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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for HOXB4_LHX9

Z-value: 1.21

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Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
HOXB4
ENSG00000182742.5 HOXB4
LHX9
ENSG00000143355.11 LHX9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB4hg19_v2_chr17_-_46657473_466574730.921.0e-03Click!
LHX9hg19_v2_chr1_+_197881592_197881635-0.571.4e-01Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_105845674 2.38 ENST00000353479.5
ENST00000369733.3
 COL17A1
 collagen, type XVII, alpha 1
chr19_-_36001113 1.82 ENST00000434389.1
 DMKN
 dermokine
chr12_-_8803128 1.61 ENST00000543467.1
 MFAP5
 microfibrillar associated protein 5
chr2_-_161056762 1.40 ENST00000428609.2
ENST00000409967.2
 ITGB6
 integrin, beta 6
chr2_-_161056802 1.39 ENST00000283249.2
ENST00000409872.1
 ITGB6
 integrin, beta 6
chr18_+_29027696 1.29 ENST00000257189.4
 DSG3
 desmoglein 3
chr1_+_160370344 1.25 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chr8_-_41166953 1.08 ENST00000220772.3
 SFRP1
 secreted frizzled-related protein 1
chr1_+_62439037 1.07 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr5_+_66300446 0.90 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr1_+_28261492 0.85 ENST00000373894.3
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr3_-_151034734 0.74 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr18_+_21452964 0.74 ENST00000587184.1
 LAMA3
 laminin, alpha 3
chr5_+_89770664 0.73 ENST00000503973.1
ENST00000399107.1
 POLR3G
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr18_+_21452804 0.72 ENST00000269217.6
 LAMA3
 laminin, alpha 3
chr5_+_89770696 0.72 ENST00000504930.1
ENST00000514483.1
 POLR3G
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr10_+_24755416 0.71 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
 KIAA1217
 KIAA1217
chr2_+_182850551 0.65 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
 PPP1R1C
 protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_5323226 0.62 ENST00000380224.1
 OR51B4
 olfactory receptor, family 51, subfamily B, member 4
chr11_-_119991589 0.62 ENST00000526881.1
 TRIM29
 tripartite motif containing 29
chr10_+_6779326 0.59 ENST00000417112.1
 RP11-554I8.2
 RP11-554I8.2
chr6_+_130339710 0.57 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr17_-_39743139 0.57 ENST00000167586.6
 KRT14
 keratin 14
chr14_-_67878917 0.57 ENST00000216446.4
 PLEK2
 pleckstrin 2
chr16_-_28634874 0.55 ENST00000395609.1
ENST00000350842.4
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr18_-_74839891 0.53 ENST00000581878.1
 MBP
 myelin basic protein
chr2_+_182850743 0.51 ENST00000409702.1
 PPP1R1C
 protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_-_242612779 0.50 ENST00000427495.1
 PLD5
 phospholipase D family, member 5
chr7_-_25702669 0.48 ENST00000446840.1
 AC003090.1
 AC003090.1
chr4_-_74486109 0.45 ENST00000395777.2
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr3_+_111718036 0.44 ENST00000455401.2
 TAGLN3
 transgelin 3
chr8_+_105235572 0.44 ENST00000523362.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr3_+_111717600 0.43 ENST00000273368.4
 TAGLN3
 transgelin 3
chr4_-_74486217 0.43 ENST00000335049.5
ENST00000307439.5
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr9_+_124329336 0.41 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
 DAB2IP
 DAB2 interacting protein
chr3_+_111718173 0.41 ENST00000494932.1
 TAGLN3
 transgelin 3
chr3_+_111717511 0.39 ENST00000478951.1
ENST00000393917.2
 TAGLN3
 transgelin 3
chr8_-_125577940 0.39 ENST00000519168.1
ENST00000395508.2
 MTSS1
 metastasis suppressor 1
chr4_+_76481258 0.39 ENST00000311623.4
ENST00000435974.2
 C4orf26
 chromosome 4 open reading frame 26
chr2_+_102615416 0.39 ENST00000393414.2
 IL1R2
 interleukin 1 receptor, type II
chr5_-_35938674 0.39 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
 CAPSL
 calcyphosine-like
chr4_-_159956333 0.38 ENST00000434826.2
 C4orf45
 chromosome 4 open reading frame 45
chr3_-_141747950 0.37 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_90211643 0.37 ENST00000390277.2
 IGKV3D-11
 immunoglobulin kappa variable 3D-11
chr5_+_140220769 0.35 ENST00000531613.1
ENST00000378123.3
 PCDHA8
 protocadherin alpha 8
chr17_-_19015945 0.34 ENST00000573866.2
 SNORD3D
 small nucleolar RNA, C/D box 3D
chr6_-_32806506 0.33 ENST00000374897.2
ENST00000452392.2
 TAP2
TAP2
 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr4_-_90757364 0.33 ENST00000508895.1
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_152784447 0.33 ENST00000360090.3
 LCE1B
 late cornified envelope 1B
chr19_-_36304201 0.30 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr20_+_31805131 0.30 ENST00000375454.3
ENST00000375452.3
 BPIFA3
 BPI fold containing family A, member 3
chr11_-_128894053 0.29 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr6_+_26365443 0.29 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
 BTN3A2
 butyrophilin, subfamily 3, member A2
chr16_-_30122717 0.28 ENST00000566613.1
 GDPD3
 glycerophosphodiester phosphodiesterase domain containing 3
chr2_+_90273679 0.28 ENST00000423080.2
 IGKV3D-7
 immunoglobulin kappa variable 3D-7
chrX_-_100662881 0.27 ENST00000218516.3
 GLA
 galactosidase, alpha
chr14_+_22670455 0.27 ENST00000390460.1
 TRAV26-2
 T cell receptor alpha variable 26-2
chr20_-_29978383 0.26 ENST00000339144.3
ENST00000376321.3
 DEFB119
 defensin, beta 119
chr14_+_103851712 0.26 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
 MARK3
 MAP/microtubule affinity-regulating kinase 3
chr11_-_104827425 0.26 ENST00000393150.3
 CASP4
 caspase 4, apoptosis-related cysteine peptidase
chr11_+_59522837 0.25 ENST00000437946.2
 STX3
 syntaxin 3
chr6_+_42584847 0.25 ENST00000372883.3
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr21_-_31538971 0.25 ENST00000286808.3
 CLDN17
 claudin 17
chr17_+_19091325 0.24 ENST00000584923.1
 SNORD3A
 small nucleolar RNA, C/D box 3A
chr11_-_107729887 0.24 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr11_-_75917569 0.24 ENST00000322563.3
 WNT11
 wingless-type MMTV integration site family, member 11
chr12_-_52604607 0.23 ENST00000551894.1
ENST00000553017.1
 C12orf80
 chromosome 12 open reading frame 80
chr11_+_55594695 0.23 ENST00000378397.1
 OR5L2
 olfactory receptor, family 5, subfamily L, member 2
chr7_+_115862858 0.23 ENST00000393481.2
 TES
 testis derived transcript (3 LIM domains)
chr4_+_119810134 0.22 ENST00000434046.2
 SYNPO2
 synaptopodin 2
chr4_-_74486347 0.22 ENST00000342081.3
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr1_+_196743912 0.22 ENST00000367425.4
 CFHR3
 complement factor H-related 3
chr2_-_130031335 0.22 ENST00000375987.3
 AC079586.1
 AC079586.1
chr3_-_191000172 0.22 ENST00000427544.2
 UTS2B
 urotensin 2B
chr2_-_89327228 0.21 ENST00000483158.1
 IGKV3-11
 immunoglobulin kappa variable 3-11
chr12_-_112279694 0.21 ENST00000443596.1
ENST00000442119.1
 MAPKAPK5-AS1
 MAPKAPK5 antisense RNA 1
chr20_-_50722183 0.21 ENST00000371523.4
 ZFP64
 ZFP64 zinc finger protein
chr7_-_111032971 0.20 ENST00000450877.1
 IMMP2L
 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr21_-_42219065 0.20 ENST00000400454.1
 DSCAM
 Down syndrome cell adhesion molecule
chrX_+_37639302 0.20 ENST00000545017.1
ENST00000536160.1
 CYBB
 cytochrome b-245, beta polypeptide
chr7_-_37024665 0.20 ENST00000396040.2
 ELMO1
 engulfment and cell motility 1
chr4_+_110749143 0.19 ENST00000317735.4
 RRH
 retinal pigment epithelium-derived rhodopsin homolog
chr12_+_81110684 0.19 ENST00000228644.3
 MYF5
 myogenic factor 5
chr11_-_46408107 0.19 ENST00000433765.2
 CHRM4
 cholinergic receptor, muscarinic 4
chr3_-_185538849 0.19 ENST00000421047.2
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr17_-_38821373 0.18 ENST00000394052.3
 KRT222
 keratin 222
chr3_-_141719195 0.18 ENST00000397991.4
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr19_+_11485333 0.18 ENST00000312423.2
 SWSAP1
 SWIM-type zinc finger 7 associated protein 1
chr14_+_31046959 0.17 ENST00000547532.1
ENST00000555429.1
 G2E3
 G2/M-phase specific E3 ubiquitin protein ligase
chr6_+_26402465 0.17 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
 BTN3A1
 butyrophilin, subfamily 3, member A1
chr14_-_72458326 0.17 ENST00000542853.1
 AC005477.1
 AC005477.1
chr14_+_24641062 0.17 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
 REC8
 REC8 meiotic recombination protein
chr2_+_234826016 0.17 ENST00000324695.4
ENST00000433712.2
 TRPM8
 transient receptor potential cation channel, subfamily M, member 8
chr2_+_90077680 0.17 ENST00000390270.2
 IGKV3D-20
 immunoglobulin kappa variable 3D-20
chr1_+_81771806 0.16 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr12_-_91451758 0.16 ENST00000266719.3
 KERA
 keratocan
chr15_-_72523924 0.16 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
 PKM
 pyruvate kinase, muscle
chr6_+_129204337 0.16 ENST00000421865.2
 LAMA2
 laminin, alpha 2
chr2_+_234637754 0.16 ENST00000482026.1
ENST00000609767.1
 UGT1A3
UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_102456277 0.16 ENST00000421882.1
 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
chr4_-_120243545 0.16 ENST00000274024.3
 FABP2
 fatty acid binding protein 2, intestinal
chr6_+_26402517 0.16 ENST00000414912.2
 BTN3A1
 butyrophilin, subfamily 3, member A1
chr14_-_104181771 0.15 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
 XRCC3
 X-ray repair complementing defective repair in Chinese hamster cells 3
chr12_-_22063787 0.15 ENST00000544039.1
 ABCC9
 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_-_29527702 0.15 ENST00000377050.4
 UBD
 ubiquitin D
chr4_-_39979576 0.15 ENST00000303538.8
ENST00000503396.1
 PDS5A
 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr10_+_695888 0.14 ENST00000441152.2
 PRR26
 proline rich 26
chr6_+_3259148 0.14 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
 PSMG4
 proteasome (prosome, macropain) assembly chaperone 4
chr2_+_102953608 0.14 ENST00000311734.2
ENST00000409584.1
 IL1RL1
 interleukin 1 receptor-like 1
chr8_-_33424636 0.14 ENST00000256257.1
 RNF122
 ring finger protein 122
chr1_-_67266939 0.14 ENST00000304526.2
 INSL5
 insulin-like 5
chr13_+_32313658 0.14 ENST00000380314.1
ENST00000298386.2
 RXFP2
 relaxin/insulin-like family peptide receptor 2
chr4_-_103997862 0.14 ENST00000394785.3
 SLC9B2
 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr4_-_103998439 0.14 ENST00000503230.1
ENST00000503818.1
 SLC9B2
 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr2_+_202047596 0.14 ENST00000286186.6
ENST00000360132.3
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr4_+_156587853 0.13 ENST00000506455.1
ENST00000511108.1
 GUCY1A3
 guanylate cyclase 1, soluble, alpha 3
chr7_-_87856280 0.13 ENST00000490437.1
ENST00000431660.1
 SRI
 sorcin
chr5_+_36152179 0.13 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_+_127585093 0.13 ENST00000368695.1
ENST00000368693.1
 FANK1
 fibronectin type III and ankyrin repeat domains 1
chr15_-_82641706 0.13 ENST00000439287.4
 GOLGA6L10
 golgin A6 family-like 10
chr7_-_87856303 0.13 ENST00000394641.3
 SRI
 sorcin
chr12_+_20963632 0.13 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr3_-_20053741 0.13 ENST00000389050.4
 PP2D1
 protein phosphatase 2C-like domain containing 1
chr9_-_77643307 0.13 ENST00000376834.3
ENST00000376830.3
 C9orf41
 chromosome 9 open reading frame 41
chr10_+_101491968 0.13 ENST00000370476.5
ENST00000370472.4
 CUTC
 cutC copper transporter
chrX_-_71458802 0.13 ENST00000373657.1
ENST00000334463.3
 ERCC6L
 excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr2_-_128284020 0.12 ENST00000295321.4
ENST00000455721.2
 IWS1
 IWS1 homolog (S. cerevisiae)
chr11_+_59824127 0.12 ENST00000278865.3
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chrX_+_100663243 0.12 ENST00000316594.5
 HNRNPH2
 heterogeneous nuclear ribonucleoprotein H2 (H')
chr4_+_100432161 0.12 ENST00000326581.4
ENST00000514652.1
 C4orf17
 chromosome 4 open reading frame 17
chr3_-_160823040 0.12 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr12_+_10163231 0.12 ENST00000396502.1
ENST00000338896.5
 CLEC12B
 C-type lectin domain family 12, member B
chr8_+_50824233 0.12 ENST00000522124.1
 SNTG1
 syntrophin, gamma 1
chr4_+_86525299 0.12 ENST00000512201.1
 ARHGAP24
 Rho GTPase activating protein 24
chr13_+_97928395 0.12 ENST00000445661.2
 MBNL2
 muscleblind-like splicing regulator 2
chr12_+_112279782 0.12 ENST00000550735.2
 MAPKAPK5
 mitogen-activated protein kinase-activated protein kinase 5
chr3_-_160823158 0.12 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_-_4938712 0.12 ENST00000254853.5
ENST00000424747.1
 SLC52A1
 solute carrier family 52 (riboflavin transporter), member 1
chr2_+_202047843 0.12 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr2_-_43266680 0.12 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
 AC016735.2
 AC016735.2
chr5_+_36152091 0.12 ENST00000274254.5
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr4_+_108745711 0.12 ENST00000394684.4
 SGMS2
 sphingomyelin synthase 2
chr9_-_95640218 0.11 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
 ZNF484
 zinc finger protein 484
chr15_+_66679155 0.11 ENST00000307102.5
 MAP2K1
 mitogen-activated protein kinase kinase 1
chr8_-_101571964 0.11 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
 ANKRD46
 ankyrin repeat domain 46
chr8_+_107738343 0.11 ENST00000521592.1
 OXR1
 oxidation resistance 1
chr17_+_18086392 0.11 ENST00000541285.1
 ALKBH5
 alkB, alkylation repair homolog 5 (E. coli)
chr16_-_28608364 0.11 ENST00000533150.1
 SULT1A2
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr18_-_51751132 0.11 ENST00000256429.3
 MBD2
 methyl-CpG binding domain protein 2
chr1_+_161691353 0.11 ENST00000367948.2
 FCRLB
 Fc receptor-like B
chr9_+_117904097 0.11 ENST00000374016.1
 DEC1
 deleted in esophageal cancer 1
chr2_-_169887827 0.11 ENST00000263817.6
 ABCB11
 ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr5_+_36152163 0.11 ENST00000274255.6
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr2_-_89385283 0.11 ENST00000390252.2
 IGKV3-15
 immunoglobulin kappa variable 3-15
chr11_+_7626950 0.11 ENST00000530181.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_+_15489603 0.11 ENST00000568766.1
ENST00000287594.7
 RP11-1021N1.1
MPV17L
 Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr11_+_59824060 0.11 ENST00000395032.2
ENST00000358152.2
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr5_+_55149150 0.10 ENST00000297015.3
 IL31RA
 interleukin 31 receptor A
chr1_-_201140673 0.10 ENST00000367333.2
 TMEM9
 transmembrane protein 9
chr14_+_56584414 0.10 ENST00000559044.1
 PELI2
 pellino E3 ubiquitin protein ligase family member 2
chr6_+_30585486 0.10 ENST00000259873.4
ENST00000506373.2
 MRPS18B
 mitochondrial ribosomal protein S18B
chr21_-_15583165 0.10 ENST00000536861.1
 LIPI
 lipase, member I
chr20_+_30697298 0.10 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr8_-_101571933 0.10 ENST00000520311.1
 ANKRD46
 ankyrin repeat domain 46
chr4_+_80584903 0.10 ENST00000506460.1
 RP11-452C8.1
 RP11-452C8.1
chr12_+_20963647 0.10 ENST00000381545.3
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr4_-_170948361 0.10 ENST00000393702.3
 MFAP3L
 microfibrillar-associated protein 3-like
chr2_+_87565634 0.10 ENST00000421835.2
 IGKV3OR2-268
 immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr14_+_23938891 0.10 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
 NGDN
 neuroguidin, EIF4E binding protein
chr11_+_118398178 0.10 ENST00000302783.4
ENST00000539546.1
 TTC36
 tetratricopeptide repeat domain 36
chr2_-_90538397 0.10 ENST00000443397.3
 RP11-685N3.1
 Uncharacterized protein
chr9_+_125132803 0.10 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr5_+_1225470 0.10 ENST00000324642.3
ENST00000296821.4
 SLC6A18
 solute carrier family 6 (neutral amino acid transporter), member 18
chr19_-_3557570 0.09 ENST00000355415.2
 MFSD12
 major facilitator superfamily domain containing 12
chr13_+_48611665 0.09 ENST00000258662.2
 NUDT15
 nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr12_-_112123524 0.09 ENST00000327551.6
 BRAP
 BRCA1 associated protein
chr1_-_39339777 0.09 ENST00000397572.2
 MYCBP
 MYC binding protein
chr7_-_44580861 0.09 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
 NPC1L1
 NPC1-like 1
chr4_-_103998060 0.09 ENST00000339611.4
 SLC9B2
 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr7_-_44122063 0.09 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
 POLM
 polymerase (DNA directed), mu
chr1_-_205091115 0.09 ENST00000264515.6
ENST00000367164.1
 RBBP5
 retinoblastoma binding protein 5
chr3_-_194072019 0.09 ENST00000429275.1
ENST00000323830.3
 CPN2
 carboxypeptidase N, polypeptide 2
chr3_+_139063372 0.09 ENST00000478464.1
 MRPS22
 mitochondrial ribosomal protein S22
chr3_+_23851928 0.09 ENST00000467766.1
ENST00000424381.1
 UBE2E1
 ubiquitin-conjugating enzyme E2E 1
chr15_+_58702742 0.08 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr16_-_29934558 0.08 ENST00000568995.1
ENST00000566413.1
 KCTD13
 potassium channel tetramerization domain containing 13
chr7_+_107224364 0.08 ENST00000491150.1
 BCAP29
 B-cell receptor-associated protein 29
chr6_+_29079668 0.08 ENST00000377169.1
 OR2J3
 olfactory receptor, family 2, subfamily J, member 3
chr7_+_150020329 0.08 ENST00000323078.7
 LRRC61
 leucine rich repeat containing 61
chr15_-_55489097 0.08 ENST00000260443.4
 RSL24D1
 ribosomal L24 domain containing 1
chr14_-_106552755 0.08 ENST00000390600.2
 IGHV3-9
 immunoglobulin heavy variable 3-9
chr5_+_140557371 0.08 ENST00000239444.2
 PCDHB8
 protocadherin beta 8
chr2_-_101925055 0.08 ENST00000295317.3
 RNF149
 ring finger protein 149
chr1_-_197115818 0.08 ENST00000367409.4
ENST00000294732.7
 ASPM
 asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_-_81399411 0.08 ENST00000423064.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_+_1710484 0.08 ENST00000313871.3
ENST00000381261.3
 AKAP17A
 A kinase (PRKA) anchor protein 17A
chr10_+_90424196 0.08 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
 LIPF
 lipase, gastric
chr1_-_92952433 0.08 ENST00000294702.5
 GFI1
 growth factor independent 1 transcription repressor
chr2_-_136678123 0.07 ENST00000422708.1
 DARS
 aspartyl-tRNA synthetase
chr11_+_122753391 0.07 ENST00000307257.6
ENST00000227349.2
 C11orf63
 chromosome 11 open reading frame 63

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.4 1.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.3 1.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 2.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.2 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.2 4.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.4 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 1.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 1.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.0 GO:0070640 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 1.3 GO:0060187 cell pole(GO:0060187)
0.2 1.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 2.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0097196 Shu complex(GO:0097196)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 2.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway