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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ESRRB_ESRRG

Z-value: 1.74

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Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ENSG00000119715.10 ESRRB
ENSG00000196482.12 ESRRG

Activity profile of ESRRB_ESRRG motif

Sorted Z-values of ESRRB_ESRRG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_+_58179582 2.97 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr2_+_220491973 2.81 ENST00000358055.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr15_+_43886057 2.55 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43885252 2.42 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985725 2.35 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr15_+_43985084 2.34 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr8_+_86376081 2.32 ENST00000285379.5
CA2
carbonic anhydrase II
chr12_-_53320245 2.30 ENST00000552150.1
KRT8
keratin 8
chr2_-_235405168 2.19 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr2_+_220492116 2.15 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr1_+_46640750 1.82 ENST00000372003.1
TSPAN1
tetraspanin 1
chr20_+_58152524 1.77 ENST00000359926.3
PHACTR3
phosphatase and actin regulator 3
chr2_+_220492287 1.44 ENST00000273063.6
ENST00000373762.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr5_-_60140009 1.40 ENST00000505959.1
ELOVL7
ELOVL fatty acid elongase 7
chr2_+_220492373 1.37 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr10_+_118187379 1.36 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr15_-_83621435 1.33 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr9_-_117150243 1.21 ENST00000374088.3
AKNA
AT-hook transcription factor
chr3_+_113666748 1.19 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr10_-_76995769 1.12 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr10_-_76995675 1.11 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr17_-_27503770 1.03 ENST00000533112.1
MYO18A
myosin XVIIIA
chr11_+_10472223 1.02 ENST00000396554.3
ENST00000524866.1
AMPD3
adenosine monophosphate deaminase 3
chr1_+_2036149 1.01 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
PRKCZ
protein kinase C, zeta
chr10_+_81107271 0.95 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr18_-_24128496 0.88 ENST00000417602.1
KCTD1
potassium channel tetramerization domain containing 1
chr4_-_40517984 0.88 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr15_+_59730348 0.86 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr1_+_33231268 0.84 ENST00000373480.1
KIAA1522
KIAA1522
chr20_+_1875942 0.76 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr10_+_81107216 0.75 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr16_-_4588469 0.71 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr3_-_190040223 0.68 ENST00000295522.3
CLDN1
claudin 1
chr14_-_21491477 0.68 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2
NDRG family member 2
chr15_-_51535208 0.67 ENST00000405913.3
ENST00000559878.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr11_+_32851487 0.64 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr10_-_50970322 0.62 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr10_-_50970382 0.61 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr5_+_80529104 0.61 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
CKMT2
creatine kinase, mitochondrial 2 (sarcomeric)
chr17_-_29624343 0.60 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr16_+_691792 0.58 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr21_+_43639211 0.56 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr1_+_152881014 0.56 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr19_-_10697895 0.56 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr6_-_33548006 0.55 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr8_-_131028660 0.55 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
FAM49B
family with sequence similarity 49, member B
chr17_-_39928106 0.54 ENST00000540235.1
JUP
junction plakoglobin
chr16_+_777118 0.54 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr10_+_112257596 0.54 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr1_-_183560011 0.54 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr16_-_84273304 0.54 ENST00000308251.4
ENST00000568181.1
KCNG4
potassium voltage-gated channel, subfamily G, member 4
chr1_+_207226574 0.53 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr8_-_131028641 0.53 ENST00000523509.1
FAM49B
family with sequence similarity 49, member B
chr6_-_33547975 0.53 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr1_-_183559693 0.53 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr2_-_238499337 0.52 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr2_-_238499303 0.52 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr12_-_28122980 0.51 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr16_+_776936 0.50 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr1_+_16083154 0.50 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr19_+_35485682 0.49 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr2_-_238499725 0.48 ENST00000264601.3
RAB17
RAB17, member RAS oncogene family
chr4_+_24797085 0.48 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr20_-_62130474 0.48 ENST00000217182.3
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr13_-_111214015 0.48 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr2_-_238499131 0.48 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr8_+_99956759 0.47 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr22_+_30821732 0.47 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr3_-_52443799 0.46 ENST00000470173.1
ENST00000296288.5
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr19_+_15052301 0.45 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr3_-_123339343 0.45 ENST00000578202.1
MYLK
myosin light chain kinase
chr15_-_81616446 0.44 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr17_+_79670386 0.43 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr2_-_74667612 0.42 ENST00000305557.5
ENST00000233330.6
RTKN
rhotekin
chr3_-_14166316 0.42 ENST00000396914.3
ENST00000295767.5
CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr8_-_131028869 0.41 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr16_+_11038403 0.40 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr4_-_143227088 0.40 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_+_219135115 0.39 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr19_+_2249308 0.39 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr5_+_145317356 0.39 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr3_-_123339418 0.39 ENST00000583087.1
MYLK
myosin light chain kinase
chr22_+_21128167 0.39 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_+_62623621 0.38 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623544 0.38 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr9_-_130679257 0.38 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr17_-_2614927 0.38 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chrX_-_46187069 0.37 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr1_+_29213584 0.37 ENST00000343067.4
ENST00000356093.2
ENST00000398863.2
ENST00000373800.3
ENST00000349460.4
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr14_-_103987679 0.37 ENST00000553610.1
CKB
creatine kinase, brain
chr11_+_62623512 0.36 ENST00000377892.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr15_-_67813924 0.36 ENST00000559298.1
IQCH-AS1
IQCH antisense RNA 1
chr6_+_116782527 0.35 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr5_+_175085033 0.35 ENST00000377291.2
HRH2
histamine receptor H2
chr9_-_100954910 0.35 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr11_-_66139199 0.34 ENST00000357440.2
SLC29A2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr7_+_150782945 0.34 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr22_+_46546494 0.34 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
PPARA
peroxisome proliferator-activated receptor alpha
chr8_+_145149930 0.34 ENST00000318911.4
CYC1
cytochrome c-1
chr3_-_38691119 0.34 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
chr19_+_41699135 0.34 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr3_-_108672742 0.34 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr14_-_21490958 0.34 ENST00000554104.1
NDRG2
NDRG family member 2
chr14_-_21492113 0.33 ENST00000554094.1
NDRG2
NDRG family member 2
chr17_-_39743139 0.33 ENST00000167586.6
KRT14
keratin 14
chr14_-_21492251 0.33 ENST00000554398.1
NDRG2
NDRG family member 2
chr2_-_237412331 0.33 ENST00000418802.1
IQCA1
IQ motif containing with AAA domain 1
chr17_-_56350797 0.32 ENST00000577220.1
MPO
myeloperoxidase
chr6_-_107436473 0.32 ENST00000369042.1
BEND3
BEN domain containing 3
chr1_+_206858328 0.32 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr5_+_66254698 0.31 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_+_48423453 0.31 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr7_+_35756092 0.31 ENST00000458087.3
AC018647.3
AC018647.3
chr7_+_35756186 0.30 ENST00000430518.1
AC018647.3
AC018647.3
chr14_+_42076765 0.30 ENST00000298119.4
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr3_-_108672609 0.30 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr8_+_124429006 0.30 ENST00000522194.1
ENST00000523356.1
WDYHV1
WDYHV motif containing 1
chr15_+_65204075 0.30 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ANKDD1A
ankyrin repeat and death domain containing 1A
chr17_-_26876350 0.30 ENST00000470125.1
UNC119
unc-119 homolog (C. elegans)
chr8_-_110346614 0.30 ENST00000239690.4
NUDCD1
NudC domain containing 1
chr6_-_43027105 0.30 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr14_+_22985251 0.30 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr21_-_46330545 0.29 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_+_198365095 0.29 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr19_-_2328572 0.29 ENST00000252622.10
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr18_+_55816546 0.29 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr3_-_156840776 0.29 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr15_+_67814008 0.29 ENST00000557807.1
C15orf61
chromosome 15 open reading frame 61
chr9_-_118687405 0.28 ENST00000374014.3
LINC00474
long intergenic non-protein coding RNA 474
chr1_+_153388993 0.28 ENST00000368729.4
S100A7A
S100 calcium binding protein A7A
chr12_+_10366016 0.28 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_48128854 0.28 ENST00000436673.1
ENST00000429491.2
UPP1
uridine phosphorylase 1
chr6_-_43197189 0.28 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr20_-_3748363 0.28 ENST00000217195.8
C20orf27
chromosome 20 open reading frame 27
chr17_-_6616678 0.28 ENST00000381074.4
ENST00000293800.6
ENST00000572352.1
ENST00000576323.1
ENST00000573648.1
SLC13A5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr20_-_3748416 0.28 ENST00000399672.1
C20orf27
chromosome 20 open reading frame 27
chr15_+_67813406 0.28 ENST00000342683.4
C15orf61
chromosome 15 open reading frame 61
chr7_+_48128816 0.28 ENST00000395564.4
UPP1
uridine phosphorylase 1
chr9_-_138853156 0.28 ENST00000371756.3
UBAC1
UBA domain containing 1
chr8_-_100905363 0.27 ENST00000524245.1
COX6C
cytochrome c oxidase subunit VIc
chr1_+_29213678 0.27 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_-_209028300 0.27 ENST00000304502.4
CRYGA
crystallin, gamma A
chr2_+_238875597 0.27 ENST00000272930.4
ENST00000448502.1
ENST00000416292.1
ENST00000409633.1
ENST00000414443.1
ENST00000409953.1
ENST00000409332.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr17_-_73505961 0.26 ENST00000433559.2
CASKIN2
CASK interacting protein 2
chr11_-_72463421 0.26 ENST00000393609.3
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr22_-_29711645 0.26 ENST00000401450.3
RASL10A
RAS-like, family 10, member A
chr13_+_97928395 0.26 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr2_+_192141611 0.26 ENST00000392316.1
MYO1B
myosin IB
chr4_-_170947522 0.26 ENST00000361618.3
MFAP3L
microfibrillar-associated protein 3-like
chr8_-_100905925 0.26 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr5_+_34757309 0.26 ENST00000397449.1
RAI14
retinoic acid induced 14
chr7_+_48128194 0.26 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr7_+_48128316 0.26 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr17_-_7991021 0.26 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr15_+_78441663 0.25 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_-_25256368 0.25 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr16_-_3767551 0.25 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr22_-_29711704 0.25 ENST00000216101.6
RASL10A
RAS-like, family 10, member A
chr19_-_11689752 0.25 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr2_+_120189422 0.25 ENST00000306406.4
TMEM37
transmembrane protein 37
chr8_-_100905850 0.25 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr16_+_30937213 0.25 ENST00000427128.1
FBXL19
F-box and leucine-rich repeat protein 19
chr12_+_120875910 0.24 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr7_-_151433342 0.24 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_-_151433393 0.24 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr16_-_3767506 0.23 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr10_-_120925054 0.23 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
SFXN4
sideroflexin 4
chr19_-_55574538 0.23 ENST00000415061.3
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr19_+_41698927 0.23 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr7_+_56032270 0.23 ENST00000322090.3
ENST00000446778.1
GBAS
glioblastoma amplified sequence
chr19_+_1407733 0.23 ENST00000592453.1
DAZAP1
DAZ associated protein 1
chr11_-_132813566 0.23 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr8_+_99956662 0.23 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr4_-_122872909 0.22 ENST00000379645.3
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr1_-_153433120 0.22 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr11_+_6866883 0.22 ENST00000299454.4
ENST00000379831.2
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chrX_-_154033661 0.22 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr20_-_1373606 0.22 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr19_+_35629702 0.22 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr21_+_42539701 0.22 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2
beta-site APP-cleaving enzyme 2
chr4_-_120550146 0.22 ENST00000354960.3
PDE5A
phosphodiesterase 5A, cGMP-specific
chr2_+_97426631 0.22 ENST00000377075.2
CNNM4
cyclin M4
chr4_-_7069760 0.22 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr5_+_218356 0.21 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr11_+_128634589 0.21 ENST00000281428.8
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_+_145425573 0.21 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41
testis expressed 41 (non-protein coding)
chr2_-_44223138 0.21 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr3_-_167452262 0.21 ENST00000487947.2
PDCD10
programmed cell death 10
chr12_+_51632666 0.21 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr1_-_33502528 0.21 ENST00000354858.6
AK2
adenylate kinase 2
chr14_-_106622419 0.21 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr19_-_15590306 0.21 ENST00000292609.4
PGLYRP2
peptidoglycan recognition protein 2
chr3_+_179322573 0.21 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr1_-_33502441 0.21 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr1_+_46152886 0.20 ENST00000372025.4
TMEM69
transmembrane protein 69
chr4_+_41614909 0.20 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr16_+_777246 0.20 ENST00000561546.1
ENST00000564545.1
ENST00000389703.3
ENST00000567414.1
ENST00000568141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr7_-_140624499 0.20 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr17_+_13972807 0.20 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
COX10
cytochrome c oxidase assembly homolog 10 (yeast)
chr4_-_40631859 0.20 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0042938 dipeptide transport(GO:0042938)
0.6 5.7 GO:0006600 creatine metabolic process(GO:0006600)
0.6 1.7 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4 1.1 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 1.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 1.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 1.1 GO:0006218 uridine catabolic process(GO:0006218)
0.2 1.5 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2 0.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 1.1 GO:0060356 leucine import(GO:0060356)
0.2 0.7 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.6 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 0.6 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.2 0.6 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 1.0 GO:0006196 AMP catabolic process(GO:0006196)
0.2 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 2.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 1.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.7 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.4 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.5 GO:0009386 translational attenuation(GO:0009386)
0.1 1.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.3 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.3 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 5.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.3 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.2 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.2 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.2 GO:0018013 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.7 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.4 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 1.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 1.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0001878 response to yeast(GO:0001878)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.0 GO:0045730 respiratory burst(GO:0045730)
0.0 0.7 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0097286 iron ion import(GO:0097286)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:1904044 response to aldosterone(GO:1904044)
0.0 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.0 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 1.7 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0032010 phagolysosome(GO:0032010)
0.1 1.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 2.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 1.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 3.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 1.7 GO:0030175 filopodium(GO:0030175)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 6.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.7 GO:0004111 creatine kinase activity(GO:0004111)
0.3 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.3 5.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.2 1.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 0.6 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 0.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 5.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 1.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.3 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.1 0.5 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 1.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.0 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.0 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 2.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0032052 bile acid binding(GO:0032052)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849) virion binding(GO:0046790)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 3.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 5.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 10.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type