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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for DMBX1

Z-value: 0.59

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Transcription factors associated with DMBX1

Gene Symbol Gene ID Gene Info
DMBX1
ENSG00000197587.6 DMBX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DMBX1hg19_v2_chr1_+_46972668_469726690.108.1e-01Click!

Activity profile of DMBX1 motif

Sorted Z-values of DMBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DMBX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_118187379 0.51 ENST00000369230.3
 PNLIPRP3
 pancreatic lipase-related protein 3
chr18_+_29027696 0.46 ENST00000257189.4
 DSG3
 desmoglein 3
chrX_-_102565932 0.41 ENST00000372674.1
ENST00000372677.3
 BEX2
 brain expressed X-linked 2
chr2_-_70780770 0.37 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA
 transforming growth factor, alpha
chr2_-_70780572 0.36 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr17_-_4643114 0.36 ENST00000293778.6
 CXCL16
 chemokine (C-X-C motif) ligand 16
chr8_-_125577940 0.33 ENST00000519168.1
ENST00000395508.2
 MTSS1
 metastasis suppressor 1
chrX_-_32173579 0.28 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
 DMD
 dystrophin
chr12_+_7941989 0.15 ENST00000229307.4
 NANOG
 Nanog homeobox
chr6_+_89791507 0.14 ENST00000354922.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr11_-_36619771 0.13 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
 RAG2
 recombination activating gene 2
chr19_-_6459746 0.12 ENST00000301454.4
ENST00000334510.5
 SLC25A23
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr3_+_49058444 0.12 ENST00000326925.6
ENST00000395458.2
 NDUFAF3
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_+_130339710 0.12 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr7_+_1727755 0.12 ENST00000424383.2
 ELFN1
 extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr3_+_49057876 0.11 ENST00000326912.4
 NDUFAF3
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_-_94586651 0.10 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_140586922 0.10 ENST00000265498.1
ENST00000506797.1
 MGST2
 microsomal glutathione S-transferase 2
chr11_+_61248583 0.10 ENST00000432063.2
ENST00000338608.2
 PPP1R32
 protein phosphatase 1, regulatory subunit 32
chr6_-_111927062 0.09 ENST00000359831.4
 TRAF3IP2
 TRAF3 interacting protein 2
chr20_+_31805131 0.08 ENST00000375454.3
ENST00000375452.3
 BPIFA3
 BPI fold containing family A, member 3
chr3_+_188664988 0.08 ENST00000433971.1
 TPRG1
 tumor protein p63 regulated 1
chr15_-_85201779 0.08 ENST00000360476.3
ENST00000394588.3
 NMB
 neuromedin B
chr20_-_43729750 0.08 ENST00000537075.1
ENST00000306117.1
 KCNS1
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr15_+_74165945 0.08 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
 TBC1D21
 TBC1 domain family, member 21
chr10_+_74451883 0.07 ENST00000373053.3
ENST00000357157.6
 MCU
 mitochondrial calcium uniporter
chr20_+_34556488 0.07 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
 CNBD2
 cyclic nucleotide binding domain containing 2
chr3_-_11685345 0.07 ENST00000430365.2
 VGLL4
 vestigial like 4 (Drosophila)
chr17_+_4643300 0.07 ENST00000433935.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr9_-_21995249 0.07 ENST00000494262.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr17_+_4643337 0.07 ENST00000592813.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr1_+_120839005 0.06 ENST00000369390.3
ENST00000452190.1
 FAM72B
 family with sequence similarity 72, member B
chr3_+_136649311 0.06 ENST00000469404.1
ENST00000467911.1
 NCK1
 NCK adaptor protein 1
chr6_-_138893661 0.06 ENST00000427025.2
 NHSL1
 NHS-like 1
chr1_-_143913143 0.06 ENST00000400889.1
 FAM72D
 family with sequence similarity 72, member D
chr1_+_206138457 0.06 ENST00000367128.3
ENST00000431655.2
 FAM72A
 family with sequence similarity 72, member A
chr9_-_21995300 0.06 ENST00000498628.2
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr2_-_165812028 0.06 ENST00000303735.4
 SLC38A11
 solute carrier family 38, member 11
chr19_+_36157715 0.05 ENST00000379013.2
ENST00000222275.2
 UPK1A
 uroplakin 1A
chr2_-_165811983 0.05 ENST00000409058.1
ENST00000409149.3
 SLC38A11
 solute carrier family 38, member 11
chr12_+_115800817 0.05 ENST00000547948.1
 RP11-116D17.1
 HCG2038717; Uncharacterized protein
chr12_-_21487829 0.05 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
 SLCO1A2
 solute carrier organic anion transporter family, member 1A2
chr9_-_21994344 0.05 ENST00000530628.2
ENST00000361570.3
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr7_-_135412925 0.04 ENST00000354042.4
 SLC13A4
 solute carrier family 13 (sodium/sulfate symporter), member 4
chr12_-_118628350 0.04 ENST00000537952.1
ENST00000537822.1
 TAOK3
 TAO kinase 3
chr19_+_46001697 0.04 ENST00000451287.2
ENST00000324688.4
 PPM1N
 protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr9_-_21994597 0.04 ENST00000579755.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr4_+_169552748 0.04 ENST00000504519.1
ENST00000512127.1
 PALLD
 palladin, cytoskeletal associated protein
chr2_-_165811756 0.04 ENST00000409662.1
 SLC38A11
 solute carrier family 38, member 11
chr6_-_26250835 0.03 ENST00000446824.2
 HIST1H3F
 histone cluster 1, H3f
chr15_+_63413990 0.03 ENST00000261893.4
 LACTB
 lactamase, beta
chr16_-_20338748 0.03 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
 GP2
 glycoprotein 2 (zymogen granule membrane)
chr17_-_38859996 0.03 ENST00000264651.2
 KRT24
 keratin 24
chr19_-_17186229 0.03 ENST00000253669.5
ENST00000448593.2
 HAUS8
 HAUS augmin-like complex, subunit 8
chr17_+_68100989 0.03 ENST00000585558.1
ENST00000392670.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr19_+_17448348 0.03 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
 GTPBP3
 GTP binding protein 3 (mitochondrial)
chr2_+_73461410 0.03 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
 CCT7
 chaperonin containing TCP1, subunit 7 (eta)
chr2_+_73461364 0.03 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
 CCT7
 chaperonin containing TCP1, subunit 7 (eta)
chr17_+_60536002 0.03 ENST00000582809.1
 TLK2
 tousled-like kinase 2
chr17_-_12921270 0.03 ENST00000578071.1
ENST00000426905.3
ENST00000395962.2
ENST00000583371.1
ENST00000338034.4
 ELAC2
 elaC ribonuclease Z 2
chr1_-_28384598 0.03 ENST00000373864.1
 EYA3
 eyes absent homolog 3 (Drosophila)
chr12_-_56321649 0.02 ENST00000454792.2
ENST00000408946.2
 WIBG
 within bgcn homolog (Drosophila)
chr11_+_124055923 0.02 ENST00000318666.6
 OR10D3
 olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr1_+_109756523 0.02 ENST00000234677.2
ENST00000369923.4
 SARS
 seryl-tRNA synthetase
chr19_+_41284121 0.02 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
 RAB4B
 RAB4B, member RAS oncogene family
chr2_-_14541060 0.02 ENST00000418420.1
ENST00000417751.1
 LINC00276
 long intergenic non-protein coding RNA 276
chr4_+_619386 0.02 ENST00000496514.1
 PDE6B
 phosphodiesterase 6B, cGMP-specific, rod, beta
chr11_-_45940343 0.02 ENST00000532681.1
 PEX16
 peroxisomal biogenesis factor 16
chr12_-_56321397 0.02 ENST00000557259.1
ENST00000549939.1
 WIBG
 within bgcn homolog (Drosophila)
chr14_+_22265444 0.02 ENST00000390430.2
 TRAV8-1
 T cell receptor alpha variable 8-1
chr19_-_17185848 0.01 ENST00000593360.1
 HAUS8
 HAUS augmin-like complex, subunit 8
chr21_+_18811205 0.01 ENST00000440664.1
 C21orf37
 chromosome 21 open reading frame 37
chr10_-_35104185 0.01 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
 PARD3
 par-3 family cell polarity regulator
chrX_+_72062617 0.01 ENST00000440247.1
 DMRTC1B
 DMRT-like family C1B
chr4_-_54232144 0.01 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
 SCFD2
 sec1 family domain containing 2
chr3_-_149470229 0.01 ENST00000473414.1
 COMMD2
 COMM domain containing 2
chr3_-_10362725 0.01 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
 SEC13
 SEC13 homolog (S. cerevisiae)
chrX_-_71792477 0.01 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
 HDAC8
 histone deacetylase 8
chr1_-_13452656 0.01 ENST00000376132.3
 PRAMEF13
 PRAME family member 13
chr17_-_39324424 0.01 ENST00000391356.2
 KRTAP4-3
 keratin associated protein 4-3
chr12_+_54718904 0.00 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1
 coatomer protein complex, subunit zeta 1
chr18_-_35145593 0.00 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
 CELF4
 CUGBP, Elav-like family member 4
chr3_-_179692042 0.00 ENST00000468741.1
 PEX5L
 peroxisomal biogenesis factor 5-like
chr15_+_63414760 0.00 ENST00000557972.1
 LACTB
 lactamase, beta
chr12_-_110937351 0.00 ENST00000552130.2
 VPS29
 vacuolar protein sorting 29 homolog (S. cerevisiae)
chr17_+_48911942 0.00 ENST00000426127.1
 WFIKKN2
 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr8_-_110656995 0.00 ENST00000276646.9
ENST00000533065.1
 SYBU
 syntabulin (syntaxin-interacting)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins