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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for KLF1

Z-value: 3.18

Motif logo

Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
ENSG00000105610.4 KLF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg19_v2_chr19_-_12997995_129980210.511.9e-01Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_43885252 7.07 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985084 6.82 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr19_-_51522955 5.69 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr19_-_36004543 4.53 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr1_+_209602156 4.46 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr18_+_29027696 4.44 ENST00000257189.4
DSG3
desmoglein 3
chr1_+_44398943 3.48 ENST00000372359.5
ENST00000414809.3
ARTN
artemin
chr19_-_51523412 3.47 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr18_+_21452964 3.41 ENST00000587184.1
LAMA3
laminin, alpha 3
chr16_-_31147020 3.41 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr18_+_21452804 3.33 ENST00000269217.6
LAMA3
laminin, alpha 3
chr16_+_67233007 3.31 ENST00000360833.1
ENST00000393997.2
ELMO3
engulfment and cell motility 3
chr1_+_44399466 3.29 ENST00000498139.2
ENST00000491846.1
ARTN
artemin
chr19_-_51523275 3.25 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr10_+_47746929 3.18 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr6_+_150464155 3.15 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr17_-_39507064 3.14 ENST00000007735.3
KRT33A
keratin 33A
chr12_-_8815215 3.07 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr12_-_8815404 3.02 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr12_-_8815299 2.99 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr19_+_35606692 2.96 ENST00000406242.3
ENST00000454903.2
FXYD3
FXYD domain containing ion transport regulator 3
chr14_-_105635090 2.70 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr17_-_34122596 2.65 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr17_-_7493390 2.63 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr8_-_21988558 2.60 ENST00000312841.8
HR
hair growth associated
chrX_-_153151586 2.57 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM
L1 cell adhesion molecule
chr19_+_35607166 2.24 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD3
FXYD domain containing ion transport regulator 3
chr18_-_28682374 2.00 ENST00000280904.6
DSC2
desmocollin 2
chr19_+_35606777 2.00 ENST00000604404.1
ENST00000435734.2
ENST00000603181.1
FXYD3
FXYD domain containing ion transport regulator 3
chr2_+_173292301 1.98 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6
integrin, alpha 6
chr1_-_117210290 1.95 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr6_+_30850697 1.93 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_+_17721920 1.93 ENST00000295156.4
VSNL1
visinin-like 1
chr11_+_1860682 1.92 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr11_+_1860832 1.84 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr10_-_47173994 1.84 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr17_-_46507537 1.81 ENST00000336915.6
SKAP1
src kinase associated phosphoprotein 1
chr8_-_75233563 1.77 ENST00000342232.4
JPH1
junctophilin 1
chr2_+_182321925 1.73 ENST00000339307.4
ENST00000397033.2
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr12_-_85306562 1.67 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr4_+_48018781 1.63 ENST00000295461.5
NIPAL1
NIPA-like domain containing 1
chr6_+_7541808 1.63 ENST00000379802.3
DSP
desmoplakin
chr14_-_23623577 1.63 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr2_-_74667612 1.55 ENST00000305557.5
ENST00000233330.6
RTKN
rhotekin
chr2_+_85360499 1.52 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr17_-_7166500 1.51 ENST00000575313.1
ENST00000397317.4
CLDN7
claudin 7
chr2_+_173292390 1.50 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6
integrin, alpha 6
chr2_+_173292280 1.48 ENST00000264107.7
ITGA6
integrin, alpha 6
chr12_-_8815477 1.46 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr6_+_106546808 1.45 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_140345820 1.45 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr12_+_29302119 1.43 ENST00000536681.3
FAR2
fatty acyl CoA reductase 2
chr2_-_38604398 1.40 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
ATL2
atlastin GTPase 2
chr19_+_1077393 1.39 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr1_-_6526192 1.35 ENST00000377782.3
ENST00000351959.5
ENST00000356876.3
TNFRSF25
tumor necrosis factor receptor superfamily, member 25
chr1_+_224803995 1.35 ENST00000272133.3
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr12_-_85306594 1.33 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr6_-_138428613 1.32 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr11_+_1861399 1.32 ENST00000381905.3
TNNI2
troponin I type 2 (skeletal, fast)
chr5_+_89770664 1.30 ENST00000503973.1
ENST00000399107.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr11_+_394196 1.29 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr17_-_39942940 1.28 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP
junction plakoglobin
chr4_-_25865159 1.27 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr19_+_41699135 1.27 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr5_+_89770696 1.24 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr7_+_86274145 1.24 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3
glutamate receptor, metabotropic 3
chr1_+_18434240 1.14 ENST00000251296.1
IGSF21
immunoglobin superfamily, member 21
chr2_-_26205340 1.14 ENST00000264712.3
KIF3C
kinesin family member 3C
chr4_-_90756769 1.13 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr5_-_16617162 1.13 ENST00000306320.9
FAM134B
family with sequence similarity 134, member B
chr5_-_115910091 1.12 ENST00000257414.8
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_17653413 1.11 ENST00000398097.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr17_-_39661849 1.10 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr17_+_30814707 1.10 ENST00000584792.1
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_-_2614927 1.06 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr18_-_28742813 1.05 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr6_+_41606176 1.05 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr17_+_7210921 1.03 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chr6_+_142622991 1.03 ENST00000230173.6
ENST00000367608.2
GPR126
G protein-coupled receptor 126
chr8_+_21912328 1.03 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
DMTN
dematin actin binding protein
chr11_-_5248294 1.03 ENST00000335295.4
HBB
hemoglobin, beta
chr17_+_7210898 1.02 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr19_+_8117881 1.01 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr6_+_142623063 0.99 ENST00000296932.8
ENST00000367609.3
GPR126
G protein-coupled receptor 126
chr19_+_41698927 0.99 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr3_+_50192537 0.98 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr20_-_22565101 0.97 ENST00000419308.2
FOXA2
forkhead box A2
chr3_+_50192499 0.97 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr6_+_130339710 0.93 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr8_-_81083341 0.93 ENST00000519303.2
TPD52
tumor protein D52
chr6_+_33589161 0.92 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr1_+_55505184 0.90 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr8_+_80523962 0.90 ENST00000518491.1
STMN2
stathmin-like 2
chr19_+_39687596 0.89 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chrX_-_152989798 0.88 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr1_+_33207381 0.87 ENST00000401073.2
KIAA1522
KIAA1522
chr6_-_20212630 0.86 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr8_+_123793633 0.84 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr12_-_54778471 0.84 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr19_+_8117636 0.83 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr9_+_74764278 0.83 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr8_+_21911054 0.81 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr1_-_6526167 0.80 ENST00000351748.3
ENST00000348333.3
TNFRSF25
tumor necrosis factor receptor superfamily, member 25
chr17_-_39023462 0.79 ENST00000251643.4
KRT12
keratin 12
chr6_+_106534192 0.79 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr15_+_75074385 0.79 ENST00000220003.9
CSK
c-src tyrosine kinase
chr16_-_4466622 0.78 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
CORO7
coronin 7
chrX_+_69672136 0.78 ENST00000374355.3
DLG3
discs, large homolog 3 (Drosophila)
chr17_+_7210852 0.77 ENST00000576930.1
EIF5A
eukaryotic translation initiation factor 5A
chr10_+_71211212 0.76 ENST00000373290.2
TSPAN15
tetraspanin 15
chr7_+_73245193 0.76 ENST00000340958.2
CLDN4
claudin 4
chr9_-_100954910 0.73 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr1_+_33231268 0.73 ENST00000373480.1
KIAA1522
KIAA1522
chr19_+_54371114 0.73 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM
myeloid-associated differentiation marker
chr16_+_23847267 0.73 ENST00000321728.7
PRKCB
protein kinase C, beta
chr19_+_42788172 0.72 ENST00000160740.3
CIC
capicua transcriptional repressor
chr1_-_11865982 0.70 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr16_-_30125177 0.70 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr17_-_43502987 0.70 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr1_+_153747746 0.69 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr17_-_56350797 0.67 ENST00000577220.1
MPO
myeloperoxidase
chr2_-_64371546 0.66 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr20_-_50722183 0.66 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr14_-_21566731 0.65 ENST00000360947.3
ZNF219
zinc finger protein 219
chr17_+_38171681 0.64 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr7_+_142982023 0.64 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
TMEM139
transmembrane protein 139
chr2_-_166651191 0.64 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr5_-_115910630 0.62 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_102314161 0.62 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_+_38171614 0.62 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr3_+_10857885 0.61 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr9_-_34048873 0.61 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2
ubiquitin associated protein 2
chr22_-_39639021 0.60 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr1_-_111743285 0.60 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chrX_+_68835911 0.60 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr16_+_618837 0.60 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr14_-_21979428 0.59 ENST00000538267.1
ENST00000298717.4
METTL3
methyltransferase like 3
chr17_-_74023474 0.58 ENST00000301607.3
EVPL
envoplakin
chr13_+_73632897 0.58 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr14_+_24783906 0.57 ENST00000396782.2
LTB4R
leukotriene B4 receptor
chr2_+_220306745 0.56 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr2_-_220408430 0.55 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr16_+_46723552 0.55 ENST00000219097.2
ENST00000568364.2
ORC6
origin recognition complex, subunit 6
chr16_+_56225248 0.55 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr9_-_33264676 0.54 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr1_-_11866034 0.54 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr12_+_51632666 0.53 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr1_-_205744205 0.52 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr17_-_27949911 0.52 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr22_+_31477296 0.52 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN
smoothelin
chr1_-_109940550 0.51 ENST00000256637.6
SORT1
sortilin 1
chr17_-_7991021 0.51 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr1_-_94147385 0.50 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr17_+_65374075 0.50 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_63655987 0.50 ENST00000509502.2
ENST00000512060.1
MARK2
MAP/microtubule affinity-regulating kinase 2
chr19_-_44285401 0.49 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_27189631 0.49 ENST00000339276.4
SFN
stratifin
chr11_-_113345995 0.49 ENST00000355319.2
ENST00000542616.1
DRD2
dopamine receptor D2
chr1_-_205744574 0.49 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr17_-_39538550 0.49 ENST00000394001.1
KRT34
keratin 34
chr6_-_33548006 0.49 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr11_+_1074870 0.48 ENST00000441003.2
ENST00000359061.5
MUC2
mucin 2, oligomeric mucus/gel-forming
chr1_+_11866270 0.47 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr1_-_115212696 0.47 ENST00000393276.3
ENST00000393277.1
DENND2C
DENN/MADD domain containing 2C
chr18_-_48723690 0.47 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr11_+_61248583 0.47 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr1_-_39395165 0.47 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr19_-_55791431 0.47 ENST00000593263.1
ENST00000376343.3
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr15_-_76005170 0.46 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr5_+_141016508 0.45 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELL2
RELT-like 2
chr6_-_33547975 0.45 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr20_-_4804244 0.45 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr5_-_95297534 0.44 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr10_+_120967072 0.43 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr9_+_74764340 0.43 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr1_+_207494853 0.43 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chrX_+_133507389 0.42 ENST00000370800.4
PHF6
PHD finger protein 6
chr3_+_8775466 0.42 ENST00000343849.2
ENST00000397368.2
CAV3
caveolin 3
chr13_+_24553933 0.42 ENST00000424834.2
ENST00000439928.2
SPATA13
RP11-309I15.1
spermatogenesis associated 13
RP11-309I15.1
chr17_-_7518145 0.41 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chr4_+_146403912 0.41 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chrX_+_48644962 0.41 ENST00000376670.3
ENST00000376665.3
GATA1
GATA binding protein 1 (globin transcription factor 1)
chr4_-_926069 0.41 ENST00000314167.4
ENST00000502656.1
GAK
cyclin G associated kinase
chr19_-_55791540 0.41 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr22_-_29137771 0.40 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr1_+_16090914 0.40 ENST00000441801.2
FBLIM1
filamin binding LIM protein 1
chr4_-_165305086 0.39 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chrX_+_40944871 0.39 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr3_-_113465065 0.39 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr10_+_104155450 0.39 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr15_+_75074410 0.39 ENST00000439220.2
CSK
c-src tyrosine kinase
chr4_-_926161 0.38 ENST00000511163.1
GAK
cyclin G associated kinase
chr17_-_66287350 0.38 ENST00000580666.1
ENST00000583477.1
SLC16A6
solute carrier family 16, member 6
chr19_-_55791563 0.38 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr14_-_65409502 0.38 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr3_-_45838011 0.37 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr6_+_158244223 0.36 ENST00000392185.3
SNX9
sorting nexin 9
chr16_+_15068916 0.36 ENST00000455313.2
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr15_+_42131011 0.36 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr20_+_825275 0.36 ENST00000541082.1
FAM110A
family with sequence similarity 110, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.8 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.9 2.6 GO:0048627 myoblast development(GO:0048627)
0.8 4.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.7 6.8 GO:0006600 creatine metabolic process(GO:0006600)
0.6 1.3 GO:0002159 desmosome assembly(GO:0002159)
0.5 4.9 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.5 2.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.4 2.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.4 1.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.4 11.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.4 3.0 GO:0015820 leucine transport(GO:0015820) proline transmembrane transport(GO:0035524)
0.4 3.0 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 0.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.4 0.7 GO:0015824 proline transport(GO:0015824)
0.3 2.7 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.3 1.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 0.9 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 1.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.3 0.9 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.3 1.3 GO:0002934 desmosome organization(GO:0002934)
0.3 0.8 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.3 1.6 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.3 1.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.3 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 1.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 1.9 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 1.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 10.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 1.1 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 1.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.6 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.9 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.2 0.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.9 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 0.8 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.9 GO:0032808 lacrimal gland development(GO:0032808)
0.2 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.6 GO:1905176 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.6 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.5 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 0.4 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.5 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 14.2 GO:0070268 cornification(GO:0070268)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 1.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 2.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) regulation of rubidium ion transmembrane transporter activity(GO:2000686) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:1990641 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1 5.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.1 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 2.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 4.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 1.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 1.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.5 GO:0001878 response to yeast(GO:0001878)
0.1 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 1.8 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.0 1.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.6 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 1.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0003016 respiratory system process(GO:0003016)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 1.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.3 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.2 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0007613 memory(GO:0007613)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 1.0 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.5 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.8 6.7 GO:0005610 laminin-5 complex(GO:0005610)
0.4 1.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.4 10.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 13.6 GO:0030057 desmosome(GO:0030057)
0.3 0.9 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 1.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 3.0 GO:0005642 annulate lamellae(GO:0005642)
0.2 5.1 GO:0005861 troponin complex(GO:0005861)
0.2 1.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.6 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.9 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 2.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 2.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.1 5.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 7.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.4 GO:0004111 creatine kinase activity(GO:0004111)
1.0 3.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.5 4.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5 1.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.5 2.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.4 5.2 GO:0038132 neuregulin binding(GO:0038132)
0.4 1.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 1.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.4 5.1 GO:0031014 troponin T binding(GO:0031014)
0.3 0.9 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 1.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 1.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 3.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.6 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 0.6 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.2 1.0 GO:0030492 hemoglobin binding(GO:0030492)
0.2 3.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 9.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 2.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.2 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 8.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 2.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0098809 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.4 GO:0005534 galactose binding(GO:0005534)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 2.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 7.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 8.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 1.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.5 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 13.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 9.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 2.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 4.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 4.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 6.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 10.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.6 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 2.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 12.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP