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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for FOXA1

Z-value: 1.02

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Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
FOXA1
ENSG00000129514.4 FOXA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg19_v2_chr14_-_38064198_38064239-0.511.9e-01Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_91572278 1.62 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
 DCN
 decorin
chr9_-_95186739 1.42 ENST00000375550.4
 OMD
 osteomodulin
chr5_+_156712372 0.91 ENST00000541131.1
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr5_-_41510725 0.69 ENST00000328457.3
 PLCXD3
 phosphatidylinositol-specific phospholipase C, X domain containing 3
chr5_-_41510656 0.69 ENST00000377801.3
 PLCXD3
 phosphatidylinositol-specific phospholipase C, X domain containing 3
chr13_-_67802549 0.69 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr18_-_25616519 0.64 ENST00000399380.3
 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
chr17_-_19651668 0.61 ENST00000494157.2
ENST00000225740.6
 ALDH3A1
 aldehyde dehydrogenase 3 family, member A1
chrX_+_9431324 0.60 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X
 transducin (beta)-like 1X-linked
chr6_-_117747015 0.59 ENST00000368508.3
ENST00000368507.3
 ROS1
 c-ros oncogene 1 , receptor tyrosine kinase
chr10_+_124320156 0.58 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
 DMBT1
 deleted in malignant brain tumors 1
chr10_+_124320195 0.57 ENST00000359586.6
 DMBT1
 deleted in malignant brain tumors 1
chr8_+_70404996 0.54 ENST00000402687.4
ENST00000419716.3
 SULF1
 sulfatase 1
chr13_+_76334498 0.52 ENST00000534657.1
 LMO7
 LIM domain 7
chr4_+_55095264 0.49 ENST00000257290.5
 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
chr6_-_87804815 0.49 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide
chr1_+_223101757 0.49 ENST00000284476.6
 DISP1
 dispatched homolog 1 (Drosophila)
chr6_-_56707943 0.47 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
 DST
 dystonin
chr2_-_192711968 0.46 ENST00000304141.4
 SDPR
 serum deprivation response
chr6_+_108977520 0.45 ENST00000540898.1
 FOXO3
 forkhead box O3
chr9_-_20622478 0.42 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr5_-_127674883 0.41 ENST00000507835.1
 FBN2
 fibrillin 2
chr1_-_232651312 0.40 ENST00000262861.4
 SIPA1L2
 signal-induced proliferation-associated 1 like 2
chr2_+_172950227 0.40 ENST00000341900.6
 DLX1
 distal-less homeobox 1
chr9_-_89562104 0.39 ENST00000298743.7
 GAS1
 growth arrest-specific 1
chr3_+_69985734 0.38 ENST00000314557.6
ENST00000394351.3
 MITF
 microphthalmia-associated transcription factor
chr2_-_158345462 0.38 ENST00000439355.1
ENST00000540637.1
 CYTIP
 cytohesin 1 interacting protein
chr13_+_76334795 0.35 ENST00000526202.1
ENST00000465261.2
 LMO7
 LIM domain 7
chr1_+_101361782 0.34 ENST00000357650.4
 SLC30A7
 solute carrier family 30 (zinc transporter), member 7
chr5_+_150157444 0.33 ENST00000526627.1
 SMIM3
 small integral membrane protein 3
chr20_-_45984401 0.33 ENST00000311275.7
 ZMYND8
 zinc finger, MYND-type containing 8
chr6_-_88875654 0.33 ENST00000535130.1
 CNR1
 cannabinoid receptor 1 (brain)
chr5_+_150157860 0.32 ENST00000600109.1
 AC010441.1
 AC010441.1
chr13_+_76334567 0.30 ENST00000321797.8
 LMO7
 LIM domain 7
chr9_-_123239632 0.30 ENST00000416449.1
 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
chrX_+_85969626 0.30 ENST00000484479.1
 DACH2
 dachshund homolog 2 (Drosophila)
chr17_+_79953310 0.30 ENST00000582355.2
 ASPSCR1
 alveolar soft part sarcoma chromosome region, candidate 1
chrX_+_22050546 0.29 ENST00000379374.4
 PHEX
 phosphate regulating endopeptidase homolog, X-linked
chr10_-_90751038 0.28 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr12_-_71551868 0.28 ENST00000247829.3
 TSPAN8
 tetraspanin 8
chr3_+_148545586 0.27 ENST00000282957.4
ENST00000468341.1
 CPB1
 carboxypeptidase B1 (tissue)
chr15_+_96869165 0.27 ENST00000421109.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr1_+_40713573 0.26 ENST00000372766.3
 TMCO2
 transmembrane and coiled-coil domains 2
chr12_-_71551652 0.26 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr8_+_77593448 0.26 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr3_-_145878954 0.25 ENST00000282903.5
ENST00000360060.3
 PLOD2
 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr20_+_31823792 0.25 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
 BPIFA1
 BPI fold containing family A, member 1
chr8_+_77593474 0.25 ENST00000455469.2
ENST00000050961.6
 ZFHX4
 zinc finger homeobox 4
chr12_-_92536433 0.25 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
 C12orf79
 chromosome 12 open reading frame 79
chr1_+_198126093 0.24 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
 NEK7
 NIMA-related kinase 7
chr3_+_141106643 0.24 ENST00000514251.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr3_+_148447887 0.24 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
 AGTR1
 angiotensin II receptor, type 1
chr7_+_134430212 0.24 ENST00000436461.2
 CALD1
 caldesmon 1
chr3_-_71632894 0.23 ENST00000493089.1
 FOXP1
 forkhead box P1
chr2_-_233877912 0.23 ENST00000264051.3
 NGEF
 neuronal guanine nucleotide exchange factor
chr7_+_134576317 0.23 ENST00000424922.1
ENST00000495522.1
 CALD1
 caldesmon 1
chr11_-_9286921 0.23 ENST00000328194.3
 DENND5A
 DENN/MADD domain containing 5A
chr10_+_104535994 0.23 ENST00000369889.4
 WBP1L
 WW domain binding protein 1-like
chr2_+_169757750 0.22 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
 G6PC2
 glucose-6-phosphatase, catalytic, 2
chr11_-_102401469 0.22 ENST00000260227.4
 MMP7
 matrix metallopeptidase 7 (matrilysin, uterine)
chr5_+_102201509 0.22 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr5_+_102201430 0.22 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr1_+_61547405 0.22 ENST00000371189.4
 NFIA
 nuclear factor I/A
chr5_-_137674000 0.21 ENST00000510119.1
ENST00000513970.1
 CDC25C
 cell division cycle 25C
chr3_-_105588231 0.21 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr2_-_182545603 0.20 ENST00000295108.3
 NEUROD1
 neuronal differentiation 1
chr8_+_95908041 0.20 ENST00000396113.1
ENST00000519136.1
 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr1_-_27240455 0.20 ENST00000254227.3
 NR0B2
 nuclear receptor subfamily 0, group B, member 2
chr15_+_75335604 0.20 ENST00000563393.1
 PPCDC
 phosphopantothenoylcysteine decarboxylase
chr5_+_147774275 0.20 ENST00000513826.1
 FBXO38
 F-box protein 38
chr11_+_120973375 0.19 ENST00000264037.2
 TECTA
 tectorin alpha
chr9_+_6413317 0.19 ENST00000276893.5
ENST00000381373.3
 UHRF2
 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
chr18_+_3449330 0.18 ENST00000549253.1
 TGIF1
 TGFB-induced factor homeobox 1
chr2_+_152266604 0.18 ENST00000430328.2
 RIF1
 RAP1 interacting factor homolog (yeast)
chr2_+_88047606 0.18 ENST00000359481.4
 PLGLB2
 plasminogen-like B2
chr20_+_31595406 0.17 ENST00000170150.3
 BPIFB2
 BPI fold containing family B, member 2
chr16_-_4896205 0.17 ENST00000589389.1
 GLYR1
 glyoxylate reductase 1 homolog (Arabidopsis)
chr7_+_134576151 0.17 ENST00000393118.2
 CALD1
 caldesmon 1
chr16_-_87970122 0.16 ENST00000309893.2
 CA5A
 carbonic anhydrase VA, mitochondrial
chr11_+_35684288 0.16 ENST00000299413.5
 TRIM44
 tripartite motif containing 44
chr18_+_72922710 0.15 ENST00000322038.5
 TSHZ1
 teashirt zinc finger homeobox 1
chr1_+_104159999 0.15 ENST00000414303.2
ENST00000423678.1
 AMY2A
 amylase, alpha 2A (pancreatic)
chr12_+_103981044 0.15 ENST00000388887.2
 STAB2
 stabilin 2
chr12_-_56122761 0.15 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
 CD63
 CD63 molecule
chr6_-_111804393 0.14 ENST00000368802.3
ENST00000368805.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr21_-_43735446 0.14 ENST00000398431.2
 TFF3
 trefoil factor 3 (intestinal)
chr16_+_4896659 0.14 ENST00000592120.1
 UBN1
 ubinuclein 1
chr10_-_81320151 0.14 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
 SFTPA2
 surfactant protein A2
chr3_+_69985792 0.14 ENST00000531774.1
 MITF
 microphthalmia-associated transcription factor
chr1_-_177939348 0.14 ENST00000464631.2
 SEC16B
 SEC16 homolog B (S. cerevisiae)
chr6_+_74405501 0.13 ENST00000437994.2
ENST00000422508.2
 CD109
 CD109 molecule
chr5_-_133510456 0.13 ENST00000520417.1
 SKP1
 S-phase kinase-associated protein 1
chr22_+_35462129 0.13 ENST00000404699.2
ENST00000308700.6
 ISX
 intestine-specific homeobox
chr6_+_74405804 0.13 ENST00000287097.5
 CD109
 CD109 molecule
chr2_-_152146385 0.13 ENST00000414946.1
ENST00000243346.5
 NMI
 N-myc (and STAT) interactor
chr12_-_120765565 0.13 ENST00000423423.3
ENST00000308366.4
 PLA2G1B
 phospholipase A2, group IB (pancreas)
chr13_+_50589390 0.13 ENST00000360473.4
ENST00000312942.1
 KCNRG
 potassium channel regulator
chr18_+_66465302 0.13 ENST00000360242.5
ENST00000358653.5
 CCDC102B
 coiled-coil domain containing 102B
chr12_+_121416437 0.13 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
 HNF1A
 HNF1 homeobox A
chr12_-_56123444 0.12 ENST00000546457.1
ENST00000549117.1
 CD63
 CD63 molecule
chr2_-_3521518 0.12 ENST00000382093.5
 ADI1
 acireductone dioxygenase 1
chr11_-_116663127 0.12 ENST00000433069.1
ENST00000542499.1
 APOA5
 apolipoprotein A-V
chr4_+_187187098 0.12 ENST00000403665.2
ENST00000264692.4
 F11
 coagulation factor XI
chrX_-_47863348 0.12 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
 ZNF182
 zinc finger protein 182
chr3_+_108321623 0.11 ENST00000497905.1
ENST00000463306.1
 DZIP3
 DAZ interacting zinc finger protein 3
chr19_+_50380917 0.11 ENST00000535102.2
 TBC1D17
 TBC1 domain family, member 17
chr19_+_50380682 0.11 ENST00000221543.5
 TBC1D17
 TBC1 domain family, member 17
chr21_+_33671160 0.11 ENST00000303645.5
 MRAP
 melanocortin 2 receptor accessory protein
chr18_+_70536215 0.11 ENST00000578967.1
 RP11-676J15.1
 RP11-676J15.1
chr16_-_68034470 0.11 ENST00000412757.2
 DPEP2
 dipeptidase 2
chr17_-_40897043 0.11 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
 EZH1
 enhancer of zeste homolog 1 (Drosophila)
chr19_+_42806250 0.11 ENST00000598490.1
ENST00000341747.3
 PRR19
 proline rich 19
chr1_+_116654376 0.11 ENST00000369500.3
 MAB21L3
 mab-21-like 3 (C. elegans)
chr4_+_170581213 0.11 ENST00000507875.1
 CLCN3
 chloride channel, voltage-sensitive 3
chr8_-_116681221 0.10 ENST00000395715.3
 TRPS1
 trichorhinophalangeal syndrome I
chr3_-_194030493 0.10 ENST00000456816.1
ENST00000414120.1
ENST00000429578.1
 LINC00887
 long intergenic non-protein coding RNA 887
chr10_+_91092241 0.10 ENST00000371811.4
 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
chr14_+_64971292 0.10 ENST00000358738.3
ENST00000394712.2
 ZBTB1
 zinc finger and BTB domain containing 1
chrX_+_135730297 0.10 ENST00000370629.2
 CD40LG
 CD40 ligand
chr11_+_57308979 0.10 ENST00000457912.1
 SMTNL1
 smoothelin-like 1
chr5_+_95998746 0.10 ENST00000508608.1
 CAST
 calpastatin
chr4_-_155533787 0.10 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
 FGG
 fibrinogen gamma chain
chr4_+_165675269 0.10 ENST00000507311.1
 RP11-294O2.2
 RP11-294O2.2
chrX_+_135730373 0.10 ENST00000370628.2
 CD40LG
 CD40 ligand
chr12_+_96588143 0.10 ENST00000228741.3
ENST00000547249.1
 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
chr1_+_61547894 0.09 ENST00000403491.3
 NFIA
 nuclear factor I/A
chr1_-_57431679 0.09 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
 C8B
 complement component 8, beta polypeptide
chr4_+_26321284 0.09 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr7_+_116165754 0.09 ENST00000405348.1
 CAV1
 caveolin 1, caveolae protein, 22kDa
chr2_+_65283506 0.09 ENST00000377990.2
 CEP68
 centrosomal protein 68kDa
chr20_+_44420617 0.09 ENST00000449078.1
ENST00000456939.1
 DNTTIP1
 deoxynucleotidyltransferase, terminal, interacting protein 1
chr1_-_95391315 0.09 ENST00000545882.1
ENST00000415017.1
 CNN3
 calponin 3, acidic
chr11_-_124622134 0.09 ENST00000326621.5
 VSIG2
 V-set and immunoglobulin domain containing 2
chr3_+_137728842 0.09 ENST00000183605.5
 CLDN18
 claudin 18
chr8_+_95907993 0.09 ENST00000523378.1
 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr2_+_65283529 0.09 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
 CEP68
 centrosomal protein 68kDa
chr13_-_31038370 0.08 ENST00000399489.1
ENST00000339872.4
 HMGB1
 high mobility group box 1
chr6_+_84222194 0.08 ENST00000536636.1
 PRSS35
 protease, serine, 35
chr7_-_7782204 0.08 ENST00000418534.2
 AC007161.5
 AC007161.5
chr3_-_71294304 0.08 ENST00000498215.1
 FOXP1
 forkhead box P1
chr10_+_124739911 0.08 ENST00000405485.1
 PSTK
 phosphoseryl-tRNA kinase
chr17_+_36873677 0.08 ENST00000471200.1
 MLLT6
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_179345173 0.08 ENST00000234453.5
 PLEKHA3
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr19_-_15443318 0.08 ENST00000360016.5
 BRD4
 bromodomain containing 4
chr7_+_134832808 0.08 ENST00000275767.3
 TMEM140
 transmembrane protein 140
chr20_+_44420570 0.08 ENST00000372622.3
 DNTTIP1
 deoxynucleotidyltransferase, terminal, interacting protein 1
chr2_-_121223697 0.08 ENST00000593290.1
 FLJ14816
 long intergenic non-protein coding RNA 1101
chr19_-_18902106 0.08 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
 COMP
 cartilage oligomeric matrix protein
chr14_+_64970662 0.08 ENST00000556965.1
ENST00000554015.1
 ZBTB1
 zinc finger and BTB domain containing 1
chr10_+_124739964 0.08 ENST00000406217.2
 PSTK
 phosphoseryl-tRNA kinase
chr2_-_172017343 0.08 ENST00000431350.2
ENST00000360843.3
 TLK1
 tousled-like kinase 1
chr14_-_24911448 0.08 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
 SDR39U1
 short chain dehydrogenase/reductase family 39U, member 1
chrX_+_129473916 0.08 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr13_-_45775162 0.07 ENST00000405872.1
 KCTD4
 potassium channel tetramerization domain containing 4
chr14_-_94789663 0.07 ENST00000557225.1
ENST00000341584.3
 SERPINA6
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_-_90025011 0.07 ENST00000402938.3
 GABRR2
 gamma-aminobutyric acid (GABA) A receptor, rho 2
chr9_-_14910420 0.07 ENST00000380880.3
 FREM1
 FRAS1 related extracellular matrix 1
chr12_-_68647281 0.07 ENST00000328087.4
ENST00000538666.1
 IL22
 interleukin 22
chr6_+_84222220 0.07 ENST00000369700.3
 PRSS35
 protease, serine, 35
chr12_-_772901 0.07 ENST00000305108.4
 NINJ2
 ninjurin 2
chr15_+_71389281 0.07 ENST00000355327.3
 THSD4
 thrombospondin, type I, domain containing 4
chr20_-_43150601 0.07 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
 SERINC3
 serine incorporator 3
chr20_+_306177 0.07 ENST00000544632.1
 SOX12
 SRY (sex determining region Y)-box 12
chr10_+_102891048 0.07 ENST00000467928.2
 TLX1
 T-cell leukemia homeobox 1
chr2_+_204801471 0.07 ENST00000316386.6
ENST00000435193.1
 ICOS
 inducible T-cell co-stimulator
chrX_+_37865804 0.07 ENST00000297875.2
ENST00000357972.5
 SYTL5
 synaptotagmin-like 5
chr1_+_145883868 0.07 ENST00000447947.2
 GPR89C
 G protein-coupled receptor 89C
chr6_-_90024967 0.07 ENST00000602399.1
 GABRR2
 gamma-aminobutyric acid (GABA) A receptor, rho 2
chr1_+_43855560 0.07 ENST00000562955.1
 SZT2
 seizure threshold 2 homolog (mouse)
chr20_-_50179368 0.07 ENST00000609943.1
ENST00000609507.1
 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr8_-_71316021 0.07 ENST00000452400.2
 NCOA2
 nuclear receptor coactivator 2
chr5_+_161495038 0.07 ENST00000393933.4
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr6_-_89927151 0.06 ENST00000454853.2
 GABRR1
 gamma-aminobutyric acid (GABA) A receptor, rho 1
chr1_+_35734562 0.06 ENST00000314607.6
ENST00000373297.2
 ZMYM4
 zinc finger, MYM-type 4
chr1_+_74701062 0.06 ENST00000326637.3
 TNNI3K
 TNNI3 interacting kinase
chr1_+_199996733 0.06 ENST00000236914.3
 NR5A2
 nuclear receptor subfamily 5, group A, member 2
chr10_-_32217717 0.06 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
 ARHGAP12
 Rho GTPase activating protein 12
chr1_-_43855479 0.06 ENST00000290663.6
ENST00000372457.4
 MED8
 mediator complex subunit 8
chr10_-_73848086 0.06 ENST00000536168.1
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_80231466 0.06 ENST00000309881.7
ENST00000534394.1
 CD36
 CD36 molecule (thrombospondin receptor)
chr7_-_99698338 0.06 ENST00000354230.3
ENST00000425308.1
 MCM7
 minichromosome maintenance complex component 7
chr9_+_82187630 0.06 ENST00000265284.6
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_+_28452130 0.06 ENST00000357727.2
 CREB5
 cAMP responsive element binding protein 5
chr6_+_161123270 0.06 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
 PLG
 plasminogen
chr20_+_306221 0.06 ENST00000342665.2
 SOX12
 SRY (sex determining region Y)-box 12
chr9_+_82186872 0.05 ENST00000376544.3
ENST00000376520.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_+_16178317 0.05 ENST00000344824.6
ENST00000538887.1
 TPM4
 tropomyosin 4
chr2_+_150187020 0.05 ENST00000334166.4
 LYPD6
 LY6/PLAUR domain containing 6
chr11_-_26743546 0.05 ENST00000280467.6
ENST00000396005.3
 SLC5A12
 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_+_214161854 0.05 ENST00000435016.1
 PROX1
 prospero homeobox 1
chr16_-_49698136 0.05 ENST00000535559.1
 ZNF423
 zinc finger protein 423
chr2_+_152266392 0.05 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
 RIF1
 RAP1 interacting factor homolog (yeast)
chr2_-_87248975 0.05 ENST00000409310.2
ENST00000355705.3
 PLGLB1
 plasminogen-like B1
chr19_+_44037334 0.05 ENST00000314228.5
 ZNF575
 zinc finger protein 575
chr4_-_186456652 0.05 ENST00000284767.5
ENST00000284770.5
 PDLIM3
 PDZ and LIM domain 3
chr17_+_4613918 0.05 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
 ARRB2
 arrestin, beta 2
chr2_+_103089756 0.05 ENST00000295269.4
 SLC9A4
 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr7_+_106505696 0.05 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr6_-_165989936 0.05 ENST00000354448.4
 PDE10A
 phosphodiesterase 10A
chr1_-_120354079 0.05 ENST00000354219.1
ENST00000369401.4
ENST00000256585.5
 REG4
 regenerating islet-derived family, member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 1.0 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 1.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 0.3 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0030300 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.1 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 1.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0000406 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide