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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for E4F1

Z-value: 1.10

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Transcription factors associated with E4F1

Gene Symbol Gene ID Gene Info
E4F1
ENSG00000167967.11 E4F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E4F1hg19_v2_chr16_+_2273558_22736370.353.9e-01Click!

Activity profile of E4F1 motif

Sorted Z-values of E4F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E4F1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_58179582 1.21 ENST00000371015.1
ENST00000395639.4
 PHACTR3
 phosphatase and actin regulator 3
chr1_+_2004901 1.03 ENST00000400921.2
 PRKCZ
 protein kinase C, zeta
chr1_+_2005425 0.99 ENST00000461106.2
 PRKCZ
 protein kinase C, zeta
chr6_+_28048753 0.69 ENST00000377325.1
 ZNF165
 zinc finger protein 165
chr17_-_4643114 0.63 ENST00000293778.6
 CXCL16
 chemokine (C-X-C motif) ligand 16
chr11_+_111411384 0.47 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
 LAYN
 layilin
chr19_+_45504688 0.39 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
 RELB
 v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_-_95274536 0.36 ENST00000297596.2
ENST00000396194.2
 GEM
 GTP binding protein overexpressed in skeletal muscle
chr7_-_36406750 0.34 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
 KIAA0895
 KIAA0895
chr4_+_75310851 0.33 ENST00000395748.3
ENST00000264487.2
 AREG
 amphiregulin
chr17_-_7165662 0.33 ENST00000571881.2
ENST00000360325.7
 CLDN7
 claudin 7
chr17_+_35294075 0.33 ENST00000254457.5
 LHX1
 LIM homeobox 1
chr8_-_66754172 0.32 ENST00000401827.3
 PDE7A
 phosphodiesterase 7A
chr7_-_140624499 0.32 ENST00000288602.6
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chr7_+_30174426 0.31 ENST00000324453.8
 C7orf41
 maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_75311019 0.31 ENST00000502307.1
 AREG
 amphiregulin
chr18_+_23806437 0.28 ENST00000578121.1
 TAF4B
 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr6_+_139456226 0.25 ENST00000367658.2
 HECA
 headcase homolog (Drosophila)
chr1_+_26496362 0.21 ENST00000374266.5
ENST00000270812.5
 ZNF593
 zinc finger protein 593
chr14_-_23388338 0.21 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
 RBM23
 RNA binding motif protein 23
chr6_-_34664612 0.20 ENST00000374023.3
ENST00000374026.3
 C6orf106
 chromosome 6 open reading frame 106
chr10_-_50970322 0.20 ENST00000374103.4
 OGDHL
 oxoglutarate dehydrogenase-like
chr5_-_95297534 0.19 ENST00000513343.1
ENST00000431061.2
 ELL2
 elongation factor, RNA polymerase II, 2
chr10_-_50970382 0.19 ENST00000419399.1
ENST00000432695.1
 OGDHL
 oxoglutarate dehydrogenase-like
chr11_-_77185094 0.19 ENST00000278568.4
ENST00000356341.3
 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
chrX_+_153237740 0.19 ENST00000369982.4
 TMEM187
 transmembrane protein 187
chr17_+_41476327 0.18 ENST00000320033.4
 ARL4D
 ADP-ribosylation factor-like 4D
chr4_+_47487285 0.16 ENST00000273859.3
ENST00000504445.1
 ATP10D
 ATPase, class V, type 10D
chr6_+_30029008 0.16 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
 ZNRD1
 zinc ribbon domain containing 1
chr22_+_39101728 0.15 ENST00000216044.5
ENST00000484657.1
 GTPBP1
 GTP binding protein 1
chr2_-_64881018 0.15 ENST00000313349.3
 SERTAD2
 SERTA domain containing 2
chr9_+_131644388 0.14 ENST00000372600.4
 LRRC8A
 leucine rich repeat containing 8 family, member A
chr9_+_131644781 0.13 ENST00000259324.5
 LRRC8A
 leucine rich repeat containing 8 family, member A
chr2_-_220408430 0.13 ENST00000243776.6
 CHPF
 chondroitin polymerizing factor
chr2_-_75426826 0.13 ENST00000305249.5
 TACR1
 tachykinin receptor 1
chr9_-_131644202 0.13 ENST00000320665.6
ENST00000436267.2
 CCBL1
 cysteine conjugate-beta lyase, cytoplasmic
chr9_+_131644398 0.13 ENST00000372599.3
 LRRC8A
 leucine rich repeat containing 8 family, member A
chr17_+_18087553 0.13 ENST00000399138.4
 ALKBH5
 alkB, alkylation repair homolog 5 (E. coli)
chr22_+_18121356 0.12 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
 BCL2L13
 BCL2-like 13 (apoptosis facilitator)
chr9_-_131644306 0.12 ENST00000302586.3
 CCBL1
 cysteine conjugate-beta lyase, cytoplasmic
chr3_+_150126101 0.12 ENST00000361875.3
ENST00000361136.2
 TSC22D2
 TSC22 domain family, member 2
chr17_-_36831156 0.12 ENST00000325814.5
 C17orf96
 chromosome 17 open reading frame 96
chr16_+_68057153 0.12 ENST00000358896.6
ENST00000568099.2
 DUS2
 dihydrouridine synthase 2
chr16_+_68056844 0.11 ENST00000565263.1
 DUS2
 dihydrouridine synthase 2
chr6_-_32812420 0.11 ENST00000374881.2
 PSMB8
 proteasome (prosome, macropain) subunit, beta type, 8
chr16_+_68057179 0.10 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
 DUS2
 dihydrouridine synthase 2
chr7_-_129592471 0.10 ENST00000473814.2
ENST00000490974.1
 UBE2H
 ubiquitin-conjugating enzyme E2H
chr22_-_41252962 0.10 ENST00000216218.3
 ST13
 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr5_-_95297678 0.10 ENST00000237853.4
 ELL2
 elongation factor, RNA polymerase II, 2
chr1_+_70820451 0.10 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
 HHLA3
 HERV-H LTR-associating 3
chr22_+_18121562 0.10 ENST00000355028.3
 BCL2L13
 BCL2-like 13 (apoptosis facilitator)
chr17_+_4643300 0.09 ENST00000433935.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr9_-_99382065 0.09 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
 CDC14B
 cell division cycle 14B
chrX_-_153236819 0.09 ENST00000354233.3
 HCFC1
 host cell factor C1 (VP16-accessory protein)
chr1_-_8086343 0.09 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
 ERRFI1
 ERBB receptor feedback inhibitor 1
chr16_+_29911666 0.09 ENST00000563177.1
ENST00000483405.1
 ASPHD1
 aspartate beta-hydroxylase domain containing 1
chr1_-_47184745 0.09 ENST00000544071.1
 EFCAB14
 EF-hand calcium binding domain 14
chr17_+_4643337 0.09 ENST00000592813.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr3_+_184053703 0.08 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
 FAM131A
 family with sequence similarity 131, member A
chr14_+_94492674 0.08 ENST00000203664.5
ENST00000553723.1
 OTUB2
 OTU domain, ubiquitin aldehyde binding 2
chr7_-_100026280 0.08 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
 ZCWPW1
 zinc finger, CW type with PWWP domain 1
chrX_-_153237258 0.08 ENST00000310441.7
 HCFC1
 host cell factor C1 (VP16-accessory protein)
chr19_+_52693259 0.07 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
 PPP2R1A
 protein phosphatase 2, regulatory subunit A, alpha
chr10_+_119000604 0.07 ENST00000298472.5
 SLC18A2
 solute carrier family 18 (vesicular monoamine transporter), member 2
chr1_+_180199393 0.07 ENST00000263726.2
 LHX4
 LIM homeobox 4
chr20_-_44420507 0.07 ENST00000243938.4
 WFDC3
 WAP four-disulfide core domain 3
chr3_-_107941209 0.07 ENST00000492106.1
 IFT57
 intraflagellar transport 57 homolog (Chlamydomonas)
chr6_-_31774714 0.07 ENST00000375661.5
 LSM2
 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_+_66188475 0.07 ENST00000311034.2
 NPAS4
 neuronal PAS domain protein 4
chr11_-_6633799 0.07 ENST00000299424.4
 TAF10
 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr7_-_129592700 0.07 ENST00000472396.1
ENST00000355621.3
 UBE2H
 ubiquitin-conjugating enzyme E2H
chr4_-_54930790 0.06 ENST00000263921.3
 CHIC2
 cysteine-rich hydrophobic domain 2
chr12_-_93836028 0.06 ENST00000318066.2
 UBE2N
 ubiquitin-conjugating enzyme E2N
chr6_+_47445467 0.06 ENST00000359314.5
 CD2AP
 CD2-associated protein
chr2_+_75185619 0.06 ENST00000483063.1
 POLE4
 polymerase (DNA-directed), epsilon 4, accessory subunit
chr10_+_64893039 0.05 ENST00000277746.6
ENST00000435510.2
 NRBF2
 nuclear receptor binding factor 2
chr16_+_29911864 0.05 ENST00000308748.5
 ASPHD1
 aspartate beta-hydroxylase domain containing 1
chr16_-_3767551 0.05 ENST00000246957.5
 TRAP1
 TNF receptor-associated protein 1
chr21_-_40720974 0.05 ENST00000380748.1
 HMGN1
 high mobility group nucleosome binding domain 1
chr12_+_122150646 0.05 ENST00000449592.2
 TMEM120B
 transmembrane protein 120B
chr3_+_101292939 0.05 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
 PCNP
 PEST proteolytic signal containing nuclear protein
chr6_-_53213587 0.05 ENST00000542638.1
ENST00000370913.5
ENST00000541407.1
 ELOVL5
 ELOVL fatty acid elongase 5
chr1_-_32110467 0.05 ENST00000440872.2
ENST00000373703.4
 PEF1
 penta-EF-hand domain containing 1
chr16_-_3767506 0.04 ENST00000538171.1
 TRAP1
 TNF receptor-associated protein 1
chr20_-_44600810 0.04 ENST00000322927.2
ENST00000426788.1
 ZNF335
 zinc finger protein 335
chr1_+_85527987 0.04 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
 WDR63
 WD repeat domain 63
chr1_+_9599540 0.04 ENST00000302692.6
 SLC25A33
 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr9_+_125027127 0.04 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
 MRRF
 mitochondrial ribosome recycling factor
chr11_+_3819049 0.04 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
 PGAP2
 post-GPI attachment to proteins 2
chr17_+_7211656 0.04 ENST00000416016.2
 EIF5A
 eukaryotic translation initiation factor 5A
chr5_-_133706695 0.04 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
 CDKL3
 cyclin-dependent kinase-like 3
chr14_-_39901618 0.04 ENST00000554932.1
ENST00000298097.7
 FBXO33
 F-box protein 33
chr21_-_40720995 0.04 ENST00000380749.5
 HMGN1
 high mobility group nucleosome binding domain 1
chr2_-_62115659 0.04 ENST00000544185.1
 CCT4
 chaperonin containing TCP1, subunit 4 (delta)
chr14_-_50053081 0.04 ENST00000396020.3
ENST00000245458.6
 RPS29
 ribosomal protein S29
chr17_-_80231557 0.04 ENST00000392334.2
ENST00000314028.6
 CSNK1D
 casein kinase 1, delta
chr19_+_54704610 0.04 ENST00000302907.4
 RPS9
 ribosomal protein S9
chr4_-_111558135 0.04 ENST00000394598.2
ENST00000394595.3
 PITX2
 paired-like homeodomain 2
chr19_+_54704990 0.04 ENST00000391753.2
 RPS9
 ribosomal protein S9
chr1_+_110527308 0.03 ENST00000369799.5
 AHCYL1
 adenosylhomocysteinase-like 1
chr2_-_62115725 0.03 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
 CCT4
 chaperonin containing TCP1, subunit 4 (delta)
chr15_-_53082178 0.03 ENST00000305901.5
 ONECUT1
 one cut homeobox 1
chr9_-_99381660 0.03 ENST00000375240.3
ENST00000463569.1
 CDC14B
 cell division cycle 14B
chr12_-_93835665 0.03 ENST00000552442.1
ENST00000550657.1
 UBE2N
 ubiquitin-conjugating enzyme E2N
chr11_-_67276100 0.03 ENST00000301488.3
 CDK2AP2
 cyclin-dependent kinase 2 associated protein 2
chr19_+_1941117 0.03 ENST00000255641.8
 CSNK1G2
 casein kinase 1, gamma 2
chr16_-_27561209 0.03 ENST00000356183.4
ENST00000561623.1
 GTF3C1
 general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr17_+_7476136 0.03 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
 EIF4A1
 eukaryotic translation initiation factor 4A1
chr6_-_144416737 0.03 ENST00000367569.2
 SF3B5
 splicing factor 3b, subunit 5, 10kDa
chr6_+_32812568 0.03 ENST00000414474.1
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr17_-_80231300 0.03 ENST00000398519.5
ENST00000580446.1
 CSNK1D
 casein kinase 1, delta
chr14_+_105219437 0.02 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
 SIVA1
 SIVA1, apoptosis-inducing factor
chr17_+_53342311 0.02 ENST00000226067.5
 HLF
 hepatic leukemia factor
chr5_+_68513557 0.02 ENST00000256441.4
 MRPS36
 mitochondrial ribosomal protein S36
chr11_+_66059339 0.02 ENST00000327259.4
 TMEM151A
 transmembrane protein 151A
chr9_-_125027079 0.02 ENST00000417201.3
 RBM18
 RNA binding motif protein 18
chr17_+_42385927 0.02 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
 RUNDC3A
 RUN domain containing 3A
chr6_-_163148780 0.02 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
 PARK2
 parkin RBR E3 ubiquitin protein ligase
chr9_+_125026882 0.02 ENST00000297908.3
ENST00000373730.3
ENST00000546115.1
ENST00000344641.3
 MRRF
 mitochondrial ribosome recycling factor
chr1_-_16482554 0.02 ENST00000358432.5
 EPHA2
 EPH receptor A2
chr3_+_185303962 0.02 ENST00000296257.5
 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
chr4_+_1873100 0.02 ENST00000508803.1
 WHSC1
 Wolf-Hirschhorn syndrome candidate 1
chr7_-_86849883 0.01 ENST00000433078.1
 TMEM243
 transmembrane protein 243, mitochondrial
chr8_-_29208183 0.01 ENST00000240100.2
 DUSP4
 dual specificity phosphatase 4
chr3_-_107941230 0.01 ENST00000264538.3
 IFT57
 intraflagellar transport 57 homolog (Chlamydomonas)
chr6_+_44355257 0.00 ENST00000371477.3
 CDC5L
 cell division cycle 5-like
chr3_+_140660634 0.00 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
 SLC25A36
 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr17_+_39845134 0.00 ENST00000591776.1
ENST00000469257.1
 EIF1
 eukaryotic translation initiation factor 1
chr22_+_32340447 0.00 ENST00000248975.5
 YWHAH
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr10_-_119134918 0.00 ENST00000334464.5
 PDZD8
 PDZ domain containing 8
chr8_+_94929168 0.00 ENST00000518107.1
ENST00000396200.3
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.3 GO:0060067 cervix development(GO:0060067)
0.1 0.6 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.0 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.2 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism