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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for EN1_ESX1_GBX1

Z-value: 0.45

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
ENSG00000163064.6 EN1
ENSG00000123576.5 ESX1
ENSG00000164900.4 GBX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GBX1hg19_v2_chr7_-_150864635_150864785-0.206.3e-01Click!
ESX1hg19_v2_chrX_-_103499602_1034996170.157.1e-01Click!
EN1hg19_v2_chr2_-_119605253_119605264-0.019.7e-01Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_51522955 1.13 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr1_-_242612779 0.81 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr12_-_28123206 0.71 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr12_-_28122980 0.67 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr5_+_52776449 0.54 ENST00000396947.3
FST
follistatin
chr5_+_52776228 0.51 ENST00000256759.3
FST
follistatin
chr1_+_62439037 0.49 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr12_+_107712173 0.47 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr5_+_66300446 0.44 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_74486217 0.38 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr3_-_151034734 0.37 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr3_+_111718036 0.36 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_111717600 0.35 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718173 0.34 ENST00000494932.1
TAGLN3
transgelin 3
chr4_+_77356248 0.31 ENST00000296043.6
SHROOM3
shroom family member 3
chr3_+_111717511 0.30 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr12_-_52828147 0.30 ENST00000252245.5
KRT75
keratin 75
chr19_-_36001113 0.30 ENST00000434389.1
DMKN
dermokine
chr1_+_153746683 0.29 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr1_+_160160346 0.28 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_-_64225508 0.28 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_160160283 0.27 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr18_+_29027696 0.27 ENST00000257189.4
DSG3
desmoglein 3
chr8_-_41166953 0.26 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr4_-_74486347 0.25 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_74486109 0.24 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr5_-_82969405 0.24 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr4_+_40198527 0.23 ENST00000381799.5
RHOH
ras homolog family member H
chr3_+_130569429 0.22 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr5_+_135394840 0.22 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr6_+_130339710 0.22 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr17_-_19015945 0.21 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr1_+_153747746 0.21 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr14_+_22739823 0.20 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr10_-_50970322 0.20 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr8_+_98900132 0.20 ENST00000520016.1
MATN2
matrilin 2
chr1_+_160370344 0.19 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr4_-_143226979 0.19 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_-_7167279 0.19 ENST00000571932.2
CLDN7
claudin 7
chr10_-_50970382 0.19 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr8_+_32579341 0.19 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr8_+_98881268 0.19 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr8_-_86290333 0.19 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr14_-_78083112 0.19 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr13_-_86373536 0.18 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr14_-_38064198 0.18 ENST00000250448.2
FOXA1
forkhead box A1
chr20_-_50418947 0.18 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr18_+_55888767 0.18 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr4_-_143227088 0.18 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr20_-_50418972 0.18 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr1_+_28261533 0.18 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr16_+_50300427 0.18 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7
adenylate cyclase 7
chr3_-_160823040 0.17 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chrX_+_135730297 0.17 ENST00000370629.2
CD40LG
CD40 ligand
chr3_-_160823158 0.17 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr18_+_34124507 0.17 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr1_+_28261492 0.17 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_28261621 0.16 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr17_+_19091325 0.16 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr18_-_33709268 0.16 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr11_-_117748138 0.16 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747434 0.16 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747607 0.15 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chrX_+_134654540 0.15 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr5_-_141249154 0.15 ENST00000357517.5
ENST00000536585.1
PCDH1
protocadherin 1
chr12_+_20963647 0.15 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_+_41831485 0.15 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr12_-_89746173 0.15 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr12_+_20963632 0.14 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr4_-_46126093 0.14 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr10_-_118928543 0.14 ENST00000419373.2
RP11-501J20.2
RP11-501J20.2
chr17_-_39341594 0.14 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr9_-_5304432 0.14 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr19_-_7968427 0.14 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr2_+_68961934 0.14 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr11_-_124190184 0.14 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr2_+_68961905 0.14 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr12_+_122688090 0.14 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr6_-_111927062 0.14 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr17_-_18430160 0.13 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chrX_+_107288197 0.13 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr8_-_139926236 0.13 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr12_+_56473939 0.13 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr3_+_121774202 0.12 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr11_-_118023490 0.12 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr20_-_50419055 0.12 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr4_-_116034979 0.12 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr2_-_208031943 0.12 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr20_+_31805131 0.12 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr10_+_94451574 0.12 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chrX_+_107288239 0.11 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr12_+_44229846 0.11 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr3_+_97868170 0.11 ENST00000437310.1
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr19_+_34287751 0.11 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr1_-_109935819 0.11 ENST00000538502.1
SORT1
sortilin 1
chr2_+_159825143 0.11 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr4_-_8873531 0.11 ENST00000400677.3
HMX1
H6 family homeobox 1
chr5_-_24645078 0.11 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr17_-_39324424 0.11 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr11_-_128894053 0.10 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr21_-_32253874 0.10 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chrX_-_130423200 0.10 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr1_-_201140673 0.10 ENST00000367333.2
TMEM9
transmembrane protein 9
chr14_-_54423529 0.10 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr7_-_130080977 0.10 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr8_-_40755333 0.10 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr6_+_29274403 0.10 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr12_+_106751436 0.10 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr11_+_57435219 0.10 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr7_-_100860851 0.10 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr12_-_14849470 0.10 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr1_-_209979375 0.09 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr8_+_38831683 0.09 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr17_+_42785976 0.09 ENST00000393547.2
ENST00000398338.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr19_-_6737576 0.09 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chrX_-_110655306 0.09 ENST00000371993.2
DCX
doublecortin
chr4_-_105416039 0.09 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr7_+_73245193 0.09 ENST00000340958.2
CLDN4
claudin 4
chr3_-_74570291 0.09 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr14_+_22670455 0.09 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr8_-_20040638 0.09 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr17_-_38911580 0.09 ENST00000312150.4
KRT25
keratin 25
chr18_+_5748793 0.09 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
RP11-945C19.1
chr21_-_42219065 0.09 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr13_-_36050819 0.09 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr1_+_209878182 0.09 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr8_-_20040601 0.09 ENST00000265808.7
ENST00000522513.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr4_+_71200681 0.09 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chrX_-_33229636 0.08 ENST00000357033.4
DMD
dystrophin
chr3_-_98235962 0.08 ENST00000513873.1
CLDND1
claudin domain containing 1
chr3_-_55521323 0.08 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr5_+_126984710 0.08 ENST00000379445.3
CTXN3
cortexin 3
chr17_-_27418537 0.08 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_+_117544366 0.08 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr16_+_9185450 0.08 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr9_-_107690420 0.08 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr17_+_47448102 0.08 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr11_-_129062093 0.08 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr7_+_116660246 0.08 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr11_+_34664014 0.08 ENST00000527935.1
EHF
ets homologous factor
chr4_+_70796784 0.08 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr17_+_42786051 0.08 ENST00000315005.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr19_+_39421556 0.08 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr4_-_72649763 0.08 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr1_+_118472343 0.08 ENST00000369441.3
ENST00000349139.5
WDR3
WD repeat domain 3
chr7_-_33102338 0.08 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr6_-_111927449 0.08 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr19_+_13049413 0.07 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr12_-_51422017 0.07 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr16_-_29910853 0.07 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr10_+_24497704 0.07 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr1_-_235098935 0.07 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr10_+_24755416 0.07 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr7_-_33102399 0.07 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr14_-_82000140 0.07 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr3_-_108248169 0.07 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr3_-_123339343 0.07 ENST00000578202.1
MYLK
myosin light chain kinase
chrX_+_135730373 0.07 ENST00000370628.2
CD40LG
CD40 ligand
chr4_+_78432907 0.07 ENST00000286758.4
CXCL13
chemokine (C-X-C motif) ligand 13
chr14_+_39734482 0.07 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5
CTAGE family, member 5
chr11_+_34663913 0.07 ENST00000532302.1
EHF
ets homologous factor
chrX_+_49687267 0.07 ENST00000376091.3
CLCN5
chloride channel, voltage-sensitive 5
chr19_+_4007644 0.07 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr1_+_244515930 0.07 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr1_+_171227069 0.07 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr3_-_143567262 0.07 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr4_-_25865159 0.07 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr22_-_32860427 0.06 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr20_+_43538756 0.06 ENST00000537323.1
ENST00000217073.2
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr15_+_58702742 0.06 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr5_+_140557371 0.06 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr5_-_74162605 0.06 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr2_-_99871570 0.06 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr4_+_169013666 0.06 ENST00000359299.3
ANXA10
annexin A10
chr19_-_6737241 0.06 ENST00000430424.4
ENST00000597298.1
GPR108
G protein-coupled receptor 108
chr15_+_54901540 0.06 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr14_+_68086515 0.06 ENST00000261783.3
ARG2
arginase 2
chr19_+_14640372 0.06 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
TECR
trans-2,3-enoyl-CoA reductase
chr6_+_135502501 0.06 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr1_+_81771806 0.06 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr20_+_43538692 0.06 ENST00000217074.4
ENST00000255136.3
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr6_+_127898312 0.06 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr9_+_136501478 0.06 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr2_-_101925055 0.06 ENST00000295317.3
RNF149
ring finger protein 149
chr1_+_236958554 0.06 ENST00000366577.5
ENST00000418145.2
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr12_+_16500599 0.06 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr6_-_31088214 0.06 ENST00000376288.2
CDSN
corneodesmosin
chr6_+_30881982 0.06 ENST00000321897.5
ENST00000416670.2
ENST00000542001.1
ENST00000428017.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr11_-_64684672 0.06 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr17_-_39296739 0.06 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr5_+_31193847 0.06 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr12_-_23737534 0.06 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chrM_+_12331 0.06 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr3_+_120626919 0.06 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L
syntaxin binding protein 5-like
chr11_+_65554493 0.06 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr9_-_5339873 0.06 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr19_+_45458503 0.06 ENST00000337392.5
ENST00000591304.1
CLPTM1
cleft lip and palate associated transmembrane protein 1
chr12_+_16500571 0.06 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr10_+_24738355 0.06 ENST00000307544.6
KIAA1217
KIAA1217
chr14_+_22771851 0.06 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.3 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.0 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0031437 regulation of mRNA cleavage(GO:0031437) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.0 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.4 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.0 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.0 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)