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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for EGR1_EGR4

Z-value: 0.17

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Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
EGR1
ENSG00000120738.7 EGR1
EGR4
ENSG00000135625.6 EGR4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR1hg19_v2_chr5_+_137801160_1378011790.452.6e-01Click!
EGR4hg19_v2_chr2_-_73520667_735208330.196.5e-01Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_44365020 0.89 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
 CAMK2B
 calcium/calmodulin-dependent protein kinase II beta
chr2_+_191513959 0.35 ENST00000337386.5
ENST00000357215.5
 NAB1
 NGFI-A binding protein 1 (EGR1 binding protein 1)
chr11_+_124609742 0.35 ENST00000284292.6
 NRGN
 neurogranin (protein kinase C substrate, RC3)
chr11_+_124609823 0.35 ENST00000412681.2
 NRGN
 neurogranin (protein kinase C substrate, RC3)
chr16_+_1203194 0.34 ENST00000348261.5
ENST00000358590.4
 CACNA1H
 calcium channel, voltage-dependent, T type, alpha 1H subunit
chr9_-_124976185 0.33 ENST00000464484.2
 LHX6
 LIM homeobox 6
chr19_+_45844032 0.32 ENST00000589837.1
 KLC3
 kinesin light chain 3
chr10_+_49514698 0.32 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
 MAPK8
 mitogen-activated protein kinase 8
chr1_-_23694794 0.31 ENST00000374608.3
 ZNF436
 zinc finger protein 436
chr1_+_65886244 0.30 ENST00000344610.8
 LEPR
 leptin receptor
chr17_-_42402138 0.30 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
 SLC25A39
 solute carrier family 25, member 39
chr15_+_72410629 0.30 ENST00000340912.4
ENST00000544171.1
 SENP8
 SUMO/sentrin specific peptidase family member 8
chr7_-_44365216 0.29 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
 CAMK2B
 calcium/calmodulin-dependent protein kinase II beta
chr19_-_49371711 0.27 ENST00000355496.5
ENST00000263265.6
 PLEKHA4
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr19_-_14201776 0.27 ENST00000269724.5
 SAMD1
 sterile alpha motif domain containing 1
chr19_+_47778119 0.27 ENST00000552360.2
 PRR24
 proline rich 24
chr2_+_191513789 0.27 ENST00000409581.1
 NAB1
 NGFI-A binding protein 1 (EGR1 binding protein 1)
chr3_-_38691119 0.27 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
 SCN5A
 sodium channel, voltage-gated, type V, alpha subunit
chr1_+_23695680 0.26 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
 C1orf213
 chromosome 1 open reading frame 213
chr20_-_17539456 0.26 ENST00000544874.1
ENST00000377868.2
 BFSP1
 beaded filament structural protein 1, filensin
chr1_+_203274639 0.26 ENST00000290551.4
 BTG2
 BTG family, member 2
chr17_+_57408994 0.26 ENST00000312655.4
 YPEL2
 yippee-like 2 (Drosophila)
chr12_+_57482665 0.26 ENST00000300131.3
 NAB2
 NGFI-A binding protein 2 (EGR1 binding protein 2)
chr9_-_130742792 0.26 ENST00000373095.1
 FAM102A
 family with sequence similarity 102, member A
chr14_-_21566731 0.25 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr9_-_95896550 0.25 ENST00000375446.4
 NINJ1
 ninjurin 1
chr1_+_6845578 0.25 ENST00000467404.2
ENST00000439411.2
 CAMTA1
 calmodulin binding transcription activator 1
chr1_+_6845497 0.25 ENST00000473578.1
ENST00000557126.1
 CAMTA1
 calmodulin binding transcription activator 1
chr19_-_46405861 0.25 ENST00000322217.5
 MYPOP
 Myb-related transcription factor, partner of profilin
chr16_+_67062996 0.24 ENST00000561924.2
 CBFB
 core-binding factor, beta subunit
chr12_+_77158021 0.24 ENST00000550876.1
 ZDHHC17
 zinc finger, DHHC-type containing 17
chr12_+_57482877 0.23 ENST00000342556.6
ENST00000357680.4
 NAB2
 NGFI-A binding protein 2 (EGR1 binding protein 2)
chr1_+_43148059 0.23 ENST00000321358.7
ENST00000332220.6
 YBX1
 Y box binding protein 1
chr9_-_124976154 0.23 ENST00000482062.1
 LHX6
 LIM homeobox 6
chrX_-_154033793 0.23 ENST00000369534.3
ENST00000413259.3
 MPP1
 membrane protein, palmitoylated 1, 55kDa
chrX_-_48814278 0.22 ENST00000455452.1
 OTUD5
 OTU domain containing 5
chr18_-_658244 0.22 ENST00000585033.1
ENST00000323813.3
 C18orf56
 chromosome 18 open reading frame 56
chr12_+_70760056 0.22 ENST00000258111.4
 KCNMB4
 potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr20_+_61569463 0.22 ENST00000266069.3
 GID8
 GID complex subunit 8
chr7_+_100797726 0.21 ENST00000429457.1
 AP1S1
 adaptor-related protein complex 1, sigma 1 subunit
chr11_+_63998198 0.21 ENST00000321460.5
 DNAJC4
 DnaJ (Hsp40) homolog, subfamily C, member 4
chr2_+_30454390 0.21 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
 LBH
 limb bud and heart development
chr10_+_23728198 0.21 ENST00000376495.3
 OTUD1
 OTU domain containing 1
chr4_-_90758227 0.21 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr18_+_3449821 0.21 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
 TGIF1
 TGFB-induced factor homeobox 1
chr11_-_72492903 0.21 ENST00000537947.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr2_+_30370382 0.20 ENST00000402708.1
 YPEL5
 yippee-like 5 (Drosophila)
chr11_-_72492878 0.20 ENST00000535054.1
ENST00000545082.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr19_+_8455200 0.20 ENST00000601897.1
ENST00000594216.1
 RAB11B
 RAB11B, member RAS oncogene family
chr11_-_62313090 0.20 ENST00000528508.1
ENST00000533365.1
 AHNAK
 AHNAK nucleoprotein
chr4_-_78740511 0.20 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
chr11_+_134201911 0.19 ENST00000389881.3
 GLB1L2
 galactosidase, beta 1-like 2
chr1_-_209979375 0.19 ENST00000367021.3
 IRF6
 interferon regulatory factor 6
chr1_-_209979465 0.19 ENST00000542854.1
 IRF6
 interferon regulatory factor 6
chrX_-_154033661 0.19 ENST00000393531.1
 MPP1
 membrane protein, palmitoylated 1, 55kDa
chr19_+_3572758 0.19 ENST00000416526.1
 HMG20B
 high mobility group 20B
chr11_+_67071050 0.18 ENST00000376757.5
 SSH3
 slingshot protein phosphatase 3
chr4_-_90758118 0.18 ENST00000420646.2
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_67070919 0.18 ENST00000308127.4
ENST00000308298.7
 SSH3
 slingshot protein phosphatase 3
chr8_-_127570603 0.18 ENST00000304916.3
 FAM84B
 family with sequence similarity 84, member B
chr12_-_53625958 0.18 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
 RARG
 retinoic acid receptor, gamma
chr9_-_77643189 0.18 ENST00000376837.3
 C9orf41
 chromosome 9 open reading frame 41
chr1_+_65886326 0.18 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
 LEPR
 leptin receptor
chr20_-_22565101 0.18 ENST00000419308.2
 FOXA2
 forkhead box A2
chrX_-_3631635 0.17 ENST00000262848.5
 PRKX
 protein kinase, X-linked
chr17_+_37783170 0.17 ENST00000254079.4
 PPP1R1B
 protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_+_155051305 0.17 ENST00000368408.3
 EFNA3
 ephrin-A3
chr2_+_23608064 0.17 ENST00000486442.1
 KLHL29
 kelch-like family member 29
chr18_+_3448455 0.17 ENST00000549780.1
 TGIF1
 TGFB-induced factor homeobox 1
chr12_-_49351148 0.17 ENST00000398092.4
ENST00000539611.1
 RP11-302B13.5
ARF3
 ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr12_+_54378923 0.16 ENST00000303460.4
 HOXC10
 homeobox C10
chr19_-_14201507 0.16 ENST00000533683.2
 SAMD1
 sterile alpha motif domain containing 1
chr19_+_7985880 0.16 ENST00000597584.1
 SNAPC2
 small nuclear RNA activating complex, polypeptide 2, 45kDa
chr11_-_46142948 0.16 ENST00000257821.4
 PHF21A
 PHD finger protein 21A
chr12_-_49351228 0.16 ENST00000541959.1
ENST00000447318.2
 ARF3
 ADP-ribosylation factor 3
chr2_-_27718052 0.16 ENST00000264703.3
 FNDC4
 fibronectin type III domain containing 4
chr2_+_220306745 0.16 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
 SPEG
 SPEG complex locus
chr7_-_75368248 0.16 ENST00000434438.2
ENST00000336926.6
 HIP1
 huntingtin interacting protein 1
chr22_-_29137771 0.15 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
 CHEK2
 checkpoint kinase 2
chr16_+_30194916 0.15 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
 CORO1A
 coronin, actin binding protein, 1A
chr6_+_33172407 0.15 ENST00000374662.3
 HSD17B8
 hydroxysteroid (17-beta) dehydrogenase 8
chr5_-_176924562 0.15 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
 PDLIM7
 PDZ and LIM domain 7 (enigma)
chr16_+_2933229 0.15 ENST00000573965.1
ENST00000572006.1
 FLYWCH2
 FLYWCH family member 2
chr2_-_128145498 0.15 ENST00000409179.2
 MAP3K2
 mitogen-activated protein kinase kinase kinase 2
chr17_-_19281203 0.15 ENST00000487415.2
 B9D1
 B9 protein domain 1
chr3_+_39093481 0.15 ENST00000302313.5
ENST00000544962.1
ENST00000396258.3
ENST00000418020.1
 WDR48
 WD repeat domain 48
chr7_+_100860949 0.15 ENST00000305105.2
 ZNHIT1
 zinc finger, HIT-type containing 1
chr5_+_172483347 0.15 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
 CREBRF
 CREB3 regulatory factor
chr21_+_17102311 0.15 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
 USP25
 ubiquitin specific peptidase 25
chr19_+_45844018 0.15 ENST00000585434.1
 KLC3
 kinesin light chain 3
chr15_+_40733387 0.15 ENST00000416165.1
 BAHD1
 bromo adjacent homology domain containing 1
chr1_-_38471156 0.15 ENST00000373016.3
 FHL3
 four and a half LIM domains 3
chr14_+_100531615 0.15 ENST00000392920.3
 EVL
 Enah/Vasp-like
chr11_-_18034549 0.15 ENST00000528200.1
 SERGEF
 secretion regulating guanine nucleotide exchange factor
chr19_-_33793430 0.14 ENST00000498907.2
 CEBPA
 CCAAT/enhancer binding protein (C/EBP), alpha
chr19_+_45843994 0.14 ENST00000391946.2
 KLC3
 kinesin light chain 3
chr5_+_139028510 0.14 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
 CXXC5
 CXXC finger protein 5
chrX_-_48901012 0.14 ENST00000315869.7
 TFE3
 transcription factor binding to IGHM enhancer 3
chr10_-_127511790 0.14 ENST00000368797.4
ENST00000420761.1
 UROS
 uroporphyrinogen III synthase
chr12_-_58240470 0.14 ENST00000548823.1
ENST00000398073.2
 CTDSP2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_+_43148625 0.14 ENST00000436427.1
 YBX1
 Y box binding protein 1
chr1_+_211432700 0.14 ENST00000452621.2
 RCOR3
 REST corepressor 3
chr20_+_17207665 0.14 ENST00000536609.1
 PCSK2
 proprotein convertase subtilisin/kexin type 2
chr16_+_3014217 0.14 ENST00000572045.1
 KREMEN2
 kringle containing transmembrane protein 2
chr10_+_104178946 0.13 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr14_+_96342729 0.13 ENST00000504119.1
 LINC00617
 long intergenic non-protein coding RNA 617
chr3_-_88108192 0.13 ENST00000309534.6
 CGGBP1
 CGG triplet repeat binding protein 1
chr22_-_30722912 0.13 ENST00000215790.7
 TBC1D10A
 TBC1 domain family, member 10A
chr17_-_73178599 0.13 ENST00000578238.1
 SUMO2
 small ubiquitin-like modifier 2
chr6_-_53530474 0.13 ENST00000370905.3
 KLHL31
 kelch-like family member 31
chr16_-_67969888 0.13 ENST00000574576.2
 PSMB10
 proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_26348582 0.13 ENST00000535504.1
 SSPN
 sarcospan
chr19_-_55691377 0.13 ENST00000589172.1
 SYT5
 synaptotagmin V
chr11_+_63998006 0.13 ENST00000355040.4
 DNAJC4
 DnaJ (Hsp40) homolog, subfamily C, member 4
chr9_+_137218362 0.13 ENST00000481739.1
 RXRA
 retinoid X receptor, alpha
chr1_+_24104869 0.13 ENST00000246151.4
 PITHD1
 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr8_-_75233563 0.13 ENST00000342232.4
 JPH1
 junctophilin 1
chr4_-_82136114 0.13 ENST00000395578.1
ENST00000418486.2
 PRKG2
 protein kinase, cGMP-dependent, type II
chr11_-_18034701 0.13 ENST00000265965.5
 SERGEF
 secretion regulating guanine nucleotide exchange factor
chr19_+_10400615 0.13 ENST00000221980.4
 ICAM5
 intercellular adhesion molecule 5, telencephalin
chr11_-_46142615 0.13 ENST00000529734.1
ENST00000323180.6
 PHF21A
 PHD finger protein 21A
chr1_-_6321035 0.13 ENST00000377893.2
 GPR153
 G protein-coupled receptor 153
chr7_+_100797678 0.13 ENST00000337619.5
 AP1S1
 adaptor-related protein complex 1, sigma 1 subunit
chr17_+_17380294 0.13 ENST00000268711.3
ENST00000580462.1
 MED9
 mediator complex subunit 9
chr3_+_37903432 0.12 ENST00000443503.2
 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr5_+_179921430 0.12 ENST00000393356.1
 CNOT6
 CCR4-NOT transcription complex, subunit 6
chr9_-_130661916 0.12 ENST00000373142.1
ENST00000373146.1
ENST00000373144.3
 ST6GALNAC6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr17_-_61920280 0.12 ENST00000448276.2
ENST00000577990.1
 SMARCD2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr4_+_38869298 0.12 ENST00000510213.1
ENST00000515037.1
 FAM114A1
 family with sequence similarity 114, member A1
chr20_-_48099182 0.12 ENST00000371741.4
 KCNB1
 potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_+_38273988 0.12 ENST00000446260.2
 C1orf122
 chromosome 1 open reading frame 122
chr2_+_232651124 0.12 ENST00000350033.3
ENST00000412591.1
ENST00000410017.1
ENST00000373608.3
 COPS7B
 COP9 signalosome subunit 7B
chr2_+_46524537 0.12 ENST00000263734.3
 EPAS1
 endothelial PAS domain protein 1
chr10_+_131265443 0.12 ENST00000306010.7
 MGMT
 O-6-methylguanine-DNA methyltransferase
chr19_-_2050852 0.12 ENST00000541165.1
ENST00000591601.1
 MKNK2
 MAP kinase interacting serine/threonine kinase 2
chr6_-_19804973 0.12 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
 RP4-625H18.2
 RP4-625H18.2
chr22_-_30722866 0.12 ENST00000403477.3
 TBC1D10A
 TBC1 domain family, member 10A
chr21_+_38445539 0.12 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
 TTC3
 tetratricopeptide repeat domain 3
chr1_+_26146397 0.12 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
 MTFR1L
 mitochondrial fission regulator 1-like
chr9_-_140196703 0.12 ENST00000356628.2
 NRARP
 NOTCH-regulated ankyrin repeat protein
chr11_-_18034430 0.12 ENST00000530613.1
ENST00000532389.1
ENST00000529728.1
ENST00000532265.1
 SERGEF
 secretion regulating guanine nucleotide exchange factor
chr16_+_3014269 0.12 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
 KREMEN2
 kringle containing transmembrane protein 2
chr19_+_46144884 0.11 ENST00000593161.1
 AC006132.1
 chromosome 19 open reading frame 83
chr19_-_35992780 0.11 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
 DMKN
 dermokine
chrX_-_107334750 0.11 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
 PSMD10
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_+_43803790 0.11 ENST00000424330.1
 BLVRA
 biliverdin reductase A
chrX_-_107334790 0.11 ENST00000217958.3
 PSMD10
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr12_-_124457257 0.11 ENST00000545891.1
 CCDC92
 coiled-coil domain containing 92
chr1_+_38273818 0.11 ENST00000373042.4
 C1orf122
 chromosome 1 open reading frame 122
chr16_+_67063262 0.11 ENST00000565389.1
 CBFB
 core-binding factor, beta subunit
chr21_+_27543175 0.11 ENST00000608591.1
ENST00000609365.1
 AP000230.1
 AP000230.1
chr12_+_51632638 0.11 ENST00000549732.2
 DAZAP2
 DAZ associated protein 2
chr9_+_90112117 0.11 ENST00000358077.5
 DAPK1
 death-associated protein kinase 1
chr3_-_180707466 0.11 ENST00000491873.1
ENST00000486355.1
ENST00000382564.2
 DNAJC19
 DnaJ (Hsp40) homolog, subfamily C, member 19
chr9_+_34989638 0.11 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
 DNAJB5
 DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_+_85646891 0.11 ENST00000393243.1
 GSE1
 Gse1 coiled-coil protein
chr19_-_13068012 0.11 ENST00000316939.1
 GADD45GIP1
 growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr2_-_25896380 0.11 ENST00000545439.1
ENST00000407186.1
ENST00000406818.3
ENST00000404103.3
ENST00000407661.3
ENST00000407038.3
ENST00000405222.1
ENST00000288642.8
 DTNB
 dystrobrevin, beta
chr17_+_4613776 0.11 ENST00000269260.2
 ARRB2
 arrestin, beta 2
chr14_-_23822080 0.11 ENST00000397267.1
ENST00000354772.3
 SLC22A17
 solute carrier family 22, member 17
chr6_+_35995552 0.11 ENST00000468133.1
 MAPK14
 mitogen-activated protein kinase 14
chr3_-_185542817 0.11 ENST00000382199.2
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr9_+_841690 0.11 ENST00000382276.3
 DMRT1
 doublesex and mab-3 related transcription factor 1
chr11_-_75062730 0.11 ENST00000420843.2
ENST00000360025.3
 ARRB1
 arrestin, beta 1
chr8_-_102217796 0.11 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
 ZNF706
 zinc finger protein 706
chr6_-_4135825 0.11 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
 ECI2
 enoyl-CoA delta isomerase 2
chr14_-_89883412 0.11 ENST00000557258.1
 FOXN3
 forkhead box N3
chr17_-_6947225 0.11 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
 SLC16A11
 solute carrier family 16, member 11
chr1_+_26147319 0.11 ENST00000374300.3
 MTFR1L
 mitochondrial fission regulator 1-like
chr9_+_127020202 0.10 ENST00000373600.3
ENST00000320246.5
 NEK6
 NIMA-related kinase 6
chr11_-_65640198 0.10 ENST00000528176.1
 EFEMP2
 EGF containing fibulin-like extracellular matrix protein 2
chrX_-_51239425 0.10 ENST00000375992.3
 NUDT11
 nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr5_-_176923803 0.10 ENST00000506161.1
 PDLIM7
 PDZ and LIM domain 7 (enigma)
chr17_-_8027402 0.10 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
 HES7
 hes family bHLH transcription factor 7
chr7_+_150782945 0.10 ENST00000463381.1
 AGAP3
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr18_+_22006580 0.10 ENST00000284202.4
 IMPACT
 impact RWD domain protein
chr7_+_127228399 0.10 ENST00000000233.5
ENST00000415666.1
 ARF5
 ADP-ribosylation factor 5
chr17_+_11924129 0.10 ENST00000353533.5
ENST00000415385.3
 MAP2K4
 mitogen-activated protein kinase kinase 4
chr16_+_1359138 0.10 ENST00000325437.5
 UBE2I
 ubiquitin-conjugating enzyme E2I
chr5_+_172068232 0.10 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
 NEURL1B
 neuralized E3 ubiquitin protein ligase 1B
chr1_-_146644036 0.10 ENST00000425272.2
 PRKAB2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr1_+_235490659 0.10 ENST00000488594.1
 GGPS1
 geranylgeranyl diphosphate synthase 1
chrX_+_134555863 0.10 ENST00000417443.2
 LINC00086
 long intergenic non-protein coding RNA 86
chr8_-_30515693 0.10 ENST00000355904.4
 GTF2E2
 general transcription factor IIE, polypeptide 2, beta 34kDa
chr10_-_99393208 0.10 ENST00000307450.6
 MORN4
 MORN repeat containing 4
chrX_+_153237740 0.10 ENST00000369982.4
 TMEM187
 transmembrane protein 187
chr19_+_39897453 0.10 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
 ZFP36
 ZFP36 ring finger protein
chr9_+_35829208 0.10 ENST00000439587.2
ENST00000377991.4
 TMEM8B
 transmembrane protein 8B
chr12_+_50017184 0.10 ENST00000548825.2
 PRPF40B
 PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr7_+_128502871 0.10 ENST00000249289.4
 ATP6V1F
 ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr15_+_57884086 0.10 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
 GCOM1
 GRINL1A complex locus 1
chr9_-_86432547 0.10 ENST00000376365.3
ENST00000376371.2
 GKAP1
 G kinase anchoring protein 1
chr10_-_134145321 0.10 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
 STK32C
 serine/threonine kinase 32C
chr14_-_99947121 0.10 ENST00000329331.3
ENST00000436070.2
 SETD3
 SET domain containing 3
chr1_+_212458834 0.10 ENST00000261461.2
 PPP2R5A
 protein phosphatase 2, regulatory subunit B', alpha
chr9_+_127020503 0.10 ENST00000545174.1
ENST00000444973.1
ENST00000454453.1
 NEK6
 NIMA-related kinase 6
chr2_+_27651519 0.10 ENST00000379863.3
 NRBP1
 nuclear receptor binding protein 1
chr10_-_105452917 0.10 ENST00000427662.2
 SH3PXD2A
 SH3 and PX domains 2A
chr14_-_51561784 0.10 ENST00000360392.4
 TRIM9
 tripartite motif containing 9
chr6_+_72596604 0.10 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
 RIMS1
 regulating synaptic membrane exocytosis 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.4 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 1.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.1 GO:1901656 glycoside transport(GO:1901656)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.1 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.5 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.1 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0048864 stem cell development(GO:0048864)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0060129 mesendoderm development(GO:0048382) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0072301 regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.4 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.6 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.0 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0090189 regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.0 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.0 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0097327 response to antineoplastic agent(GO:0097327)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0052844 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0052831 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.0 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex