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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for GLIS2

Z-value: 0.75

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Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
GLIS2
ENSG00000126603.4 GLIS2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg19_v2_chr16_+_4364762_4364762,
hg19_v2_chr16_+_4382225_4382225		-0.108.1e-01Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_44637526 0.76 ENST00000372330.3
 MMP9
 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr14_-_105635090 0.76 ENST00000331782.3
ENST00000347004.2
 JAG2
 jagged 2
chr19_-_6720686 0.55 ENST00000245907.6
 C3
 complement component 3
chr5_+_68788594 0.50 ENST00000396442.2
ENST00000380766.2
 OCLN
 occludin
chr1_-_28520447 0.49 ENST00000539896.1
 PTAFR
 platelet-activating factor receptor
chr12_-_51785182 0.45 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
 GALNT6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr7_+_69064300 0.44 ENST00000342771.4
 AUTS2
 autism susceptibility candidate 2
chr16_-_68269971 0.42 ENST00000565858.1
 ESRP2
 epithelial splicing regulatory protein 2
chr5_-_176836577 0.40 ENST00000253496.3
 F12
 coagulation factor XII (Hageman factor)
chr13_-_20767037 0.37 ENST00000382848.4
 GJB2
 gap junction protein, beta 2, 26kDa
chr2_+_220492373 0.36 ENST00000317151.3
 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
chr1_-_186649543 0.36 ENST00000367468.5
 PTGS2
 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr19_-_55652290 0.35 ENST00000589745.1
 TNNT1
 troponin T type 1 (skeletal, slow)
chr1_-_156675535 0.35 ENST00000368221.1
 CRABP2
 cellular retinoic acid binding protein 2
chr19_+_45409011 0.34 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
 APOE
 apolipoprotein E
chr3_-_48470838 0.34 ENST00000358459.4
ENST00000358536.4
 PLXNB1
 plexin B1
chr18_+_11752040 0.33 ENST00000423027.3
 GNAL
 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr19_-_49567124 0.32 ENST00000301411.3
 NTF4
 neurotrophin 4
chr1_-_209824643 0.31 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr1_+_65613217 0.31 ENST00000545314.1
 AK4
 adenylate kinase 4
chr1_-_156675368 0.31 ENST00000368222.3
 CRABP2
 cellular retinoic acid binding protein 2
chr19_+_17858509 0.29 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
 FCHO1
 FCH domain only 1
chr20_+_30640004 0.29 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
 HCK
 hemopoietic cell kinase
chr22_-_39640756 0.27 ENST00000331163.6
 PDGFB
 platelet-derived growth factor beta polypeptide
chr22_+_45072925 0.27 ENST00000006251.7
 PRR5
 proline rich 5 (renal)
chr8_+_98881268 0.27 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
 MATN2
 matrilin 2
chr22_+_45072958 0.27 ENST00000403581.1
 PRR5
 proline rich 5 (renal)
chr14_+_94640633 0.26 ENST00000304338.3
 PPP4R4
 protein phosphatase 4, regulatory subunit 4
chr11_+_64058758 0.25 ENST00000538767.1
 KCNK4
 potassium channel, subfamily K, member 4
chr11_-_72353451 0.24 ENST00000376450.3
 PDE2A
 phosphodiesterase 2A, cGMP-stimulated
chr14_-_92302784 0.24 ENST00000340892.5
ENST00000360594.5
 TC2N
 tandem C2 domains, nuclear
chr17_+_78075361 0.24 ENST00000577106.1
ENST00000390015.3
 GAA
 glucosidase, alpha; acid
chr19_+_49891475 0.23 ENST00000447857.3
 CCDC155
 coiled-coil domain containing 155
chr16_-_29910365 0.23 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
 SEZ6L2
 seizure related 6 homolog (mouse)-like 2
chr19_+_45417504 0.22 ENST00000588750.1
ENST00000588802.1
 APOC1
 apolipoprotein C-I
chr19_+_45417812 0.22 ENST00000592535.1
 APOC1
 apolipoprotein C-I
chr19_+_17858547 0.22 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
 FCHO1
 FCH domain only 1
chr2_+_114737472 0.21 ENST00000420161.1
 AC110769.3
 AC110769.3
chr6_+_33048222 0.21 ENST00000428835.1
 HLA-DPB1
 major histocompatibility complex, class II, DP beta 1
chr11_+_121447469 0.21 ENST00000532694.1
ENST00000534286.1
 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
chr20_+_30639991 0.21 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
 HCK
 hemopoietic cell kinase
chr17_+_47572647 0.21 ENST00000172229.3
 NGFR
 nerve growth factor receptor
chr19_-_50979981 0.20 ENST00000595790.1
ENST00000600100.1
 FAM71E1
 family with sequence similarity 71, member E1
chr14_-_21566731 0.20 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr17_+_48503519 0.20 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
 ACSF2
 acyl-CoA synthetase family member 2
chr19_+_45418067 0.20 ENST00000589078.1
ENST00000586638.1
 APOC1
 apolipoprotein C-I
chr19_+_20959098 0.19 ENST00000360204.5
ENST00000594534.1
 ZNF66
 zinc finger protein 66
chr17_+_48503603 0.19 ENST00000502667.1
 ACSF2
 acyl-CoA synthetase family member 2
chr13_-_114018400 0.19 ENST00000375430.4
ENST00000375431.4
 GRTP1
 growth hormone regulated TBC protein 1
chrX_+_102469997 0.18 ENST00000372695.5
ENST00000372691.3
 BEX4
 brain expressed, X-linked 4
chr17_-_34257771 0.18 ENST00000394529.3
ENST00000293273.6
 RDM1
 RAD52 motif 1
chr19_+_45417921 0.18 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
 APOC1
 apolipoprotein C-I
chr1_-_6550625 0.18 ENST00000377725.1
ENST00000340850.5
 PLEKHG5
 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_+_45349630 0.18 ENST00000252483.5
 PVRL2
 poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr2_+_37571717 0.17 ENST00000338415.3
ENST00000404976.1
 QPCT
 glutaminyl-peptide cyclotransferase
chr3_-_128840604 0.17 ENST00000476465.1
ENST00000315150.5
ENST00000393304.1
ENST00000393308.1
ENST00000393307.1
ENST00000393305.1
 RAB43
 RAB43, member RAS oncogene family
chr1_-_43751230 0.17 ENST00000523677.1
 C1orf210
 chromosome 1 open reading frame 210
chr6_-_2903514 0.16 ENST00000380698.4
 SERPINB9
 serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr22_+_29469100 0.16 ENST00000327813.5
ENST00000407188.1
 KREMEN1
 kringle containing transmembrane protein 1
chr12_+_50017327 0.16 ENST00000261897.1
 PRPF40B
 PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr12_+_50017184 0.16 ENST00000548825.2
 PRPF40B
 PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_-_46405861 0.15 ENST00000322217.5
 MYPOP
 Myb-related transcription factor, partner of profilin
chr19_-_2050852 0.15 ENST00000541165.1
ENST00000591601.1
 MKNK2
 MAP kinase interacting serine/threonine kinase 2
chr17_-_34257731 0.15 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
 RDM1
 RAD52 motif 1
chr17_-_4463856 0.14 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
 GGT6
 gamma-glutamyltransferase 6
chr1_-_23810664 0.14 ENST00000336689.3
ENST00000437606.2
 ASAP3
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr8_+_118533049 0.14 ENST00000522839.1
 MED30
 mediator complex subunit 30
chr11_+_63753883 0.14 ENST00000538426.1
ENST00000543004.1
 OTUB1
 OTU domain, ubiquitin aldehyde binding 1
chr6_-_133119668 0.14 ENST00000275227.4
ENST00000538764.1
 SLC18B1
 solute carrier family 18, subfamily B, member 1
chr12_+_50451462 0.13 ENST00000447966.2
 ASIC1
 acid-sensing (proton-gated) ion channel 1
chr5_-_1524015 0.13 ENST00000283415.3
 LPCAT1
 lysophosphatidylcholine acyltransferase 1
chr11_+_68451943 0.13 ENST00000265643.3
 GAL
 galanin/GMAP prepropeptide
chr10_-_14880566 0.13 ENST00000378442.1
 CDNF
 cerebral dopamine neurotrophic factor
chr19_-_16008880 0.13 ENST00000011989.7
ENST00000221700.6
 CYP4F2
 cytochrome P450, family 4, subfamily F, polypeptide 2
chr19_+_2249308 0.13 ENST00000592877.1
ENST00000221496.4
 AMH
 anti-Mullerian hormone
chr2_-_46769694 0.13 ENST00000522587.1
 ATP6V1E2
 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr3_+_118892362 0.12 ENST00000497685.1
ENST00000264234.3
 UPK1B
 uroplakin 1B
chr3_+_44626446 0.12 ENST00000441021.1
ENST00000322734.2
 ZNF660
 zinc finger protein 660
chr2_+_11752379 0.12 ENST00000396123.1
 GREB1
 growth regulation by estrogen in breast cancer 1
chr17_-_34079897 0.12 ENST00000254466.6
ENST00000587565.1
 GAS2L2
 growth arrest-specific 2 like 2
chr14_-_21493884 0.12 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
 NDRG2
 NDRG family member 2
chr6_+_90604188 0.12 ENST00000369352.1
 GJA10
 gap junction protein, alpha 10, 62kDa
chr2_+_37571845 0.12 ENST00000537448.1
 QPCT
 glutaminyl-peptide cyclotransferase
chr1_-_153348067 0.12 ENST00000368737.3
 S100A12
 S100 calcium binding protein A12
chr19_-_42759300 0.12 ENST00000222329.4
 ERF
 Ets2 repressor factor
chr16_-_32688053 0.12 ENST00000398682.4
 TP53TG3
 TP53 target 3
chr19_+_14640372 0.11 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
 TECR
 trans-2,3-enoyl-CoA reductase
chr14_-_105531759 0.11 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
 GPR132
 G protein-coupled receptor 132
chr2_-_230933709 0.11 ENST00000436869.1
ENST00000295190.4
 SLC16A14
 solute carrier family 16, member 14
chr17_-_41132088 0.11 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
 PTGES3L
PTGES3L-AARSD1
 prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr16_+_2521500 0.11 ENST00000293973.1
 NTN3
 netrin 3
chr13_+_47127293 0.11 ENST00000311191.6
 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
chr12_+_50451331 0.11 ENST00000228468.4
 ASIC1
 acid-sensing (proton-gated) ion channel 1
chr16_+_32264040 0.10 ENST00000398664.3
 TP53TG3D
 TP53 target 3D
chr6_+_138725343 0.10 ENST00000607197.1
ENST00000367697.3
 HEBP2
 heme binding protein 2
chr6_-_117086873 0.10 ENST00000368557.4
 FAM162B
 family with sequence similarity 162, member B
chr17_-_7307358 0.10 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
 TMEM256
TMEM256-PLSCR3
 transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr1_-_1356628 0.10 ENST00000442470.1
ENST00000537107.1
 ANKRD65
 ankyrin repeat domain 65
chr21_+_34775698 0.10 ENST00000381995.1
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr16_+_9185450 0.10 ENST00000327827.7
 C16orf72
 chromosome 16 open reading frame 72
chr12_-_53242770 0.10 ENST00000304620.4
ENST00000547110.1
 KRT78
 keratin 78
chr3_+_52017454 0.09 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
 ACY1
 aminoacylase 1
chr7_-_155601766 0.09 ENST00000430104.1
 SHH
 sonic hedgehog
chr17_+_41476327 0.09 ENST00000320033.4
 ARL4D
 ADP-ribosylation factor-like 4D
chr10_+_103825080 0.09 ENST00000299238.5
 HPS6
 Hermansky-Pudlak syndrome 6
chrX_-_8700171 0.09 ENST00000262648.3
 KAL1
 Kallmann syndrome 1 sequence
chr3_-_125803105 0.09 ENST00000346785.5
ENST00000315891.6
 SLC41A3
 solute carrier family 41, member 3
chr19_+_11649532 0.09 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
 CNN1
 calponin 1, basic, smooth muscle
chr3_-_197282821 0.09 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
 BDH1
 3-hydroxybutyrate dehydrogenase, type 1
chr17_+_80416050 0.09 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
 NARF
 nuclear prelamin A recognition factor
chr20_+_52824367 0.09 ENST00000371419.2
 PFDN4
 prefoldin subunit 4
chr10_-_13276329 0.09 ENST00000378681.3
ENST00000463405.2
 UCMA
 upper zone of growth plate and cartilage matrix associated
chr16_+_765092 0.09 ENST00000568223.2
 METRN
 meteorin, glial cell differentiation regulator
chr19_-_38397285 0.08 ENST00000303868.5
 WDR87
 WD repeat domain 87
chr16_-_4664860 0.08 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
 UBALD1
 UBA-like domain containing 1
chr1_+_87595433 0.08 ENST00000469312.2
ENST00000490006.2
 RP5-1052I5.1
 long intergenic non-protein coding RNA 1140
chr19_-_38397228 0.08 ENST00000447313.2
 WDR87
 WD repeat domain 87
chr15_-_79383102 0.08 ENST00000558480.2
ENST00000419573.3
 RASGRF1
 Ras protein-specific guanine nucleotide-releasing factor 1
chr2_+_169312350 0.08 ENST00000305747.6
 CERS6
 ceramide synthase 6
chr22_-_18257178 0.08 ENST00000342111.5
 BID
 BH3 interacting domain death agonist
chr7_-_752074 0.08 ENST00000360274.4
 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_+_27078219 0.08 ENST00000418886.1
 C16orf82
 chromosome 16 open reading frame 82
chr1_-_40157345 0.08 ENST00000372844.3
 HPCAL4
 hippocalcin like 4
chr19_-_2702681 0.08 ENST00000382159.3
 GNG7
 guanine nucleotide binding protein (G protein), gamma 7
chr17_-_42200996 0.08 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
 HDAC5
 histone deacetylase 5
chr1_+_44412577 0.08 ENST00000372343.3
 IPO13
 importin 13
chr19_+_17337406 0.08 ENST00000597836.1
 OCEL1
 occludin/ELL domain containing 1
chr17_-_39280419 0.08 ENST00000394014.1
 KRTAP4-12
 keratin associated protein 4-12
chr3_+_111578131 0.08 ENST00000498699.1
 PHLDB2
 pleckstrin homology-like domain, family B, member 2
chr19_+_45251804 0.08 ENST00000164227.5
 BCL3
 B-cell CLL/lymphoma 3
chr21_+_42539701 0.08 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
 BACE2
 beta-site APP-cleaving enzyme 2
chr8_-_104427313 0.08 ENST00000297578.4
 SLC25A32
 solute carrier family 25 (mitochondrial folate carrier), member 32
chr16_-_68014732 0.08 ENST00000268793.4
 DPEP3
 dipeptidase 3
chr7_+_140373619 0.08 ENST00000483369.1
 ADCK2
 aarF domain containing kinase 2
chr19_+_56186557 0.08 ENST00000270460.6
 EPN1
 epsin 1
chr16_+_691792 0.07 ENST00000307650.4
 FAM195A
 family with sequence similarity 195, member A
chr9_-_34710066 0.07 ENST00000378792.1
ENST00000259607.2
 CCL21
 chemokine (C-C motif) ligand 21
chr9_+_139847347 0.07 ENST00000371632.3
 LCN12
 lipocalin 12
chr14_-_21493649 0.07 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
 NDRG2
 NDRG family member 2
chr9_-_98279241 0.07 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
 PTCH1
 patched 1
chr17_+_64831228 0.07 ENST00000533854.1
 CACNG5
 calcium channel, voltage-dependent, gamma subunit 5
chr13_+_47127322 0.07 ENST00000389798.3
 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
chr4_-_48082192 0.07 ENST00000507351.1
 TXK
 TXK tyrosine kinase
chr19_-_3479086 0.07 ENST00000587847.1
 C19orf77
 chromosome 19 open reading frame 77
chr16_+_33204980 0.07 ENST00000561509.1
 TP53TG3C
 TP53 target 3C
chr7_+_140372953 0.07 ENST00000072869.4
ENST00000476491.1
 ADCK2
 aarF domain containing kinase 2
chr3_+_4535025 0.07 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
 ITPR1
 inositol 1,4,5-trisphosphate receptor, type 1
chr1_-_27701307 0.07 ENST00000270879.4
ENST00000354982.2
 FCN3
 ficolin (collagen/fibrinogen domain containing) 3
chr7_+_29237354 0.07 ENST00000546235.1
 CHN2
 chimerin 2
chr19_-_55669093 0.07 ENST00000344887.5
 TNNI3
 troponin I type 3 (cardiac)
chr21_-_45671014 0.06 ENST00000436357.1
 DNMT3L
 DNA (cytosine-5-)-methyltransferase 3-like
chr7_-_130080977 0.06 ENST00000223208.5
 CEP41
 centrosomal protein 41kDa
chr19_-_19249255 0.06 ENST00000587583.2
ENST00000450333.2
ENST00000587096.1
ENST00000162044.9
ENST00000592369.1
ENST00000587915.1
 TMEM161A
 transmembrane protein 161A
chr2_+_169312725 0.06 ENST00000392687.4
 CERS6
 ceramide synthase 6
chr22_-_30685596 0.06 ENST00000404953.3
ENST00000407689.3
 GATSL3
 GATS protein-like 3
chr15_+_90234028 0.06 ENST00000268130.7
ENST00000560294.1
ENST00000558000.1
 WDR93
 WD repeat domain 93
chr19_+_17337473 0.06 ENST00000598068.1
 OCEL1
 occludin/ELL domain containing 1
chr21_+_34775181 0.06 ENST00000290219.6
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_+_87284675 0.06 ENST00000376208.1
ENST00000304053.6
ENST00000277120.3
 NTRK2
 neurotrophic tyrosine kinase, receptor, type 2
chr20_+_35974532 0.06 ENST00000373578.2
 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr13_-_42535214 0.06 ENST00000379310.3
ENST00000281496.6
 VWA8
 von Willebrand factor A domain containing 8
chr12_-_49110613 0.06 ENST00000261900.3
 CCNT1
 cyclin T1
chr22_-_38794490 0.06 ENST00000400206.2
 CSNK1E
 casein kinase 1, epsilon
chr2_-_131357123 0.06 ENST00000259216.4
 CFC1
 cripto, FRL-1, cryptic family 1
chr10_+_102747783 0.06 ENST00000311916.2
ENST00000370228.1
 C10orf2
 chromosome 10 open reading frame 2
chr3_-_193096600 0.06 ENST00000446087.1
ENST00000342358.4
 ATP13A5
 ATPase type 13A5
chr17_-_27224621 0.06 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
 FLOT2
 flotillin 2
chr17_+_7461580 0.06 ENST00000483039.1
ENST00000396542.1
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chr19_+_45254529 0.05 ENST00000444487.1
 BCL3
 B-cell CLL/lymphoma 3
chr2_-_85829496 0.05 ENST00000409668.1
 TMEM150A
 transmembrane protein 150A
chr19_-_54784937 0.05 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
 LILRB2
 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr4_-_106394866 0.05 ENST00000502596.1
 PPA2
 pyrophosphatase (inorganic) 2
chr7_-_98741714 0.05 ENST00000361125.1
 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
chr17_+_7210898 0.05 ENST00000572815.1
 EIF5A
 eukaryotic translation initiation factor 5A
chr6_-_39290744 0.05 ENST00000507712.1
 KCNK16
 potassium channel, subfamily K, member 16
chr22_-_19974616 0.05 ENST00000344269.3
ENST00000401994.1
ENST00000406522.1
 ARVCF
 armadillo repeat gene deleted in velocardiofacial syndrome
chr2_-_38604398 0.05 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
 ATL2
 atlastin GTPase 2
chr14_+_22670455 0.05 ENST00000390460.1
 TRAV26-2
 T cell receptor alpha variable 26-2
chr9_+_127539481 0.05 ENST00000373580.3
 OLFML2A
 olfactomedin-like 2A
chr21_+_34775772 0.05 ENST00000405436.1
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_45582453 0.05 ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
ENST00000587566.1
 GEMIN7
MARK4
 gem (nuclear organelle) associated protein 7
MAP/microtubule affinity-regulating kinase 4
chr20_-_23969416 0.05 ENST00000335694.4
 GGTLC1
 gamma-glutamyltransferase light chain 1
chr6_-_80247105 0.05 ENST00000369846.4
 LCA5
 Leber congenital amaurosis 5
chr19_-_10444188 0.05 ENST00000293677.6
 RAVER1
 ribonucleoprotein, PTB-binding 1
chr17_+_7788104 0.05 ENST00000380358.4
 CHD3
 chromodomain helicase DNA binding protein 3
chr3_+_153839149 0.05 ENST00000465093.1
ENST00000465817.1
 ARHGEF26
 Rho guanine nucleotide exchange factor (GEF) 26
chr1_+_148928291 0.05 ENST00000420597.1
ENST00000452399.1
ENST00000294715.2
ENST00000539543.1
 RP11-14N7.2
 RP11-14N7.2
chr17_-_74068707 0.05 ENST00000307877.2
 SRP68
 signal recognition particle 68kDa
chr20_+_48807351 0.05 ENST00000303004.3
 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
chr17_-_5138099 0.05 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
 SCIMP
 SLP adaptor and CSK interacting membrane protein
chr1_-_115300579 0.05 ENST00000358528.4
ENST00000525132.1
 CSDE1
 cold shock domain containing E1, RNA-binding
chr1_-_24127256 0.05 ENST00000418277.1
 GALE
 UDP-galactose-4-epimerase
chr2_+_228336849 0.05 ENST00000409979.2
ENST00000310078.8
 AGFG1
 ArfGAP with FG repeats 1
chr1_-_201123586 0.05 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
 TMEM9
 transmembrane protein 9
chrX_-_102319092 0.05 ENST00000372728.3
 BEX1
 brain expressed, X-linked 1
chr22_+_18834324 0.05 ENST00000342005.4
 AC008132.13
 Uncharacterized protein
chr1_+_150954493 0.05 ENST00000368947.4
 ANXA9
 annexin A9
chrX_-_10557949 0.05 ENST00000380780.1
 MID1
 midline 1 (Opitz/BBB syndrome)
chr9_+_103189536 0.05 ENST00000374885.1
 MSANTD3
 Myb/SANT-like DNA-binding domain containing 3
chr15_-_90233866 0.05 ENST00000561257.1
 PEX11A
 peroxisomal biogenesis factor 11 alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2 0.6 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 0.5 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.2 0.5 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.8 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.8 GO:2001268 positive regulation of keratinocyte migration(GO:0051549) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.2 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.5 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.0 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.0 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0030497 fatty acid elongation(GO:0030497)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.4 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.5 GO:0031014 troponin T binding(GO:0031014)
0.0 0.7 GO:0019841 retinol binding(GO:0019841)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions