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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for ETV2

Z-value: 2.60

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Transcription factors associated with ETV2

Gene Symbol Gene ID Gene Info
ETV2
ENSG00000105672.10 ETV2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV2hg19_v2_chr19_+_36132631_361326950.772.7e-02Click!

Activity profile of ETV2 motif

Sorted Z-values of ETV2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_238322800 2.05 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
 COL6A3
 collagen, type VI, alpha 3
chr2_-_238323007 2.03 ENST00000295550.4
 COL6A3
 collagen, type VI, alpha 3
chr10_+_69865866 1.93 ENST00000354393.2
 MYPN
 myopalladin
chrX_+_70586140 1.93 ENST00000276072.3
 TAF1
 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr2_-_238322770 1.91 ENST00000472056.1
 COL6A3
 collagen, type VI, alpha 3
chr1_+_183774240 1.75 ENST00000360851.3
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr4_-_39640700 1.73 ENST00000295958.5
 SMIM14
 small integral membrane protein 14
chr13_-_33760216 1.56 ENST00000255486.4
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr19_-_8942962 1.44 ENST00000601372.1
 ZNF558
 zinc finger protein 558
chr4_+_14113592 1.30 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
 LINC01085
 long intergenic non-protein coding RNA 1085
chr4_-_39640513 1.22 ENST00000511809.1
ENST00000505729.1
 SMIM14
 small integral membrane protein 14
chr1_-_232697304 1.20 ENST00000366630.1
 SIPA1L2
 signal-induced proliferation-associated 1 like 2
chr1_+_22351977 1.12 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
 LINC00339
 long intergenic non-protein coding RNA 339
chr5_+_67584174 1.11 ENST00000320694.8
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_70586082 1.06 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
 TAF1
 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr1_+_162467595 1.05 ENST00000538489.1
ENST00000489294.1
 UHMK1
 U2AF homology motif (UHM) kinase 1
chr4_-_39529180 1.04 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
 UGDH
 UDP-glucose 6-dehydrogenase
chrX_+_55478538 1.04 ENST00000342972.1
 MAGEH1
 melanoma antigen family H, 1
chr5_+_180650271 1.03 ENST00000351937.5
ENST00000315073.5
 TRIM41
 tripartite motif containing 41
chr2_+_120770581 1.03 ENST00000263713.5
 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
chr5_+_134240800 1.01 ENST00000512783.1
 PCBD2
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr3_+_69985734 1.00 ENST00000314557.6
ENST00000394351.3
 MITF
 microphthalmia-associated transcription factor
chr8_+_38586068 1.00 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr2_+_102721023 0.96 ENST00000409589.1
ENST00000409329.1
 IL1R1
 interleukin 1 receptor, type I
chr14_-_75593708 0.95 ENST00000557673.1
ENST00000238616.5
 NEK9
 NIMA-related kinase 9
chr7_+_100770328 0.93 ENST00000223095.4
ENST00000445463.2
 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr14_-_106406090 0.86 ENST00000390593.2
 IGHV6-1
 immunoglobulin heavy variable 6-1
chr8_+_38585704 0.85 ENST00000519416.1
ENST00000520615.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr11_-_119293872 0.85 ENST00000524970.1
 THY1
 Thy-1 cell surface antigen
chr17_-_53809473 0.83 ENST00000575734.1
 TMEM100
 transmembrane protein 100
chr7_-_19157248 0.80 ENST00000242261.5
 TWIST1
 twist family bHLH transcription factor 1
chr6_+_31620191 0.77 ENST00000375918.2
ENST00000375920.4
 APOM
 apolipoprotein M
chr6_-_30710510 0.75 ENST00000376389.3
 FLOT1
 flotillin 1
chr1_-_145470383 0.74 ENST00000369314.1
ENST00000369313.3
 POLR3GL
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr6_-_30710447 0.74 ENST00000456573.2
 FLOT1
 flotillin 1
chr1_-_36789755 0.73 ENST00000270824.1
 EVA1B
 eva-1 homolog B (C. elegans)
chr10_-_50747064 0.72 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
 ERCC6
PGBD3
ERCC6-PGBD3
 excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr16_-_3355645 0.70 ENST00000396862.1
ENST00000573608.1
 TIGD7
 tigger transposable element derived 7
chr15_+_71185148 0.70 ENST00000443425.2
ENST00000560755.1
 LRRC49
 leucine rich repeat containing 49
chr12_+_108908962 0.69 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
 FICD
 FIC domain containing
chr6_+_30524663 0.69 ENST00000376560.3
 PRR3
 proline rich 3
chr20_-_34542548 0.69 ENST00000305978.2
 SCAND1
 SCAN domain containing 1
chr16_+_20817761 0.66 ENST00000568046.1
ENST00000261377.6
 AC004381.6
 Putative RNA exonuclease NEF-sp
chr2_+_219536749 0.65 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
 STK36
 serine/threonine kinase 36
chr4_-_57976544 0.65 ENST00000295666.4
ENST00000537922.1
 IGFBP7
 insulin-like growth factor binding protein 7
chr19_-_44860820 0.64 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
 ZNF112
 zinc finger protein 112
chr19_+_32896697 0.64 ENST00000586987.1
 DPY19L3
 dpy-19-like 3 (C. elegans)
chr6_+_30525051 0.63 ENST00000376557.3
 PRR3
 proline rich 3
chr11_+_6502675 0.62 ENST00000254616.6
ENST00000530751.1
 TIMM10B
 translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr6_-_11382478 0.62 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
chrX_+_51546103 0.62 ENST00000375772.3
 MAGED1
 melanoma antigen family D, 1
chr12_-_105630016 0.61 ENST00000258530.3
 APPL2
 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr14_+_100842735 0.60 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
 WDR25
 WD repeat domain 25
chr4_-_39529049 0.60 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
 UGDH
 UDP-glucose 6-dehydrogenase
chr7_+_134528635 0.60 ENST00000445569.2
 CALD1
 caldesmon 1
chr11_+_131781290 0.60 ENST00000425719.2
ENST00000374784.1
 NTM
 neurotrimin
chr5_-_127674883 0.60 ENST00000507835.1
 FBN2
 fibrillin 2
chr7_+_7606497 0.60 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
 MIOS
 missing oocyte, meiosis regulator, homolog (Drosophila)
chr16_+_20817839 0.60 ENST00000348433.6
ENST00000568501.1
ENST00000566276.1
 AC004381.6
 Putative RNA exonuclease NEF-sp
chrX_+_54834791 0.59 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
 MAGED2
 melanoma antigen family D, 2
chr12_+_7053172 0.58 ENST00000229281.5
 C12orf57
 chromosome 12 open reading frame 57
chr21_+_45285050 0.58 ENST00000291572.8
 AGPAT3
 1-acylglycerol-3-phosphate O-acyltransferase 3
chr12_+_7052974 0.58 ENST00000544681.1
ENST00000537087.1
 C12orf57
 chromosome 12 open reading frame 57
chr12_-_15374343 0.58 ENST00000256953.2
ENST00000546331.1
 RERG
 RAS-like, estrogen-regulated, growth inhibitor
chr12_+_120105558 0.57 ENST00000229328.5
ENST00000541640.1
 PRKAB1
 protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr5_+_173315283 0.57 ENST00000265085.5
 CPEB4
 cytoplasmic polyadenylation element binding protein 4
chr17_-_7218631 0.57 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
 GPS2
 G protein pathway suppressor 2
chr1_-_161039456 0.56 ENST00000368016.3
 ARHGAP30
 Rho GTPase activating protein 30
chr3_+_9944492 0.56 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
 IL17RE
 interleukin 17 receptor E
chr8_-_122653630 0.55 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr1_-_149900122 0.55 ENST00000271628.8
 SF3B4
 splicing factor 3b, subunit 4, 49kDa
chr22_+_22020273 0.54 ENST00000412327.1
ENST00000335025.8
ENST00000398831.3
ENST00000492445.2
ENST00000458567.1
ENST00000406385.1
 PPIL2
 peptidylprolyl isomerase (cyclophilin)-like 2
chr8_+_182368 0.54 ENST00000522866.1
ENST00000398612.1
 ZNF596
 zinc finger protein 596
chr12_+_75874984 0.54 ENST00000550491.1
 GLIPR1
 GLI pathogenesis-related 1
chr12_-_105629852 0.54 ENST00000551662.1
ENST00000553097.1
 APPL2
 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr14_-_89021077 0.53 ENST00000556564.1
 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
chr10_+_116581503 0.53 ENST00000369248.4
ENST00000369250.3
ENST00000369246.1
 FAM160B1
 family with sequence similarity 160, member B1
chr12_-_133532864 0.53 ENST00000536932.1
ENST00000360187.4
ENST00000392321.3
 CHFR
ZNF605
 checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
zinc finger protein 605
chr1_-_109618566 0.53 ENST00000338366.5
 TAF13
 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr15_+_71184931 0.53 ENST00000560369.1
ENST00000260382.5
 LRRC49
 leucine rich repeat containing 49
chr3_+_52321827 0.53 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
 GLYCTK
 glycerate kinase
chr3_+_9944303 0.53 ENST00000421412.1
ENST00000295980.3
 IL17RE
 interleukin 17 receptor E
chr15_-_35261996 0.53 ENST00000156471.5
 AQR
 aquarius intron-binding spliceosomal factor
chr3_-_128880125 0.52 ENST00000393295.3
 ISY1
 ISY1 splicing factor homolog (S. cerevisiae)
chr5_+_147763498 0.52 ENST00000340253.5
 FBXO38
 F-box protein 38
chr14_+_29234870 0.52 ENST00000382535.3
 FOXG1
 forkhead box G1
chr19_-_45927097 0.51 ENST00000340192.7
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr2_-_85839146 0.51 ENST00000306336.5
ENST00000409734.3
 C2orf68
 chromosome 2 open reading frame 68
chr12_+_7053228 0.51 ENST00000540506.2
 C12orf57
 chromosome 12 open reading frame 57
chr19_-_10446449 0.51 ENST00000592439.1
 ICAM3
 intercellular adhesion molecule 3
chr2_+_201981119 0.50 ENST00000395148.2
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chrX_-_48931648 0.50 ENST00000376386.3
ENST00000376390.4
 PRAF2
 PRA1 domain family, member 2
chr5_+_147763539 0.50 ENST00000296701.6
ENST00000394370.3
 FBXO38
 F-box protein 38
chrX_+_77166172 0.50 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr18_-_60987220 0.50 ENST00000398117.1
 BCL2
 B-cell CLL/lymphoma 2
chr16_+_20818020 0.50 ENST00000564274.1
ENST00000563068.1
 AC004381.6
 Putative RNA exonuclease NEF-sp
chr19_+_32896646 0.49 ENST00000392250.2
 DPY19L3
 dpy-19-like 3 (C. elegans)
chr17_+_1674982 0.49 ENST00000572048.1
ENST00000573763.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr20_-_2821756 0.48 ENST00000356872.3
ENST00000439542.1
 PCED1A
 PC-esterase domain containing 1A
chr2_-_63815628 0.47 ENST00000409562.3
 WDPCP
 WD repeat containing planar cell polarity effector
chr5_-_107717058 0.46 ENST00000359660.5
 FBXL17
 F-box and leucine-rich repeat protein 17
chr19_+_44529479 0.46 ENST00000587846.1
ENST00000187879.8
ENST00000391960.3
 ZNF222
 zinc finger protein 222
chr19_+_37569314 0.46 ENST00000304239.7
ENST00000589245.1
ENST00000337995.3
 ZNF420
 zinc finger protein 420
chr16_-_3493528 0.46 ENST00000301744.4
 ZNF597
 zinc finger protein 597
chr20_+_62612470 0.46 ENST00000266079.4
ENST00000535781.1
 PRPF6
 pre-mRNA processing factor 6
chr13_-_43566301 0.46 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
 EPSTI1
 epithelial stromal interaction 1 (breast)
chr10_+_104614008 0.45 ENST00000369883.3
 C10orf32
 chromosome 10 open reading frame 32
chr11_+_72281681 0.44 ENST00000450804.3
 RP11-169D4.1
 RP11-169D4.1
chr12_+_75874580 0.44 ENST00000456650.3
 GLIPR1
 GLI pathogenesis-related 1
chr2_+_120770645 0.44 ENST00000443902.2
 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
chr10_+_104613980 0.44 ENST00000339834.5
 C10orf32
 chromosome 10 open reading frame 32
chrX_+_85969626 0.44 ENST00000484479.1
 DACH2
 dachshund homolog 2 (Drosophila)
chr17_+_59489112 0.43 ENST00000335108.2
 C17orf82
 chromosome 17 open reading frame 82
chrX_+_54947229 0.43 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
 TRO
 trophinin
chr19_-_48752812 0.43 ENST00000359009.4
 CARD8
 caspase recruitment domain family, member 8
chr5_+_158690089 0.43 ENST00000296786.6
 UBLCP1
 ubiquitin-like domain containing CTD phosphatase 1
chr19_+_44764031 0.43 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
 ZNF233
 zinc finger protein 233
chr1_+_44679113 0.42 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
 DMAP1
 DNA methyltransferase 1 associated protein 1
chr1_+_65886244 0.41 ENST00000344610.8
 LEPR
 leptin receptor
chr1_-_28969517 0.41 ENST00000263974.4
ENST00000373824.4
 TAF12
 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr6_-_27440837 0.41 ENST00000211936.6
 ZNF184
 zinc finger protein 184
chr2_+_219537015 0.41 ENST00000440309.1
ENST00000424080.1
 STK36
 serine/threonine kinase 36
chr20_+_43595115 0.40 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
 STK4
 serine/threonine kinase 4
chr19_-_44405941 0.40 ENST00000587128.1
 RP11-15A1.3
 RP11-15A1.3
chr1_-_10003372 0.40 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
 LZIC
 leucine zipper and CTNNBIP1 domain containing
chr5_+_159436120 0.40 ENST00000522793.1
ENST00000231238.5
 TTC1
 tetratricopeptide repeat domain 1
chr2_-_38830030 0.40 ENST00000410076.1
 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
chr11_-_47600320 0.40 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
 KBTBD4
 kelch repeat and BTB (POZ) domain containing 4
chr1_+_84609944 0.40 ENST00000370685.3
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr1_+_44679159 0.40 ENST00000315913.5
ENST00000372289.2
 DMAP1
 DNA methyltransferase 1 associated protein 1
chr1_-_167059830 0.40 ENST00000367868.3
 GPA33
 glycoprotein A33 (transmembrane)
chr2_-_224467093 0.40 ENST00000305409.2
 SCG2
 secretogranin II
chr12_-_53715328 0.40 ENST00000547757.1
ENST00000394384.3
ENST00000209873.4
 AAAS
 achalasia, adrenocortical insufficiency, alacrimia
chr7_-_74267836 0.39 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
 GTF2IRD2
 GTF2I repeat domain containing 2
chr3_+_180319918 0.39 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
 TTC14
 tetratricopeptide repeat domain 14
chrX_-_153775426 0.39 ENST00000393562.2
 G6PD
 glucose-6-phosphate dehydrogenase
chr1_+_15632231 0.39 ENST00000375997.4
ENST00000524761.1
ENST00000375995.3
ENST00000401090.2
 FHAD1
 forkhead-associated (FHA) phosphopeptide binding domain 1
chr17_+_26989109 0.39 ENST00000314616.6
ENST00000347486.4
 SUPT6H
 suppressor of Ty 6 homolog (S. cerevisiae)
chr19_-_44439387 0.39 ENST00000269973.5
 ZNF45
 zinc finger protein 45
chr6_-_27440460 0.39 ENST00000377419.1
 ZNF184
 zinc finger protein 184
chr2_+_201981527 0.39 ENST00000441224.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr19_-_48753104 0.39 ENST00000447740.2
 CARD8
 caspase recruitment domain family, member 8
chr5_+_140762268 0.38 ENST00000518325.1
 PCDHGA7
 protocadherin gamma subfamily A, 7
chr5_+_178487354 0.38 ENST00000315475.6
 ZNF354C
 zinc finger protein 354C
chrX_-_134429952 0.38 ENST00000370764.1
 ZNF75D
 zinc finger protein 75D
chr2_-_233415220 0.38 ENST00000408957.3
 TIGD1
 tigger transposable element derived 1
chr20_+_44044717 0.38 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
 PIGT
 phosphatidylinositol glycan anchor biosynthesis, class T
chr12_+_94071129 0.38 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
 CRADD
 CASP2 and RIPK1 domain containing adaptor with death domain
chr20_-_44485835 0.38 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
 ACOT8
 acyl-CoA thioesterase 8
chr3_-_52002403 0.38 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
 PCBP4
 poly(rC) binding protein 4
chrX_-_15872914 0.38 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
 AP1S2
 adaptor-related protein complex 1, sigma 2 subunit
chr16_-_31085514 0.37 ENST00000300849.4
 ZNF668
 zinc finger protein 668
chr6_-_49430886 0.37 ENST00000274813.3
 MUT
 methylmalonyl CoA mutase
chr3_+_69985792 0.37 ENST00000531774.1
 MITF
 microphthalmia-associated transcription factor
chr12_-_110511424 0.37 ENST00000548191.1
 C12orf76
 chromosome 12 open reading frame 76
chr4_+_2470664 0.37 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
 RNF4
 ring finger protein 4
chr9_-_91793675 0.37 ENST00000375835.4
ENST00000375830.1
 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3
chrX_+_152086373 0.37 ENST00000318529.8
 ZNF185
 zinc finger protein 185 (LIM domain)
chr5_+_140723601 0.37 ENST00000253812.6
 PCDHGA3
 protocadherin gamma subfamily A, 3
chr16_+_3355472 0.37 ENST00000574298.1
 ZNF75A
 zinc finger protein 75a
chr5_+_130506475 0.37 ENST00000379380.4
 LYRM7
 LYR motif containing 7
chr7_+_44084262 0.37 ENST00000456905.1
ENST00000440166.1
ENST00000452943.1
ENST00000468694.1
ENST00000494774.1
ENST00000490734.2
 DBNL
 drebrin-like
chr1_-_1509931 0.37 ENST00000359060.4
 SSU72
 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
chr1_+_43855560 0.36 ENST00000562955.1
 SZT2
 seizure threshold 2 homolog (mouse)
chr9_-_72374848 0.36 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
 PTAR1
 protein prenyltransferase alpha subunit repeat containing 1
chr15_-_85197501 0.36 ENST00000434634.2
 WDR73
 WD repeat domain 73
chr4_-_39033963 0.36 ENST00000381938.3
 TMEM156
 transmembrane protein 156
chr7_+_44084233 0.36 ENST00000448521.1
 DBNL
 drebrin-like
chr6_-_168476511 0.36 ENST00000440994.2
 FRMD1
 FERM domain containing 1
chr2_+_201980961 0.36 ENST00000342795.5
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chrX_+_47444613 0.36 ENST00000445623.1
 TIMP1
 TIMP metallopeptidase inhibitor 1
chr11_-_47600549 0.36 ENST00000430070.2
 KBTBD4
 kelch repeat and BTB (POZ) domain containing 4
chr7_-_99679324 0.35 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
 ZNF3
 zinc finger protein 3
chr20_+_43104508 0.35 ENST00000262605.4
ENST00000372904.3
 TTPAL
 tocopherol (alpha) transfer protein-like
chr19_-_40596767 0.35 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
 ZNF780A
 zinc finger protein 780A
chr5_-_130970723 0.35 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
chr1_-_43855479 0.35 ENST00000290663.6
ENST00000372457.4
 MED8
 mediator complex subunit 8
chr12_+_53689309 0.35 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
 PFDN5
 prefoldin subunit 5
chr19_+_9473676 0.35 ENST00000343499.4
ENST00000592912.1
 ZNF177
 zinc finger protein 177
chr6_+_147525541 0.35 ENST00000367481.3
ENST00000546097.1
 STXBP5
 syntaxin binding protein 5 (tomosyn)
chr14_-_74417096 0.35 ENST00000286544.3
 FAM161B
 family with sequence similarity 161, member B
chr2_+_201980827 0.35 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr11_-_82708519 0.35 ENST00000534301.1
 RAB30
 RAB30, member RAS oncogene family
chr12_-_10605929 0.35 ENST00000347831.5
ENST00000359151.3
 KLRC1
 killer cell lectin-like receptor subfamily C, member 1
chr17_+_42264395 0.34 ENST00000587989.1
ENST00000590235.1
 TMUB2
 transmembrane and ubiquitin-like domain containing 2
chr1_-_101360331 0.34 ENST00000416479.1
ENST00000370113.3
 EXTL2
 exostosin-like glycosyltransferase 2
chr5_-_143550241 0.34 ENST00000522203.1
 YIPF5
 Yip1 domain family, member 5
chr17_-_79817091 0.34 ENST00000570907.1
 P4HB
 prolyl 4-hydroxylase, beta polypeptide
chr5_+_139781393 0.34 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
 ANKHD1
 ankyrin repeat and KH domain containing 1
chr14_+_76618242 0.34 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
 GPATCH2L
 G patch domain containing 2-like
chr12_+_94071341 0.34 ENST00000542893.2
 CRADD
 CASP2 and RIPK1 domain containing adaptor with death domain
chr19_-_44809121 0.34 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
 ZNF235
 zinc finger protein 235
chr12_+_56401268 0.33 ENST00000262032.5
 IKZF4
 IKAROS family zinc finger 4 (Eos)
chr20_+_1099233 0.33 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
 PSMF1
 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr1_+_158978768 0.33 ENST00000447473.2
 IFI16
 interferon, gamma-inducible protein 16
chr17_+_7482785 0.33 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
 CD68
 CD68 molecule
chr20_-_2821271 0.33 ENST00000448755.1
ENST00000360652.2
 PCED1A
 PC-esterase domain containing 1A
chr6_-_149969829 0.33 ENST00000367411.2
 KATNA1
 katanin p60 (ATPase containing) subunit A 1
chr17_-_33288467 0.33 ENST00000436961.3
 CCT6B
 chaperonin containing TCP1, subunit 6B (zeta 2)
chr19_-_53606604 0.33 ENST00000599056.1
ENST00000599247.1
ENST00000355147.5
ENST00000429604.1
ENST00000418871.1
ENST00000599637.1
 ZNF160
 zinc finger protein 160

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0036369 transcription factor catabolic process(GO:0036369)
0.3 1.0 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 0.9 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 1.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.3 0.8 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 1.7 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.9 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 1.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 1.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 0.8 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 0.6 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.2 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.2 1.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 0.5 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 1.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.6 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 1.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.8 GO:0090521 regulation of embryonic cell shape(GO:0016476) septin cytoskeleton organization(GO:0032185) glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.6 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.5 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.3 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 1.0 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 1.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.6 GO:0051414 response to cortisol(GO:0051414)
0.1 0.8 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.5 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.2 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.3 GO:0072204 pro-T cell differentiation(GO:0002572) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of DNA demethylation(GO:1901536)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 6.0 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.6 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.8 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.9 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.0 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.6 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.2 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.9 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.1 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.0 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.2 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0097325 cardiac right atrium morphogenesis(GO:0003213) melanocyte proliferation(GO:0097325)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 1.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.3 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.0 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.9 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 1.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.9 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:0070535 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0021539 subthalamus development(GO:0021539)
0.0 0.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0034205 beta-amyloid formation(GO:0034205)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500) regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.0 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 1.2 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0035268 protein mannosylation(GO:0035268)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.6 GO:0008038 neuron recognition(GO:0008038)
0.0 0.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.5 GO:0035904 aorta development(GO:0035904)
0.0 0.2 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 1.4 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.3 0.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.4 GO:1990923 PET complex(GO:1990923)
0.1 0.5 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 1.5 GO:0016600 flotillin complex(GO:0016600)
0.1 0.1 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
0.1 1.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 3.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.3 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.7 GO:0044447 axoneme part(GO:0044447)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.9 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0097346 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 2.8 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.3 1.0 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.3 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 0.6 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.2 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 0.5 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.9 GO:0032089 NACHT domain binding(GO:0032089)
0.1 1.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.1 GO:0043559 insulin binding(GO:0043559)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.7 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0000406 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 1.2 GO:0070513 death domain binding(GO:0070513)
0.1 0.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 1.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.1 7.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 1.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.3 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.2 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 4.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.1 PID AURORA A PATHWAY Aurora A signaling
0.0 1.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.9 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 4.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 8.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway