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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for HSF1

Z-value: 2.04

Motif logo

Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.6 HSF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg19_v2_chr8_+_145515263_1455152990.255.5e-01Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_51504411 2.12 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr19_-_51522955 2.08 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr19_-_36004543 1.98 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr2_+_102624977 1.80 ENST00000441002.1
IL1R2
interleukin 1 receptor, type II
chr1_+_35247859 1.73 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr19_-_6720686 1.69 ENST00000245907.6
C3
complement component 3
chr2_+_47596287 1.64 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr18_+_21452964 1.62 ENST00000587184.1
LAMA3
laminin, alpha 3
chr18_+_21452804 1.56 ENST00000269217.6
LAMA3
laminin, alpha 3
chr6_+_47666275 1.48 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr19_+_751122 1.45 ENST00000215582.6
MISP
mitotic spindle positioning
chr17_-_39677971 1.38 ENST00000393976.2
KRT15
keratin 15
chr6_-_136788001 1.33 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr19_-_51456198 1.32 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr1_-_153363452 1.32 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr19_-_51523412 1.30 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr19_-_51523275 1.21 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr8_+_124194752 1.20 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr19_-_51456344 1.18 ENST00000336334.3
ENST00000593428.1
KLK5
kallikrein-related peptidase 5
chr20_+_43803517 1.17 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr1_+_28261621 1.11 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_+_10471836 1.11 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr1_+_28261492 1.09 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr12_-_52911718 1.09 ENST00000548409.1
KRT5
keratin 5
chr1_+_152957707 1.08 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr1_+_15256230 1.03 ENST00000376028.4
ENST00000400798.2
KAZN
kazrin, periplakin interacting protein
chr10_-_116444371 1.01 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr2_-_238499303 1.00 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr1_+_43996518 0.99 ENST00000359947.4
ENST00000438120.1
PTPRF
protein tyrosine phosphatase, receptor type, F
chr19_-_49567124 0.93 ENST00000301411.3
NTF4
neurotrophin 4
chr2_-_238499131 0.90 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr15_-_72490114 0.89 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr17_-_3595181 0.88 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_+_220960033 0.82 ENST00000366910.5
MARC1
mitochondrial amidoxime reducing component 1
chr6_-_170599561 0.76 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr17_-_39928106 0.75 ENST00000540235.1
JUP
junction plakoglobin
chr2_+_85360499 0.72 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr7_-_139763521 0.70 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr1_-_24469602 0.69 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr20_+_61287711 0.68 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr17_-_76123101 0.67 ENST00000392467.3
TMC6
transmembrane channel-like 6
chr17_-_39661849 0.65 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr1_-_147232669 0.63 ENST00000369237.1
GJA5
gap junction protein, alpha 5, 40kDa
chr11_-_88070896 0.63 ENST00000529974.1
ENST00000527018.1
CTSC
cathepsin C
chr19_-_55660561 0.62 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr20_+_1875378 0.57 ENST00000356025.3
SIRPA
signal-regulatory protein alpha
chr20_+_1875110 0.57 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr16_-_85784557 0.57 ENST00000602675.1
C16orf74
chromosome 16 open reading frame 74
chr3_+_124223586 0.56 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr19_+_49055332 0.56 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chrX_+_147062844 0.56 ENST00000370467.3
FMR1NB
fragile X mental retardation 1 neighbor
chr4_+_76481258 0.55 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr1_+_28261533 0.54 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr20_-_18038521 0.53 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr6_+_35265586 0.52 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr6_-_32784687 0.51 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr6_-_33041378 0.50 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr3_+_130612803 0.50 ENST00000510168.1
ENST00000508532.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr11_+_59480899 0.49 ENST00000300150.7
STX3
syntaxin 3
chr8_-_81083890 0.49 ENST00000518937.1
TPD52
tumor protein D52
chr12_+_115800817 0.47 ENST00000547948.1
RP11-116D17.1
HCG2038717; Uncharacterized protein
chr8_+_8559406 0.47 ENST00000519106.1
CLDN23
claudin 23
chr1_+_156117149 0.46 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_+_470288 0.45 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr20_+_10015678 0.45 ENST00000378392.1
ENST00000378380.3
ANKEF1
ankyrin repeat and EF-hand domain containing 1
chr11_+_33563821 0.43 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chrX_-_100662881 0.43 ENST00000218516.3
GLA
galactosidase, alpha
chr7_+_130020932 0.43 ENST00000484324.1
CPA1
carboxypeptidase A1 (pancreatic)
chr15_+_75491213 0.42 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr3_+_130613001 0.42 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr14_+_96722539 0.42 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr8_-_81083341 0.42 ENST00000519303.2
TPD52
tumor protein D52
chr19_+_1065922 0.41 ENST00000539243.2
HMHA1
histocompatibility (minor) HA-1
chrX_-_15683147 0.41 ENST00000380342.3
TMEM27
transmembrane protein 27
chr5_-_172036436 0.40 ENST00000601856.1
AC027309.1
AC027309.1
chr8_-_81083731 0.40 ENST00000379096.5
TPD52
tumor protein D52
chrX_-_152989531 0.40 ENST00000458587.2
ENST00000416815.1
BCAP31
B-cell receptor-associated protein 31
chr12_+_2904102 0.40 ENST00000001008.4
FKBP4
FK506 binding protein 4, 59kDa
chr19_-_55672037 0.39 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr2_-_96701722 0.39 ENST00000434632.1
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr5_-_175964366 0.39 ENST00000274811.4
RNF44
ring finger protein 44
chr4_-_48908737 0.38 ENST00000381464.2
OCIAD2
OCIA domain containing 2
chr19_+_8117881 0.38 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr4_-_25865159 0.38 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_+_113735575 0.38 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr8_-_56685859 0.38 ENST00000523423.1
ENST00000523073.1
ENST00000519784.1
ENST00000434581.2
ENST00000519780.1
ENST00000521229.1
ENST00000522576.1
ENST00000523180.1
ENST00000522090.1
TMEM68
transmembrane protein 68
chrX_-_152989798 0.38 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr1_+_212782012 0.38 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr2_+_231577532 0.36 ENST00000258418.5
CAB39
calcium binding protein 39
chr1_-_10856694 0.36 ENST00000377022.3
ENST00000344008.5
CASZ1
castor zinc finger 1
chrX_+_30233668 0.36 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr11_-_89956227 0.36 ENST00000457199.2
ENST00000530765.1
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr19_-_17445613 0.36 ENST00000159087.4
ANO8
anoctamin 8
chr4_-_48908822 0.36 ENST00000508632.1
OCIAD2
OCIA domain containing 2
chr4_-_48908805 0.35 ENST00000273860.4
OCIAD2
OCIA domain containing 2
chr7_+_141478242 0.35 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr1_+_196857144 0.35 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr11_+_112046190 0.35 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr5_+_141016969 0.34 ENST00000518856.1
RELL2
RELT-like 2
chr18_+_60382672 0.34 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr1_+_67773044 0.34 ENST00000262345.1
ENST00000371000.1
IL12RB2
interleukin 12 receptor, beta 2
chr20_+_18794370 0.34 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr1_-_247921982 0.34 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr3_-_123411191 0.34 ENST00000354792.5
ENST00000508240.1
MYLK
myosin light chain kinase
chr19_-_14629224 0.34 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr17_+_53828333 0.33 ENST00000268896.5
PCTP
phosphatidylcholine transfer protein
chr3_+_32433154 0.33 ENST00000334983.5
ENST00000349718.4
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr3_+_32433363 0.32 ENST00000465248.1
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr3_+_130613226 0.32 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr5_+_141016508 0.32 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELL2
RELT-like 2
chr12_+_50366620 0.32 ENST00000315520.5
AQP6
aquaporin 6, kidney specific
chr19_-_2051223 0.32 ENST00000309340.7
ENST00000589534.1
ENST00000250896.3
ENST00000589509.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chrX_+_49020882 0.31 ENST00000454342.1
MAGIX
MAGI family member, X-linked
chr14_+_22977587 0.31 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr2_+_109403193 0.31 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr7_+_43622664 0.31 ENST00000319357.5
STK17A
serine/threonine kinase 17a
chr19_+_8117636 0.31 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr9_+_139847347 0.31 ENST00000371632.3
LCN12
lipocalin 12
chr17_-_54911250 0.30 ENST00000575658.1
ENST00000397861.2
C17orf67
chromosome 17 open reading frame 67
chr15_+_68871308 0.30 ENST00000261861.5
CORO2B
coronin, actin binding protein, 2B
chr21_+_39644172 0.30 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_206138457 0.30 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr14_-_77787198 0.30 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr17_+_54911444 0.29 ENST00000284061.3
ENST00000572810.1
DGKE
diacylglycerol kinase, epsilon 64kDa
chr22_+_38453207 0.29 ENST00000404072.3
ENST00000424694.1
PICK1
protein interacting with PRKCA 1
chr21_+_39644214 0.29 ENST00000438657.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_173472607 0.28 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr12_+_51632666 0.28 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr17_+_53828381 0.28 ENST00000576183.1
PCTP
phosphatidylcholine transfer protein
chr4_+_41937131 0.28 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr6_-_105627735 0.28 ENST00000254765.3
POPDC3
popeye domain containing 3
chr18_-_19284724 0.28 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr16_+_85942594 0.28 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr11_-_89956461 0.28 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr2_-_9143786 0.27 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr17_-_62208169 0.27 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr11_-_47869865 0.27 ENST00000530326.1
ENST00000532747.1
NUP160
nucleoporin 160kDa
chr6_+_31795506 0.27 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr1_+_110577229 0.27 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr1_+_196743912 0.27 ENST00000367425.4
CFHR3
complement factor H-related 3
chr1_+_212738676 0.27 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr11_+_93861993 0.27 ENST00000227638.3
ENST00000436171.2
PANX1
pannexin 1
chr1_+_120839005 0.27 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr11_-_104840093 0.27 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr22_+_38453378 0.26 ENST00000437453.1
ENST00000356976.3
PICK1
protein interacting with PRKCA 1
chr7_-_3083573 0.26 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr9_-_34372830 0.26 ENST00000379142.3
KIAA1161
KIAA1161
chr22_+_48972118 0.26 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_+_69061594 0.26 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr3_+_130569429 0.26 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr22_-_42526802 0.25 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
chr14_+_39734482 0.25 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5
CTAGE family, member 5
chr10_-_125851961 0.25 ENST00000346248.5
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr17_+_7258442 0.25 ENST00000389982.4
ENST00000576060.1
ENST00000330767.4
TMEM95
transmembrane protein 95
chr2_+_11674213 0.25 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chrX_-_154563889 0.25 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr11_-_47870019 0.25 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr19_+_58038683 0.25 ENST00000240719.3
ENST00000376233.3
ENST00000594943.1
ENST00000602149.1
ZNF549
zinc finger protein 549
chr12_+_66696322 0.25 ENST00000247815.4
HELB
helicase (DNA) B
chr16_-_57831914 0.25 ENST00000421376.2
KIFC3
kinesin family member C3
chr1_+_196743943 0.24 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr6_+_73331520 0.24 ENST00000342056.2
ENST00000355194.4
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr21_-_43346790 0.24 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr19_-_54876558 0.24 ENST00000391742.2
ENST00000434277.2
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr17_+_56315936 0.24 ENST00000543544.1
LPO
lactoperoxidase
chr19_+_39421556 0.24 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr3_+_130569592 0.24 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr6_-_167369612 0.23 ENST00000507747.1
RP11-514O12.4
RP11-514O12.4
chr21_+_42733870 0.23 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr19_-_16653226 0.23 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr3_-_59035673 0.23 ENST00000491845.1
ENST00000472469.1
ENST00000471288.1
ENST00000295966.7
C3orf67
chromosome 3 open reading frame 67
chr2_+_173420697 0.23 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr7_-_150780487 0.23 ENST00000482202.1
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr17_+_40714092 0.23 ENST00000420359.1
ENST00000449624.1
ENST00000585811.1
ENST00000585909.1
ENST00000586771.1
ENST00000421097.2
ENST00000591779.1
ENST00000587858.1
ENST00000587214.1
ENST00000587157.1
ENST00000590958.1
ENST00000393818.2
COASY
CoA synthase
chr6_+_4890226 0.22 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chr20_+_55904815 0.22 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11
SPO11 meiotic protein covalently bound to DSB
chr7_-_111032971 0.22 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_-_14117074 0.22 ENST00000588885.1
ENST00000254325.4
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr3_-_183735731 0.22 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr16_-_12184159 0.22 ENST00000312019.2
RP11-276H1.3
RP11-276H1.3
chr19_-_16653325 0.22 ENST00000546361.2
CHERP
calcium homeostasis endoplasmic reticulum protein
chr1_-_143913143 0.22 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chrX_-_72434628 0.21 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr6_+_31465849 0.21 ENST00000399150.3
MICB
MHC class I polypeptide-related sequence B
chr19_-_10628117 0.21 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr6_-_46620522 0.21 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr9_-_86955598 0.21 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr1_+_111415757 0.21 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr17_-_17485731 0.21 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr19_+_45349630 0.21 ENST00000252483.5
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr15_-_83378611 0.21 ENST00000542200.1
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr9_+_74764278 0.21 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr3_+_44916098 0.21 ENST00000296125.4
TGM4
transglutaminase 4
chr12_+_70132632 0.21 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3IP
RAB3A interacting protein
chr15_+_34394257 0.21 ENST00000397766.2
PGBD4
piggyBac transposable element derived 4
chr17_-_56350797 0.21 ENST00000577220.1
MPO
myeloperoxidase
chr12_+_133287392 0.21 ENST00000317555.2
ENST00000498926.2
PGAM5
phosphoglycerate mutase family member 5
chr1_+_166958497 0.20 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr11_+_34645791 0.20 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
EHF
ets homologous factor
chr22_-_26961328 0.20 ENST00000398110.2
TPST2
tyrosylprotein sulfotransferase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.5 1.8 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.4 2.5 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 1.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 2.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 1.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 2.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 1.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 0.3 GO:0090346 cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.3 0.8 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 0.9 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.6 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 2.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.6 GO:0010652 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.2 1.1 GO:0006196 AMP catabolic process(GO:0006196)
0.2 0.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 1.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 0.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.2 GO:0090288 negative regulation of cellular response to growth factor stimulus(GO:0090288)
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 4.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.7 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.4 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.8 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.1 1.3 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.5 GO:0060214 endocardium formation(GO:0060214)
0.1 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.6 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.2 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.2 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.2 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 0.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.3 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.5 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 1.2 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.3 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0061589 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.6 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 3.2 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:1901536 negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.0 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.0 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 GO:0005610 laminin-5 complex(GO:0005610)
0.4 2.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.8 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 2.4 GO:0005922 connexon complex(GO:0005922)
0.1 0.7 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.1 0.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 3.3 GO:0001533 cornified envelope(GO:0001533)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 2.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 2.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 2.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 1.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 2.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 0.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.8 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 0.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 2.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 1.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.6 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 3.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0001032 RNA polymerase III transcription factor binding(GO:0001025) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 9.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 1.0 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0019239 deaminase activity(GO:0019239)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 4.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors