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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for E2F2_E2F5

Z-value: 0.14

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
E2F2
ENSG00000007968.6 E2F2
E2F5
ENSG00000133740.6 E2F5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg19_v2_chr1_-_23857698_238577330.648.8e-02Click!
E2F5hg19_v2_chr8_+_86121448_86121494-0.502.1e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_36235529 2.27 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
 CLSPN
 claspin
chr8_-_124408652 2.22 ENST00000287394.5
 ATAD2
 ATPase family, AAA domain containing 2
chr11_-_19263145 1.63 ENST00000532666.1
ENST00000527884.1
 E2F8
 E2F transcription factor 8
chr1_-_36235559 1.61 ENST00000251195.5
 CLSPN
 claspin
chr16_-_3030283 1.50 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
 PKMYT1
 protein kinase, membrane associated tyrosine/threonine 1
chr11_-_19262486 1.49 ENST00000250024.4
 E2F8
 E2F transcription factor 8
chr2_+_27498289 1.45 ENST00000296097.3
ENST00000420191.1
 DNAJC5G
 DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr16_-_3030407 1.40 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
 PKMYT1
 protein kinase, membrane associated tyrosine/threonine 1
chr2_+_27498331 1.30 ENST00000402462.1
ENST00000404433.1
ENST00000406962.1
 DNAJC5G
 DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr4_+_55524085 1.20 ENST00000412167.2
ENST00000288135.5
 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr3_-_48229846 1.19 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
 CDC25A
 cell division cycle 25A
chr13_+_32889605 1.16 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
 BRCA2
 breast cancer 2, early onset
chr20_-_32274179 1.05 ENST00000343380.5
 E2F1
 E2F transcription factor 1
chr17_+_29158962 1.03 ENST00000321990.4
 ATAD5
 ATPase family, AAA domain containing 5
chr10_+_13203543 1.03 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
 MCM10
 minichromosome maintenance complex component 10
chr20_-_35724388 1.00 ENST00000344359.3
ENST00000373664.3
 RBL1
 retinoblastoma-like 1 (p107)
chr1_+_212208919 0.99 ENST00000366991.4
ENST00000542077.1
 DTL
 denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr1_-_23857698 0.96 ENST00000361729.2
 E2F2
 E2F transcription factor 2
chr11_+_62623544 0.96 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
 SLC3A2
 solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623621 0.95 ENST00000535296.1
 SLC3A2
 solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623512 0.95 ENST00000377892.1
 SLC3A2
 solute carrier family 3 (amino acid transporter heavy chain), member 2
chr15_+_40987327 0.93 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
 RAD51
 RAD51 recombinase
chr15_+_32907691 0.91 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
 ARHGAP11A
 Rho GTPase activating protein 11A
chr1_-_47779762 0.90 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
 STIL
 SCL/TAL1 interrupting locus
chr2_+_17935119 0.84 ENST00000317402.7
 GEN1
 GEN1 Holliday junction 5' flap endonuclease
chr2_+_10262857 0.84 ENST00000304567.5
 RRM2
 ribonucleotide reductase M2
chr20_-_5931109 0.80 ENST00000203001.2
 TRMT6
 tRNA methyltransferase 6 homolog (S. cerevisiae)
chr20_-_5931051 0.79 ENST00000453074.2
 TRMT6
 tRNA methyltransferase 6 homolog (S. cerevisiae)
chr2_+_17935383 0.78 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
 GEN1
 GEN1 Holliday junction 5' flap endonuclease
chr19_-_10305752 0.76 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
 DNMT1
 DNA (cytosine-5-)-methyltransferase 1
chr3_+_44803209 0.73 ENST00000326047.4
 KIF15
 kinesin family member 15
chr20_+_5931497 0.72 ENST00000378886.2
ENST00000265187.4
 MCM8
 minichromosome maintenance complex component 8
chr13_-_110438914 0.71 ENST00000375856.3
 IRS2
 insulin receptor substrate 2
chr2_-_235405679 0.69 ENST00000390645.2
 ARL4C
 ADP-ribosylation factor-like 4C
chr13_-_26625169 0.68 ENST00000319420.3
 SHISA2
 shisa family member 2
chr20_+_5931275 0.66 ENST00000378896.3
ENST00000378883.1
 MCM8
 minichromosome maintenance complex component 8
chr10_+_62538089 0.66 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
 CDK1
 cyclin-dependent kinase 1
chr10_+_62538248 0.63 ENST00000448257.2
 CDK1
 cyclin-dependent kinase 1
chr8_+_94929168 0.62 ENST00000518107.1
ENST00000396200.3
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_-_133263893 0.62 ENST00000535270.1
ENST00000320574.5
 POLE
 polymerase (DNA directed), epsilon, catalytic subunit
chr8_+_94929077 0.61 ENST00000297598.4
ENST00000520614.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_120612240 0.60 ENST00000256646.2
 NOTCH2
 notch 2
chr7_-_99699538 0.56 ENST00000343023.6
ENST00000303887.5
 MCM7
 minichromosome maintenance complex component 7
chr10_+_112327425 0.55 ENST00000361804.4
 SMC3
 structural maintenance of chromosomes 3
chr8_+_94929110 0.54 ENST00000520728.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_-_77459306 0.53 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
 E2F7
 E2F transcription factor 7
chr14_+_51706886 0.52 ENST00000457354.2
 TMX1
 thioredoxin-related transmembrane protein 1
chr2_-_17935059 0.51 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
 SMC6
 structural maintenance of chromosomes 6
chrX_+_48554986 0.51 ENST00000376687.3
ENST00000453214.2
 SUV39H1
 suppressor of variegation 3-9 homolog 1 (Drosophila)
chr3_+_10068095 0.50 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
 FANCD2
 Fanconi anemia, complementation group D2
chr2_-_232329186 0.50 ENST00000322723.4
 NCL
 nucleolin
chr6_+_24775153 0.50 ENST00000356509.3
ENST00000230056.3
 GMNN
 geminin, DNA replication inhibitor
chr4_+_30721968 0.48 ENST00000361762.2
 PCDH7
 protocadherin 7
chr11_-_118966167 0.47 ENST00000530167.1
 H2AFX
 H2A histone family, member X
chr5_-_36152031 0.45 ENST00000296603.4
 LMBRD2
 LMBR1 domain containing 2
chr10_+_73724123 0.44 ENST00000373115.4
 CHST3
 carbohydrate (chondroitin 6) sulfotransferase 3
chr6_+_116575329 0.44 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
 DSE
RP3-486I3.7
 dermatan sulfate epimerase
RP3-486I3.7
chr4_+_154265784 0.44 ENST00000240488.3
 MND1
 meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr21_-_30365136 0.42 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
 LTN1
 listerin E3 ubiquitin protein ligase 1
chr5_-_79950775 0.42 ENST00000439211.2
 DHFR
 dihydrofolate reductase
chrX_+_24711997 0.42 ENST00000379068.3
ENST00000379059.3
 POLA1
 polymerase (DNA directed), alpha 1, catalytic subunit
chr7_-_148581251 0.41 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
 EZH2
 enhancer of zeste homolog 2 (Drosophila)
chr22_-_38966172 0.41 ENST00000216024.2
 DMC1
 DNA meiotic recombinase 1
chr20_+_25388293 0.41 ENST00000262460.4
ENST00000429262.2
 GINS1
 GINS complex subunit 1 (Psf1 homolog)
chr2_-_47168850 0.40 ENST00000409207.1
 MCFD2
 multiple coagulation factor deficiency 2
chr7_-_158497431 0.40 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
 NCAPG2
 non-SMC condensin II complex, subunit G2
chr6_-_52149475 0.40 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
 MCM3
 minichromosome maintenance complex component 3
chr7_+_120590803 0.39 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
 ING3
 inhibitor of growth family, member 3
chr10_+_96305535 0.39 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
 HELLS
 helicase, lymphoid-specific
chr9_-_35080013 0.39 ENST00000378643.3
 FANCG
 Fanconi anemia, complementation group G
chr7_-_148581360 0.39 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
 EZH2
 enhancer of zeste homolog 2 (Drosophila)
chr12_-_12849073 0.38 ENST00000332427.2
ENST00000540796.1
 GPR19
 G protein-coupled receptor 19
chr1_-_54303934 0.38 ENST00000537333.1
 NDC1
 NDC1 transmembrane nucleoporin
chr8_-_15095832 0.37 ENST00000382080.1
 SGCZ
 sarcoglycan, zeta
chr15_+_80987617 0.37 ENST00000258884.4
ENST00000558464.1
 ABHD17C
 abhydrolase domain containing 17C
chr11_-_95522907 0.37 ENST00000358780.5
ENST00000542135.1
 FAM76B
 family with sequence similarity 76, member B
chr4_-_130014609 0.36 ENST00000511426.1
 SCLT1
 sodium channel and clathrin linker 1
chr16_+_28962128 0.36 ENST00000564978.1
ENST00000320805.4
 NFATC2IP
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr5_+_79950463 0.36 ENST00000265081.6
 MSH3
 mutS homolog 3
chr14_-_50154921 0.35 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
 POLE2
 polymerase (DNA directed), epsilon 2, accessory subunit
chr11_-_85376121 0.35 ENST00000527447.1
 CREBZF
 CREB/ATF bZIP transcription factor
chr4_+_178230985 0.35 ENST00000264596.3
 NEIL3
 nei endonuclease VIII-like 3 (E. coli)
chr1_+_179262905 0.35 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
 SOAT1
 sterol O-acyltransferase 1
chr4_-_130014729 0.35 ENST00000281142.5
ENST00000434680.1
 SCLT1
 sodium channel and clathrin linker 1
chr4_-_130014705 0.34 ENST00000503401.1
 SCLT1
 sodium channel and clathrin linker 1
chr6_+_24775641 0.34 ENST00000378054.2
ENST00000476555.1
 GMNN
 geminin, DNA replication inhibitor
chr2_-_55277692 0.34 ENST00000394611.2
 RTN4
 reticulon 4
chr2_+_16080659 0.34 ENST00000281043.3
 MYCN
 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr10_+_103912137 0.34 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
 NOLC1
 nucleolar and coiled-body phosphoprotein 1
chr1_-_100598444 0.34 ENST00000535161.1
ENST00000287482.5
 SASS6
 spindle assembly 6 homolog (C. elegans)
chr7_-_94285511 0.34 ENST00000265735.7
 SGCE
 sarcoglycan, epsilon
chr15_-_64673665 0.34 ENST00000300035.4
 KIAA0101
 KIAA0101
chr2_-_55277654 0.33 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
 RTN4
 reticulon 4
chr7_+_6048856 0.33 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
 AIMP2
 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr5_+_36876833 0.33 ENST00000282516.8
ENST00000448238.2
 NIPBL
 Nipped-B homolog (Drosophila)
chr13_-_80915059 0.33 ENST00000377104.3
 SPRY2
 sprouty homolog 2 (Drosophila)
chrX_+_100353153 0.32 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
 CENPI
 centromere protein I
chrX_+_123095546 0.32 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
 STAG2
 stromal antigen 2
chrX_-_53449593 0.32 ENST00000375340.6
ENST00000322213.4
 SMC1A
 structural maintenance of chromosomes 1A
chr15_-_66649010 0.32 ENST00000367709.4
ENST00000261881.4
 TIPIN
 TIMELESS interacting protein
chrX_-_53711064 0.31 ENST00000342160.3
ENST00000446750.1
 HUWE1
 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
chr2_-_47168906 0.31 ENST00000444761.2
ENST00000409147.1
 MCFD2
 multiple coagulation factor deficiency 2
chr17_+_74380683 0.31 ENST00000592299.1
ENST00000590959.1
ENST00000323374.4
 SPHK1
 sphingosine kinase 1
chr2_-_139537918 0.31 ENST00000272641.3
 NXPH2
 neurexophilin 2
chr16_+_3019552 0.31 ENST00000572687.1
 PAQR4
 progestin and adipoQ receptor family member IV
chr9_-_99180597 0.30 ENST00000375256.4
 ZNF367
 zinc finger protein 367
chr9_+_504674 0.30 ENST00000382297.2
 KANK1
 KN motif and ankyrin repeat domains 1
chr7_-_94285472 0.30 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
 SGCE
 sarcoglycan, epsilon
chr2_+_174219548 0.29 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
 CDCA7
 cell division cycle associated 7
chr6_-_17706618 0.29 ENST00000262077.2
ENST00000537253.1
 NUP153
 nucleoporin 153kDa
chr10_+_103911926 0.28 ENST00000605788.1
ENST00000405356.1
 NOLC1
 nucleolar and coiled-body phosphoprotein 1
chr16_+_3019246 0.28 ENST00000318782.8
ENST00000293978.8
 PAQR4
 progestin and adipoQ receptor family member IV
chr5_-_79950371 0.28 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
 DHFR
 dihydrofolate reductase
chr6_+_37137939 0.28 ENST00000373509.5
 PIM1
 pim-1 oncogene
chr22_+_31031639 0.27 ENST00000343605.4
ENST00000300385.8
 SLC35E4
 solute carrier family 35, member E4
chr2_-_55277512 0.27 ENST00000402434.2
 RTN4
 reticulon 4
chr2_-_55277436 0.27 ENST00000354474.6
 RTN4
 reticulon 4
chr1_+_240255166 0.27 ENST00000319653.9
 FMN2
 formin 2
chr8_-_120868078 0.26 ENST00000313655.4
 DSCC1
 DNA replication and sister chromatid cohesion 1
chr5_+_175875349 0.26 ENST00000261942.6
 FAF2
 Fas associated factor family member 2
chr9_+_106856831 0.25 ENST00000303219.8
ENST00000374787.3
 SMC2
 structural maintenance of chromosomes 2
chr7_+_116593568 0.25 ENST00000446490.1
 ST7
 suppression of tumorigenicity 7
chr3_-_136471204 0.25 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
 STAG1
 stromal antigen 1
chr7_-_94285402 0.25 ENST00000428696.2
ENST00000445866.2
 SGCE
 sarcoglycan, epsilon
chr1_+_145209092 0.25 ENST00000362074.6
ENST00000344859.3
 NOTCH2NL
 notch 2 N-terminal like
chr10_+_102672712 0.24 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
 FAM178A
 family with sequence similarity 178, member A
chr11_-_74442430 0.24 ENST00000376332.3
 CHRDL2
 chordin-like 2
chr3_-_133380731 0.24 ENST00000260810.5
 TOPBP1
 topoisomerase (DNA) II binding protein 1
chr19_+_58694396 0.23 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
 ZNF274
 zinc finger protein 274
chr1_+_151043070 0.23 ENST00000368918.3
ENST00000368917.1
 GABPB2
 GA binding protein transcription factor, beta subunit 2
chr1_-_229694406 0.23 ENST00000344517.4
 ABCB10
 ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr15_+_41221536 0.23 ENST00000249749.5
 DLL4
 delta-like 4 (Drosophila)
chr1_-_243418621 0.23 ENST00000366544.1
ENST00000366543.1
 CEP170
 centrosomal protein 170kDa
chr4_+_71859156 0.22 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
 DCK
 deoxycytidine kinase
chr19_+_50094866 0.22 ENST00000418929.2
 PRR12
 proline rich 12
chr1_+_100598691 0.22 ENST00000370143.1
ENST00000370141.2
 TRMT13
 tRNA methyltransferase 13 homolog (S. cerevisiae)
chr7_+_116593292 0.22 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
 ST7
 suppression of tumorigenicity 7
chr13_+_45694583 0.22 ENST00000340473.6
 GTF2F2
 general transcription factor IIF, polypeptide 2, 30kDa
chr11_-_95522639 0.21 ENST00000536839.1
 FAM76B
 family with sequence similarity 76, member B
chr7_+_120591170 0.21 ENST00000431467.1
 ING3
 inhibitor of growth family, member 3
chr3_+_10857885 0.21 ENST00000254488.2
ENST00000454147.1
 SLC6A11
 solute carrier family 6 (neurotransmitter transporter), member 11
chr3_-_169381183 0.21 ENST00000494292.1
 MECOM
 MDS1 and EVI1 complex locus
chr9_+_106856541 0.21 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
 SMC2
 structural maintenance of chromosomes 2
chr3_-_49893958 0.21 ENST00000482243.1
ENST00000331456.2
ENST00000469027.1
 TRAIP
 TRAF interacting protein
chr4_+_148538517 0.21 ENST00000296582.3
ENST00000508208.1
 TMEM184C
 transmembrane protein 184C
chr7_+_26241325 0.21 ENST00000456948.1
ENST00000409747.1
 CBX3
 chromobox homolog 3
chr7_+_99933730 0.21 ENST00000610247.1
 PILRB
 paired immunoglobin-like type 2 receptor beta
chr22_+_35796056 0.21 ENST00000216122.4
 MCM5
 minichromosome maintenance complex component 5
chr9_-_140484917 0.20 ENST00000298585.2
 ZMYND19
 zinc finger, MYND-type containing 19
chr21_-_33104367 0.20 ENST00000286835.7
ENST00000399804.1
 SCAF4
 SR-related CTD-associated factor 4
chr1_-_243418344 0.20 ENST00000366542.1
 CEP170
 centrosomal protein 170kDa
chrX_-_45710920 0.20 ENST00000456532.1
 RP5-1158E12.3
 RP5-1158E12.3
chr8_+_48873479 0.19 ENST00000262105.2
 MCM4
 minichromosome maintenance complex component 4
chr6_+_31707725 0.19 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
 MSH5
 mutS homolog 5
chrX_-_75005054 0.19 ENST00000373359.2
 MAGEE2
 melanoma antigen family E, 2
chr1_+_86046433 0.19 ENST00000451137.2
 CYR61
 cysteine-rich, angiogenic inducer, 61
chr3_-_52719810 0.19 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
 PBRM1
 polybromo 1
chr8_+_48873453 0.19 ENST00000523944.1
 MCM4
 minichromosome maintenance complex component 4
chr8_+_95565947 0.19 ENST00000523011.1
 RP11-267M23.4
 RP11-267M23.4
chr7_+_116593433 0.19 ENST00000323984.3
ENST00000393449.1
 ST7
 suppression of tumorigenicity 7
chr22_+_35796108 0.18 ENST00000382011.5
ENST00000416905.1
 MCM5
 minichromosome maintenance complex component 5
chr17_+_45726803 0.18 ENST00000535458.2
ENST00000583648.1
 KPNB1
 karyopherin (importin) beta 1
chr16_-_10674528 0.18 ENST00000359543.3
 EMP2
 epithelial membrane protein 2
chr3_-_51975942 0.18 ENST00000232888.6
 RRP9
 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr2_+_219433588 0.18 ENST00000295701.5
 RQCD1
 RCD1 required for cell differentiation1 homolog (S. pombe)
chr11_+_125495862 0.18 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
 CHEK1
 checkpoint kinase 1
chr16_+_58426296 0.18 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
 GINS3
 GINS complex subunit 3 (Psf3 homolog)
chr10_-_77161004 0.18 ENST00000418818.2
 RP11-399K21.11
 RP11-399K21.11
chr12_-_122238913 0.17 ENST00000537157.1
 AC084018.1
 AC084018.1
chr19_-_57352064 0.17 ENST00000326441.9
ENST00000593695.1
ENST00000599577.1
ENST00000594389.1
ENST00000423103.2
ENST00000598410.1
ENST00000593711.1
ENST00000391708.3
ENST00000221722.5
ENST00000599935.1
 PEG3
ZIM2
 paternally expressed 3
zinc finger, imprinted 2
chr2_+_48010221 0.17 ENST00000234420.5
 MSH6
 mutS homolog 6
chr3_-_10028366 0.17 ENST00000429759.1
 EMC3
 ER membrane protein complex subunit 3
chrX_-_122866874 0.17 ENST00000245838.8
ENST00000355725.4
 THOC2
 THO complex 2
chr5_-_137548997 0.16 ENST00000505120.1
ENST00000394886.2
ENST00000394884.3
 CDC23
 cell division cycle 23
chr19_+_10764937 0.16 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
 ILF3
 interleukin enhancer binding factor 3, 90kDa
chr5_-_140998481 0.16 ENST00000518047.1
 DIAPH1
 diaphanous-related formin 1
chr11_+_9406169 0.16 ENST00000379719.3
ENST00000527431.1
 IPO7
 importin 7
chr3_+_182511266 0.16 ENST00000323116.5
ENST00000493826.1
 ATP11B
 ATPase, class VI, type 11B
chr17_-_42580738 0.16 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
 GPATCH8
 G patch domain containing 8
chr2_+_48010312 0.15 ENST00000540021.1
 MSH6
 mutS homolog 6
chr1_+_13910194 0.15 ENST00000376057.4
ENST00000510906.1
 PDPN
 podoplanin
chr5_-_140998616 0.15 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
 DIAPH1
 diaphanous-related formin 1
chr16_+_29984962 0.15 ENST00000308893.4
 TAOK2
 TAO kinase 2
chr3_+_41240925 0.15 ENST00000396183.3
ENST00000349496.5
ENST00000453024.1
 CTNNB1
 catenin (cadherin-associated protein), beta 1, 88kDa
chr17_+_74734052 0.14 ENST00000590514.1
 MFSD11
 major facilitator superfamily domain containing 11
chr16_-_12009833 0.14 ENST00000420576.2
 GSPT1
 G1 to S phase transition 1
chr18_+_2655849 0.14 ENST00000261598.8
 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
chr17_+_45727204 0.14 ENST00000290158.4
 KPNB1
 karyopherin (importin) beta 1
chr22_+_35653445 0.14 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
 HMGXB4
 HMG box domain containing 4
chr7_+_26241310 0.14 ENST00000396386.2
 CBX3
 chromobox homolog 3
chr2_+_171571827 0.14 ENST00000375281.3
 SP5
 Sp5 transcription factor
chr5_-_176738883 0.14 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
 MXD3
 MAX dimerization protein 3
chr12_+_27932803 0.14 ENST00000381271.2
 KLHL42
 kelch-like family member 42
chr4_-_174256276 0.14 ENST00000296503.5
 HMGB2
 high mobility group box 2
chr19_+_50887585 0.14 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
 POLD1
 polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_95565673 0.13 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
 KIAA1429
 KIAA1429
chr12_-_45270151 0.13 ENST00000429094.2
 NELL2
 NEL-like 2 (chicken)
chr1_-_151119087 0.13 ENST00000341697.3
ENST00000368914.3
 SEMA6C
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr2_-_27632390 0.13 ENST00000350803.4
ENST00000344034.4
 PPM1G
 protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr10_-_131762105 0.13 ENST00000368648.3
ENST00000355311.5
 EBF3
 early B-cell factor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.6 2.9 GO:0060356 leucine import(GO:0060356)
0.5 1.6 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.5 1.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 1.2 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.3 4.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 0.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.3 1.1 GO:0006272 leading strand elongation(GO:0006272)
0.3 0.8 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 1.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 1.3 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.2 1.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 1.5 GO:0048478 replication fork protection(GO:0048478)
0.2 2.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.7 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.8 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:0030474 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.7 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.9 GO:0033504 floor plate development(GO:0033504)
0.1 1.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.3 GO:0061010 gall bladder development(GO:0061010)
0.1 1.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 1.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 3.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.8 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.7 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.2 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0042148 strand invasion(GO:0042148)
0.1 0.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 1.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:2000017 negative regulation of mitotic cell cycle, embryonic(GO:0045976) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.3 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.7 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0072185 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 4.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.4 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0045141 meiotic telomere clustering(GO:0045141)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0000811 GINS complex(GO:0000811)
0.4 1.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 1.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.3 1.6 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.3 1.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.7 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 0.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.2 1.9 GO:0042555 MCM complex(GO:0042555)
0.1 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 2.6 GO:0000800 lateral element(GO:0000800)
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 1.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.9 GO:0000796 condensin complex(GO:0000796)
0.1 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0045120 pronucleus(GO:0045120)
0.0 1.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663) PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.2 GO:0036033 mediator complex binding(GO:0036033)
0.3 1.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 1.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 0.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 2.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 1.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.7 GO:0032142 single guanine insertion binding(GO:0032142)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0000150 recombinase activity(GO:0000150)
0.1 0.7 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.6 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 5.6 GO:0001047 core promoter binding(GO:0001047)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 3.8 GO:0042393 histone binding(GO:0042393)
0.0 2.0 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 7.3 PID ATR PATHWAY ATR signaling pathway
0.1 2.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.3 PID ATM PATHWAY ATM pathway
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 3.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 0.8 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.1 0.7 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism