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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for EPAS1_BCL3

Z-value: 2.21

Motif logo

Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
ENSG00000116016.9 EPAS1
ENSG00000069399.8 BCL3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg19_v2_chr2_+_46524537_465245530.831.0e-02Click!
BCL3hg19_v2_chr19_+_45251804_452518400.611.1e-01Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_57662419 4.91 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr5_+_52776228 4.78 ENST00000256759.3
FST
follistatin
chr5_+_52776449 3.48 ENST00000396947.3
FST
follistatin
chr20_+_44637526 3.23 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr18_+_61254534 3.07 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_-_116163830 2.79 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr16_+_22825475 2.73 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr6_-_40555176 2.73 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr18_+_61254570 2.54 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr2_+_102618428 2.50 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr4_+_40198527 2.48 ENST00000381799.5
RHOH
ras homolog family member H
chr12_-_86230315 2.46 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr15_+_40531621 2.42 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_-_238499303 2.33 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr15_+_40532058 2.32 ENST00000260404.4
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr8_-_134309335 2.19 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr6_+_130686856 2.16 ENST00000296978.3
TMEM200A
transmembrane protein 200A
chr16_-_31147020 2.02 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr10_+_111967345 1.96 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr1_+_152486950 1.95 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr11_+_10472223 1.94 ENST00000396554.3
ENST00000524866.1
AMPD3
adenosine monophosphate deaminase 3
chr1_-_153588765 1.84 ENST00000368701.1
ENST00000344616.2
S100A14
S100 calcium binding protein A14
chr2_-_238499337 1.83 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr17_+_73750699 1.83 ENST00000584939.1
ITGB4
integrin, beta 4
chr6_-_136847610 1.81 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr1_+_209602156 1.80 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr19_-_43382142 1.79 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr6_-_136847099 1.76 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr16_+_71660079 1.73 ENST00000565261.1
ENST00000268485.3
ENST00000299952.4
MARVELD3
MARVEL domain containing 3
chr14_+_71108460 1.70 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr8_+_27348626 1.61 ENST00000517536.1
EPHX2
epoxide hydrolase 2, cytoplasmic
chr2_+_85360499 1.53 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr16_-_68269971 1.50 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr1_+_153003671 1.49 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr1_+_92495528 1.48 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr2_-_238499131 1.45 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr20_+_9049682 1.43 ENST00000334005.3
ENST00000378473.3
PLCB4
phospholipase C, beta 4
chr12_+_4385230 1.42 ENST00000536537.1
CCND2
cyclin D2
chr5_+_167181917 1.41 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr12_+_10163231 1.41 ENST00000396502.1
ENST00000338896.5
CLEC12B
C-type lectin domain family 12, member B
chr19_-_51456198 1.33 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr18_+_61445007 1.31 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr5_+_52285144 1.28 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr3_-_56809685 1.28 ENST00000413728.2
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr18_+_21452964 1.27 ENST00000587184.1
LAMA3
laminin, alpha 3
chr16_+_82068830 1.27 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr18_+_21452804 1.27 ENST00000269217.6
LAMA3
laminin, alpha 3
chr14_-_54420133 1.27 ENST00000559501.1
ENST00000558984.1
BMP4
bone morphogenetic protein 4
chr18_-_53089723 1.26 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr15_+_41136216 1.23 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr7_-_41742697 1.21 ENST00000242208.4
INHBA
inhibin, beta A
chr19_+_34287751 1.19 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr20_-_36793774 1.18 ENST00000361475.2
TGM2
transglutaminase 2
chr11_-_108464465 1.17 ENST00000525344.1
EXPH5
exophilin 5
chr11_-_79151695 1.16 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr15_+_43886057 1.13 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_41136586 1.11 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_-_125366089 1.10 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr3_-_12800751 1.09 ENST00000435218.2
ENST00000435575.1
TMEM40
transmembrane protein 40
chr15_+_43985725 1.05 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr20_+_51588873 1.05 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr1_+_46640750 1.04 ENST00000372003.1
TSPAN1
tetraspanin 1
chr17_-_41623009 1.04 ENST00000393664.2
ETV4
ets variant 4
chr3_-_69435428 1.04 ENST00000542259.1
FRMD4B
FERM domain containing 4B
chr1_+_186798073 1.03 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr15_+_48009541 1.03 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr11_+_10471836 1.02 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr3_-_69435224 1.01 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr19_-_36004543 1.01 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr16_+_71660052 1.01 ENST00000567566.1
MARVELD3
MARVEL domain containing 3
chr2_-_31360887 1.01 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_12012536 0.99 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr3_+_14444063 0.99 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr19_-_43099070 0.97 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr19_-_52227221 0.97 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr7_+_121513143 0.96 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr11_+_69924639 0.95 ENST00000538023.1
ENST00000398543.2
ANO1
anoctamin 1, calcium activated chloride channel
chr3_-_193272588 0.94 ENST00000295548.3
ATP13A4
ATPase type 13A4
chr17_-_41623075 0.93 ENST00000545089.1
ETV4
ets variant 4
chr19_+_7660716 0.93 ENST00000160298.4
ENST00000446248.2
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3
chr11_-_72433346 0.93 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr20_-_36793663 0.92 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr8_+_21915368 0.92 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr1_-_28520384 0.91 ENST00000305392.3
PTAFR
platelet-activating factor receptor
chr19_+_45843994 0.91 ENST00000391946.2
KLC3
kinesin light chain 3
chrX_+_17393543 0.88 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_-_11807277 0.88 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr8_+_27348649 0.87 ENST00000521780.1
ENST00000380476.3
ENST00000518379.1
ENST00000521684.1
EPHX2
epoxide hydrolase 2, cytoplasmic
chr19_+_45844018 0.84 ENST00000585434.1
KLC3
kinesin light chain 3
chr3_-_9291063 0.84 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr7_+_86273952 0.83 ENST00000536043.1
GRM3
glutamate receptor, metabotropic 3
chr1_+_3388181 0.82 ENST00000418137.1
ENST00000413250.2
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr7_+_86274145 0.81 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3
glutamate receptor, metabotropic 3
chrX_-_119445263 0.80 ENST00000309720.5
TMEM255A
transmembrane protein 255A
chr8_+_101170257 0.79 ENST00000251809.3
SPAG1
sperm associated antigen 1
chr12_-_28124903 0.79 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr1_+_233749739 0.79 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr13_+_37006421 0.79 ENST00000255465.4
CCNA1
cyclin A1
chr6_+_43737939 0.79 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr8_+_110374683 0.79 ENST00000378402.5
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr11_+_102188224 0.77 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr1_+_13910479 0.77 ENST00000509009.1
PDPN
podoplanin
chr6_-_134373732 0.76 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr17_-_41623691 0.76 ENST00000545954.1
ETV4
ets variant 4
chr4_+_140586922 0.76 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr8_-_81083890 0.75 ENST00000518937.1
TPD52
tumor protein D52
chrX_-_119445306 0.75 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr12_-_85306562 0.75 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr8_+_123793633 0.74 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr3_-_189838670 0.74 ENST00000319332.5
LEPREL1
leprecan-like 1
chr3_-_13921594 0.74 ENST00000285018.4
WNT7A
wingless-type MMTV integration site family, member 7A
chr1_+_174769006 0.73 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr13_+_37006398 0.73 ENST00000418263.1
CCNA1
cyclin A1
chr1_+_82266053 0.72 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr15_+_33603147 0.72 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chrX_+_105937068 0.71 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr14_+_61995722 0.71 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr12_-_8815404 0.71 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr11_+_76494253 0.71 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr17_-_41623259 0.71 ENST00000538265.1
ENST00000591713.1
ETV4
ets variant 4
chr19_-_55658650 0.70 ENST00000589226.1
TNNT1
troponin T type 1 (skeletal, slow)
chr10_+_5566916 0.70 ENST00000315238.1
CALML3
calmodulin-like 3
chr9_-_14722715 0.69 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr1_-_44497024 0.69 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_+_15479054 0.68 ENST00000376014.3
ENST00000451326.2
TMEM51
transmembrane protein 51
chr12_+_50451462 0.68 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr1_-_221915418 0.67 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr7_-_44365020 0.67 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr1_+_117452669 0.67 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr22_-_37545972 0.66 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr17_-_41623716 0.66 ENST00000319349.5
ETV4
ets variant 4
chr1_+_15479021 0.66 ENST00000428417.1
TMEM51
transmembrane protein 51
chr4_-_89152474 0.64 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr20_-_43743790 0.63 ENST00000307971.4
ENST00000372789.4
WFDC5
WAP four-disulfide core domain 5
chr16_+_57673430 0.62 ENST00000540164.2
ENST00000568531.1
GPR56
G protein-coupled receptor 56
chr11_-_72492878 0.62 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr3_-_46735155 0.62 ENST00000318962.4
ALS2CL
ALS2 C-terminal like
chr7_-_142120321 0.61 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr14_+_68086515 0.61 ENST00000261783.3
ARG2
arginase 2
chr19_+_45844032 0.60 ENST00000589837.1
KLC3
kinesin light chain 3
chr19_-_55660561 0.60 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr12_+_50451331 0.60 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr13_+_37005967 0.59 ENST00000440264.1
ENST00000449823.1
CCNA1
cyclin A1
chr17_+_7942424 0.59 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr19_-_11688447 0.59 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr16_-_70719925 0.58 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr9_-_14910990 0.58 ENST00000380881.4
ENST00000422223.2
FREM1
FRAS1 related extracellular matrix 1
chr1_+_13910757 0.57 ENST00000376061.4
ENST00000513143.1
PDPN
podoplanin
chr1_+_160765919 0.57 ENST00000341032.4
ENST00000368041.2
ENST00000368040.1
LY9
lymphocyte antigen 9
chr1_+_160765884 0.57 ENST00000392203.4
LY9
lymphocyte antigen 9
chr1_+_26869597 0.57 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_122459757 0.57 ENST00000261822.4
BCL7A
B-cell CLL/lymphoma 7A
chr1_-_44497118 0.56 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr8_+_21916680 0.56 ENST00000358242.3
ENST00000415253.1
DMTN
dematin actin binding protein
chr12_+_56473628 0.55 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_-_184006611 0.55 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chrX_-_32173579 0.55 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr1_+_15480197 0.55 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51
transmembrane protein 51
chr1_+_202172848 0.55 ENST00000255432.7
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr21_+_46117087 0.55 ENST00000400365.3
KRTAP10-12
keratin associated protein 10-12
chr8_+_21916710 0.55 ENST00000523266.1
ENST00000519907.1
DMTN
dematin actin binding protein
chr11_-_75062730 0.54 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr1_+_13910194 0.53 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr1_-_28520447 0.52 ENST00000539896.1
PTAFR
platelet-activating factor receptor
chr11_+_60869867 0.51 ENST00000347785.3
CD5
CD5 molecule
chr16_-_23521710 0.51 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr12_+_56473939 0.51 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_24646002 0.51 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr11_-_75062829 0.50 ENST00000393505.4
ARRB1
arrestin, beta 1
chr1_+_24645807 0.50 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr22_-_39637135 0.50 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr1_+_24645865 0.49 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_160765860 0.49 ENST00000368037.5
LY9
lymphocyte antigen 9
chr17_+_73717516 0.49 ENST00000200181.3
ENST00000339591.3
ITGB4
integrin, beta 4
chr3_-_171177852 0.49 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr10_+_23983671 0.49 ENST00000376462.1
KIAA1217
KIAA1217
chr19_-_38743878 0.48 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr2_+_74881398 0.48 ENST00000339773.5
ENST00000434486.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr1_+_33219592 0.48 ENST00000373481.3
KIAA1522
KIAA1522
chr19_-_52035044 0.47 ENST00000359982.4
ENST00000436458.1
ENST00000425629.3
ENST00000391797.3
ENST00000343300.4
SIGLEC6
sialic acid binding Ig-like lectin 6
chr3_-_168865522 0.47 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr12_-_57505121 0.47 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr5_-_33984786 0.47 ENST00000296589.4
SLC45A2
solute carrier family 45, member 2
chr2_+_203499901 0.47 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr10_+_24497704 0.47 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chrX_-_133792480 0.46 ENST00000359237.4
PLAC1
placenta-specific 1
chr4_-_143767428 0.46 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_146859623 0.45 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr4_+_103423055 0.45 ENST00000505458.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_-_138820624 0.45 ENST00000343505.5
NHSL1
NHS-like 1
chr10_-_103880209 0.45 ENST00000425280.1
LDB1
LIM domain binding 1
chr10_-_14590644 0.45 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr4_-_105416039 0.45 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr14_+_105147464 0.45 ENST00000540171.2
RP11-982M15.6
RP11-982M15.6
chr2_-_74780176 0.45 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr14_+_22694606 0.45 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr4_-_186732048 0.44 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr2_+_11273179 0.44 ENST00000381585.3
ENST00000405022.3
C2orf50
chromosome 2 open reading frame 50
chr12_-_24103954 0.44 ENST00000441133.2
ENST00000545921.1
SOX5
SRY (sex determining region Y)-box 5
chr16_+_3014269 0.44 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.9 9.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.7 2.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.6 2.5 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.6 1.9 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.6 2.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.5 1.5 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 3.0 GO:0006196 AMP catabolic process(GO:0006196)
0.5 1.4 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.4 5.4 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.4 1.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.4 1.3 GO:0003277 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4 2.0 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.4 1.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 1.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 3.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.3 1.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 0.8 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 1.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 0.8 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 0.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 1.3 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.9 GO:1905174 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 2.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 2.7 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 1.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 1.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 4.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.0 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 2.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.5 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.6 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 1.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 1.6 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.6 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 1.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.5 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.7 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 1.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 1.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 2.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.5 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.6 GO:1990523 bone regeneration(GO:1990523)
0.1 0.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 1.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 1.1 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 1.0 GO:0015705 iodide transport(GO:0015705)
0.1 0.9 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 1.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 2.0 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.4 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 1.0 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.1 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.3 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 1.5 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0043542 endothelial cell migration(GO:0043542)
0.1 1.1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.4 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.4 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.2 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.5 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.1 1.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.4 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.8 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.7 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.4 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 2.1 GO:0007141 male meiosis I(GO:0007141)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.2 GO:1902725 trans-synaptic signaling by trans-synaptic complex(GO:0099545) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.6 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.3 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.7 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 1.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 1.0 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.4 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.7 GO:0000050 urea cycle(GO:0000050)
0.0 1.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 1.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 1.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 3.6 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.5 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 1.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 1.1 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) positive regulation of developmental pigmentation(GO:0048087) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 2.1 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 1.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.4 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.1 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0099638 endosome to plasma membrane protein transport(GO:0099638)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.0 GO:0032423 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.0 0.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.1 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:1902739 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0048690 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 6.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 1.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.0 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0072717 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0002076 osteoblast development(GO:0002076)
0.0 2.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:2000275 cellular amide catabolic process(GO:0043605) regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.1 GO:0071321 positive regulation of oocyte development(GO:0060282) cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.1 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 1.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.6 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 1.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.0 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090100)
0.0 0.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.3 GO:0060384 innervation(GO:0060384)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.3 1.0 GO:0072534 perineuronal net(GO:0072534)
0.3 2.5 GO:0005610 laminin-5 complex(GO:0005610)
0.3 1.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 1.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.7 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 2.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 2.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 7.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.9 GO:0005915 zonula adherens(GO:0005915)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 1.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.0 1.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 2.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 5.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 3.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.4 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 3.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0005694 chromosome(GO:0005694)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.5 8.3 GO:0048185 activin binding(GO:0048185)
0.4 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.4 1.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 1.1 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 1.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 1.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 1.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.3 2.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 1.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 2.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.3 3.3 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.7 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 1.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 2.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.6 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 1.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.3 GO:0038064 collagen receptor activity(GO:0038064)
0.2 0.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.4 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 1.3 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 7.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.5 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.0 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 5.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.4 GO:0030547 receptor inhibitor activity(GO:0030547)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 5.0 GO:0019003 GDP binding(GO:0019003)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.3 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 2.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 2.1 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 1.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 10.4 PID BMP PATHWAY BMP receptor signaling
0.1 2.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 3.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID SHP2 PATHWAY SHP2 signaling
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 3.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 2.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME OPSINS Genes involved in Opsins
0.0 2.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 4.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.6 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 2.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines