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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for EZH2

Z-value: 0.41

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Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
EZH2
ENSG00000106462.6 EZH2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg19_v2_chr7_-_148580563_148580601-0.206.3e-01Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_43885252 0.87 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
 CKMT1B
 creatine kinase, mitochondrial 1B
chr19_-_51456344 0.86 ENST00000336334.3
ENST00000593428.1
 KLK5
 kallikrein-related peptidase 5
chr10_-_105845674 0.86 ENST00000353479.5
ENST00000369733.3
 COL17A1
 collagen, type XVII, alpha 1
chr7_+_69064300 0.79 ENST00000342771.4
 AUTS2
 autism susceptibility candidate 2
chr1_+_86889769 0.77 ENST00000370565.4
 CLCA2
 chloride channel accessory 2
chr15_+_43985084 0.68 ENST00000434505.1
ENST00000411750.1
 CKMT1A
 creatine kinase, mitochondrial 1A
chr12_-_6483969 0.61 ENST00000396966.2
 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
chr12_-_6484376 0.59 ENST00000360168.3
ENST00000358945.3
 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
chr7_-_41740181 0.57 ENST00000442711.1
 INHBA
 inhibin, beta A
chr1_-_153588765 0.57 ENST00000368701.1
ENST00000344616.2
 S100A14
 S100 calcium binding protein A14
chr19_-_36004543 0.53 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
 DMKN
 dermokine
chr19_-_36001286 0.53 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
 DMKN
 dermokine
chr8_-_41166953 0.52 ENST00000220772.3
 SFRP1
 secreted frizzled-related protein 1
chr1_-_209824643 0.52 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr15_+_43886057 0.52 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
 CKMT1B
 creatine kinase, mitochondrial 1B
chr19_-_35992780 0.49 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
 DMKN
 dermokine
chr7_-_22233442 0.48 ENST00000401957.2
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_153588334 0.48 ENST00000476873.1
 S100A14
 S100 calcium binding protein A14
chr13_-_20805109 0.41 ENST00000241124.6
 GJB6
 gap junction protein, beta 6, 30kDa
chr12_-_6484715 0.39 ENST00000228916.2
 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
chr19_+_35606692 0.39 ENST00000406242.3
ENST00000454903.2
 FXYD3
 FXYD domain containing ion transport regulator 3
chr15_+_43985725 0.35 ENST00000413453.2
 CKMT1A
 creatine kinase, mitochondrial 1A
chr18_+_29027696 0.33 ENST00000257189.4
 DSG3
 desmoglein 3
chr19_-_51522955 0.33 ENST00000358789.3
 KLK10
 kallikrein-related peptidase 10
chr2_-_31637560 0.33 ENST00000379416.3
 XDH
 xanthine dehydrogenase
chr2_-_113594279 0.33 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B
 interleukin 1, beta
chr19_-_51456321 0.32 ENST00000391809.2
 KLK5
 kallikrein-related peptidase 5
chr8_+_102504651 0.32 ENST00000251808.3
ENST00000521085.1
 GRHL2
 grainyhead-like 2 (Drosophila)
chrX_-_153141302 0.31 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
 L1CAM
 L1 cell adhesion molecule
chr17_+_55183261 0.29 ENST00000576295.1
 AKAP1
 A kinase (PRKA) anchor protein 1
chr7_+_145813453 0.29 ENST00000361727.3
 CNTNAP2
 contactin associated protein-like 2
chr1_+_2036149 0.28 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
 PRKCZ
 protein kinase C, zeta
chr3_+_189507432 0.27 ENST00000354600.5
 TP63
 tumor protein p63
chr1_+_233749739 0.27 ENST00000366621.3
 KCNK1
 potassium channel, subfamily K, member 1
chr18_+_47088401 0.27 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
 LIPG
 lipase, endothelial
chr11_-_119993734 0.26 ENST00000533302.1
 TRIM29
 tripartite motif containing 29
chr1_+_109792641 0.26 ENST00000271332.3
 CELSR2
 cadherin, EGF LAG seven-pass G-type receptor 2
chr12_-_8815299 0.26 ENST00000535336.1
 MFAP5
 microfibrillar associated protein 5
chr11_-_66496430 0.26 ENST00000533211.1
 SPTBN2
 spectrin, beta, non-erythrocytic 2
chr11_-_5323226 0.26 ENST00000380224.1
 OR51B4
 olfactory receptor, family 51, subfamily B, member 4
chr4_+_81118647 0.26 ENST00000415738.2
 PRDM8
 PR domain containing 8
chr6_-_136847610 0.26 ENST00000454590.1
ENST00000432797.2
 MAP7
 microtubule-associated protein 7
chr2_-_216003127 0.26 ENST00000412081.1
ENST00000272895.7
 ABCA12
 ATP-binding cassette, sub-family A (ABC1), member 12
chr14_-_54423529 0.25 ENST00000245451.4
ENST00000559087.1
 BMP4
 bone morphogenetic protein 4
chr11_+_128563652 0.25 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr4_+_24797085 0.24 ENST00000382120.3
 SOD3
 superoxide dismutase 3, extracellular
chr1_+_2004901 0.24 ENST00000400921.2
 PRKCZ
 protein kinase C, zeta
chr5_+_145317356 0.24 ENST00000511217.1
 SH3RF2
 SH3 domain containing ring finger 2
chr5_+_167181917 0.24 ENST00000519204.1
 TENM2
 teneurin transmembrane protein 2
chr12_-_53343602 0.23 ENST00000546897.1
ENST00000552551.1
 KRT8
 keratin 8
chr14_+_22580233 0.23 ENST00000390454.2
 TRAV25
 T cell receptor alpha variable 25
chr1_+_2005425 0.23 ENST00000461106.2
 PRKCZ
 protein kinase C, zeta
chr3_-_197300194 0.23 ENST00000358186.2
ENST00000431056.1
 BDH1
 3-hydroxybutyrate dehydrogenase, type 1
chr2_+_220325441 0.22 ENST00000396688.1
 SPEG
 SPEG complex locus
chr10_-_116444371 0.22 ENST00000533213.2
ENST00000369252.4
 ABLIM1
 actin binding LIM protein 1
chr12_-_28125638 0.22 ENST00000545234.1
 PTHLH
 parathyroid hormone-like hormone
chr19_-_51504852 0.22 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
 KLK8
 kallikrein-related peptidase 8
chr6_-_31550192 0.21 ENST00000429299.2
ENST00000446745.2
 LTB
 lymphotoxin beta (TNF superfamily, member 3)
chr16_-_31147020 0.21 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
 PRSS8
 protease, serine, 8
chr19_+_35607166 0.21 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
 FXYD3
 FXYD domain containing ion transport regulator 3
chr8_+_56792355 0.20 ENST00000519728.1
 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr14_-_99737565 0.20 ENST00000357195.3
 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
chr8_+_56792377 0.20 ENST00000520220.2
 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chrX_-_151619746 0.20 ENST00000370314.4
 GABRA3
 gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr19_-_4338783 0.20 ENST00000601482.1
ENST00000600324.1
 STAP2
 signal transducing adaptor family member 2
chr1_+_209859510 0.20 ENST00000367028.2
ENST00000261465.1
 HSD11B1
 hydroxysteroid (11-beta) dehydrogenase 1
chr3_+_111717511 0.20 ENST00000478951.1
ENST00000393917.2
 TAGLN3
 transgelin 3
chr1_+_95286151 0.20 ENST00000467909.1
ENST00000422520.2
ENST00000532427.1
 SLC44A3
 solute carrier family 44, member 3
chr1_+_152881014 0.20 ENST00000368764.3
ENST00000392667.2
 IVL
 involucrin
chr2_+_45168875 0.20 ENST00000260653.3
 SIX3
 SIX homeobox 3
chr7_+_86273700 0.19 ENST00000546348.1
 GRM3
 glutamate receptor, metabotropic 3
chr5_-_60140009 0.19 ENST00000505959.1
 ELOVL7
 ELOVL fatty acid elongase 7
chr14_-_67859422 0.19 ENST00000556532.1
 PLEK2
 pleckstrin 2
chr2_-_165424973 0.19 ENST00000543549.1
 GRB14
 growth factor receptor-bound protein 14
chr12_+_83080659 0.19 ENST00000321196.3
 TMTC2
 transmembrane and tetratricopeptide repeat containing 2
chr1_-_147245484 0.19 ENST00000271348.2
 GJA5
 gap junction protein, alpha 5, 40kDa
chr12_+_101188547 0.18 ENST00000546991.1
ENST00000392979.3
 ANO4
 anoctamin 4
chr6_+_125540951 0.18 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chr6_-_47010061 0.18 ENST00000371253.2
 GPR110
 G protein-coupled receptor 110
chr11_-_44331679 0.18 ENST00000329255.3
 ALX4
 ALX homeobox 4
chr20_-_42815733 0.18 ENST00000342272.3
 JPH2
 junctophilin 2
chr12_-_24102576 0.18 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
 SOX5
 SRY (sex determining region Y)-box 5
chr12_+_66218212 0.18 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
 HMGA2
 high mobility group AT-hook 2
chr2_+_102608306 0.18 ENST00000332549.3
 IL1R2
 interleukin 1 receptor, type II
chr6_-_41130841 0.18 ENST00000373122.4
 TREM2
 triggering receptor expressed on myeloid cells 2
chr5_-_141249154 0.18 ENST00000357517.5
ENST00000536585.1
 PCDH1
 protocadherin 1
chr17_-_56494882 0.17 ENST00000584437.1
 RNF43
 ring finger protein 43
chr6_-_136847099 0.17 ENST00000438100.2
 MAP7
 microtubule-associated protein 7
chr17_-_56494908 0.17 ENST00000577716.1
 RNF43
 ring finger protein 43
chr17_-_56494713 0.17 ENST00000407977.2
 RNF43
 ring finger protein 43
chr14_-_99737822 0.17 ENST00000345514.2
ENST00000443726.2
 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
chrX_-_100662881 0.17 ENST00000218516.3
 GLA
 galactosidase, alpha
chr3_+_111630451 0.17 ENST00000495180.1
 PHLDB2
 pleckstrin homology-like domain, family B, member 2
chr3_+_193853927 0.17 ENST00000232424.3
 HES1
 hes family bHLH transcription factor 1
chr14_-_23623577 0.17 ENST00000422941.2
ENST00000453702.1
 SLC7A8
 solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr6_+_25279651 0.17 ENST00000329474.6
 LRRC16A
 leucine rich repeat containing 16A
chr6_+_53659746 0.16 ENST00000370888.1
 LRRC1
 leucine rich repeat containing 1
chr6_+_13925318 0.16 ENST00000423553.2
ENST00000537388.1
 RNF182
 ring finger protein 182
chr4_-_80994210 0.16 ENST00000403729.2
 ANTXR2
 anthrax toxin receptor 2
chr5_+_140345820 0.16 ENST00000289269.5
 PCDHAC2
 protocadherin alpha subfamily C, 2
chr12_+_101188718 0.16 ENST00000299222.9
ENST00000392977.3
 ANO4
 anoctamin 4
chr11_-_124311054 0.16 ENST00000328064.2
 OR8B8
 olfactory receptor, family 8, subfamily B, member 8
chr8_-_127570603 0.16 ENST00000304916.3
 FAM84B
 family with sequence similarity 84, member B
chr15_-_88799948 0.15 ENST00000394480.2
 NTRK3
 neurotrophic tyrosine kinase, receptor, type 3
chr9_+_133971863 0.15 ENST00000372309.3
 AIF1L
 allograft inflammatory factor 1-like
chr11_-_5462744 0.15 ENST00000380211.1
 OR51I1
 olfactory receptor, family 51, subfamily I, member 1
chr9_+_133971909 0.15 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
 AIF1L
 allograft inflammatory factor 1-like
chr1_-_116311402 0.15 ENST00000261448.5
 CASQ2
 calsequestrin 2 (cardiac muscle)
chr9_-_107690420 0.14 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
 ABCA1
 ATP-binding cassette, sub-family A (ABC1), member 1
chr8_+_128748308 0.14 ENST00000377970.2
 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
chr18_-_47721447 0.14 ENST00000285039.7
 MYO5B
 myosin VB
chr5_-_35230434 0.14 ENST00000504500.1
 PRLR
 prolactin receptor
chr12_+_20848282 0.14 ENST00000545604.1
 SLCO1C1
 solute carrier organic anion transporter family, member 1C1
chr12_+_20848377 0.14 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
 SLCO1C1
 solute carrier organic anion transporter family, member 1C1
chr12_-_71031220 0.14 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr3_+_111717600 0.14 ENST00000273368.4
 TAGLN3
 transgelin 3
chr19_+_51728316 0.14 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
 CD33
 CD33 molecule
chrX_-_152989798 0.14 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
 BCAP31
 B-cell receptor-associated protein 31
chr9_-_124989804 0.14 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr1_+_167599330 0.14 ENST00000367854.3
ENST00000361496.3
 RCSD1
 RCSD domain containing 1
chr15_+_90544532 0.14 ENST00000268154.4
 ZNF710
 zinc finger protein 710
chrX_-_24665208 0.14 ENST00000356768.4
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr19_-_54676884 0.14 ENST00000376591.4
 TMC4
 transmembrane channel-like 4
chr11_-_74442430 0.13 ENST00000376332.3
 CHRDL2
 chordin-like 2
chr13_-_108518986 0.13 ENST00000375915.2
 FAM155A
 family with sequence similarity 155, member A
chr7_-_121944491 0.13 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
 FEZF1
 FEZ family zinc finger 1
chr4_+_84457250 0.13 ENST00000395226.2
 AGPAT9
 1-acylglycerol-3-phosphate O-acyltransferase 9
chr5_-_41510656 0.13 ENST00000377801.3
 PLCXD3
 phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_+_113376157 0.13 ENST00000228928.7
 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
chr4_+_84457529 0.13 ENST00000264409.4
 AGPAT9
 1-acylglycerol-3-phosphate O-acyltransferase 9
chr7_+_116660246 0.13 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
 ST7
 suppression of tumorigenicity 7
chr7_+_20370746 0.13 ENST00000222573.4
 ITGB8
 integrin, beta 8
chr17_-_46724186 0.13 ENST00000433510.2
 RP11-357H14.17
 RP11-357H14.17
chr6_-_56507586 0.13 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
 DST
 dystonin
chr9_+_12693336 0.13 ENST00000381137.2
ENST00000388918.5
 TYRP1
 tyrosinase-related protein 1
chr10_+_75670862 0.13 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
 PLAU
 plasminogen activator, urokinase
chr3_-_124839648 0.12 ENST00000430155.2
 SLC12A8
 solute carrier family 12, member 8
chr17_+_7533439 0.12 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
 SHBG
 sex hormone-binding globulin
chr12_-_71031185 0.12 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr17_+_7387677 0.12 ENST00000322644.6
 POLR2A
 polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr4_-_80994619 0.12 ENST00000404191.1
 ANTXR2
 anthrax toxin receptor 2
chrX_+_17653413 0.12 ENST00000398097.3
 NHS
 Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr20_-_55100981 0.12 ENST00000243913.4
 GCNT7
 glucosaminyl (N-acetyl) transferase family member 7
chr16_+_66914264 0.12 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
 PDP2
 pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_+_111718036 0.12 ENST00000455401.2
 TAGLN3
 transgelin 3
chrX_+_105969893 0.12 ENST00000255499.2
 RNF128
 ring finger protein 128, E3 ubiquitin protein ligase
chr6_-_47009996 0.12 ENST00000371243.2
 GPR110
 G protein-coupled receptor 110
chr3_-_48229846 0.11 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
 CDC25A
 cell division cycle 25A
chr10_+_96698406 0.11 ENST00000260682.6
 CYP2C9
 cytochrome P450, family 2, subfamily C, polypeptide 9
chr14_+_23305760 0.11 ENST00000311852.6
 MMP14
 matrix metallopeptidase 14 (membrane-inserted)
chr1_-_177134024 0.11 ENST00000367654.3
 ASTN1
 astrotactin 1
chr20_-_62284766 0.11 ENST00000370053.1
 STMN3
 stathmin-like 3
chr4_-_40517984 0.11 ENST00000381795.6
 RBM47
 RNA binding motif protein 47
chr6_-_116381918 0.11 ENST00000606080.1
 FRK
 fyn-related kinase
chr4_+_155484155 0.11 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr3_+_189507523 0.11 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
 TP63
 tumor protein p63
chr4_+_159443024 0.11 ENST00000448688.2
 RXFP1
 relaxin/insulin-like family peptide receptor 1
chr5_-_141257954 0.11 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
 PCDH1
 protocadherin 1
chr8_+_128748466 0.11 ENST00000524013.1
ENST00000520751.1
 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
chr19_-_43702231 0.11 ENST00000597374.1
ENST00000599371.1
 PSG4
 pregnancy specific beta-1-glycoprotein 4
chr14_+_93118813 0.11 ENST00000556418.1
 RIN3
 Ras and Rab interactor 3
chr14_+_22984601 0.11 ENST00000390509.1
 TRAJ28
 T cell receptor alpha joining 28
chr20_-_23066953 0.11 ENST00000246006.4
 CD93
 CD93 molecule
chr19_-_4338838 0.10 ENST00000594605.1
 STAP2
 signal transducing adaptor family member 2
chr9_-_34372830 0.10 ENST00000379142.3
 KIAA1161
 KIAA1161
chrX_+_135730373 0.10 ENST00000370628.2
 CD40LG
 CD40 ligand
chr5_-_41510725 0.10 ENST00000328457.3
 PLCXD3
 phosphatidylinositol-specific phospholipase C, X domain containing 3
chrX_+_135730297 0.10 ENST00000370629.2
 CD40LG
 CD40 ligand
chr11_+_6226782 0.10 ENST00000316375.2
 C11orf42
 chromosome 11 open reading frame 42
chr1_+_117544366 0.10 ENST00000256652.4
ENST00000369470.1
 CD101
 CD101 molecule
chr7_-_100881109 0.10 ENST00000308344.5
 CLDN15
 claudin 15
chr7_+_20370300 0.10 ENST00000537992.1
 ITGB8
 integrin, beta 8
chr1_+_172389821 0.10 ENST00000367727.4
 C1orf105
 chromosome 1 open reading frame 105
chr10_-_14050522 0.10 ENST00000342409.2
 FRMD4A
 FERM domain containing 4A
chr1_-_11024258 0.10 ENST00000418570.2
 C1orf127
 chromosome 1 open reading frame 127
chr8_+_21916680 0.10 ENST00000358242.3
ENST00000415253.1
 DMTN
 dematin actin binding protein
chr11_+_55594695 0.10 ENST00000378397.1
 OR5L2
 olfactory receptor, family 5, subfamily L, member 2
chr18_-_28742813 0.10 ENST00000257197.3
ENST00000257198.5
 DSC1
 desmocollin 1
chr17_-_38938786 0.10 ENST00000301656.3
 KRT27
 keratin 27
chr3_+_109128837 0.10 ENST00000497996.1
 RP11-702L6.4
 RP11-702L6.4
chr13_-_72441315 0.10 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
 DACH1
 dachshund homolog 1 (Drosophila)
chr15_-_68498376 0.10 ENST00000540479.1
ENST00000395465.3
 CALML4
 calmodulin-like 4
chr2_+_90108504 0.10 ENST00000390271.2
 IGKV6D-41
 immunoglobulin kappa variable 6D-41 (non-functional)
chr1_+_214161854 0.10 ENST00000435016.1
 PROX1
 prospero homeobox 1
chr5_-_24645078 0.10 ENST00000264463.4
 CDH10
 cadherin 10, type 2 (T2-cadherin)
chr1_-_177133818 0.09 ENST00000424564.2
ENST00000361833.2
 ASTN1
 astrotactin 1
chr11_+_65554493 0.09 ENST00000335987.3
 OVOL1
 ovo-like zinc finger 1
chr9_-_117568365 0.09 ENST00000374045.4
 TNFSF15
 tumor necrosis factor (ligand) superfamily, member 15
chr8_+_21916710 0.09 ENST00000523266.1
ENST00000519907.1
 DMTN
 dematin actin binding protein
chrX_-_19002696 0.09 ENST00000379942.4
 PHKA2
 phosphorylase kinase, alpha 2 (liver)
chr1_+_172422026 0.09 ENST00000367725.4
 C1orf105
 chromosome 1 open reading frame 105
chr1_-_205391178 0.09 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
 LEMD1
 LEM domain containing 1
chr6_+_44194762 0.09 ENST00000371708.1
 SLC29A1
 solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_-_150884332 0.09 ENST00000275838.1
ENST00000422024.1
ENST00000434669.1
 ASB10
 ankyrin repeat and SOCS box containing 10
chr14_+_60975644 0.09 ENST00000327720.5
 SIX6
 SIX homeobox 6
chr10_+_71389983 0.09 ENST00000373279.4
 C10orf35
 chromosome 10 open reading frame 35
chrX_-_24665353 0.09 ENST00000379144.2
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr8_+_99956759 0.09 ENST00000522510.1
ENST00000457907.2
 OSR2
 odd-skipped related transciption factor 2
chr12_+_175930 0.09 ENST00000538872.1
ENST00000326261.4
 IQSEC3
 IQ motif and Sec7 domain 3
chr2_+_220462560 0.09 ENST00000456909.1
ENST00000295641.10
 STK11IP
 serine/threonine kinase 11 interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0098582 innate vocalization behavior(GO:0098582)
0.3 1.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 1.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 1.2 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.4 GO:0070668 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.8 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.0 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.3 GO:0072192 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.3 GO:0035627 ceramide transport(GO:0035627)
0.1 0.2 GO:0009946 proximal/distal axis specification(GO:0009946)
0.1 0.2 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0098905 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.2 GO:2000974 inhibition of neuroepithelial cell differentiation(GO:0002085) trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.2 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.0 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 1.1 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:0061589 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.3 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 1.7 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.0 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.0 GO:0031960 response to corticosteroid(GO:0031960)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.0 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.0 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0010820 regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.0 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0035054 septum secundum development(GO:0003285) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:2000777 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.9 GO:0045179 apical cortex(GO:0045179)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.6 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 1.0 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions