Project

Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

Navigation
Downloads

Results for IRF9

Z-value: 1.13

Motif logo

Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
ENSG00000213928.4 IRF9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF9hg19_v2_chr14_+_24630465_246305310.724.5e-02Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr1_+_79086088 2.54 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr6_+_72922590 1.16 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72922505 1.16 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_162602244 1.00 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr18_-_25616519 0.94 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr13_-_43566301 0.94 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr17_+_6659153 0.82 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr1_+_79115503 0.79 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr5_+_32710736 0.65 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_-_57335280 0.60 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr14_+_24630465 0.52 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr3_-_122283079 0.52 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr7_+_134551583 0.51 ENST00000435928.1
CALD1
caldesmon 1
chr3_-_122283424 0.49 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr10_-_25241499 0.48 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chrX_-_63005405 0.47 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr11_-_86383157 0.44 ENST00000393324.3
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr6_-_82462425 0.43 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr11_-_86383650 0.41 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr10_+_91092241 0.38 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr1_+_948803 0.37 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr6_-_24936170 0.37 ENST00000538035.1
FAM65B
family with sequence similarity 65, member B
chr15_+_91643442 0.36 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chrX_+_22056165 0.36 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr10_+_91174314 0.33 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr2_-_152146385 0.33 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr4_+_186990298 0.32 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr17_+_78234625 0.31 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr19_-_17516449 0.31 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr17_+_46908350 0.27 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr4_-_77134742 0.27 ENST00000452464.2
SCARB2
scavenger receptor class B, member 2
chr3_+_151986709 0.27 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr19_+_10196981 0.26 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr11_-_615570 0.26 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr10_+_115439630 0.25 ENST00000369318.3
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr16_-_15736881 0.25 ENST00000540441.2
KIAA0430
KIAA0430
chr7_+_100728720 0.25 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr16_+_28875126 0.25 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr3_+_187086120 0.24 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr10_+_115439282 0.23 ENST00000369321.2
ENST00000345633.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr14_+_100531615 0.23 ENST00000392920.3
EVL
Enah/Vasp-like
chr6_+_6588902 0.23 ENST00000230568.4
LY86
lymphocyte antigen 86
chr3_-_121379739 0.23 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr10_+_115439699 0.22 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr4_-_77135046 0.22 ENST00000264896.2
SCARB2
scavenger receptor class B, member 2
chr3_-_146262365 0.19 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chr17_-_4167142 0.19 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr3_-_146262352 0.18 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chrX_-_39956656 0.17 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chrX_-_48858630 0.17 ENST00000376425.3
ENST00000376444.3
GRIPAP1
GRIP1 associated protein 1
chr3_-_146262428 0.17 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr6_+_126240442 0.17 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chrX_-_48858667 0.16 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr2_-_152118352 0.16 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr9_-_21995300 0.16 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_+_241695424 0.16 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr13_+_50070491 0.15 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHF11
PHD finger protein 11
chr19_+_17516909 0.15 ENST00000601007.1
ENST00000594913.1
ENST00000599975.1
ENST00000600514.1
CTD-2521M24.9
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
chr3_-_28390581 0.15 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr14_-_67981870 0.15 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr3_-_146262488 0.14 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr1_+_236687881 0.14 ENST00000526634.1
LGALS8
lectin, galactoside-binding, soluble, 8
chr10_+_91061712 0.14 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr1_+_154377669 0.14 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr13_+_50070077 0.14 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr9_-_21995249 0.14 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr2_+_205410516 0.13 ENST00000406610.2
ENST00000462231.1
PARD3B
par-3 family cell polarity regulator beta
chr3_-_146262293 0.13 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr15_+_74287035 0.13 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr12_-_121476750 0.13 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121477039 0.12 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr4_+_37892682 0.12 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_-_67141090 0.12 ENST00000312438.7
CLCF1
cardiotrophin-like cytokine factor 1
chr1_-_207119738 0.12 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr22_+_18632666 0.12 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr3_-_146262637 0.12 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr20_+_11898507 0.12 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr12_+_6881678 0.12 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chr12_-_56753858 0.11 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr6_-_110736742 0.11 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr12_-_27167233 0.11 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3
transmembrane 7 superfamily member 3
chr1_+_241695670 0.10 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr19_+_17516531 0.10 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr7_+_18535893 0.09 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr1_-_182558374 0.09 ENST00000367559.3
ENST00000539397.1
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr5_-_142783175 0.08 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_38296576 0.08 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr14_-_67981916 0.08 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr3_+_122399444 0.08 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr11_-_615942 0.08 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr2_-_37384175 0.07 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr5_-_142783694 0.07 ENST00000394466.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_-_105584560 0.07 ENST00000336775.5
BVES
blood vessel epicardial substance
chr3_-_122283100 0.06 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_28390415 0.06 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr3_-_28390298 0.06 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr3_-_141747459 0.06 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_+_16254488 0.05 ENST00000588246.1
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr10_-_7513904 0.05 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr12_-_121476959 0.04 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr20_+_61436146 0.04 ENST00000290291.6
OGFR
opioid growth factor receptor
chr9_+_102668915 0.03 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr9_-_33264557 0.03 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr2_+_205410723 0.03 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
PARD3B
par-3 family cell polarity regulator beta
chr8_-_27941380 0.02 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr18_+_3262954 0.02 ENST00000584539.1
MYL12B
myosin, light chain 12B, regulatory
chr6_-_33282024 0.02 ENST00000475304.1
ENST00000489157.1
TAPBP
TAP binding protein (tapasin)
chr3_-_142166846 0.01 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr16_+_28962128 0.01 ENST00000564978.1
ENST00000320805.4
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr3_-_142166904 0.01 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr6_-_33281979 0.01 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr18_-_67624160 0.01 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr3_+_122283064 0.00 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr9_+_5510558 0.00 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 0.9 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 2.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.5 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.6 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 1.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 0.3 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.9 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.7 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.5 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 2.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.9 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation