	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.4	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1	0.5	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	0.2	GO:0019862	IgA binding(GO:0019862)
0.1	0.3	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.1	1.8	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	1.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	2.7	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.3	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.6	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	1.1	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.8	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.2	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.2	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1	0.2	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	0.3	GO:0004966	galanin receptor activity(GO:0004966)
0.1	0.4	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.5	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	1.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.3	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	1.2	GO:0050700	CARD domain binding(GO:0050700)
0.1	7.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.3	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.1	0.2	GO:0090631	pre-miRNA transporter activity(GO:0090631)
0.1	1.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.7	GO:0004568	chitinase activity(GO:0004568)
0.0	0.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.7	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.2	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.1	GO:0002134	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.4	GO:0015288	porin activity(GO:0015288)
0.0	0.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.0	4.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.4	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.4	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	1.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.3	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.5	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0	0.3	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.8	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.3	GO:0005549	odorant binding(GO:0005549)
0.0	3.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.0	0.0	GO:0017129	triglyceride binding(GO:0017129)
0.0	0.4	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.4	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.0	0.3	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	3.4	GO:0005506	iron ion binding(GO:0005506)
0.0	0.1	GO:0031783	corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0	0.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.0	1.6	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.3	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.4	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.8	GO:0004601	peroxidase activity(GO:0004601)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.0	0.8	GO:0043022	ribosome binding(GO:0043022)
0.0	0.3	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	4.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	5.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	1.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	2.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.4	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	1.0	PID MYC PATHWAY	C-MYC pathway
0.0	4.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.3	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	5.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	3.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	3.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	3.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	2.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	4.8	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	0.9	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	2.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	1.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.4	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	1.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.6	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	5.5	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.8	REACTOME AMYLOIDS	Genes involved in Amyloids