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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for HOXD11_HOXA11

Z-value: 0.39

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Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
HOXD11
ENSG00000128713.11 HOXD11
HOXA11
ENSG00000005073.5 HOXA11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD11hg19_v2_chr2_+_176972000_176972025-0.393.4e-01Click!
HOXA11hg19_v2_chr7_-_27224795_27224840,
hg19_v2_chr7_-_27224842_27224872		0.294.9e-01Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_183774240 0.74 ENST00000360851.3
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr8_+_97597148 0.60 ENST00000521590.1
 SDC2
 syndecan 2
chr5_+_148521381 0.52 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr3_-_18480260 0.49 ENST00000454909.2
 SATB1
 SATB homeobox 1
chr1_+_244515930 0.48 ENST00000366537.1
ENST00000308105.4
 C1orf100
 chromosome 1 open reading frame 100
chr5_-_111093167 0.47 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr5_-_20575959 0.45 ENST00000507958.1
 CDH18
 cadherin 18, type 2
chr6_+_32812568 0.42 ENST00000414474.1
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr12_-_91546926 0.37 ENST00000550758.1
 DCN
 decorin
chr19_+_46367518 0.37 ENST00000302177.2
 FOXA3
 forkhead box A3
chr1_+_52682052 0.35 ENST00000371591.1
 ZFYVE9
 zinc finger, FYVE domain containing 9
chr14_-_51027838 0.35 ENST00000555216.1
 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
chr8_+_107738343 0.34 ENST00000521592.1
 OXR1
 oxidation resistance 1
chr8_-_116504448 0.32 ENST00000518018.1
 TRPS1
 trichorhinophalangeal syndrome I
chr17_-_53800217 0.32 ENST00000424486.2
 TMEM100
 transmembrane protein 100
chr1_-_72566613 0.30 ENST00000306821.3
 NEGR1
 neuronal growth regulator 1
chr19_-_10446449 0.28 ENST00000592439.1
 ICAM3
 intercellular adhesion molecule 3
chr17_-_66951474 0.28 ENST00000269080.2
 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_47219733 0.27 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
 SLC38A4
 solute carrier family 38, member 4
chr5_-_111093759 0.27 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
 NREP
 neuronal regeneration related protein
chr3_+_157154578 0.26 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr1_+_79086088 0.26 ENST00000370751.5
ENST00000342282.3
 IFI44L
 interferon-induced protein 44-like
chr1_+_78769549 0.25 ENST00000370758.1
 PTGFR
 prostaglandin F receptor (FP)
chr5_+_67586465 0.25 ENST00000336483.5
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_-_52859046 0.25 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
 GSTA4
 glutathione S-transferase alpha 4
chr8_-_93029865 0.25 ENST00000422361.2
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_12656715 0.25 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
 SPIRE1
 spire-type actin nucleation factor 1
chr1_-_160231451 0.24 ENST00000495887.1
 DCAF8
 DDB1 and CUL4 associated factor 8
chr7_+_138915102 0.24 ENST00000486663.1
 UBN2
 ubinuclein 2
chr3_-_156534754 0.24 ENST00000472943.1
ENST00000473352.1
 LINC00886
 long intergenic non-protein coding RNA 886
chr4_+_146539415 0.23 ENST00000281317.5
 MMAA
 methylmalonic aciduria (cobalamin deficiency) cblA type
chr12_-_91573132 0.23 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chr12_-_6579833 0.23 ENST00000396308.3
 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
chr4_+_41258786 0.22 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_-_167059830 0.22 ENST00000367868.3
 GPA33
 glycoprotein A33 (transmembrane)
chr12_-_6580094 0.22 ENST00000361716.3
 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
chr8_-_38326119 0.21 ENST00000356207.5
ENST00000326324.6
 FGFR1
 fibroblast growth factor receptor 1
chr10_+_85933494 0.21 ENST00000372126.3
 C10orf99
 chromosome 10 open reading frame 99
chr8_-_38326139 0.20 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
 FGFR1
 fibroblast growth factor receptor 1
chr10_-_90712520 0.20 ENST00000224784.6
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr1_+_151735431 0.20 ENST00000321531.5
ENST00000315067.8
 OAZ3
 ornithine decarboxylase antizyme 3
chr12_-_10573149 0.20 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
 KLRC3
 killer cell lectin-like receptor subfamily C, member 3
chr2_+_109204743 0.19 ENST00000332345.6
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr14_-_60097297 0.19 ENST00000395090.1
 RTN1
 reticulon 1
chr2_+_33359646 0.19 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr12_-_56236734 0.19 ENST00000548629.1
 MMP19
 matrix metallopeptidase 19
chr12_-_76879852 0.19 ENST00000548341.1
 OSBPL8
 oxysterol binding protein-like 8
chr3_-_100712352 0.18 ENST00000471714.1
ENST00000284322.5
 ABI3BP
 ABI family, member 3 (NESH) binding protein
chr20_+_12989596 0.18 ENST00000434210.1
ENST00000399002.2
 SPTLC3
 serine palmitoyltransferase, long chain base subunit 3
chr7_+_141811539 0.18 ENST00000550469.2
ENST00000477922.3
 RP11-1220K2.2
 Putative inactive maltase-glucoamylase-like protein LOC93432
chr17_+_66521936 0.18 ENST00000592800.1
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_95244781 0.18 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr2_+_33359687 0.18 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr1_+_192127578 0.18 ENST00000367460.3
 RGS18
 regulator of G-protein signaling 18
chr15_-_99789736 0.17 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
 TTC23
 tetratricopeptide repeat domain 23
chr12_-_6579808 0.17 ENST00000535180.1
ENST00000400911.3
 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
chr2_+_201450591 0.17 ENST00000374700.2
 AOX1
 aldehyde oxidase 1
chr7_+_150065278 0.17 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
 REPIN1
 replication initiator 1
chr9_-_130829588 0.17 ENST00000373078.4
 NAIF1
 nuclear apoptosis inducing factor 1
chr9_-_21305312 0.17 ENST00000259555.4
 IFNA5
 interferon, alpha 5
chr12_+_6833437 0.17 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
 COPS7A
 COP9 signalosome subunit 7A
chr12_+_6833237 0.17 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
 COPS7A
 COP9 signalosome subunit 7A
chr14_-_60097524 0.17 ENST00000342503.4
 RTN1
 reticulon 1
chr11_+_64001962 0.17 ENST00000309422.2
 VEGFB
 vascular endothelial growth factor B
chr3_+_151531810 0.17 ENST00000232892.7
 AADAC
 arylacetamide deacetylase
chr9_-_123812542 0.16 ENST00000223642.1
 C5
 complement component 5
chr12_-_49418407 0.16 ENST00000526209.1
 KMT2D
 lysine (K)-specific methyltransferase 2D
chr10_-_90751038 0.16 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr6_-_26189304 0.16 ENST00000340756.2
 HIST1H4D
 histone cluster 1, H4d
chr9_+_101705893 0.16 ENST00000375001.3
 COL15A1
 collagen, type XV, alpha 1
chr22_-_39190116 0.16 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
 SUN2
DNAL4
 Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr11_-_26593677 0.16 ENST00000527569.1
 MUC15
 mucin 15, cell surface associated
chr4_+_70894130 0.16 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3
 histatin 3
chrX_+_73164167 0.16 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
 JPX
 JPX transcript, XIST activator (non-protein coding)
chrX_+_16668278 0.15 ENST00000380200.3
 S100G
 S100 calcium binding protein G
chr9_+_2029019 0.15 ENST00000382194.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_28571015 0.15 ENST00000375719.3
ENST00000375732.1
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr8_+_16884740 0.15 ENST00000318063.5
 MICU3
 mitochondrial calcium uptake family, member 3
chr19_-_54618650 0.15 ENST00000391757.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr1_+_65730385 0.15 ENST00000263441.7
ENST00000395325.3
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_-_26593779 0.15 ENST00000529533.1
 MUC15
 mucin 15, cell surface associated
chr19_+_56152262 0.15 ENST00000325333.5
ENST00000590190.1
 ZNF580
 zinc finger protein 580
chr9_+_125133315 0.15 ENST00000223423.4
ENST00000362012.2
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_151739131 0.15 ENST00000400999.1
 OAZ3
 ornithine decarboxylase antizyme 3
chr2_-_190044480 0.15 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr15_+_67841330 0.14 ENST00000354498.5
 MAP2K5
 mitogen-activated protein kinase kinase 5
chr6_+_132873832 0.14 ENST00000275200.1
 TAAR8
 trace amine associated receptor 8
chr4_+_120056939 0.14 ENST00000307128.5
 MYOZ2
 myozenin 2
chr6_+_72922590 0.14 ENST00000523963.1
 RIMS1
 regulating synaptic membrane exocytosis 1
chr6_+_72922505 0.14 ENST00000401910.3
 RIMS1
 regulating synaptic membrane exocytosis 1
chr19_+_49468558 0.14 ENST00000331825.6
 FTL
 ferritin, light polypeptide
chr2_+_158114051 0.14 ENST00000259056.4
 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr2_-_3504587 0.14 ENST00000415131.1
 ADI1
 acireductone dioxygenase 1
chr17_-_67138015 0.13 ENST00000284425.2
ENST00000590645.1
 ABCA6
 ATP-binding cassette, sub-family A (ABC1), member 6
chr14_-_20774092 0.13 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
 TTC5
 tetratricopeptide repeat domain 5
chr21_+_17792672 0.13 ENST00000602620.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr2_+_28618532 0.13 ENST00000545753.1
 FOSL2
 FOS-like antigen 2
chr3_-_112356944 0.13 ENST00000461431.1
 CCDC80
 coiled-coil domain containing 80
chr4_+_71458012 0.13 ENST00000449493.2
 AMBN
 ameloblastin (enamel matrix protein)
chr3_-_99569821 0.13 ENST00000487087.1
 FILIP1L
 filamin A interacting protein 1-like
chr21_+_35736302 0.13 ENST00000290310.3
 KCNE2
 potassium voltage-gated channel, Isk-related family, member 2
chr19_-_54619006 0.13 ENST00000391759.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr15_+_67418047 0.13 ENST00000540846.2
 SMAD3
 SMAD family member 3
chr1_+_229440129 0.12 ENST00000366688.3
 SPHAR
 S-phase response (cyclin related)
chr3_-_67705006 0.12 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
chr6_-_87804815 0.12 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide
chrX_+_135251835 0.12 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr19_-_36233332 0.12 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
 IGFLR1
 IGF-like family receptor 1
chr9_-_73029540 0.12 ENST00000377126.2
 KLF9
 Kruppel-like factor 9
chr19_+_19626531 0.12 ENST00000507754.4
 NDUFA13
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr6_-_32157947 0.12 ENST00000375050.4
 PBX2
 pre-B-cell leukemia homeobox 2
chr3_-_123710199 0.11 ENST00000184183.4
 ROPN1
 rhophilin associated tail protein 1
chr8_+_77593448 0.11 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr6_-_25042231 0.11 ENST00000510784.2
 FAM65B
 family with sequence similarity 65, member B
chrX_+_36246735 0.11 ENST00000378653.3
 CXorf30
 chromosome X open reading frame 30
chr1_+_70876926 0.11 ENST00000370938.3
ENST00000346806.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chr12_+_70219052 0.11 ENST00000552032.2
ENST00000547771.2
 MYRFL
 myelin regulatory factor-like
chr11_+_19798964 0.11 ENST00000527559.2
 NAV2
 neuron navigator 2
chr6_-_52859968 0.11 ENST00000370959.1
 GSTA4
 glutathione S-transferase alpha 4
chr14_+_57671888 0.11 ENST00000391612.1
 AL391152.1
 AL391152.1
chr19_-_45982076 0.11 ENST00000423698.2
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr3_-_141747950 0.11 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_39046615 0.11 ENST00000261425.3
ENST00000508137.2
 KLHL5
 kelch-like family member 5
chr2_-_136288113 0.11 ENST00000401392.1
 ZRANB3
 zinc finger, RAN-binding domain containing 3
chr19_-_10420459 0.11 ENST00000403352.1
ENST00000403903.3
 ZGLP1
 zinc finger, GATA-like protein 1
chr7_-_75401513 0.11 ENST00000005180.4
 CCL26
 chemokine (C-C motif) ligand 26
chrX_-_154493791 0.11 ENST00000369454.3
 RAB39B
 RAB39B, member RAS oncogene family
chr10_+_72194585 0.11 ENST00000420338.2
 AC022532.1
 Uncharacterized protein
chr1_-_204135450 0.11 ENST00000272190.8
ENST00000367195.2
 REN
 renin
chr6_-_15548591 0.11 ENST00000509674.1
 DTNBP1
 dystrobrevin binding protein 1
chr10_-_115904361 0.10 ENST00000428953.1
ENST00000543782.1
 C10orf118
 chromosome 10 open reading frame 118
chr19_-_45926739 0.10 ENST00000589381.1
ENST00000591636.1
ENST00000013807.5
ENST00000592023.1
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr1_-_94586651 0.10 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr3_-_197686847 0.10 ENST00000265239.6
 IQCG
 IQ motif containing G
chr1_+_120254510 0.10 ENST00000369409.4
 PHGDH
 phosphoglycerate dehydrogenase
chr3_-_185270342 0.10 ENST00000424591.2
 LIPH
 lipase, member H
chr6_+_27775899 0.10 ENST00000358739.3
 HIST1H2AI
 histone cluster 1, H2ai
chr10_+_111967345 0.10 ENST00000332674.5
ENST00000453116.1
 MXI1
 MAX interactor 1, dimerization protein
chr9_-_28026318 0.10 ENST00000308675.3
 LINGO2
 leucine rich repeat and Ig domain containing 2
chr16_-_3350614 0.10 ENST00000268674.2
 TIGD7
 tigger transposable element derived 7
chr13_+_103459704 0.10 ENST00000602836.1
 BIVM-ERCC5
 BIVM-ERCC5 readthrough
chr5_+_135496675 0.10 ENST00000507637.1
 SMAD5
 SMAD family member 5
chrX_+_55744166 0.10 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chr9_+_82187630 0.10 ENST00000265284.6
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_+_73076432 0.10 ENST00000414192.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr6_+_26156551 0.10 ENST00000304218.3
 HIST1H1E
 histone cluster 1, H1e
chr19_-_45927622 0.10 ENST00000300853.3
ENST00000589165.1
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr12_-_95945246 0.10 ENST00000258499.3
 USP44
 ubiquitin specific peptidase 44
chr9_-_124976185 0.10 ENST00000464484.2
 LHX6
 LIM homeobox 6
chr1_-_155880672 0.09 ENST00000609492.1
ENST00000368322.3
 RIT1
 Ras-like without CAAX 1
chr10_+_60759378 0.09 ENST00000432535.1
 LINC00844
 long intergenic non-protein coding RNA 844
chrX_+_135252050 0.09 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chr6_+_111408698 0.09 ENST00000368851.5
 SLC16A10
 solute carrier family 16 (aromatic amino acid transporter), member 10
chr2_+_109271481 0.09 ENST00000542845.1
ENST00000393314.2
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr20_-_39928756 0.09 ENST00000432768.2
 ZHX3
 zinc fingers and homeoboxes 3
chr9_+_82187487 0.09 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_-_124976154 0.09 ENST00000482062.1
 LHX6
 LIM homeobox 6
chr12_+_12878829 0.09 ENST00000326765.6
 APOLD1
 apolipoprotein L domain containing 1
chr11_-_625163 0.09 ENST00000349570.7
 CDHR5
 cadherin-related family member 5
chr12_-_95941987 0.09 ENST00000537435.2
 USP44
 ubiquitin specific peptidase 44
chrX_+_135251783 0.09 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr4_+_170581213 0.09 ENST00000507875.1
 CLCN3
 chloride channel, voltage-sensitive 3
chr5_-_139937895 0.09 ENST00000336283.6
 SRA1
 steroid receptor RNA activator 1
chr14_+_22554680 0.09 ENST00000390451.2
 TRAV23DV6
 T cell receptor alpha variable 23/delta variable 6
chr2_+_220143989 0.09 ENST00000336576.5
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr5_-_36301984 0.09 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
 RANBP3L
 RAN binding protein 3-like
chrX_-_15332665 0.09 ENST00000537676.1
ENST00000344384.4
 ASB11
 ankyrin repeat and SOCS box containing 11
chr7_-_38394118 0.09 ENST00000390345.2
 TRGV4
 T cell receptor gamma variable 4
chr7_-_105517021 0.09 ENST00000318724.4
ENST00000419735.3
 ATXN7L1
 ataxin 7-like 1
chrX_+_135570046 0.09 ENST00000370648.3
 BRS3
 bombesin-like receptor 3
chr9_+_82188077 0.09 ENST00000425506.1
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_+_41549105 0.08 ENST00000560965.1
 CHP1
 calcineurin-like EF-hand protein 1
chr3_+_157827841 0.08 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
 RSRC1
 arginine/serine-rich coiled-coil 1
chr7_-_14942944 0.08 ENST00000403951.2
 DGKB
 diacylglycerol kinase, beta 90kDa
chrX_+_78200829 0.08 ENST00000544091.1
 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
chr21_-_35016231 0.08 ENST00000438788.1
 CRYZL1
 crystallin, zeta (quinone reductase)-like 1
chr3_-_164796269 0.08 ENST00000264382.3
 SI
 sucrase-isomaltase (alpha-glucosidase)
chr6_-_27782548 0.08 ENST00000333151.3
 HIST1H2AJ
 histone cluster 1, H2aj
chr1_-_95391315 0.08 ENST00000545882.1
ENST00000415017.1
 CNN3
 calponin 3, acidic
chr10_+_135160844 0.08 ENST00000423766.1
ENST00000458230.1
 PRAP1
 proline-rich acidic protein 1
chr6_+_88032299 0.08 ENST00000608353.1
ENST00000392863.1
ENST00000229570.5
ENST00000608525.1
ENST00000608868.1
 SMIM8
 small integral membrane protein 8
chr3_-_57326704 0.08 ENST00000487349.1
ENST00000389601.3
 ASB14
 ankyrin repeat and SOCS box containing 14
chr8_+_107738240 0.08 ENST00000449762.2
ENST00000297447.6
 OXR1
 oxidation resistance 1
chr10_+_52152766 0.08 ENST00000596442.1
 AC069547.2
 Uncharacterized protein
chr1_-_154909329 0.08 ENST00000368467.3
 PMVK
 phosphomevalonate kinase
chr1_+_6640108 0.08 ENST00000377674.4
ENST00000488936.1
 ZBTB48
 zinc finger and BTB domain containing 48
chr8_+_26247878 0.08 ENST00000518611.1
 BNIP3L
 BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr9_-_134145880 0.08 ENST00000372269.3
ENST00000464831.1
 FAM78A
 family with sequence similarity 78, member A
chr20_+_61569463 0.08 ENST00000266069.3
 GID8
 GID complex subunit 8
chr16_+_86612112 0.08 ENST00000320241.3
 FOXL1
 forkhead box L1
chr7_+_134464376 0.08 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr8_-_7220490 0.08 ENST00000400078.2
 ZNF705G
 zinc finger protein 705G
chr8_+_52730143 0.08 ENST00000415643.1
 AC090186.1
 Uncharacterized protein
chrX_+_55744228 0.08 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr11_-_796197 0.08 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
 SLC25A22
 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_-_68052694 0.08 ENST00000457448.1
 AC010987.6
 AC010987.6
chr4_-_156787425 0.08 ENST00000537611.2
 ASIC5
 acid-sensing (proton-gated) ion channel family member 5
chr18_+_32556892 0.08 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
chr7_+_40174565 0.08 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
 C7orf10
 succinylCoA:glutarate-CoA transferase
chr2_+_220144052 0.07 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.2 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of norepinephrine secretion(GO:0010701) positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.0 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.0 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling