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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for DLX1_HOXA3_BARX2

Z-value: 0.33

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol Gene ID Gene Info
DLX1
ENSG00000144355.10 DLX1
HOXA3
ENSG00000105997.18 HOXA3
BARX2
ENSG00000043039.5 BARX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BARX2hg19_v2_chr11_+_129245796_1292458350.811.4e-02Click!
DLX1hg19_v2_chr2_+_172949468_1729495220.363.8e-01Click!

Activity profile of DLX1_HOXA3_BARX2 motif

Sorted Z-values of DLX1_HOXA3_BARX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_36001113 0.64 ENST00000434389.1
 DMKN
 dermokine
chr8_-_41166953 0.52 ENST00000220772.3
 SFRP1
 secreted frizzled-related protein 1
chr10_-_135379132 0.48 ENST00000343131.5
 SYCE1
 synaptonemal complex central element protein 1
chr10_+_6779326 0.47 ENST00000417112.1
 RP11-554I8.2
 RP11-554I8.2
chr1_+_160370344 0.44 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chr3_-_151034734 0.43 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr10_-_105845674 0.33 ENST00000353479.5
ENST00000369733.3
 COL17A1
 collagen, type XVII, alpha 1
chr4_-_74486217 0.31 ENST00000335049.5
ENST00000307439.5
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr18_+_34124507 0.31 ENST00000591635.1
 FHOD3
 formin homology 2 domain containing 3
chr2_+_228736335 0.29 ENST00000440997.1
ENST00000545118.1
 DAW1
 dynein assembly factor with WDR repeat domains 1
chr4_-_25865159 0.28 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
 SEL1L3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
chr13_+_32313658 0.27 ENST00000380314.1
ENST00000298386.2
 RXFP2
 relaxin/insulin-like family peptide receptor 2
chr5_+_66300446 0.26 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr17_-_2996290 0.26 ENST00000331459.1
 OR1D2
 olfactory receptor, family 1, subfamily D, member 2
chr14_+_61654271 0.25 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
 PRKCH
 protein kinase C, eta
chr3_+_111718036 0.24 ENST00000455401.2
 TAGLN3
 transgelin 3
chr1_-_242612779 0.24 ENST00000427495.1
 PLD5
 phospholipase D family, member 5
chr3_+_111717600 0.24 ENST00000273368.4
 TAGLN3
 transgelin 3
chr3_+_111718173 0.24 ENST00000494932.1
 TAGLN3
 transgelin 3
chr1_+_28261492 0.23 ENST00000373894.3
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr4_+_119810134 0.23 ENST00000434046.2
 SYNPO2
 synaptopodin 2
chr15_+_43886057 0.22 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
 CKMT1B
 creatine kinase, mitochondrial 1B
chr11_-_26593779 0.22 ENST00000529533.1
 MUC15
 mucin 15, cell surface associated
chr3_+_111717511 0.22 ENST00000478951.1
ENST00000393917.2
 TAGLN3
 transgelin 3
chr11_-_26593677 0.21 ENST00000527569.1
 MUC15
 mucin 15, cell surface associated
chr2_+_228736321 0.21 ENST00000309931.2
 DAW1
 dynein assembly factor with WDR repeat domains 1
chr15_+_43985725 0.21 ENST00000413453.2
 CKMT1A
 creatine kinase, mitochondrial 1A
chr9_-_5304432 0.21 ENST00000416837.1
ENST00000308420.3
 RLN2
 relaxin 2
chr1_+_81771806 0.21 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr16_-_28634874 0.20 ENST00000395609.1
ENST00000350842.4
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr13_-_86373536 0.20 ENST00000400286.2
 SLITRK6
 SLIT and NTRK-like family, member 6
chr12_-_95510743 0.20 ENST00000551521.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr5_+_55149150 0.18 ENST00000297015.3
 IL31RA
 interleukin 31 receptor A
chr4_-_87028478 0.18 ENST00000515400.1
ENST00000395157.3
 MAPK10
 mitogen-activated protein kinase 10
chr6_-_9933500 0.18 ENST00000492169.1
 OFCC1
 orofacial cleft 1 candidate 1
chr10_-_14590644 0.17 ENST00000378470.1
 FAM107B
 family with sequence similarity 107, member B
chr6_-_28411241 0.16 ENST00000289788.4
 ZSCAN23
 zinc finger and SCAN domain containing 23
chr1_+_62439037 0.16 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr11_-_13517565 0.16 ENST00000282091.1
ENST00000529816.1
 PTH
 parathyroid hormone
chr6_+_130339710 0.16 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr11_+_101918153 0.16 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
 C11orf70
 chromosome 11 open reading frame 70
chr17_-_39274606 0.15 ENST00000391413.2
 KRTAP4-11
 keratin associated protein 4-11
chr18_+_61254570 0.15 ENST00000344731.5
 SERPINB13
 serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr5_+_36608422 0.15 ENST00000381918.3
 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_61254534 0.15 ENST00000269489.5
 SERPINB13
 serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr5_+_110427983 0.14 ENST00000513710.2
ENST00000505303.1
 WDR36
 WD repeat domain 36
chr1_-_185597619 0.14 ENST00000608417.1
ENST00000436955.1
 GS1-204I12.1
 GS1-204I12.1
chr18_+_55888767 0.14 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_-_38956205 0.14 ENST00000306658.7
 KRT28
 keratin 28
chr14_+_56584414 0.14 ENST00000559044.1
 PELI2
 pellino E3 ubiquitin protein ligase family member 2
chr9_-_5339873 0.14 ENST00000223862.1
ENST00000223858.4
 RLN1
 relaxin 1
chr12_-_22063787 0.14 ENST00000544039.1
 ABCC9
 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr3_-_112565703 0.13 ENST00000488794.1
 CD200R1L
 CD200 receptor 1-like
chrX_-_50386648 0.13 ENST00000460112.3
 SHROOM4
 shroom family member 4
chr14_-_23652849 0.13 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
 SLC7A8
 solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr8_+_105235572 0.13 ENST00000523362.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr4_+_88896819 0.13 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
 SPP1
 secreted phosphoprotein 1
chr8_-_66474884 0.13 ENST00000520902.1
 CTD-3025N20.2
 CTD-3025N20.2
chr1_+_207226574 0.12 ENST00000367080.3
ENST00000367079.2
 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr19_+_9296279 0.12 ENST00000344248.2
 OR7D2
 olfactory receptor, family 7, subfamily D, member 2
chr3_-_112127981 0.12 ENST00000486726.2
 RP11-231E6.1
 RP11-231E6.1
chr6_+_125540951 0.12 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chrX_+_130192318 0.12 ENST00000370922.1
 ARHGAP36
 Rho GTPase activating protein 36
chr3_-_191000172 0.12 ENST00000427544.2
 UTS2B
 urotensin 2B
chr6_-_32908765 0.11 ENST00000416244.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr9_+_12693336 0.11 ENST00000381137.2
ENST00000388918.5
 TYRP1
 tyrosinase-related protein 1
chr17_-_4938712 0.11 ENST00000254853.5
ENST00000424747.1
 SLC52A1
 solute carrier family 52 (riboflavin transporter), member 1
chr9_-_95166884 0.11 ENST00000375561.5
 OGN
 osteoglycin
chr2_-_101925055 0.11 ENST00000295317.3
 RNF149
 ring finger protein 149
chr1_+_101003687 0.11 ENST00000315033.4
 GPR88
 G protein-coupled receptor 88
chr5_-_139726181 0.10 ENST00000507104.1
ENST00000230990.6
 HBEGF
 heparin-binding EGF-like growth factor
chr4_-_74486109 0.10 ENST00000395777.2
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr5_+_140227048 0.10 ENST00000532602.1
 PCDHA9
 protocadherin alpha 9
chr11_-_102651343 0.10 ENST00000279441.4
ENST00000539681.1
 MMP10
 matrix metallopeptidase 10 (stromelysin 2)
chr11_-_107729887 0.10 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr15_+_58430567 0.10 ENST00000536493.1
 AQP9
 aquaporin 9
chr1_-_197115818 0.10 ENST00000367409.4
ENST00000294732.7
 ASPM
 asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr9_-_95166841 0.10 ENST00000262551.4
 OGN
 osteoglycin
chr2_+_102615416 0.10 ENST00000393414.2
 IL1R2
 interleukin 1 receptor, type II
chr1_-_24741525 0.10 ENST00000374409.1
 STPG1
 sperm-tail PG-rich repeat containing 1
chr7_+_142982023 0.09 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
 TMEM139
 transmembrane protein 139
chr2_+_202047596 0.09 ENST00000286186.6
ENST00000360132.3
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr11_+_118398178 0.09 ENST00000302783.4
ENST00000539546.1
 TTC36
 tetratricopeptide repeat domain 36
chr2_-_89327228 0.09 ENST00000483158.1
 IGKV3-11
 immunoglobulin kappa variable 3-11
chr10_-_50970382 0.09 ENST00000419399.1
ENST00000432695.1
 OGDHL
 oxoglutarate dehydrogenase-like
chrX_-_130423200 0.09 ENST00000361420.3
 IGSF1
 immunoglobulin superfamily, member 1
chr16_+_12059050 0.09 ENST00000396495.3
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr12_+_26348246 0.09 ENST00000422622.2
 SSPN
 sarcospan
chr4_-_120243545 0.09 ENST00000274024.3
 FABP2
 fatty acid binding protein 2, intestinal
chr2_+_90077680 0.09 ENST00000390270.2
 IGKV3D-20
 immunoglobulin kappa variable 3D-20
chr17_-_40337470 0.09 ENST00000293330.1
 HCRT
 hypocretin (orexin) neuropeptide precursor
chr11_+_121447469 0.09 ENST00000532694.1
ENST00000534286.1
 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
chr10_-_50970322 0.09 ENST00000374103.4
 OGDHL
 oxoglutarate dehydrogenase-like
chr6_+_26365443 0.09 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
 BTN3A2
 butyrophilin, subfamily 3, member A2
chr9_+_108463234 0.09 ENST00000374688.1
 TMEM38B
 transmembrane protein 38B
chr4_-_74486347 0.09 ENST00000342081.3
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr4_-_39979576 0.09 ENST00000303538.8
ENST00000503396.1
 PDS5A
 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr1_+_70876926 0.08 ENST00000370938.3
ENST00000346806.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chr1_+_70876891 0.08 ENST00000411986.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chr9_-_117111222 0.08 ENST00000374079.4
 AKNA
 AT-hook transcription factor
chr15_+_94899183 0.08 ENST00000557742.1
 MCTP2
 multiple C2 domains, transmembrane 2
chr17_-_73663245 0.08 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
 RECQL5
 RecQ protein-like 5
chr8_+_107738343 0.08 ENST00000521592.1
 OXR1
 oxidation resistance 1
chr15_+_35270552 0.08 ENST00000391457.2
 AC114546.1
 HCG37415; PRO1914; Uncharacterized protein
chr4_+_71200681 0.08 ENST00000273936.5
 CABS1
 calcium-binding protein, spermatid-specific 1
chr14_+_21387508 0.08 ENST00000555624.1
 RP11-84C10.2
 RP11-84C10.2
chr10_+_5238793 0.08 ENST00000263126.1
 AKR1C4
 aldo-keto reductase family 1, member C4
chr17_-_48785216 0.08 ENST00000285243.6
 ANKRD40
 ankyrin repeat domain 40
chr17_-_5321549 0.08 ENST00000572809.1
 NUP88
 nucleoporin 88kDa
chr3_-_185538849 0.08 ENST00000421047.2
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr4_+_77356248 0.08 ENST00000296043.6
 SHROOM3
 shroom family member 3
chr2_-_134326009 0.08 ENST00000409261.1
ENST00000409213.1
 NCKAP5
 NCK-associated protein 5
chr11_+_55594695 0.08 ENST00000378397.1
 OR5L2
 olfactory receptor, family 5, subfamily L, member 2
chr12_+_8276495 0.08 ENST00000546339.1
 CLEC4A
 C-type lectin domain family 4, member A
chr12_-_15114658 0.08 ENST00000542276.1
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr21_+_43619796 0.08 ENST00000398457.2
 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
chr19_-_3557570 0.08 ENST00000355415.2
 MFSD12
 major facilitator superfamily domain containing 12
chr10_+_695888 0.08 ENST00000441152.2
 PRR26
 proline rich 26
chr16_+_58010339 0.08 ENST00000290871.5
ENST00000441824.2
 TEPP
 testis, prostate and placenta expressed
chr14_-_67878917 0.08 ENST00000216446.4
 PLEK2
 pleckstrin 2
chr20_-_50418947 0.08 ENST00000371539.3
 SALL4
 spalt-like transcription factor 4
chr12_+_28410128 0.08 ENST00000381259.1
ENST00000381256.1
 CCDC91
 coiled-coil domain containing 91
chr17_+_43238438 0.08 ENST00000593138.1
ENST00000586681.1
 HEXIM2
 hexamethylene bis-acetamide inducible 2
chr14_-_78083112 0.08 ENST00000216484.2
 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
chr20_-_50418972 0.08 ENST00000395997.3
 SALL4
 spalt-like transcription factor 4
chr6_+_134758827 0.07 ENST00000431422.1
 LINC01010
 long intergenic non-protein coding RNA 1010
chr11_+_18154059 0.07 ENST00000531264.1
 MRGPRX3
 MAS-related GPR, member X3
chr3_-_33686743 0.07 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr5_-_82969405 0.07 ENST00000510978.1
 HAPLN1
 hyaluronan and proteoglycan link protein 1
chr20_-_50419055 0.07 ENST00000217086.4
 SALL4
 spalt-like transcription factor 4
chr4_+_70861647 0.07 ENST00000246895.4
ENST00000381060.2
 STATH
 statherin
chr5_-_41213607 0.07 ENST00000337836.5
ENST00000433294.1
 C6
 complement component 6
chr12_-_15114603 0.07 ENST00000228945.4
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chrX_-_15332665 0.07 ENST00000537676.1
ENST00000344384.4
 ASB11
 ankyrin repeat and SOCS box containing 11
chr14_-_21566731 0.07 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr22_-_29107919 0.07 ENST00000434810.1
ENST00000456369.1
 CHEK2
 checkpoint kinase 2
chr16_+_82090028 0.07 ENST00000568090.1
 HSD17B2
 hydroxysteroid (17-beta) dehydrogenase 2
chr11_-_124190184 0.07 ENST00000357438.2
 OR8D2
 olfactory receptor, family 8, subfamily D, member 2
chr21_-_31588365 0.07 ENST00000399899.1
 CLDN8
 claudin 8
chr3_+_147795932 0.07 ENST00000490465.1
 RP11-639B1.1
 RP11-639B1.1
chr16_+_15489603 0.07 ENST00000568766.1
ENST00000287594.7
 RP11-1021N1.1
MPV17L
 Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr9_+_130911770 0.07 ENST00000372998.1
 LCN2
 lipocalin 2
chr18_-_74839891 0.07 ENST00000581878.1
 MBP
 myelin basic protein
chr5_+_89770664 0.07 ENST00000503973.1
ENST00000399107.1
 POLR3G
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr3_+_97887544 0.07 ENST00000356526.2
 OR5H15
 olfactory receptor, family 5, subfamily H, member 15
chr21_-_31588338 0.07 ENST00000286809.1
 CLDN8
 claudin 8
chr4_+_71458012 0.07 ENST00000449493.2
 AMBN
 ameloblastin (enamel matrix protein)
chr10_-_98031265 0.07 ENST00000224337.5
ENST00000371176.2
 BLNK
 B-cell linker
chr1_+_12834984 0.07 ENST00000357726.4
 PRAMEF12
 PRAME family member 12
chr10_-_47151341 0.07 ENST00000422732.2
 LINC00842
 long intergenic non-protein coding RNA 842
chrX_+_144908928 0.07 ENST00000408967.2
 TMEM257
 transmembrane protein 257
chr2_+_90273679 0.07 ENST00000423080.2
 IGKV3D-7
 immunoglobulin kappa variable 3D-7
chr12_+_20963632 0.06 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr4_+_80584903 0.06 ENST00000506460.1
 RP11-452C8.1
 RP11-452C8.1
chr5_+_89770696 0.06 ENST00000504930.1
ENST00000514483.1
 POLR3G
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr11_-_128894053 0.06 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr10_-_135379074 0.06 ENST00000303903.6
 SYCE1
 synaptonemal complex central element protein 1
chr21_+_17442799 0.06 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr3_-_151047327 0.06 ENST00000325602.5
 P2RY13
 purinergic receptor P2Y, G-protein coupled, 13
chr17_-_10372875 0.06 ENST00000255381.2
 MYH4
 myosin, heavy chain 4, skeletal muscle
chr16_-_30122717 0.06 ENST00000566613.1
 GDPD3
 glycerophosphodiester phosphodiesterase domain containing 3
chr3_-_33686925 0.06 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
 CLASP2
 cytoplasmic linker associated protein 2
chr16_-_28621312 0.06 ENST00000314752.7
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_-_98235962 0.06 ENST00000513873.1
 CLDND1
 claudin domain containing 1
chr17_-_27418537 0.06 ENST00000408971.2
 TIAF1
 TGFB1-induced anti-apoptotic factor 1
chrX_+_150565653 0.06 ENST00000330374.6
 VMA21
 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr4_-_46911223 0.06 ENST00000396533.1
 COX7B2
 cytochrome c oxidase subunit VIIb2
chr11_-_104827425 0.06 ENST00000393150.3
 CASP4
 caspase 4, apoptosis-related cysteine peptidase
chr12_+_7014126 0.06 ENST00000415834.1
ENST00000436789.1
 LRRC23
 leucine rich repeat containing 23
chr7_-_111032971 0.06 ENST00000450877.1
 IMMP2L
 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr4_+_86525299 0.06 ENST00000512201.1
 ARHGAP24
 Rho GTPase activating protein 24
chr5_-_141249154 0.06 ENST00000357517.5
ENST00000536585.1
 PCDH1
 protocadherin 1
chr4_-_79860506 0.06 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
 PAQR3
 progestin and adipoQ receptor family member III
chr2_+_201754050 0.06 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
 NIF3L1
 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr9_+_130911723 0.06 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
 LCN2
 lipocalin 2
chr2_+_201754135 0.06 ENST00000409357.1
ENST00000409129.2
 NIF3L1
 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr12_-_112123524 0.06 ENST00000327551.6
 BRAP
 BRCA1 associated protein
chr11_+_65554493 0.06 ENST00000335987.3
 OVOL1
 ovo-like zinc finger 1
chr15_+_49462434 0.06 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
 GALK2
 galactokinase 2
chr10_+_5454505 0.06 ENST00000355029.4
 NET1
 neuroepithelial cell transforming 1
chr3_-_143567262 0.06 ENST00000474151.1
ENST00000316549.6
 SLC9A9
 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr1_+_75198828 0.06 ENST00000457880.2
ENST00000370867.3
ENST00000421739.2
 TYW3
 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr4_+_41614909 0.06 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
 LIMCH1
 LIM and calponin homology domains 1
chr4_+_119809984 0.06 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
 SYNPO2
 synaptopodin 2
chr7_+_129906660 0.06 ENST00000222481.4
 CPA2
 carboxypeptidase A2 (pancreatic)
chr15_-_54051831 0.05 ENST00000557913.1
ENST00000360509.5
 WDR72
 WD repeat domain 72
chr5_-_93077293 0.05 ENST00000510627.4
 POU5F2
 POU domain class 5, transcription factor 2
chr7_-_37026108 0.05 ENST00000396045.3
 ELMO1
 engulfment and cell motility 1
chr12_+_26348429 0.05 ENST00000242729.2
 SSPN
 sarcospan
chr10_-_98031310 0.05 ENST00000427367.2
ENST00000413476.2
 BLNK
 B-cell linker
chr1_+_86934526 0.05 ENST00000394711.1
 CLCA1
 chloride channel accessory 1
chr2_+_228735763 0.05 ENST00000373666.2
 DAW1
 dynein assembly factor with WDR repeat domains 1
chr19_+_15160130 0.05 ENST00000427043.3
 CASP14
 caspase 14, apoptosis-related cysteine peptidase
chr20_-_4721314 0.05 ENST00000418528.1
ENST00000326539.2
ENST00000423718.2
 PRNT
 prion protein (testis specific)
chr1_+_107683644 0.05 ENST00000370067.1
 NTNG1
 netrin G1
chrX_+_49687267 0.05 ENST00000376091.3
 CLCN5
 chloride channel, voltage-sensitive 5
chr7_+_107224364 0.05 ENST00000491150.1
 BCAP29
 B-cell receptor-associated protein 29
chr10_+_696000 0.05 ENST00000381489.5
 PRR26
 proline rich 26
chr1_+_107683436 0.05 ENST00000370068.1
 NTNG1
 netrin G1
chr1_-_222763101 0.05 ENST00000391883.2
ENST00000366890.1
 TAF1A
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.4 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.2 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.2 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.0 GO:1902908 regulation of melanosome transport(GO:1902908) regulation of melanosome organization(GO:1903056)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.0 GO:0072200 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.0 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.0 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.0 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.0 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.0 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules