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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for IRF3

Z-value: 1.08

Motif logo

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Transcription factors associated with IRF3

Gene Symbol Gene ID Gene Info
IRF3
ENSG00000126456.11 IRF3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF3hg19_v2_chr19_-_50168861_50168873-0.782.2e-02Click!

Activity profile of IRF3 motif

Sorted Z-values of IRF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_95158644 1.11 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr1_+_221054584 1.10 ENST00000549319.1
 HLX
 H2.0-like homeobox
chr5_-_95158375 1.05 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX
 glutaredoxin (thioltransferase)
chr2_-_190044480 0.84 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr1_+_79115503 0.82 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44
 interferon-induced protein 44
chr10_+_91087651 0.82 ENST00000371818.4
 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
chr7_-_92777606 0.79 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
 SAMD9L
 sterile alpha motif domain containing 9-like
chr10_+_91092241 0.74 ENST00000371811.4
 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
chr6_+_72922590 0.72 ENST00000523963.1
 RIMS1
 regulating synaptic membrane exocytosis 1
chr11_-_57335280 0.72 ENST00000287156.4
 UBE2L6
 ubiquitin-conjugating enzyme E2L 6
chr4_+_124320665 0.71 ENST00000394339.2
 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr6_+_72922505 0.71 ENST00000401910.3
 RIMS1
 regulating synaptic membrane exocytosis 1
chr10_-_49701686 0.70 ENST00000417247.2
 ARHGAP22
 Rho GTPase activating protein 22
chr1_+_948803 0.64 ENST00000379389.4
 ISG15
 ISG15 ubiquitin-like modifier
chr3_-_122283079 0.59 ENST00000471785.1
ENST00000466126.1
 PARP9
 poly (ADP-ribose) polymerase family, member 9
chr3_-_122283424 0.57 ENST00000477522.2
ENST00000360356.2
 PARP9
 poly (ADP-ribose) polymerase family, member 9
chrX_+_80457442 0.57 ENST00000373212.5
 SH3BGRL
 SH3 domain binding glutamic acid-rich protein like
chr7_-_122526799 0.52 ENST00000334010.7
ENST00000313070.7
 CADPS2
 Ca++-dependent secretion activator 2
chr2_-_145275228 0.50 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr19_+_49977466 0.49 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
 FLT3LG
 fms-related tyrosine kinase 3 ligand
chr1_+_210502238 0.49 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
 HHAT
 hedgehog acyltransferase
chr17_+_6659153 0.48 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
 XAF1
 XIAP associated factor 1
chr2_+_201980827 0.46 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr2_+_201980961 0.46 ENST00000342795.5
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr12_+_133614119 0.46 ENST00000327668.7
 ZNF84
 zinc finger protein 84
chr19_-_17516449 0.45 ENST00000252593.6
 BST2
 bone marrow stromal cell antigen 2
chr12_+_133613878 0.44 ENST00000392319.2
ENST00000543758.1
 ZNF84
 zinc finger protein 84
chr19_+_49977818 0.44 ENST00000594009.1
ENST00000595510.1
 FLT3LG
 fms-related tyrosine kinase 3 ligand
chr4_-_156875003 0.43 ENST00000433477.3
 CTSO
 cathepsin O
chr6_-_3752222 0.42 ENST00000380283.4
 PXDC1
 PX domain containing 1
chr20_-_47894569 0.42 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
 ZNFX1
 zinc finger, NFX1-type containing 1
chr10_+_92980517 0.41 ENST00000336126.5
 PCGF5
 polycomb group ring finger 5
chr14_+_24605389 0.40 ENST00000382708.3
ENST00000561435.1
 PSME1
 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr19_+_10196781 0.39 ENST00000253110.11
 C19orf66
 chromosome 19 open reading frame 66
chr16_-_67970990 0.38 ENST00000358514.4
 PSMB10
 proteasome (prosome, macropain) subunit, beta type, 10
chr6_+_32821924 0.38 ENST00000374859.2
ENST00000453265.2
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr1_-_146644036 0.38 ENST00000425272.2
 PRKAB2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr12_-_4758159 0.36 ENST00000545990.2
 AKAP3
 A kinase (PRKA) anchor protein 3
chr3_+_187086120 0.36 ENST00000259030.2
 RTP4
 receptor (chemosensory) transporter protein 4
chr20_+_388791 0.35 ENST00000441733.1
ENST00000353660.3
 RBCK1
 RanBP-type and C3HC4-type zinc finger containing 1
chr7_+_100728720 0.35 ENST00000306085.6
ENST00000412507.1
 TRIM56
 tripartite motif containing 56
chr20_-_33872518 0.35 ENST00000374436.3
 EIF6
 eukaryotic translation initiation factor 6
chr2_+_201981527 0.34 ENST00000441224.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr9_+_95087766 0.33 ENST00000375587.3
 CENPP
 centromere protein P
chr20_-_33872548 0.32 ENST00000374443.3
 EIF6
 eukaryotic translation initiation factor 6
chr19_+_39786962 0.32 ENST00000333625.2
 IFNL1
 interferon, lambda 1
chr2_-_119605253 0.30 ENST00000295206.6
 EN1
 engrailed homeobox 1
chr5_+_140749803 0.30 ENST00000576222.1
 PCDHGB3
 protocadherin gamma subfamily B, 3
chr12_+_133613937 0.30 ENST00000539354.1
ENST00000542874.1
ENST00000438628.2
 ZNF84
 zinc finger protein 84
chr10_-_14996321 0.30 ENST00000378289.4
 DCLRE1C
 DNA cross-link repair 1C
chr19_+_10196981 0.29 ENST00000591813.1
 C19orf66
 chromosome 19 open reading frame 66
chr7_+_142829162 0.28 ENST00000291009.3
 PIP
 prolactin-induced protein
chr6_+_3068606 0.28 ENST00000259808.4
 RIPK1
 receptor (TNFRSF)-interacting serine-threonine kinase 1
chr10_+_35415978 0.28 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
 CREM
 cAMP responsive element modulator
chr5_-_180288248 0.27 ENST00000512132.1
ENST00000506439.1
ENST00000502412.1
ENST00000359141.6
 ZFP62
 ZFP62 zinc finger protein
chr4_-_77134742 0.27 ENST00000452464.2
 SCARB2
 scavenger receptor class B, member 2
chr14_+_24605361 0.26 ENST00000206451.6
ENST00000559123.1
 PSME1
 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr10_+_91061712 0.26 ENST00000371826.3
 IFIT2
 interferon-induced protein with tetratricopeptide repeats 2
chr4_-_74847800 0.26 ENST00000296029.3
 PF4
 platelet factor 4
chr1_+_145292806 0.25 ENST00000448873.2
 NBPF10
 neuroblastoma breakpoint family, member 10
chr12_+_6561190 0.25 ENST00000544021.1
ENST00000266556.7
 TAPBPL
 TAP binding protein-like
chr4_-_77135046 0.25 ENST00000264896.2
 SCARB2
 scavenger receptor class B, member 2
chr10_+_115439630 0.24 ENST00000369318.3
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr6_+_26440700 0.24 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
 BTN3A3
 butyrophilin, subfamily 3, member A3
chr15_-_62352570 0.24 ENST00000261517.5
ENST00000395896.4
ENST00000395898.3
 VPS13C
 vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr1_+_159931002 0.24 ENST00000443364.1
ENST00000423943.1
 RP11-48O20.4
 long intergenic non-protein coding RNA 1133
chr2_-_152118352 0.23 ENST00000331426.5
 RBM43
 RNA binding motif protein 43
chr2_-_231084617 0.23 ENST00000409815.2
 SP110
 SP110 nuclear body protein
chr22_-_36556821 0.23 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
 APOL3
 apolipoprotein L, 3
chr19_+_17516531 0.23 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
 MVB12A
CTD-2521M24.9
 multivesicular body subunit 12A
CTD-2521M24.9
chr10_+_115439282 0.23 ENST00000369321.2
ENST00000345633.4
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr1_+_151129135 0.22 ENST00000602841.1
 SCNM1
 sodium channel modifier 1
chr6_-_110964453 0.22 ENST00000413605.2
 CDK19
 cyclin-dependent kinase 19
chr8_-_67525473 0.22 ENST00000522677.3
 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
chr11_-_615570 0.22 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
 IRF7
 interferon regulatory factor 7
chr7_-_138794081 0.22 ENST00000464606.1
 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
chr14_-_70883708 0.21 ENST00000256366.4
 SYNJ2BP
 synaptojanin 2 binding protein
chr10_+_115439699 0.21 ENST00000369315.1
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr14_+_73525265 0.20 ENST00000525161.1
 RBM25
 RNA binding motif protein 25
chr10_-_102046417 0.20 ENST00000370372.2
 BLOC1S2
 biogenesis of lysosomal organelles complex-1, subunit 2
chr17_-_40264692 0.20 ENST00000591220.1
ENST00000251642.3
 DHX58
 DEXH (Asp-Glu-X-His) box polypeptide 58
chr1_-_182558374 0.20 ENST00000367559.3
ENST00000539397.1
 RNASEL
 ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr22_-_36635684 0.20 ENST00000358502.5
 APOL2
 apolipoprotein L, 2
chr2_+_69240302 0.20 ENST00000303714.4
 ANTXR1
 anthrax toxin receptor 1
chr10_-_22292675 0.19 ENST00000376946.1
 DNAJC1
 DnaJ (Hsp40) homolog, subfamily C, member 1
chr22_+_36649056 0.19 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
 APOL1
 apolipoprotein L, 1
chr10_-_102046098 0.19 ENST00000441611.1
 BLOC1S2
 biogenesis of lysosomal organelles complex-1, subunit 2
chr2_-_231084820 0.18 ENST00000258382.5
ENST00000338556.3
 SP110
 SP110 nuclear body protein
chrX_-_48937531 0.17 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
 WDR45
AF196779.12
 WD repeat domain 45
WD repeat domain phosphoinositide-interacting protein 4
chr2_+_201981119 0.17 ENST00000395148.2
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr2_+_113672770 0.17 ENST00000311328.2
 IL37
 interleukin 37
chr14_-_20881579 0.16 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
 TEP1
 telomerase-associated protein 1
chr2_+_239756671 0.16 ENST00000448943.2
 TWIST2
 twist family bHLH transcription factor 2
chr1_-_161039753 0.16 ENST00000368015.1
 ARHGAP30
 Rho GTPase activating protein 30
chr1_-_177939348 0.15 ENST00000464631.2
 SEC16B
 SEC16 homolog B (S. cerevisiae)
chr1_+_25599018 0.15 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
 RHD
 Rh blood group, D antigen
chr15_+_64428529 0.15 ENST00000560861.1
 SNX1
 sorting nexin 1
chr7_-_92747269 0.15 ENST00000446617.1
ENST00000379958.2
 SAMD9
 sterile alpha motif domain containing 9
chrX_+_77154935 0.15 ENST00000481445.1
 COX7B
 cytochrome c oxidase subunit VIIb
chr5_+_140071178 0.14 ENST00000508522.1
ENST00000448069.2
 HARS2
 histidyl-tRNA synthetase 2, mitochondrial
chr6_-_28226984 0.14 ENST00000423974.2
 ZKSCAN4
 zinc finger with KRAB and SCAN domains 4
chr2_-_175629135 0.14 ENST00000409542.1
ENST00000409219.1
 CHRNA1
 cholinergic receptor, nicotinic, alpha 1 (muscle)
chr1_-_161039647 0.14 ENST00000368013.3
 ARHGAP30
 Rho GTPase activating protein 30
chr5_-_77656175 0.14 ENST00000513755.1
ENST00000421004.3
 CTD-2037K23.2
 CTD-2037K23.2
chr16_+_75681650 0.14 ENST00000300086.4
 TERF2IP
 telomeric repeat binding factor 2, interacting protein
chr19_+_50431959 0.14 ENST00000595125.1
 ATF5
 activating transcription factor 5
chr3_+_122399444 0.13 ENST00000474629.2
 PARP14
 poly (ADP-ribose) polymerase family, member 14
chr2_+_219125714 0.13 ENST00000522678.1
ENST00000519574.1
ENST00000521462.1
 GPBAR1
 G protein-coupled bile acid receptor 1
chr6_-_36355513 0.13 ENST00000340181.4
ENST00000373737.4
 ETV7
 ets variant 7
chr20_-_20033052 0.12 ENST00000536226.1
 CRNKL1
 crooked neck pre-mRNA splicing factor 1
chr3_+_184529929 0.12 ENST00000287546.4
ENST00000437079.3
 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
chr17_-_63052929 0.12 ENST00000439174.2
 GNA13
 guanine nucleotide binding protein (G protein), alpha 13
chr20_+_61436146 0.12 ENST00000290291.6
 OGFR
 opioid growth factor receptor
chr1_+_236557569 0.12 ENST00000334232.4
 EDARADD
 EDAR-associated death domain
chr3_+_184529948 0.12 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
chr2_-_231084659 0.12 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
 SP110
 SP110 nuclear body protein
chr10_+_35416223 0.12 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
 CREM
 cAMP responsive element modulator
chr6_-_121655593 0.12 ENST00000398212.2
 TBC1D32
 TBC1 domain family, member 32
chr1_+_150480551 0.12 ENST00000369049.4
ENST00000369047.4
 ECM1
 extracellular matrix protein 1
chr1_+_151129103 0.12 ENST00000368910.3
 TNFAIP8L2
 tumor necrosis factor, alpha-induced protein 8-like 2
chr1_-_146644122 0.11 ENST00000254101.3
 PRKAB2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr12_+_129028500 0.11 ENST00000315208.8
 TMEM132C
 transmembrane protein 132C
chr16_+_66968343 0.11 ENST00000417689.1
ENST00000561697.1
ENST00000317091.4
ENST00000566182.1
 CES2
 carboxylesterase 2
chr7_-_138794394 0.10 ENST00000242351.5
ENST00000471652.1
 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
chr1_+_150480576 0.10 ENST00000346569.6
 ECM1
 extracellular matrix protein 1
chr14_-_24615805 0.10 ENST00000560410.1
 PSME2
 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr22_+_18632666 0.10 ENST00000215794.7
 USP18
 ubiquitin specific peptidase 18
chr6_+_28193037 0.10 ENST00000531981.1
ENST00000425468.2
ENST00000252207.5
ENST00000531979.1
ENST00000527436.1
 ZSCAN9
 zinc finger and SCAN domain containing 9
chr10_-_135187193 0.09 ENST00000368547.3
 ECHS1
 enoyl CoA hydratase, short chain, 1, mitochondrial
chr14_-_24615523 0.08 ENST00000559056.1
 PSME2
 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr14_+_35452104 0.08 ENST00000216774.6
ENST00000546080.1
 SRP54
 signal recognition particle 54kDa
chr6_+_31540056 0.07 ENST00000418386.2
 LTA
 lymphotoxin alpha
chr14_+_35452169 0.07 ENST00000555557.1
 SRP54
 signal recognition particle 54kDa
chr9_-_140082983 0.07 ENST00000323927.2
 ANAPC2
 anaphase promoting complex subunit 2
chr6_+_42018614 0.07 ENST00000465926.1
ENST00000482432.1
 TAF8
 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr12_-_54582655 0.07 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
 SMUG1
 single-strand-selective monofunctional uracil-DNA glycosylase 1
chr8_+_22446763 0.06 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
 AC037459.4
 Uncharacterized protein
chr19_+_17516909 0.06 ENST00000601007.1
ENST00000594913.1
ENST00000599975.1
ENST00000600514.1
 CTD-2521M24.9
MVB12A
 CTD-2521M24.9
multivesicular body subunit 12A
chr17_+_21730180 0.06 ENST00000584398.1
 UBBP4
 ubiquitin B pseudogene 4
chrX_+_154610428 0.06 ENST00000354514.4
 H2AFB2
 H2A histone family, member B2
chr17_+_25958174 0.06 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
 LGALS9
 lectin, galactoside-binding, soluble, 9
chr20_+_388679 0.05 ENST00000356286.5
ENST00000475269.1
 RBCK1
 RanBP-type and C3HC4-type zinc finger containing 1
chr4_+_100495864 0.05 ENST00000265517.5
ENST00000422897.2
 MTTP
 microsomal triglyceride transfer protein
chr6_+_26402517 0.05 ENST00000414912.2
 BTN3A1
 butyrophilin, subfamily 3, member A1
chr14_+_77790901 0.05 ENST00000553586.1
ENST00000555583.1
 GSTZ1
 glutathione S-transferase zeta 1
chr1_-_177939041 0.05 ENST00000308284.6
 SEC16B
 SEC16 homolog B (S. cerevisiae)
chr11_-_615942 0.05 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
 IRF7
 interferon regulatory factor 7
chr22_+_31892373 0.05 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
 SFI1
 Sfi1 homolog, spindle assembly associated (yeast)
chr6_-_30181156 0.05 ENST00000418026.1
ENST00000416596.1
ENST00000453195.1
 TRIM26
 tripartite motif containing 26
chr2_+_127413704 0.05 ENST00000409836.3
 GYPC
 glycophorin C (Gerbich blood group)
chr2_-_37384175 0.04 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
 EIF2AK2
 eukaryotic translation initiation factor 2-alpha kinase 2
chr19_+_50432400 0.04 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
 ATF5
 activating transcription factor 5
chr16_-_29874462 0.04 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
 CDIPT
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chrX_+_119384607 0.04 ENST00000326624.2
ENST00000557385.1
 ZBTB33
 zinc finger and BTB domain containing 33
chr2_+_127413677 0.04 ENST00000356887.7
 GYPC
 glycophorin C (Gerbich blood group)
chr4_+_118955500 0.04 ENST00000296499.5
 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr19_+_17516624 0.04 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
 CTD-2521M24.9
 CTD-2521M24.9
chr4_+_130017268 0.04 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
 C4orf33
 chromosome 4 open reading frame 33
chr22_+_31892261 0.04 ENST00000432498.1
ENST00000540643.1
ENST00000443326.1
ENST00000414585.1
 SFI1
 Sfi1 homolog, spindle assembly associated (yeast)
chr5_-_96143796 0.04 ENST00000296754.3
 ERAP1
 endoplasmic reticulum aminopeptidase 1
chr3_+_63898275 0.04 ENST00000538065.1
 ATXN7
 ataxin 7
chr6_-_30181133 0.04 ENST00000454678.2
ENST00000434785.1
 TRIM26
 tripartite motif containing 26
chr20_+_388935 0.03 ENST00000382181.2
ENST00000400247.3
 RBCK1
 RanBP-type and C3HC4-type zinc finger containing 1
chr3_+_63897605 0.03 ENST00000487717.1
 ATXN7
 ataxin 7
chrX_+_57313113 0.03 ENST00000374900.4
 FAAH2
 fatty acid amide hydrolase 2
chr3_-_122283100 0.03 ENST00000492382.1
ENST00000462315.1
 PARP9
 poly (ADP-ribose) polymerase family, member 9
chr6_+_26402465 0.03 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
 BTN3A1
 butyrophilin, subfamily 3, member A1
chrX_+_10031499 0.02 ENST00000454666.1
 WWC3
 WWC family member 3
chr20_+_44509857 0.02 ENST00000372523.1
ENST00000372520.1
 ZSWIM1
 zinc finger, SWIM-type containing 1
chr8_+_145438870 0.02 ENST00000527931.1
 FAM203B
 family with sequence similarity 203, member B
chr16_-_29875057 0.02 ENST00000219789.6
 CDIPT
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr6_-_36355486 0.02 ENST00000538992.1
 ETV7
 ets variant 7
chr2_+_69240415 0.02 ENST00000409829.3
 ANTXR1
 anthrax toxin receptor 1
chr22_+_39436862 0.02 ENST00000381565.2
ENST00000452957.2
 APOBEC3F
APOBEC3G
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr17_+_21729899 0.02 ENST00000583708.1
 UBBP4
 ubiquitin B pseudogene 4
chr9_+_140083099 0.01 ENST00000322310.5
 SSNA1
 Sjogren syndrome nuclear autoantigen 1
chr2_-_175629164 0.01 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
 CHRNA1
 cholinergic receptor, nicotinic, alpha 1 (muscle)
chr12_-_127256772 0.01 ENST00000536517.1
 LINC00944
 long intergenic non-protein coding RNA 944
chr19_+_17516494 0.01 ENST00000534306.1
 CTD-2521M24.9
 CTD-2521M24.9
chr2_+_99771418 0.01 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
 LIPT1
MRPL30
 lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr3_+_122283064 0.01 ENST00000296161.4
 DTX3L
 deltex 3-like (Drosophila)
chr1_-_89664595 0.01 ENST00000355754.6
 GBP4
 guanylate binding protein 4
chrX_+_52920336 0.00 ENST00000452154.2
 FAM156B
 family with sequence similarity 156, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.2 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.2 0.7 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 0.5 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 1.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 1.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 2.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.3 GO:0019075 virus maturation(GO:0019075)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0032831 natural killer cell tolerance induction(GO:0002519) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 1.6 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.5 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.3 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.7 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.6 GO:0031386 protein tag(GO:0031386)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0016409 palmitoyltransferase activity(GO:0016409)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling