Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
FOSL1 Links Ensembl NCBI GeneCards UniProt	ENSG00000175592.4	FOSL1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOSL1	hg19_v2_chr11_-_65667884_65667895	0.47	2.4e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr18_+_21452964	9.09	ENST00000587184.1	LAMA3	laminin, alpha 3
chr18_+_21452804	8.86	ENST00000269217.6	LAMA3	laminin, alpha 3
chr3_-_151034734	6.56	ENST00000260843.4	GPR87	G protein-coupled receptor 87
chr1_+_183155373	6.05	ENST00000493293.1 ENST00000264144.4	LAMC2	laminin, gamma 2
chr1_+_153003671	4.43	ENST00000307098.4	SPRR1B	small proline-rich protein 1B
chr18_+_61554932	4.25	ENST00000299502.4 ENST00000457692.1 ENST00000413956.1	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr19_-_36004543	4.15	ENST00000339686.3 ENST00000447113.2 ENST00000440396.1	DMKN	dermokine
chr19_-_35992780	4.05	ENST00000593342.1 ENST00000601650.1 ENST00000408915.2	DMKN	dermokine
chr11_+_394196	3.84	ENST00000331563.2 ENST00000531857.1	PKP3	plakophilin 3
chr17_-_39769005	3.81	ENST00000301653.4 ENST00000593067.1	KRT16	keratin 16
chr19_-_51523412	3.66	ENST00000391805.1 ENST00000599077.1	KLK10	kallikrein-related peptidase 10
chr15_+_40531243	3.58	ENST00000558055.1 ENST00000455577.2	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr19_-_51523275	3.46	ENST00000309958.3	KLK10	kallikrein-related peptidase 10
chr15_+_40531621	3.43	ENST00000560346.1	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_35220613	3.06	ENST00000338513.1	GJB5	gap junction protein, beta 5, 31.1kDa
chr20_+_44637526	2.98	ENST00000372330.3	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr11_-_108408895	2.96	ENST00000443411.1 ENST00000533052.1	EXPH5	exophilin 5
chr1_+_152956549	2.95	ENST00000307122.2	SPRR1A	small proline-rich protein 1A
chr14_-_94854926	2.91	ENST00000402629.1 ENST00000556091.1 ENST00000554720.1	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr2_+_47596287	2.89	ENST00000263735.4	EPCAM	epithelial cell adhesion molecule
chr6_+_47666275	2.83	ENST00000327753.3 ENST00000283303.2	GPR115	G protein-coupled receptor 115
chr15_+_41136586	2.77	ENST00000431806.1	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr18_+_61442629	2.71	ENST00000398019.2 ENST00000540675.1	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_102668879	2.68	ENST00000315274.6	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr15_+_40532058	2.64	ENST00000260404.4	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr6_+_125540951	2.57	ENST00000524679.1	TPD52L1	tumor protein D52-like 1
chr7_+_73245193	2.55	ENST00000340958.2	CLDN4	claudin 4
chr5_+_147582387	2.33	ENST00000325630.2	SPINK6	serine peptidase inhibitor, Kazal type 6
chr8_+_120220561	2.30	ENST00000276681.6	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_+_220492373	2.06	ENST00000317151.3	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr4_-_36246060	2.02	ENST00000303965.4	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_28520447	1.97	ENST00000539896.1	PTAFR	platelet-activating factor receptor
chr11_+_10476851	1.90	ENST00000396553.2	AMPD3	adenosine monophosphate deaminase 3
chr10_+_24755416	1.89	ENST00000396446.1 ENST00000396445.1 ENST00000376451.2	KIAA1217	KIAA1217
chr9_+_35673853	1.88	ENST00000378357.4	CA9	carbonic anhydrase IX
chr16_+_57662138	1.84	ENST00000562414.1 ENST00000561969.1 ENST00000562631.1 ENST00000563445.1 ENST00000565338.1 ENST00000567702.1	GPR56	G protein-coupled receptor 56
chr16_+_30751953	1.84	ENST00000483578.1	RP11-2C24.4	RP11-2C24.4
chr5_+_145317356	1.80	ENST00000511217.1	SH3RF2	SH3 domain containing ring finger 2
chr11_+_12308447	1.79	ENST00000256186.2	MICALCL	MICAL C-terminal like
chr1_+_152881014	1.76	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr6_-_138428613	1.75	ENST00000421351.3	PERP	PERP, TP53 apoptosis effector
chr17_-_8021710	1.74	ENST00000380149.1 ENST00000448843.2	ALOXE3	arachidonate lipoxygenase 3
chr1_-_160990886	1.73	ENST00000537746.1	F11R	F11 receptor
chr4_+_84457250	1.69	ENST00000395226.2	AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr10_-_6019984	1.68	ENST00000525219.2	IL15RA	interleukin 15 receptor, alpha
chr1_-_28520384	1.68	ENST00000305392.3	PTAFR	platelet-activating factor receptor
chr1_-_209824643	1.65	ENST00000391911.1 ENST00000415782.1	LAMB3	laminin, beta 3
chr18_-_74207146	1.65	ENST00000443185.2	ZNF516	zinc finger protein 516
chr4_+_84457529	1.65	ENST00000264409.4	AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_+_57662419	1.65	ENST00000388812.4 ENST00000538815.1 ENST00000456916.1 ENST00000567154.1 ENST00000388813.5 ENST00000562558.1 ENST00000566271.2	GPR56	G protein-coupled receptor 56
chr1_+_62417957	1.63	ENST00000307297.7 ENST00000543708.1	INADL	InaD-like (Drosophila)
chr15_+_41136216	1.59	ENST00000562057.1 ENST00000344051.4	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr13_+_78109804	1.58	ENST00000535157.1	SCEL	sciellin
chr10_-_6019552	1.57	ENST00000379977.3 ENST00000397251.3 ENST00000397248.2	IL15RA	interleukin 15 receptor, alpha
chr13_+_78109884	1.56	ENST00000377246.3 ENST00000349847.3	SCEL	sciellin
chr5_+_35856951	1.52	ENST00000303115.3 ENST00000343305.4 ENST00000506850.1 ENST00000511982.1	IL7R	interleukin 7 receptor
chr2_+_113875466	1.51	ENST00000361779.3 ENST00000259206.5 ENST00000354115.2	IL1RN	interleukin 1 receptor antagonist
chr18_+_55888767	1.49	ENST00000431212.2 ENST00000586268.1 ENST00000587190.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr12_-_53343602	1.49	ENST00000546897.1 ENST00000552551.1	KRT8	keratin 8
chr6_+_106546808	1.45	ENST00000369089.3	PRDM1	PR domain containing 1, with ZNF domain
chr6_+_138188551	1.44	ENST00000237289.4 ENST00000433680.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chrX_-_33229636	1.43	ENST00000357033.4	DMD	dystrophin
chr3_-_98241358	1.39	ENST00000503004.1 ENST00000506575.1 ENST00000513452.1 ENST00000515620.1	CLDND1	claudin domain containing 1
chr14_+_96722539	1.37	ENST00000553356.1	BDKRB1	bradykinin receptor B1
chr22_+_45072925	1.36	ENST00000006251.7	PRR5	proline rich 5 (renal)
chr12_+_56473628	1.35	ENST00000549282.1 ENST00000549061.1 ENST00000267101.3	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr22_+_45072958	1.35	ENST00000403581.1	PRR5	proline rich 5 (renal)
chr5_-_1882858	1.34	ENST00000511126.1 ENST00000231357.2	IRX4	iroquois homeobox 4
chr9_-_139948487	1.34	ENST00000355097.2	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr17_-_39780819	1.34	ENST00000311208.8	KRT17	keratin 17
chr9_-_124991124	1.32	ENST00000394319.4 ENST00000340587.3	LHX6	LIM homeobox 6
chr6_+_41604747	1.31	ENST00000419164.1 ENST00000373051.2	MDFI	MyoD family inhibitor
chr8_+_24771265	1.30	ENST00000518131.1 ENST00000437366.2	NEFM	neurofilament, medium polypeptide
chr1_-_153029980	1.29	ENST00000392653.2	SPRR2A	small proline-rich protein 2A
chr2_+_102618428	1.28	ENST00000457817.1	IL1R2	interleukin 1 receptor, type II
chr3_+_124223586	1.27	ENST00000393496.1	KALRN	kalirin, RhoGEF kinase
chr16_+_50300427	1.27	ENST00000394697.2 ENST00000566433.2 ENST00000538642.1	ADCY7	adenylate cyclase 7
chr1_-_153521597	1.25	ENST00000368712.1	S100A3	S100 calcium binding protein A3
chr1_-_153013588	1.24	ENST00000360379.3	SPRR2D	small proline-rich protein 2D
chr17_+_55162453	1.22	ENST00000575322.1 ENST00000337714.3 ENST00000314126.3	AKAP1	A kinase (PRKA) anchor protein 1
chr6_+_47624172	1.21	ENST00000507065.1 ENST00000296862.1	GPR111	G protein-coupled receptor 111
chr5_-_134914673	1.21	ENST00000512158.1	CXCL14	chemokine (C-X-C motif) ligand 14
chr9_-_23826298	1.21	ENST00000380117.1	ELAVL2	ELAV like neuron-specific RNA binding protein 2
chr12_-_95009837	1.19	ENST00000551457.1	TMCC3	transmembrane and coiled-coil domain family 3
chr1_-_153521714	1.16	ENST00000368713.3	S100A3	S100 calcium binding protein A3
chr14_-_23624511	1.16	ENST00000529705.2	SLC7A8	solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr17_-_39743139	1.16	ENST00000167586.6	KRT14	keratin 14
chr15_+_89182178	1.15	ENST00000559876.1	ISG20	interferon stimulated exonuclease gene 20kDa
chr14_+_96722152	1.13	ENST00000216629.6	BDKRB1	bradykinin receptor B1
chr15_+_89181974	1.12	ENST00000306072.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr17_+_30771279	1.10	ENST00000261712.3 ENST00000578213.1 ENST00000457654.2 ENST00000579451.1	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr15_-_44486632	1.10	ENST00000484674.1	FRMD5	FERM domain containing 5
chr19_+_39279838	1.09	ENST00000314980.4	LGALS7B	lectin, galactoside-binding, soluble, 7B
chr1_+_24646002	1.06	ENST00000356046.2	GRHL3	grainyhead-like 3 (Drosophila)
chr19_-_36019123	1.04	ENST00000588674.1 ENST00000452271.2 ENST00000518157.1	SBSN	suprabasin
chr6_+_151042224	1.04	ENST00000358517.2	PLEKHG1	pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr5_+_135394840	1.03	ENST00000503087.1	TGFBI	transforming growth factor, beta-induced, 68kDa
chr5_+_147582348	1.03	ENST00000514389.1	SPINK6	serine peptidase inhibitor, Kazal type 6
chr1_+_24645807	1.03	ENST00000361548.4	GRHL3	grainyhead-like 3 (Drosophila)
chr11_+_128563652	1.02	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr1_+_24645865	1.02	ENST00000342072.4	GRHL3	grainyhead-like 3 (Drosophila)
chr19_+_7953384	1.02	ENST00000306708.6	LRRC8E	leucine rich repeat containing 8 family, member E
chr12_+_56732658	0.99	ENST00000228534.4	IL23A	interleukin 23, alpha subunit p19
chr16_-_2908155	0.96	ENST00000571228.1 ENST00000161006.3	PRSS22	protease, serine, 22
chr4_+_76481258	0.91	ENST00000311623.4 ENST00000435974.2	C4orf26	chromosome 4 open reading frame 26
chr1_-_153066998	0.90	ENST00000368750.3	SPRR2E	small proline-rich protein 2E
chr15_+_89182156	0.89	ENST00000379224.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr17_-_18908040	0.89	ENST00000388995.6	FAM83G	family with sequence similarity 83, member G
chr17_-_39942940	0.89	ENST00000310706.5 ENST00000393931.3 ENST00000424457.1 ENST00000591690.1	JUP	junction plakoglobin
chr11_+_128563948	0.88	ENST00000534087.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr1_-_6662919	0.87	ENST00000377658.4 ENST00000377663.3	KLHL21	kelch-like family member 21
chr12_-_95510743	0.85	ENST00000551521.1	FGD6	FYVE, RhoGEF and PH domain containing 6
chr17_+_73717551	0.79	ENST00000450894.3	ITGB4	integrin, beta 4
chr2_+_86668464	0.79	ENST00000409064.1	KDM3A	lysine (K)-specific demethylase 3A
chr17_+_73717407	0.78	ENST00000579662.1	ITGB4	integrin, beta 4
chr10_-_6019455	0.77	ENST00000530685.1 ENST00000397255.3 ENST00000379971.1 ENST00000528354.1 ENST00000397250.2 ENST00000429135.2	IL15RA	interleukin 15 receptor, alpha
chr18_+_28956740	0.77	ENST00000308128.4 ENST00000359747.4	DSG4	desmoglein 4
chr17_+_21191341	0.76	ENST00000526076.2 ENST00000361818.5 ENST00000316920.6	MAP2K3	mitogen-activated protein kinase kinase 3
chr11_-_75201791	0.75	ENST00000529721.1	GDPD5	glycerophosphodiester phosphodiesterase domain containing 5
chr4_-_123542224	0.75	ENST00000264497.3	IL21	interleukin 21
chr3_+_112930387	0.74	ENST00000485230.1	BOC	BOC cell adhesion associated, oncogene regulated
chr6_-_44233361	0.74	ENST00000275015.5	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr1_-_95007193	0.74	ENST00000370207.4 ENST00000334047.7	F3	coagulation factor III (thromboplastin, tissue factor)
chr7_+_48128194	0.72	ENST00000416681.1 ENST00000331803.4 ENST00000432131.1	UPP1	uridine phosphorylase 1
chr7_+_48128316	0.72	ENST00000341253.4	UPP1	uridine phosphorylase 1
chr17_-_27503770	0.70	ENST00000533112.1	MYO18A	myosin XVIIIA
chr17_+_74381343	0.70	ENST00000392496.3	SPHK1	sphingosine kinase 1
chr1_-_43751230	0.70	ENST00000523677.1	C1orf210	chromosome 1 open reading frame 210
chr2_-_166651191	0.69	ENST00000392701.3	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chrX_-_154563889	0.69	ENST00000369449.2 ENST00000321926.4	CLIC2	chloride intracellular channel 2
chr3_-_122512619	0.69	ENST00000383659.1 ENST00000306103.2	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr1_+_27189631	0.67	ENST00000339276.4	SFN	stratifin
chr2_-_165697920	0.65	ENST00000342193.4 ENST00000375458.2	COBLL1	cordon-bleu WH2 repeat protein-like 1
chr3_-_98241760	0.64	ENST00000507874.1 ENST00000502299.1 ENST00000508659.1 ENST00000510545.1 ENST00000511667.1 ENST00000394185.2 ENST00000394181.2 ENST00000508902.1 ENST00000341181.6 ENST00000437922.1 ENST00000394180.2	CLDND1	claudin domain containing 1
chr6_+_106534192	0.64	ENST00000369091.2 ENST00000369096.4	PRDM1	PR domain containing 1, with ZNF domain
chr18_-_28742813	0.63	ENST00000257197.3 ENST00000257198.5	DSC1	desmocollin 1
chr1_-_155947951	0.62	ENST00000313695.7 ENST00000497907.1	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr5_-_140013275	0.62	ENST00000512545.1 ENST00000302014.6 ENST00000401743.2	CD14	CD14 molecule
chr12_-_8218997	0.61	ENST00000307637.4	C3AR1	complement component 3a receptor 1
chr9_+_124329336	0.60	ENST00000394340.3 ENST00000436835.1 ENST00000259371.2	DAB2IP	DAB2 interacting protein
chr10_+_104155450	0.60	ENST00000471698.1 ENST00000189444.6	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr14_+_71108460	0.60	ENST00000256367.2	TTC9	tetratricopeptide repeat domain 9
chr11_+_34643600	0.59	ENST00000530286.1 ENST00000533754.1	EHF	ets homologous factor
chr11_+_706113	0.58	ENST00000318562.8 ENST00000533256.1 ENST00000534755.1	EPS8L2	EPS8-like 2
chr8_-_143851203	0.58	ENST00000521396.1 ENST00000317543.7	LYNX1	Ly6/neurotoxin 1
chr1_+_22333943	0.58	ENST00000400271.2	CELA3A	chymotrypsin-like elastase family, member 3A
chr17_+_73717516	0.57	ENST00000200181.3 ENST00000339591.3	ITGB4	integrin, beta 4
chr17_-_43502987	0.57	ENST00000376922.2	ARHGAP27	Rho GTPase activating protein 27
chr20_+_48909240	0.56	ENST00000371639.3	RP11-290F20.1	RP11-290F20.1
chr19_-_35981358	0.56	ENST00000484218.2 ENST00000338897.3	KRTDAP	keratinocyte differentiation-associated protein
chr5_-_78809950	0.56	ENST00000334082.6	HOMER1	homer homolog 1 (Drosophila)
chr16_-_72206034	0.53	ENST00000537465.1 ENST00000237353.10	PMFBP1	polyamine modulated factor 1 binding protein 1
chr13_-_103719196	0.53	ENST00000245312.3	SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr10_+_134901388	0.53	ENST00000392607.3	GPR123	G protein-coupled receptor 123
chr11_+_35198118	0.52	ENST00000525211.1 ENST00000526000.1 ENST00000279452.6 ENST00000527889.1	CD44	CD44 molecule (Indian blood group)
chr11_-_128894053	0.52	ENST00000392657.3	ARHGAP32	Rho GTPase activating protein 32
chr17_-_9694614	0.51	ENST00000330255.5 ENST00000571134.1	DHRS7C	dehydrogenase/reductase (SDR family) member 7C
chr5_-_54281491	0.50	ENST00000381405.4	ESM1	endothelial cell-specific molecule 1
chr1_+_36621697	0.50	ENST00000373150.4 ENST00000373151.2	MAP7D1	MAP7 domain containing 1
chr13_-_36429763	0.49	ENST00000379893.1	DCLK1	doublecortin-like kinase 1
chr7_+_55177416	0.49	ENST00000450046.1 ENST00000454757.2	EGFR	epidermal growth factor receptor
chr19_-_55881741	0.48	ENST00000264563.2 ENST00000590625.1 ENST00000585513.1	IL11	interleukin 11
chr3_-_191000172	0.48	ENST00000427544.2	UTS2B	urotensin 2B
chr21_-_36421535	0.48	ENST00000416754.1 ENST00000437180.1 ENST00000455571.1	RUNX1	runt-related transcription factor 1
chr12_-_53625958	0.47	ENST00000327550.3 ENST00000546717.1 ENST00000425354.2 ENST00000394426.1	RARG	retinoic acid receptor, gamma
chr12_+_9142131	0.47	ENST00000356986.3 ENST00000266551.4	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr10_+_49892904	0.46	ENST00000360890.2	WDFY4	WDFY family member 4
chrX_+_65382433	0.46	ENST00000374727.3	HEPH	hephaestin
chr17_+_74261277	0.45	ENST00000327490.6	UBALD2	UBA-like domain containing 2
chr11_+_35198243	0.44	ENST00000528455.1	CD44	CD44 molecule (Indian blood group)
chr20_-_62129163	0.44	ENST00000298049.7	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr2_-_18770812	0.43	ENST00000359846.2 ENST00000304081.4 ENST00000600945.1 ENST00000532967.1 ENST00000444297.2	NT5C1B NT5C1B-RDH14	5'-nucleotidase, cytosolic IB NT5C1B-RDH14 readthrough
chr6_+_31082603	0.43	ENST00000259881.9	PSORS1C1	psoriasis susceptibility 1 candidate 1
chr6_+_32121218	0.43	ENST00000414204.1 ENST00000361568.2 ENST00000395523.1	PPT2	palmitoyl-protein thioesterase 2
chr19_-_44285401	0.43	ENST00000262888.3	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_+_706219	0.42	ENST00000533500.1	EPS8L2	EPS8-like 2
chr11_-_2924970	0.42	ENST00000533594.1	SLC22A18AS	solute carrier family 22 (organic cation transporter), member 18 antisense
chr7_+_148395959	0.42	ENST00000325222.4	CUL1	cullin 1
chr11_-_47207390	0.42	ENST00000539589.1 ENST00000528462.1	PACSIN3	protein kinase C and casein kinase substrate in neurons 3
chr19_+_17865011	0.41	ENST00000596462.1 ENST00000596865.1 ENST00000598960.1 ENST00000539407.1	FCHO1	FCH domain only 1
chr15_+_98503922	0.41	ENST00000268042.6	ARRDC4	arrestin domain containing 4
chr21_-_36421626	0.40	ENST00000300305.3	RUNX1	runt-related transcription factor 1
chr18_-_53253323	0.40	ENST00000540999.1 ENST00000563888.2	TCF4	transcription factor 4
chr1_-_100598444	0.39	ENST00000535161.1 ENST00000287482.5	SASS6	spindle assembly 6 homolog (C. elegans)
chr19_+_35645618	0.39	ENST00000392218.2 ENST00000543307.1 ENST00000392219.2 ENST00000541435.2 ENST00000590686.1 ENST00000342879.3 ENST00000588699.1	FXYD5	FXYD domain containing ion transport regulator 5
chr17_+_35851570	0.39	ENST00000394386.1	DUSP14	dual specificity phosphatase 14
chr17_-_45928521	0.38	ENST00000536300.1	SP6	Sp6 transcription factor
chrX_-_20074895	0.38	ENST00000543767.1	MAP7D2	MAP7 domain containing 2
chr5_-_137071756	0.37	ENST00000394937.3 ENST00000309755.4	KLHL3	kelch-like family member 3
chr5_+_150020214	0.37	ENST00000307662.4	SYNPO	synaptopodin
chr22_-_32860427	0.36	ENST00000534972.1 ENST00000397450.1 ENST00000397452.1	BPIFC	BPI fold containing family C
chr16_+_81678957	0.36	ENST00000398040.4	CMIP	c-Maf inducing protein
chr14_+_103800513	0.36	ENST00000560338.1 ENST00000560763.1 ENST00000558316.1 ENST00000558265.1	EIF5	eukaryotic translation initiation factor 5
chr12_+_110719032	0.36	ENST00000395494.2	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr18_-_53253112	0.35	ENST00000568673.1 ENST00000562847.1 ENST00000568147.1	TCF4	transcription factor 4
chr12_-_323689	0.35	ENST00000428720.1	SLC6A12	solute carrier family 6 (neurotransmitter transporter), member 12
chr12_+_110718921	0.35	ENST00000308664.6	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr11_+_20620946	0.35	ENST00000525748.1	SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 5
chr16_+_71560154	0.35	ENST00000539698.3	CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr17_-_29641104	0.34	ENST00000577894.1 ENST00000330927.4	EVI2B	ecotropic viral integration site 2B

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.2	GO:1903575	cornified envelope assembly(GO:1903575)
1.2	3.7	GO:1904300	positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
1.0	28.9	GO:0031581	hemidesmosome assembly(GO:0031581)
0.9	4.7	GO:0002159	desmosome assembly(GO:0002159)
0.8	3.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.7	2.7	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.6	3.2	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.6	1.8	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5	2.9	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.5	1.4	GO:0071947	B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.4	1.3	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.4	2.1	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.4	11.7	GO:0061436	establishment of skin barrier(GO:0061436)
0.4	1.4	GO:0006218	uridine catabolic process(GO:0006218)
0.3	0.3	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.3	3.0	GO:2001268	positive regulation of keratinocyte migration(GO:0051549) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.3	1.3	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3	1.9	GO:0006196	AMP catabolic process(GO:0006196)
0.3	6.6	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3	1.5	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3	1.7	GO:0002934	desmosome organization(GO:0002934)
0.3	1.3	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2	0.7	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2	2.9	GO:0038203	TORC2 signaling(GO:0038203)
0.2	0.7	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.2	0.7	GO:1903028	positive regulation of opsonization(GO:1903028)
0.2	0.7	GO:0046521	sphingoid catabolic process(GO:0046521)
0.2	4.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	0.6	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2	0.6	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.2	0.6	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2	0.6	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.2	0.6	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	1.3	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.2	2.3	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	0.7	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.2	1.2	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2	1.0	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2	1.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2	0.8	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.2	0.6	GO:0071725	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2	0.3	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.6	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.1	2.8	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.4	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	1.0	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	16.1	GO:0070268	cornification(GO:0070268)
0.1	1.4	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	1.5	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	3.9	GO:0042730	fibrinolysis(GO:0042730)
0.1	0.6	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.1	0.5	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1	0.6	GO:0043553	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1	0.5	GO:0072156	distal tubule morphogenesis(GO:0072156)
0.1	0.3	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1	1.3	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	1.7	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.7	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1	0.5	GO:0070384	Harderian gland development(GO:0070384)
0.1	0.8	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	0.4	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.5	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.1	1.3	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	1.0	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1	0.3	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.6	GO:0071461	cellular response to redox state(GO:0071461)
0.1	0.2	GO:0030264	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1	0.7	GO:0042940	D-amino acid transport(GO:0042940)
0.1	0.5	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1	0.3	GO:0035937	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1	0.2	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1	0.2	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1	0.3	GO:0098886	modification of dendritic spine(GO:0098886)
0.1	0.5	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	2.5	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1	0.7	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.8	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1	0.3	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.1	0.9	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0021633	optic nerve structural organization(GO:0021633)
0.1	1.3	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	1.3	GO:0071361	cellular response to ethanol(GO:0071361)
0.1	1.4	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.2	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1	0.7	GO:0045785	positive regulation of cell adhesion(GO:0045785)
0.0	0.3	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.9	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.0	0.2	GO:1901094	regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0	0.6	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.4	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.0	2.9	GO:0006953	acute-phase response(GO:0006953)
0.0	0.4	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.4	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	1.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	1.2	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	1.2	GO:0015695	organic cation transport(GO:0015695)
0.0	0.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.5	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	1.9	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.7	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:0060516	primary prostatic bud elongation(GO:0060516)
0.0	0.4	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.1	GO:0060720	spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0	0.5	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.5	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.0	0.2	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.0	0.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.2	GO:2000507	cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507)
0.0	0.0	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.0	1.0	GO:0044380	protein localization to cytoskeleton(GO:0044380)
0.0	0.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	1.9	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.6	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0	2.0	GO:0030216	keratinocyte differentiation(GO:0030216)
0.0	0.3	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	5.7	GO:0031098	stress-activated protein kinase signaling cascade(GO:0031098)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.4	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	1.3	GO:0009798	axis specification(GO:0009798)
0.0	0.4	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0	0.3	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.0	0.1	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.0	0.4	GO:0007099	centriole replication(GO:0007099)
0.0	0.2	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0	0.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	19.6	GO:0005610	laminin-5 complex(GO:0005610)
2.0	6.0	GO:0005607	laminin-2 complex(GO:0005607)
0.3	21.2	GO:0001533	cornified envelope(GO:0001533)
0.2	0.6	GO:1990032	parallel fiber(GO:1990032)
0.2	1.7	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	0.5	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.1	0.6	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	1.7	GO:0030057	desmosome(GO:0030057)
0.1	1.4	GO:0016013	syntrophin complex(GO:0016013)
0.1	1.0	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	1.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	3.1	GO:0005922	connexon complex(GO:0005922)
0.1	2.9	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	3.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.9	GO:0005827	polar microtubule(GO:0005827)
0.1	0.3	GO:0097444	spine apparatus(GO:0097444)
0.1	0.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	1.3	GO:0005883	neurofilament(GO:0005883)
0.1	0.4	GO:0098536	deuterosome(GO:0098536)
0.1	1.8	GO:0031528	microvillus membrane(GO:0031528)
0.1	1.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	4.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	0.7	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.3	GO:1990037	Lewy body core(GO:1990037)
0.0	1.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0033565	ESCRT-0 complex(GO:0033565)
0.0	1.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	8.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.4	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.2	GO:0097513	myosin II filament(GO:0097513)
0.0	3.0	GO:0015030	Cajal body(GO:0015030)
0.0	1.0	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	1.0	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.0	3.2	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	2.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.8	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.3	GO:0033010	paranodal junction(GO:0033010)
0.0	0.5	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.5	GO:0044295	axonal growth cone(GO:0044295)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	1.0	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.6	GO:0043198	dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0008859	exoribonuclease II activity(GO:0008859)
0.8	2.5	GO:0004947	bradykinin receptor activity(GO:0004947)
0.5	1.5	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.4	1.7	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.4	10.2	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	1.4	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.3	3.5	GO:0038132	neuregulin binding(GO:0038132)
0.3	1.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	3.8	GO:0030280	structural constituent of epidermis(GO:0030280)
0.3	1.3	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.3	0.8	GO:0047389	glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2	3.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	1.9	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2	0.7	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	0.5	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	2.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.6	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	1.5	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	17.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.6	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.1	0.7	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	10.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	1.9	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	1.6	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.1	0.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.6	GO:1903135	cupric ion binding(GO:1903135)
0.1	1.2	GO:0019534	toxin transporter activity(GO:0019534)
0.1	0.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	0.5	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	2.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.3	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.1	0.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.6	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.4	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	1.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	1.8	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	2.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.2	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.1	0.2	GO:0004370	glycerol kinase activity(GO:0004370)
0.1	0.3	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.7	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.4	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.8	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	1.0	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	2.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	1.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.5	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.8	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	7.2	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	1.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.6	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.2	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.0	0.8	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.4	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	1.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.6	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.4	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.5	GO:0030957	Tat protein binding(GO:0030957)
0.0	1.8	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.2	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0	0.4	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.2	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0	1.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	26.8	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	3.0	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0	1.9	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	4.6	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0	1.9	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.7	GO:0008009	chemokine activity(GO:0008009)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	1.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	1.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0052839	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.7	GO:0043531	ADP binding(GO:0043531)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	4.2	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.3	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	27.8	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.3	2.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	9.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	0.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	3.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	2.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	1.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	2.6	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	3.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	4.4	PID P73PATHWAY	p73 transcription factor network
0.0	4.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.4	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	2.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.8	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.7	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.6	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.4	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	1.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	2.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	32.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	3.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	3.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.5	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	1.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	0.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	0.8	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	3.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.8	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	3.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	2.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	1.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	1.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse