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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for KLF7

Z-value: 0.57

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
KLF7
ENSG00000118263.10 KLF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208031943_208031991-0.782.1e-02Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_19281203 0.26 ENST00000487415.2
 B9D1
 B9 protein domain 1
chr1_-_161102367 0.19 ENST00000464113.1
 DEDD
 death effector domain containing
chr2_-_188430478 0.16 ENST00000421427.1
 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr5_+_141348721 0.15 ENST00000507163.1
ENST00000394519.1
 RNF14
 ring finger protein 14
chr14_+_29234870 0.12 ENST00000382535.3
 FOXG1
 forkhead box G1
chr5_+_173315283 0.12 ENST00000265085.5
 CPEB4
 cytoplasmic polyadenylation element binding protein 4
chrX_-_92928557 0.12 ENST00000373079.3
ENST00000475430.2
 NAP1L3
 nucleosome assembly protein 1-like 3
chr2_+_97779233 0.10 ENST00000461153.2
ENST00000420699.2
 ANKRD36
 ankyrin repeat domain 36
chr3_+_186353756 0.09 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
 FETUB
 fetuin B
chr3_+_105085734 0.09 ENST00000306107.5
 ALCAM
 activated leukocyte cell adhesion molecule
chr5_+_141348598 0.09 ENST00000394520.2
ENST00000347642.3
 RNF14
 ring finger protein 14
chr5_+_176560007 0.08 ENST00000510954.1
ENST00000354179.4
 NSD1
 nuclear receptor binding SET domain protein 1
chr15_+_92937058 0.08 ENST00000268164.3
 ST8SIA2
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr20_-_2821756 0.08 ENST00000356872.3
ENST00000439542.1
 PCED1A
 PC-esterase domain containing 1A
chr6_-_30585009 0.08 ENST00000376511.2
 PPP1R10
 protein phosphatase 1, regulatory subunit 10
chr19_-_40931891 0.07 ENST00000357949.4
 SERTAD1
 SERTA domain containing 1
chr3_-_105588231 0.07 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr1_-_161102421 0.07 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
 DEDD
 death effector domain containing
chr15_+_96873921 0.07 ENST00000394166.3
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr20_-_2821271 0.07 ENST00000448755.1
ENST00000360652.2
 PCED1A
 PC-esterase domain containing 1A
chrX_+_102631844 0.07 ENST00000372634.1
ENST00000299872.7
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_-_19229248 0.07 ENST00000375341.3
 ALDH4A1
 aldehyde dehydrogenase 4 family, member A1
chr1_-_19229014 0.06 ENST00000538839.1
ENST00000290597.5
 ALDH4A1
 aldehyde dehydrogenase 4 family, member A1
chr12_-_49582593 0.06 ENST00000295766.5
 TUBA1A
 tubulin, alpha 1a
chr19_-_39390440 0.05 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2
 sirtuin 2
chr19_-_39390350 0.05 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chr2_+_67624430 0.05 ENST00000272342.5
 ETAA1
 Ewing tumor-associated antigen 1
chr8_-_6837602 0.04 ENST00000382692.2
 DEFA1
 defensin, alpha 1
chr16_+_20499024 0.04 ENST00000593357.1
 AC137056.1
 Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr3_-_105587879 0.04 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr8_-_6875778 0.04 ENST00000535841.1
ENST00000327857.2
 DEFA1B
DEFA3
 defensin, alpha 1B
defensin, alpha 3, neutrophil-specific
chr20_+_2821340 0.03 ENST00000380445.3
ENST00000380469.3
 VPS16
 vacuolar protein sorting 16 homolog (S. cerevisiae)
chr8_+_17104539 0.03 ENST00000521829.1
ENST00000521005.1
 VPS37A
 vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr6_+_31865552 0.03 ENST00000469372.1
ENST00000497706.1
 C2
 complement component 2
chr3_+_178866199 0.03 ENST00000263967.3
 PIK3CA
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr19_+_39390320 0.03 ENST00000576510.1
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr16_+_81772633 0.03 ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
ENST00000565054.1
 RP11-960L18.1
PLCG2
 RP11-960L18.1
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr6_-_109703600 0.02 ENST00000512821.1
 CD164
 CD164 molecule, sialomucin
chr8_-_17104356 0.02 ENST00000361272.4
ENST00000523917.1
 CNOT7
 CCR4-NOT transcription complex, subunit 7
chr15_+_92937144 0.02 ENST00000539113.1
ENST00000555434.1
 ST8SIA2
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr2_-_74710078 0.01 ENST00000290418.4
 CCDC142
 coiled-coil domain containing 142
chr2_+_74710194 0.01 ENST00000410003.1
ENST00000442235.2
ENST00000233623.5
 TTC31
 tetratricopeptide repeat domain 31
chr1_+_28157273 0.01 ENST00000311772.5
ENST00000236412.7
ENST00000373931.4
 PPP1R8
 protein phosphatase 1, regulatory subunit 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.0 GO:0035915 pore formation in membrane of other organism(GO:0035915)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)