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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for LHX2

Z-value: 0.60

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Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
LHX2
ENSG00000106689.6 LHX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX2hg19_v2_chr9_+_126773880_126773895,
hg19_v2_chr9_+_126777676_126777700		-0.039.5e-01Click!

Activity profile of LHX2 motif

Sorted Z-values of LHX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_29027696 1.28 ENST00000257189.4
 DSG3
 desmoglein 3
chr6_+_125524785 0.42 ENST00000392482.2
 TPD52L1
 tumor protein D52-like 1
chr1_+_160370344 0.37 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chr1_+_62439037 0.29 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr2_+_68961934 0.28 ENST00000409202.3
 ARHGAP25
 Rho GTPase activating protein 25
chr2_+_68961905 0.28 ENST00000295381.3
 ARHGAP25
 Rho GTPase activating protein 25
chr18_+_34124507 0.28 ENST00000591635.1
 FHOD3
 formin homology 2 domain containing 3
chrX_+_105937068 0.27 ENST00000324342.3
 RNF128
 ring finger protein 128, E3 ubiquitin protein ligase
chr6_+_30848557 0.27 ENST00000460944.2
ENST00000324771.8
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr4_-_90756769 0.26 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_122688090 0.25 ENST00000324189.4
ENST00000546192.1
 B3GNT4
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr10_-_116286656 0.24 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
 ABLIM1
 actin binding LIM protein 1
chr7_-_22234381 0.23 ENST00000458533.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr5_-_35938674 0.19 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
 CAPSL
 calcyphosine-like
chr4_+_69313145 0.18 ENST00000305363.4
 TMPRSS11E
 transmembrane protease, serine 11E
chr2_+_68962014 0.18 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr11_-_104972158 0.15 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
 CASP1
CARD16
CARD17
 caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_-_183560011 0.15 ENST00000367536.1
 NCF2
 neutrophil cytosolic factor 2
chr18_-_19994830 0.15 ENST00000525417.1
 CTAGE1
 cutaneous T-cell lymphoma-associated antigen 1
chr14_-_22005343 0.14 ENST00000327430.3
 SALL2
 spalt-like transcription factor 2
chr15_-_51535208 0.13 ENST00000405913.3
ENST00000559878.1
 CYP19A1
 cytochrome P450, family 19, subfamily A, polypeptide 1
chr19_+_42212501 0.12 ENST00000398599.4
 CEACAM5
 carcinoembryonic antigen-related cell adhesion molecule 5
chr4_-_159956333 0.12 ENST00000434826.2
 C4orf45
 chromosome 4 open reading frame 45
chr10_+_95326416 0.12 ENST00000371481.4
ENST00000371483.4
ENST00000604414.1
 FFAR4
 free fatty acid receptor 4
chr14_-_34420259 0.12 ENST00000250457.3
ENST00000547327.2
 EGLN3
 egl-9 family hypoxia-inducible factor 3
chr5_-_78281775 0.11 ENST00000396151.3
ENST00000565165.1
 ARSB
 arylsulfatase B
chr3_-_191000172 0.10 ENST00000427544.2
 UTS2B
 urotensin 2B
chr1_+_160709076 0.10 ENST00000359331.4
ENST00000495334.1
 SLAMF7
 SLAM family member 7
chrX_-_11284095 0.10 ENST00000303025.6
ENST00000534860.1
 ARHGAP6
 Rho GTPase activating protein 6
chr4_-_153332886 0.09 ENST00000603841.1
 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr2_+_145780725 0.09 ENST00000451478.1
 TEX41
 testis expressed 41 (non-protein coding)
chr6_+_26199737 0.09 ENST00000359985.1
 HIST1H2BF
 histone cluster 1, H2bf
chr4_+_147096837 0.09 ENST00000296581.5
ENST00000502781.1
 LSM6
 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_26199499 0.09 ENST00000377831.5
 HIST1H3D
 histone cluster 1, H3d
chr1_+_244515930 0.09 ENST00000366537.1
ENST00000308105.4
 C1orf100
 chromosome 1 open reading frame 100
chr7_-_112758589 0.09 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
 LINC00998
 long intergenic non-protein coding RNA 998
chr13_+_73632897 0.09 ENST00000377687.4
 KLF5
 Kruppel-like factor 5 (intestinal)
chr6_-_66417107 0.08 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
 EYS
 eyes shut homolog (Drosophila)
chr1_+_160709055 0.08 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
 SLAMF7
 SLAM family member 7
chr17_+_61086917 0.08 ENST00000424789.2
ENST00000389520.4
 TANC2
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_+_130339710 0.08 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr11_-_104827425 0.08 ENST00000393150.3
 CASP4
 caspase 4, apoptosis-related cysteine peptidase
chr4_+_88532028 0.08 ENST00000282478.7
 DSPP
 dentin sialophosphoprotein
chr14_+_22694606 0.07 ENST00000390463.3
 TRAV36DV7
 T cell receptor alpha variable 36/delta variable 7
chr6_-_26199471 0.07 ENST00000341023.1
 HIST1H2AD
 histone cluster 1, H2ad
chr4_+_128554081 0.07 ENST00000335251.6
ENST00000296461.5
 INTU
 inturned planar cell polarity protein
chr8_+_52730143 0.07 ENST00000415643.1
 AC090186.1
 Uncharacterized protein
chr17_-_7760457 0.07 ENST00000576384.1
 LSMD1
 LSM domain containing 1
chr4_-_120243545 0.07 ENST00000274024.3
 FABP2
 fatty acid binding protein 2, intestinal
chr2_+_145780767 0.07 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
 TEX41
 testis expressed 41 (non-protein coding)
chr3_+_35722487 0.07 ENST00000441454.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr12_-_100656134 0.06 ENST00000548313.1
 DEPDC4
 DEP domain containing 4
chr9_-_139137648 0.06 ENST00000358701.5
 QSOX2
 quiescin Q6 sulfhydryl oxidase 2
chr11_+_27076764 0.06 ENST00000525090.1
 BBOX1
 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_+_63606373 0.06 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr1_+_152975488 0.06 ENST00000542696.1
 SPRR3
 small proline-rich protein 3
chr2_+_102953608 0.06 ENST00000311734.2
ENST00000409584.1
 IL1RL1
 interleukin 1 receptor-like 1
chr21_-_27423339 0.06 ENST00000415997.1
 APP
 amyloid beta (A4) precursor protein
chr3_+_57881966 0.06 ENST00000495364.1
 SLMAP
 sarcolemma associated protein
chr3_+_62936098 0.06 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
 LINC00698
 long intergenic non-protein coding RNA 698
chr1_-_168464875 0.06 ENST00000422253.1
 RP5-968D22.3
 RP5-968D22.3
chr4_-_100575781 0.06 ENST00000511828.1
 RP11-766F14.2
 Protein LOC285556
chr3_+_147795932 0.06 ENST00000490465.1
 RP11-639B1.1
 RP11-639B1.1
chr2_+_145780739 0.05 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
 TEX41
 testis expressed 41 (non-protein coding)
chr3_+_38017264 0.05 ENST00000436654.1
 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr14_+_56584414 0.05 ENST00000559044.1
 PELI2
 pellino E3 ubiquitin protein ligase family member 2
chr6_+_123038689 0.05 ENST00000354275.2
ENST00000368446.1
 PKIB
 protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr10_-_61900762 0.05 ENST00000355288.2
 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_69864993 0.05 ENST00000555373.1
 ERH
 enhancer of rudimentary homolog (Drosophila)
chr15_+_69854027 0.05 ENST00000498938.2
 RP11-279F6.1
 RP11-279F6.1
chr9_-_77643307 0.04 ENST00000376834.3
ENST00000376830.3
 C9orf41
 chromosome 9 open reading frame 41
chr6_-_27841289 0.04 ENST00000355981.2
 HIST1H4L
 histone cluster 1, H4l
chr8_-_109260897 0.04 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
 EIF3E
 eukaryotic translation initiation factor 3, subunit E
chr7_+_37960163 0.04 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
 EPDR1
 ependymin related 1
chr9_+_116207007 0.04 ENST00000374140.2
 RGS3
 regulator of G-protein signaling 3
chr2_+_120436733 0.04 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
 TMEM177
 transmembrane protein 177
chr4_+_70796784 0.04 ENST00000246891.4
ENST00000444405.3
 CSN1S1
 casein alpha s1
chr16_-_23652570 0.04 ENST00000261584.4
 PALB2
 partner and localizer of BRCA2
chr13_+_78315466 0.04 ENST00000314070.5
ENST00000462234.1
 SLAIN1
 SLAIN motif family, member 1
chr12_+_27932803 0.04 ENST00000381271.2
 KLHL42
 kelch-like family member 42
chr21_+_35014706 0.04 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
 ITSN1
 intersectin 1 (SH3 domain protein)
chr2_-_112237835 0.04 ENST00000442293.1
ENST00000439494.1
 MIR4435-1HG
 MIR4435-1 host gene (non-protein coding)
chr2_+_103035102 0.04 ENST00000264260.2
 IL18RAP
 interleukin 18 receptor accessory protein
chr14_+_69865401 0.04 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
 SLC39A9
 solute carrier family 39, member 9
chr12_+_128399965 0.04 ENST00000540882.1
ENST00000542089.1
 LINC00507
 long intergenic non-protein coding RNA 507
chr11_+_64001962 0.04 ENST00000309422.2
 VEGFB
 vascular endothelial growth factor B
chr2_+_234216454 0.03 ENST00000447536.1
ENST00000409110.1
 SAG
 S-antigen; retina and pineal gland (arrestin)
chr1_-_89591749 0.03 ENST00000370466.3
 GBP2
 guanylate binding protein 2, interferon-inducible
chr1_+_160709029 0.03 ENST00000444090.2
ENST00000441662.2
 SLAMF7
 SLAM family member 7
chr13_-_19755975 0.03 ENST00000400113.3
 TUBA3C
 tubulin, alpha 3c
chr12_+_9980069 0.03 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
 KLRF1
 killer cell lectin-like receptor subfamily F, member 1
chr16_-_66864806 0.03 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
 NAE1
 NEDD8 activating enzyme E1 subunit 1
chr4_-_109541539 0.03 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
 RPL34-AS1
 RPL34 antisense RNA 1 (head to head)
chr3_-_180707306 0.03 ENST00000479269.1
 DNAJC19
 DnaJ (Hsp40) homolog, subfamily C, member 19
chr8_+_76452097 0.03 ENST00000396423.2
 HNF4G
 hepatocyte nuclear factor 4, gamma
chr17_-_39324424 0.03 ENST00000391356.2
 KRTAP4-3
 keratin associated protein 4-3
chr16_+_31213206 0.03 ENST00000561916.2
 C16orf98
 chromosome 16 open reading frame 98
chrX_-_20074895 0.03 ENST00000543767.1
 MAP7D2
 MAP7 domain containing 2
chrX_+_30233668 0.03 ENST00000378988.4
 MAGEB2
 melanoma antigen family B, 2
chr3_+_57882024 0.03 ENST00000494088.1
 SLMAP
 sarcolemma associated protein
chr12_+_6309517 0.03 ENST00000382519.4
ENST00000009180.4
 CD9
 CD9 molecule
chr2_-_55496174 0.03 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
 MTIF2
 mitochondrial translational initiation factor 2
chr17_-_39140549 0.03 ENST00000377755.4
 KRT40
 keratin 40
chr5_-_156536126 0.03 ENST00000522593.1
 HAVCR2
 hepatitis A virus cellular receptor 2
chr18_+_3466248 0.03 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
 RP11-838N2.4
 RP11-838N2.4
chr12_+_6554021 0.03 ENST00000266557.3
 CD27
 CD27 molecule
chr16_+_24266874 0.03 ENST00000005284.3
 CACNG3
 calcium channel, voltage-dependent, gamma subunit 3
chr14_-_78083112 0.02 ENST00000216484.2
 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
chr4_-_105416039 0.02 ENST00000394767.2
 CXXC4
 CXXC finger protein 4
chr21_+_34619079 0.02 ENST00000433395.2
 AP000295.9
 AP000295.9
chrY_-_20935572 0.02 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
 HSFY2
 heat shock transcription factor, Y linked 2
chr4_+_15471489 0.02 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
 CC2D2A
 coiled-coil and C2 domain containing 2A
chr7_-_54826920 0.02 ENST00000395535.3
ENST00000352861.4
 SEC61G
 Sec61 gamma subunit
chr16_+_31271274 0.02 ENST00000287497.8
ENST00000544665.3
 ITGAM
 integrin, alpha M (complement component 3 receptor 3 subunit)
chr2_-_128284020 0.02 ENST00000295321.4
ENST00000455721.2
 IWS1
 IWS1 homolog (S. cerevisiae)
chr12_-_11548496 0.02 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
 PRB2
PRB1
 proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr7_-_5998714 0.02 ENST00000539903.1
 RSPH10B
 radial spoke head 10 homolog B (Chlamydomonas)
chr13_+_19756173 0.02 ENST00000382988.2
 RP11-408E5.4
 RP11-408E5.4
chr2_+_234627424 0.02 ENST00000373409.3
 UGT1A4
 UDP glucuronosyltransferase 1 family, polypeptide A4
chr2_+_87769459 0.02 ENST00000414030.1
ENST00000437561.1
 LINC00152
 long intergenic non-protein coding RNA 152
chr15_+_58430567 0.02 ENST00000536493.1
 AQP9
 aquaporin 9
chrY_+_20708557 0.02 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
 HSFY1
 heat shock transcription factor, Y-linked 1
chr15_+_58430368 0.02 ENST00000558772.1
ENST00000219919.4
 AQP9
 aquaporin 9
chr17_-_57229155 0.02 ENST00000584089.1
 SKA2
 spindle and kinetochore associated complex subunit 2
chr6_+_112408768 0.02 ENST00000368656.2
ENST00000604268.1
 FAM229B
 family with sequence similarity 229, member B
chr12_-_74686314 0.02 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
 RP11-81H3.2
 RP11-81H3.2
chr17_-_38859996 0.02 ENST00000264651.2
 KRT24
 keratin 24
chr5_+_179921344 0.02 ENST00000261951.4
 CNOT6
 CCR4-NOT transcription complex, subunit 6
chr20_+_30697298 0.02 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr12_-_113574028 0.02 ENST00000546530.1
ENST00000261729.5
 RASAL1
 RAS protein activator like 1 (GAP1 like)
chr2_+_173686303 0.02 ENST00000397087.3
 RAPGEF4
 Rap guanine nucleotide exchange factor (GEF) 4
chr9_+_21440440 0.02 ENST00000276927.1
 IFNA1
 interferon, alpha 1
chr11_-_2323089 0.02 ENST00000456145.2
 C11orf21
 chromosome 11 open reading frame 21
chr2_-_166930131 0.02 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A
 sodium channel, voltage-gated, type I, alpha subunit
chr4_-_89951028 0.02 ENST00000506913.1
 FAM13A
 family with sequence similarity 13, member A
chr11_-_40315640 0.02 ENST00000278198.2
 LRRC4C
 leucine rich repeat containing 4C
chr11_+_94706973 0.01 ENST00000536741.1
 KDM4D
 lysine (K)-specific demethylase 4D
chr10_-_69597828 0.01 ENST00000339758.7
 DNAJC12
 DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_+_12510352 0.01 ENST00000298571.6
 LOH12CR1
 loss of heterozygosity, 12, chromosomal region 1
chr19_+_20188830 0.01 ENST00000418063.2
 ZNF90
 zinc finger protein 90
chr7_-_54826869 0.01 ENST00000450622.1
 SEC61G
 Sec61 gamma subunit
chr5_-_133702761 0.01 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
 CDKL3
 cyclin-dependent kinase-like 3
chr6_+_3259148 0.01 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
 PSMG4
 proteasome (prosome, macropain) assembly chaperone 4
chr3_-_160823040 0.01 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr16_+_23652773 0.01 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
 DCTN5
 dynactin 5 (p25)
chr1_+_182419261 0.01 ENST00000294854.8
ENST00000542961.1
 RGSL1
 regulator of G-protein signaling like 1
chr11_-_55703876 0.01 ENST00000301532.3
 OR5I1
 olfactory receptor, family 5, subfamily I, member 1
chr3_-_160823158 0.01 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr12_+_48722763 0.01 ENST00000335017.1
 H1FNT
 H1 histone family, member N, testis-specific
chr1_-_28527152 0.01 ENST00000321830.5
 AL353354.1
 Uncharacterized protein
chr5_-_175388327 0.01 ENST00000432305.2
ENST00000505969.1
 THOC3
 THO complex 3
chr2_-_208989225 0.01 ENST00000264376.4
 CRYGD
 crystallin, gamma D
chr9_-_21202204 0.01 ENST00000239347.3
 IFNA7
 interferon, alpha 7
chr1_-_198509804 0.01 ENST00000489986.1
ENST00000367382.1
 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr8_+_55528627 0.01 ENST00000220676.1
 RP1
 retinitis pigmentosa 1 (autosomal dominant)
chr1_+_219347203 0.01 ENST00000366927.3
 LYPLAL1
 lysophospholipase-like 1
chr15_-_72563585 0.01 ENST00000287196.9
ENST00000260376.7
 PARP6
 poly (ADP-ribose) polymerase family, member 6
chr8_-_82395461 0.01 ENST00000256104.4
 FABP4
 fatty acid binding protein 4, adipocyte
chr14_+_22554680 0.01 ENST00000390451.2
 TRAV23DV6
 T cell receptor alpha variable 23/delta variable 6
chr10_+_96443204 0.00 ENST00000339022.5
 CYP2C18
 cytochrome P450, family 2, subfamily C, polypeptide 18
chr14_+_27342334 0.00 ENST00000548170.1
ENST00000552926.1
 RP11-384J4.1
 RP11-384J4.1
chr12_-_118797475 0.00 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
 TAOK3
 TAO kinase 3
chr3_+_35722424 0.00 ENST00000396481.2
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr20_-_31989307 0.00 ENST00000473997.1
ENST00000544843.1
ENST00000346416.2
ENST00000357886.4
ENST00000339269.5
 CDK5RAP1
 CDK5 regulatory subunit associated protein 1
chr7_-_151217166 0.00 ENST00000496004.1
 RHEB
 Ras homolog enriched in brain
chr12_+_16064106 0.00 ENST00000428559.2
 DERA
 deoxyribose-phosphate aldolase (putative)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.1 GO:0008217 regulation of blood pressure(GO:0008217)
0.1 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.3 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.0 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome