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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for KLF14_SP8

Z-value: 0.42

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Transcription factors associated with KLF14_SP8

Gene Symbol Gene ID Gene Info
KLF14
ENSG00000174595.4 KLF14
SP8
ENSG00000164651.12 SP8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF14hg19_v2_chr7_-_130418888_130418888-0.413.1e-01Click!
SP8hg19_v2_chr7_-_20826504_20826526-0.344.1e-01Click!

Activity profile of KLF14_SP8 motif

Sorted Z-values of KLF14_SP8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF14_SP8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_31697563 0.72 ENST00000375789.2
ENST00000416410.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr19_+_11457232 0.65 ENST00000587531.1
 CCDC159
 coiled-coil domain containing 159
chr6_-_31697255 0.57 ENST00000436437.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chrX_+_54835493 0.52 ENST00000396224.1
 MAGED2
 melanoma antigen family D, 2
chr14_-_74551096 0.41 ENST00000350259.4
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr6_-_33285505 0.39 ENST00000431845.2
 ZBTB22
 zinc finger and BTB domain containing 22
chr6_-_31697977 0.38 ENST00000375787.2
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr15_+_72410629 0.37 ENST00000340912.4
ENST00000544171.1
 SENP8
 SUMO/sentrin specific peptidase family member 8
chr9_+_131038425 0.37 ENST00000320188.5
ENST00000608796.1
ENST00000419867.2
ENST00000418976.1
 SWI5
 SWI5 recombination repair homolog (yeast)
chr1_+_183605200 0.32 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr10_+_92980517 0.31 ENST00000336126.5
 PCGF5
 polycomb group ring finger 5
chr12_+_51632638 0.29 ENST00000549732.2
 DAZAP2
 DAZ associated protein 2
chrX_+_30671476 0.28 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
 GK
 glycerol kinase
chr5_-_81046904 0.28 ENST00000515395.1
 SSBP2
 single-stranded DNA binding protein 2
chr5_+_154238149 0.27 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr14_-_74551172 0.27 ENST00000553458.1
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr19_-_50311896 0.27 ENST00000529634.2
 FUZ
 fuzzy planar cell polarity protein
chr19_+_47778119 0.27 ENST00000552360.2
 PRR24
 proline rich 24
chrX_+_54834791 0.26 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
 MAGED2
 melanoma antigen family D, 2
chr3_+_51976338 0.26 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
 PARP3
 poly (ADP-ribose) polymerase family, member 3
chr19_+_14544099 0.25 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
 PKN1
 protein kinase N1
chr16_-_8962853 0.25 ENST00000565287.1
ENST00000311052.5
 CARHSP1
 calcium regulated heat stable protein 1, 24kDa
chr11_-_67275542 0.25 ENST00000531506.1
 CDK2AP2
 cyclin-dependent kinase 2 associated protein 2
chr16_-_46864955 0.25 ENST00000565112.1
 C16orf87
 chromosome 16 open reading frame 87
chr2_-_179315453 0.25 ENST00000432031.2
 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
chrX_-_140271249 0.25 ENST00000370526.2
 LDOC1
 leucine zipper, down-regulated in cancer 1
chr9_+_130922537 0.24 ENST00000372994.1
 C9orf16
 chromosome 9 open reading frame 16
chr15_+_63414760 0.24 ENST00000557972.1
 LACTB
 lactamase, beta
chr9_-_124976154 0.24 ENST00000482062.1
 LHX6
 LIM homeobox 6
chr5_-_81046841 0.24 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
 SSBP2
 single-stranded DNA binding protein 2
chr7_+_100199800 0.24 ENST00000223061.5
 PCOLCE
 procollagen C-endopeptidase enhancer
chr9_-_124976185 0.24 ENST00000464484.2
 LHX6
 LIM homeobox 6
chrX_-_1571810 0.23 ENST00000381333.4
 ASMTL
 acetylserotonin O-methyltransferase-like
chr12_+_51632600 0.23 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
 DAZAP2
 DAZ associated protein 2
chr12_-_76953453 0.22 ENST00000549570.1
 OSBPL8
 oxysterol binding protein-like 8
chr11_+_71791693 0.22 ENST00000289488.2
ENST00000447974.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_124609742 0.22 ENST00000284292.6
 NRGN
 neurogranin (protein kinase C substrate, RC3)
chr16_-_3074231 0.22 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
 HCFC1R1
 host cell factor C1 regulator 1 (XPO1 dependent)
chr11_+_71791359 0.22 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_46299199 0.22 ENST00000529193.1
ENST00000288400.3
 CREB3L1
 cAMP responsive element binding protein 3-like 1
chr11_+_124609823 0.21 ENST00000412681.2
 NRGN
 neurogranin (protein kinase C substrate, RC3)
chr19_+_8455200 0.21 ENST00000601897.1
ENST00000594216.1
 RAB11B
 RAB11B, member RAS oncogene family
chr6_-_30710265 0.21 ENST00000438162.1
ENST00000454845.1
 FLOT1
 flotillin 1
chr5_-_81046922 0.21 ENST00000514493.1
ENST00000320672.4
 SSBP2
 single-stranded DNA binding protein 2
chr13_+_24153488 0.21 ENST00000382258.4
ENST00000382263.3
 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
chr17_-_42277203 0.21 ENST00000587097.1
 ATXN7L3
 ataxin 7-like 3
chr19_+_50354462 0.21 ENST00000601675.1
 PTOV1
 prostate tumor overexpressed 1
chr9_-_131038214 0.20 ENST00000609374.1
 GOLGA2
 golgin A2
chr19_+_36606354 0.20 ENST00000589996.1
ENST00000591296.1
 TBCB
 tubulin folding cofactor B
chr16_+_86600857 0.20 ENST00000320354.4
 FOXC2
 forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr19_-_50143452 0.20 ENST00000246792.3
 RRAS
 related RAS viral (r-ras) oncogene homolog
chr12_-_95942613 0.20 ENST00000393091.2
 USP44
 ubiquitin specific peptidase 44
chr7_+_151038785 0.20 ENST00000413040.2
ENST00000568733.1
 NUB1
 negative regulator of ubiquitin-like proteins 1
chr16_+_3074002 0.20 ENST00000326266.8
ENST00000574549.1
ENST00000575576.1
ENST00000253952.9
 THOC6
 THO complex 6 homolog (Drosophila)
chr1_-_24194771 0.20 ENST00000374479.3
 FUCA1
 fucosidase, alpha-L- 1, tissue
chr1_-_26232522 0.20 ENST00000399728.1
 STMN1
 stathmin 1
chr2_-_179315490 0.19 ENST00000487082.1
 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
chr19_+_50354430 0.19 ENST00000599732.1
 PTOV1
 prostate tumor overexpressed 1
chr15_+_63481668 0.19 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
 RAB8B
 RAB8B, member RAS oncogene family
chr19_+_50354393 0.19 ENST00000391842.1
 PTOV1
 prostate tumor overexpressed 1
chrX_+_48660287 0.19 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
 HDAC6
 histone deacetylase 6
chrX_-_134232630 0.19 ENST00000535837.1
ENST00000433425.2
 LINC00087
 long intergenic non-protein coding RNA 87
chr6_-_37467628 0.19 ENST00000373408.3
 CCDC167
 coiled-coil domain containing 167
chr19_-_40971643 0.18 ENST00000595483.1
 BLVRB
 biliverdin reductase B (flavin reductase (NADPH))
chr10_+_13142075 0.18 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
 OPTN
 optineurin
chr5_+_154237778 0.18 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr22_-_20307532 0.18 ENST00000405465.3
ENST00000248879.3
 DGCR6L
 DiGeorge syndrome critical region gene 6-like
chr20_-_3154162 0.18 ENST00000360342.3
 LZTS3
 Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr22_-_31503490 0.18 ENST00000400299.2
 SELM
 Selenoprotein M
chr19_+_50353944 0.18 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
 PTOV1
 prostate tumor overexpressed 1
chr5_+_173315283 0.18 ENST00000265085.5
 CPEB4
 cytoplasmic polyadenylation element binding protein 4
chr11_-_68519026 0.18 ENST00000255087.5
 MTL5
 metallothionein-like 5, testis-specific (tesmin)
chr17_-_42276574 0.18 ENST00000589805.1
 ATXN7L3
 ataxin 7-like 3
chr11_+_63998198 0.18 ENST00000321460.5
 DNAJC4
 DnaJ (Hsp40) homolog, subfamily C, member 4
chr5_-_176924562 0.18 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
 PDLIM7
 PDZ and LIM domain 7 (enigma)
chr11_-_68518910 0.18 ENST00000544963.1
ENST00000443940.2
 MTL5
 metallothionein-like 5, testis-specific (tesmin)
chr11_+_77532155 0.18 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr19_-_40971667 0.17 ENST00000263368.4
 BLVRB
 biliverdin reductase B (flavin reductase (NADPH))
chr6_-_30709980 0.17 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
 FLOT1
 flotillin 1
chr5_+_154238096 0.17 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr5_+_154238042 0.17 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr22_-_41985865 0.17 ENST00000216259.7
 PMM1
 phosphomannomutase 1
chr19_-_55972936 0.17 ENST00000425675.2
ENST00000589080.1
ENST00000085068.3
 ISOC2
 isochorismatase domain containing 2
chr10_-_135171178 0.17 ENST00000368551.1
 FUOM
 fucose mutarotase
chr12_+_111843749 0.16 ENST00000341259.2
 SH2B3
 SH2B adaptor protein 3
chr17_+_79935418 0.16 ENST00000306729.7
ENST00000306739.4
 ASPSCR1
 alveolar soft part sarcoma chromosome region, candidate 1
chr16_-_8962544 0.16 ENST00000570125.1
 CARHSP1
 calcium regulated heat stable protein 1, 24kDa
chr2_+_30369859 0.16 ENST00000402003.3
 YPEL5
 yippee-like 5 (Drosophila)
chr10_-_15210666 0.16 ENST00000378165.4
 NMT2
 N-myristoyltransferase 2
chr17_-_43045439 0.16 ENST00000253407.3
 C1QL1
 complement component 1, q subcomponent-like 1
chr19_+_1269324 0.16 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
 CIRBP
 cold inducible RNA binding protein
chr19_+_39989535 0.16 ENST00000356433.5
 DLL3
 delta-like 3 (Drosophila)
chr12_+_58120044 0.16 ENST00000542466.2
 AGAP2-AS1
 AGAP2 antisense RNA 1
chr18_-_5296138 0.16 ENST00000400143.3
 ZBTB14
 zinc finger and BTB domain containing 14
chr5_+_67511524 0.16 ENST00000521381.1
ENST00000521657.1
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_+_100271446 0.16 ENST00000419828.1
ENST00000427895.1
 GNB2
 guanine nucleotide binding protein (G protein), beta polypeptide 2
chr7_+_151038850 0.16 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
 NUB1
 negative regulator of ubiquitin-like proteins 1
chr8_-_120651020 0.16 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr19_+_36606654 0.16 ENST00000588385.1
ENST00000585746.1
 TBCB
 tubulin folding cofactor B
chr1_+_155829286 0.16 ENST00000368324.4
 SYT11
 synaptotagmin XI
chr2_-_128615681 0.16 ENST00000409955.1
ENST00000272645.4
 POLR2D
 polymerase (RNA) II (DNA directed) polypeptide D
chr6_-_30710510 0.16 ENST00000376389.3
 FLOT1
 flotillin 1
chr18_+_2655849 0.16 ENST00000261598.8
 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
chr12_-_76953513 0.16 ENST00000547540.1
 OSBPL8
 oxysterol binding protein-like 8
chr15_+_72947079 0.16 ENST00000421285.3
 GOLGA6B
 golgin A6 family, member B
chr22_-_39190116 0.15 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
 SUN2
DNAL4
 Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr8_+_96146168 0.15 ENST00000519516.1
 PLEKHF2
 pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr11_+_77532233 0.15 ENST00000525409.1
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr10_+_104180580 0.15 ENST00000425536.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chrX_-_1571759 0.15 ENST00000381317.3
ENST00000416733.2
 ASMTL
 acetylserotonin O-methyltransferase-like
chr16_-_30905263 0.15 ENST00000572628.1
 BCL7C
 B-cell CLL/lymphoma 7C
chr10_+_85954377 0.15 ENST00000332904.3
ENST00000372117.3
 CDHR1
 cadherin-related family member 1
chr3_-_139396560 0.15 ENST00000514703.1
ENST00000511444.1
 NMNAT3
 nicotinamide nucleotide adenylyltransferase 3
chr6_-_130031358 0.15 ENST00000368149.2
 ARHGAP18
 Rho GTPase activating protein 18
chr2_-_110371664 0.15 ENST00000545389.1
ENST00000423520.1
 SEPT10
 septin 10
chr20_+_33464407 0.15 ENST00000253382.5
 ACSS2
 acyl-CoA synthetase short-chain family member 2
chr2_+_30369807 0.15 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
 YPEL5
 yippee-like 5 (Drosophila)
chr14_-_61116168 0.15 ENST00000247182.6
 SIX1
 SIX homeobox 1
chr19_+_11457175 0.15 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
 CCDC159
 coiled-coil domain containing 159
chr7_-_2354099 0.15 ENST00000222990.3
 SNX8
 sorting nexin 8
chr19_+_39989580 0.15 ENST00000596614.1
ENST00000205143.4
 DLL3
 delta-like 3 (Drosophila)
chr19_-_59010565 0.15 ENST00000594786.1
 SLC27A5
 solute carrier family 27 (fatty acid transporter), member 5
chr9_+_133320339 0.15 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
 ASS1
 argininosuccinate synthase 1
chr21_+_33765411 0.15 ENST00000534991.2
 C21orf119
 chromosome 21 open reading frame 119
chr11_+_107799118 0.15 ENST00000320578.2
 RAB39A
 RAB39A, member RAS oncogene family
chr5_-_93447333 0.15 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
 FAM172A
 family with sequence similarity 172, member A
chr16_-_30134524 0.15 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
 MAPK3
 mitogen-activated protein kinase 3
chr6_-_30710447 0.15 ENST00000456573.2
 FLOT1
 flotillin 1
chr16_-_3073933 0.14 ENST00000574151.1
 HCFC1R1
 host cell factor C1 regulator 1 (XPO1 dependent)
chr21_+_35445811 0.14 ENST00000399312.2
 MRPS6
 mitochondrial ribosomal protein S6
chr8_-_12612962 0.14 ENST00000398246.3
 LONRF1
 LON peptidase N-terminal domain and ring finger 1
chr8_-_93978357 0.14 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
 TRIQK
 triple QxxK/R motif containing
chr17_+_17942684 0.14 ENST00000376345.3
 GID4
 GID complex subunit 4
chr3_-_48936272 0.14 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
 SLC25A20
 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr9_+_133320301 0.14 ENST00000352480.5
 ASS1
 argininosuccinate synthase 1
chr17_-_26903900 0.14 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
 ALDOC
 aldolase C, fructose-bisphosphate
chr1_+_113933371 0.14 ENST00000369617.4
 MAGI3
 membrane associated guanylate kinase, WW and PDZ domain containing 3
chrX_-_48901012 0.14 ENST00000315869.7
 TFE3
 transcription factor binding to IGHM enhancer 3
chr17_+_66243715 0.14 ENST00000359904.3
 AMZ2
 archaelysin family metallopeptidase 2
chr19_-_10445399 0.14 ENST00000592945.1
 ICAM3
 intercellular adhesion molecule 3
chr19_+_36606933 0.14 ENST00000586868.1
 TBCB
 tubulin folding cofactor B
chr15_-_82641706 0.14 ENST00000439287.4
 GOLGA6L10
 golgin A6 family-like 10
chr19_-_36606181 0.14 ENST00000221859.4
 POLR2I
 polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr4_-_39529049 0.14 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
 UGDH
 UDP-glucose 6-dehydrogenase
chr19_-_46142637 0.14 ENST00000590043.1
ENST00000589876.1
 EML2
 echinoderm microtubule associated protein like 2
chr11_-_64052111 0.14 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
 BAD
 BCL2-associated agonist of cell death
chrX_-_48815633 0.14 ENST00000428668.2
 OTUD5
 OTU domain containing 5
chr1_-_110283138 0.14 ENST00000256594.3
 GSTM3
 glutathione S-transferase mu 3 (brain)
chr12_+_6833237 0.13 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
 COPS7A
 COP9 signalosome subunit 7A
chrX_-_48755030 0.13 ENST00000490755.2
ENST00000465150.2
ENST00000495490.2
 TIMM17B
 translocase of inner mitochondrial membrane 17 homolog B (yeast)
chr7_+_100209979 0.13 ENST00000493970.1
ENST00000379527.2
 MOSPD3
 motile sperm domain containing 3
chr7_+_100209725 0.13 ENST00000223054.4
 MOSPD3
 motile sperm domain containing 3
chr12_-_56615693 0.13 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
 RNF41
 ring finger protein 41
chr16_-_30134266 0.13 ENST00000484663.1
ENST00000478356.1
 MAPK3
 mitogen-activated protein kinase 3
chr15_+_31619013 0.13 ENST00000307145.3
 KLF13
 Kruppel-like factor 13
chr7_+_33169142 0.13 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
 BBS9
 Bardet-Biedl syndrome 9
chr17_+_41177220 0.13 ENST00000587250.2
ENST00000544533.1
 RND2
 Rho family GTPase 2
chr7_+_73703728 0.13 ENST00000361545.5
ENST00000223398.6
 CLIP2
 CAP-GLY domain containing linker protein 2
chr10_-_15210615 0.13 ENST00000378150.1
 NMT2
 N-myristoyltransferase 2
chr7_+_76026832 0.13 ENST00000336517.4
 ZP3
 zona pellucida glycoprotein 3 (sperm receptor)
chr9_+_4985228 0.13 ENST00000381652.3
 JAK2
 Janus kinase 2
chr16_+_2933229 0.13 ENST00000573965.1
ENST00000572006.1
 FLYWCH2
 FLYWCH family member 2
chr19_+_49867181 0.13 ENST00000597546.1
 DKKL1
 dickkopf-like 1
chr12_+_57482665 0.13 ENST00000300131.3
 NAB2
 NGFI-A binding protein 2 (EGR1 binding protein 2)
chr1_+_162467595 0.13 ENST00000538489.1
ENST00000489294.1
 UHMK1
 U2AF homology motif (UHM) kinase 1
chr16_+_23569021 0.13 ENST00000567212.1
ENST00000567264.1
 UBFD1
 ubiquitin family domain containing 1
chr12_+_7341759 0.13 ENST00000455147.2
ENST00000540398.1
 PEX5
 peroxisomal biogenesis factor 5
chr2_+_23608064 0.13 ENST00000486442.1
 KLHL29
 kelch-like family member 29
chr1_-_19615744 0.13 ENST00000361640.4
 AKR7A3
 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr19_+_41082802 0.13 ENST00000600718.1
 SHKBP1
 SH3KBP1 binding protein 1
chr5_+_40679584 0.13 ENST00000302472.3
 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
chr15_+_41056255 0.13 ENST00000561160.1
ENST00000559445.1
 GCHFR
 GTP cyclohydrolase I feedback regulator
chr19_+_41082755 0.13 ENST00000291842.5
ENST00000600733.1
 SHKBP1
 SH3KBP1 binding protein 1
chr7_-_130353553 0.13 ENST00000330992.7
ENST00000445977.2
 COPG2
 coatomer protein complex, subunit gamma 2
chr2_-_179315786 0.13 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
chr12_+_7342441 0.13 ENST00000412720.2
ENST00000396637.3
 PEX5
 peroxisomal biogenesis factor 5
chr14_+_45366518 0.13 ENST00000557112.1
 C14orf28
 chromosome 14 open reading frame 28
chr2_+_27651519 0.13 ENST00000379863.3
 NRBP1
 nuclear receptor binding protein 1
chr17_+_17942594 0.13 ENST00000268719.4
 GID4
 GID complex subunit 4
chr19_+_1248547 0.13 ENST00000586757.1
ENST00000300952.2
 MIDN
 midnolin
chr1_+_65775204 0.13 ENST00000371069.4
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr15_+_41056218 0.13 ENST00000260447.4
 GCHFR
 GTP cyclohydrolase I feedback regulator
chr16_+_58283814 0.13 ENST00000443128.2
ENST00000219299.4
 CCDC113
 coiled-coil domain containing 113
chr9_+_4985016 0.12 ENST00000539801.1
 JAK2
 Janus kinase 2
chr12_+_100660909 0.12 ENST00000549687.1
 SCYL2
 SCY1-like 2 (S. cerevisiae)
chr14_+_24605389 0.12 ENST00000382708.3
ENST00000561435.1
 PSME1
 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr22_-_36903101 0.12 ENST00000397224.4
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr1_-_38471156 0.12 ENST00000373016.3
 FHL3
 four and a half LIM domains 3
chr10_+_23728198 0.12 ENST00000376495.3
 OTUD1
 OTU domain containing 1
chr6_-_43027105 0.12 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
 MRPL2
 mitochondrial ribosomal protein L2
chr14_+_93260569 0.12 ENST00000163416.2
 GOLGA5
 golgin A5
chr11_-_64014379 0.12 ENST00000309318.3
 PPP1R14B
 protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr22_-_36903069 0.12 ENST00000216187.6
ENST00000423980.1
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr7_+_100210133 0.12 ENST00000393950.2
ENST00000424091.2
 MOSPD3
 motile sperm domain containing 3
chr1_-_45956800 0.12 ENST00000538496.1
 TESK2
 testis-specific kinase 2
chr13_-_28024681 0.12 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
 MTIF3
 mitochondrial translational initiation factor 3
chr7_+_95401851 0.12 ENST00000447467.2
 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
chr20_-_39946237 0.12 ENST00000441102.2
ENST00000559234.1
 ZHX3
 zinc fingers and homeoboxes 3
chr17_-_7145475 0.12 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
 GABARAP
 GABA(A) receptor-associated protein
chr2_+_71295717 0.12 ENST00000418807.3
ENST00000443872.2
 NAGK
 N-acetylglucosamine kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 1.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.3 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.4 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.7 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.4 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 0.3 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.7 GO:1904415 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.1 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.2 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:0061043 regulation of vascular wound healing(GO:0061043)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.3 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.4 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.0 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0060180 female mating behavior(GO:0060180)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.0 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.0 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.0 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.0 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.0 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.0 GO:0006003 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.0 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.0 0.0 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.0 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 0.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.0 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.7 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.4 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.3 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.3 GO:0042806 fucose binding(GO:0042806)
0.0 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0 0.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.0 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.0 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.0 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.0 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0052724 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine