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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for MECOM

Z-value: 1.44

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Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
MECOM
ENSG00000085276.13 MECOM

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MECOMhg19_v2_chr3_-_168865522_168865536-0.206.3e-01Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_102142296 3.03 ENST00000376162.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_189839046 2.48 ENST00000304636.3
ENST00000317840.5
 COL3A1
 collagen, type III, alpha 1
chr5_+_92919043 2.21 ENST00000327111.3
 NR2F1
 nuclear receptor subfamily 2, group F, member 1
chr12_-_15038779 2.02 ENST00000228938.5
ENST00000539261.1
 MGP
 matrix Gla protein
chr12_-_47219733 1.91 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
 SLC38A4
 solute carrier family 38, member 4
chr3_-_145968923 1.72 ENST00000493382.1
ENST00000354952.2
ENST00000383083.2
 PLSCR4
 phospholipid scramblase 4
chrX_+_86772787 1.51 ENST00000373114.4
 KLHL4
 kelch-like family member 4
chr3_-_145968857 1.47 ENST00000433593.2
ENST00000476202.1
ENST00000460885.1
 PLSCR4
 phospholipid scramblase 4
chr17_-_66951474 1.45 ENST00000269080.2
 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
chr6_-_31514516 1.34 ENST00000303892.5
ENST00000483251.1
 ATP6V1G2
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr5_-_158526693 1.31 ENST00000380654.4
 EBF1
 early B-cell factor 1
chr5_-_158526756 1.31 ENST00000313708.6
ENST00000517373.1
 EBF1
 early B-cell factor 1
chr1_+_171060018 1.23 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
 FMO3
 flavin containing monooxygenase 3
chrX_+_66764375 1.22 ENST00000374690.3
 AR
 androgen receptor
chr9_-_95244781 1.11 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr3_+_99357319 1.06 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
 COL8A1
 collagen, type VIII, alpha 1
chr2_-_145275228 0.89 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr2_-_224467093 0.88 ENST00000305409.2
 SCG2
 secretogranin II
chr15_+_41057818 0.88 ENST00000558467.1
 GCHFR
 GTP cyclohydrolase I feedback regulator
chr13_+_76334498 0.87 ENST00000534657.1
 LMO7
 LIM domain 7
chr6_-_87804815 0.84 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide
chr1_+_109102652 0.73 ENST00000370035.3
ENST00000405454.1
 FAM102B
 family with sequence similarity 102, member B
chr1_-_232651312 0.69 ENST00000262861.4
 SIPA1L2
 signal-induced proliferation-associated 1 like 2
chr20_-_45984401 0.68 ENST00000311275.7
 ZMYND8
 zinc finger, MYND-type containing 8
chrX_+_102883620 0.68 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr2_-_214014959 0.68 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
 IKZF2
 IKAROS family zinc finger 2 (Helios)
chr20_-_30310336 0.65 ENST00000434194.1
ENST00000376062.2
 BCL2L1
 BCL2-like 1
chr6_-_52860171 0.64 ENST00000370963.4
 GSTA4
 glutathione S-transferase alpha 4
chr13_+_31309645 0.62 ENST00000380490.3
 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
chr9_+_134378289 0.58 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
 POMT1
 protein-O-mannosyltransferase 1
chr12_+_113860160 0.57 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
 SDSL
 serine dehydratase-like
chr5_-_127674883 0.55 ENST00000507835.1
 FBN2
 fibrillin 2
chr16_-_73093597 0.54 ENST00000397992.5
 ZFHX3
 zinc finger homeobox 3
chr12_+_15699286 0.54 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr12_+_113860042 0.53 ENST00000403593.4
 SDSL
 serine dehydratase-like
chr12_+_55248289 0.53 ENST00000308796.6
 MUCL1
 mucin-like 1
chr5_+_140739537 0.52 ENST00000522605.1
 PCDHGB2
 protocadherin gamma subfamily B, 2
chr1_-_179834311 0.51 ENST00000553856.1
 IFRG15
 Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr8_-_93029865 0.50 ENST00000422361.2
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_76334567 0.50 ENST00000321797.8
 LMO7
 LIM domain 7
chr15_-_37391507 0.49 ENST00000557796.2
ENST00000397620.2
 MEIS2
 Meis homeobox 2
chr6_-_53530474 0.49 ENST00000370905.3
 KLHL31
 kelch-like family member 31
chr7_+_17338239 0.48 ENST00000242057.4
 AHR
 aryl hydrocarbon receptor
chrX_-_62974941 0.47 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
 ARHGEF9
 Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_-_45985464 0.46 ENST00000458360.2
ENST00000262975.4
 ZMYND8
 zinc finger, MYND-type containing 8
chr11_+_65266507 0.45 ENST00000544868.1
 MALAT1
 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr20_-_45985414 0.45 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
 ZMYND8
 zinc finger, MYND-type containing 8
chr20_-_45985172 0.44 ENST00000536340.1
 ZMYND8
 zinc finger, MYND-type containing 8
chr5_-_64920115 0.43 ENST00000381018.3
ENST00000274327.7
 TRIM23
 tripartite motif containing 23
chrX_-_106243451 0.42 ENST00000355610.4
ENST00000535534.1
 MORC4
 MORC family CW-type zinc finger 4
chr2_+_97779233 0.41 ENST00000461153.2
ENST00000420699.2
 ANKRD36
 ankyrin repeat domain 36
chr12_+_7169887 0.41 ENST00000542978.1
 C1S
 complement component 1, s subcomponent
chr5_+_118965244 0.41 ENST00000515256.1
ENST00000509264.1
 FAM170A
 family with sequence similarity 170, member A
chr4_-_52883786 0.39 ENST00000343457.3
 LRRC66
 leucine rich repeat containing 66
chr8_-_122653630 0.38 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr11_+_17316870 0.38 ENST00000458064.2
 NUCB2
 nucleobindin 2
chr4_-_74847800 0.37 ENST00000296029.3
 PF4
 platelet factor 4
chr6_-_52859968 0.36 ENST00000370959.1
 GSTA4
 glutathione S-transferase alpha 4
chr16_-_27899478 0.36 ENST00000380897.3
 GSG1L
 GSG1-like
chr12_+_57522258 0.36 ENST00000553277.1
ENST00000243077.3
 LRP1
 low density lipoprotein receptor-related protein 1
chr11_+_12115543 0.35 ENST00000537344.1
ENST00000532179.1
ENST00000526065.1
 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
chr15_-_37392086 0.35 ENST00000561208.1
 MEIS2
 Meis homeobox 2
chr15_-_79103757 0.34 ENST00000388820.4
 ADAMTS7
 ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr1_+_74701062 0.33 ENST00000326637.3
 TNNI3K
 TNNI3 interacting kinase
chr2_+_242289502 0.33 ENST00000451310.1
 SEPT2
 septin 2
chr8_-_133637624 0.33 ENST00000522789.1
 LRRC6
 leucine rich repeat containing 6
chr3_-_178984759 0.32 ENST00000349697.2
ENST00000497599.1
 KCNMB3
 potassium large conductance calcium-activated channel, subfamily M beta member 3
chr7_-_8302207 0.32 ENST00000407906.1
 ICA1
 islet cell autoantigen 1, 69kDa
chr9_+_82186872 0.31 ENST00000376544.3
ENST00000376520.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr16_+_33204156 0.31 ENST00000398667.4
 TP53TG3C
 TP53 target 3C
chr6_-_41168920 0.31 ENST00000483722.1
 TREML2
 triggering receptor expressed on myeloid cells-like 2
chr20_+_15177480 0.31 ENST00000402914.1
 MACROD2
 MACRO domain containing 2
chr18_-_12656715 0.30 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
 SPIRE1
 spire-type actin nucleation factor 1
chr2_-_56150910 0.29 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
 EFEMP1
 EGF containing fibulin-like extracellular matrix protein 1
chr14_-_24551195 0.29 ENST00000560550.1
 NRL
 neural retina leucine zipper
chr22_-_31688381 0.29 ENST00000487265.2
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr9_-_13175823 0.28 ENST00000545857.1
 MPDZ
 multiple PDZ domain protein
chr17_-_29648761 0.28 ENST00000247270.3
ENST00000462804.2
 EVI2A
 ecotropic viral integration site 2A
chr15_-_102285007 0.27 ENST00000560292.2
 RP11-89K11.1
 Uncharacterized protein
chr2_-_145275211 0.27 ENST00000462355.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr15_+_100348193 0.27 ENST00000558188.1
 CTD-2054N24.2
 Uncharacterized protein
chr1_-_238054094 0.27 ENST00000366570.4
 ZP4
 zona pellucida glycoprotein 4
chr2_-_1629176 0.26 ENST00000366424.2
 AC144450.2
 AC144450.2
chr9_+_82187487 0.26 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr10_-_49459800 0.26 ENST00000305531.3
 FRMPD2
 FERM and PDZ domain containing 2
chr12_-_76879852 0.25 ENST00000548341.1
 OSBPL8
 oxysterol binding protein-like 8
chr1_-_98386543 0.25 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
 DPYD
 dihydropyrimidine dehydrogenase
chr15_-_48470544 0.25 ENST00000267836.6
 MYEF2
 myelin expression factor 2
chr2_-_157189180 0.24 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr22_-_30866564 0.23 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
 SEC14L3
 SEC14-like 3 (S. cerevisiae)
chr2_+_27805880 0.23 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
 ZNF512
 zinc finger protein 512
chr6_+_31514622 0.23 ENST00000376146.4
 NFKBIL1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chrX_-_85302531 0.23 ENST00000537751.1
ENST00000358786.4
ENST00000357749.2
 CHM
 choroideremia (Rab escort protein 1)
chr9_+_82186682 0.22 ENST00000376552.2
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr17_-_43138357 0.22 ENST00000342350.5
 DCAKD
 dephospho-CoA kinase domain containing
chr14_-_76447494 0.22 ENST00000238682.3
 TGFB3
 transforming growth factor, beta 3
chr14_+_22458631 0.22 ENST00000390444.1
 TRAV16
 T cell receptor alpha variable 16
chr5_+_102201509 0.22 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr13_-_103053946 0.21 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr6_+_69942298 0.21 ENST00000238918.8
 BAI3
 brain-specific angiogenesis inhibitor 3
chr21_-_28338732 0.21 ENST00000284987.5
 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr8_+_11351494 0.21 ENST00000259089.4
 BLK
 B lymphoid tyrosine kinase
chrX_+_129473916 0.21 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_+_102201430 0.20 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr19_+_36630454 0.20 ENST00000246533.3
 CAPNS1
 calpain, small subunit 1
chr8_-_93029520 0.20 ENST00000521553.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_102201722 0.20 ENST00000274392.9
ENST00000455264.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr19_-_20844343 0.20 ENST00000595405.1
 ZNF626
 zinc finger protein 626
chr15_-_55562582 0.19 ENST00000396307.2
 RAB27A
 RAB27A, member RAS oncogene family
chr14_-_24551137 0.19 ENST00000396995.1
 NRL
 neural retina leucine zipper
chr14_+_24584508 0.19 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
 DCAF11
 DDB1 and CUL4 associated factor 11
chr6_-_154831779 0.19 ENST00000607772.1
 CNKSR3
 CNKSR family member 3
chr22_-_31688431 0.19 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr2_-_64568781 0.18 ENST00000424119.1
 AC114752.3
 AC114752.3
chr10_+_78078088 0.18 ENST00000496424.2
 C10orf11
 chromosome 10 open reading frame 11
chr8_+_11351876 0.18 ENST00000529894.1
 BLK
 B lymphoid tyrosine kinase
chr2_+_55746746 0.18 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
 CCDC104
 coiled-coil domain containing 104
chr12_+_124457746 0.18 ENST00000392404.3
ENST00000538932.2
ENST00000337815.4
ENST00000540762.2
 ZNF664
FAM101A
 zinc finger protein 664
family with sequence similarity 101, member A
chr15_-_48470558 0.17 ENST00000324324.7
 MYEF2
 myelin expression factor 2
chr14_-_39639523 0.17 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
 TRAPPC6B
 trafficking protein particle complex 6B
chr8_+_42552533 0.17 ENST00000289957.2
 CHRNB3
 cholinergic receptor, nicotinic, beta 3 (neuronal)
chr15_-_83837983 0.17 ENST00000562702.1
 HDGFRP3
 Hepatoma-derived growth factor-related protein 3
chr16_+_28943260 0.17 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
 CD19
 CD19 molecule
chr8_+_134203273 0.16 ENST00000250160.6
 WISP1
 WNT1 inducible signaling pathway protein 1
chr3_+_108541608 0.16 ENST00000426646.1
 TRAT1
 T cell receptor associated transmembrane adaptor 1
chr2_+_55746722 0.16 ENST00000339012.3
 CCDC104
 coiled-coil domain containing 104
chr2_+_204571198 0.16 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
 CD28
 CD28 molecule
chr7_-_33140498 0.15 ENST00000448915.1
 RP9
 retinitis pigmentosa 9 (autosomal dominant)
chr16_-_71758602 0.15 ENST00000568954.1
 PHLPP2
 PH domain and leucine rich repeat protein phosphatase 2
chr17_-_32484313 0.14 ENST00000359872.6
 ASIC2
 acid-sensing (proton-gated) ion channel 2
chr2_+_37571717 0.14 ENST00000338415.3
ENST00000404976.1
 QPCT
 glutaminyl-peptide cyclotransferase
chr6_+_31515337 0.14 ENST00000376148.4
ENST00000376145.4
 NFKBIL1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr12_+_53836339 0.14 ENST00000549135.1
 PRR13
 proline rich 13
chr19_+_22235310 0.14 ENST00000600162.1
 ZNF257
 zinc finger protein 257
chr17_-_37308824 0.14 ENST00000415163.1
ENST00000441877.1
ENST00000444911.2
 PLXDC1
 plexin domain containing 1
chr12_+_53835539 0.13 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
 PRR13
 proline rich 13
chr3_+_108541545 0.13 ENST00000295756.6
 TRAT1
 T cell receptor associated transmembrane adaptor 1
chr3_+_119013185 0.13 ENST00000264245.4
 ARHGAP31
 Rho GTPase activating protein 31
chr5_-_138862326 0.13 ENST00000330794.4
 TMEM173
 transmembrane protein 173
chr9_-_130341268 0.13 ENST00000373314.3
 FAM129B
 family with sequence similarity 129, member B
chr7_+_73275483 0.13 ENST00000320531.2
 WBSCR28
 Williams-Beuren syndrome chromosome region 28
chr15_+_42566384 0.13 ENST00000440615.2
ENST00000318010.8
 GANC
 glucosidase, alpha; neutral C
chr1_-_208084729 0.12 ENST00000310833.7
ENST00000356522.4
 CD34
 CD34 molecule
chr17_-_37309480 0.12 ENST00000539608.1
 PLXDC1
 plexin domain containing 1
chr4_-_40859132 0.12 ENST00000543538.1
ENST00000502841.1
ENST00000504305.1
ENST00000513516.1
ENST00000510670.1
 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_-_109090106 0.12 ENST00000379951.2
 LEF1
 lymphoid enhancer-binding factor 1
chr4_-_76598544 0.11 ENST00000515457.1
ENST00000357854.3
 G3BP2
 GTPase activating protein (SH3 domain) binding protein 2
chr1_-_146696901 0.11 ENST00000369272.3
ENST00000441068.2
 FMO5
 flavin containing monooxygenase 5
chr18_+_18943554 0.11 ENST00000580732.2
 GREB1L
 growth regulation by estrogen in breast cancer-like
chr18_-_21891460 0.11 ENST00000357041.4
 OSBPL1A
 oxysterol binding protein-like 1A
chr10_+_38717074 0.10 ENST00000423687.1
 LINC00999
 long intergenic non-protein coding RNA 999
chr6_+_29624898 0.10 ENST00000396704.3
ENST00000483013.1
ENST00000490427.1
ENST00000416766.2
ENST00000376891.4
ENST00000376898.3
ENST00000396701.2
ENST00000494692.1
ENST00000431798.2
 MOG
 myelin oligodendrocyte glycoprotein
chr17_-_40346477 0.10 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
 GHDC
 GH3 domain containing
chr11_+_94300474 0.10 ENST00000299001.6
 PIWIL4
 piwi-like RNA-mediated gene silencing 4
chr13_+_49280951 0.10 ENST00000282018.3
 CYSLTR2
 cysteinyl leukotriene receptor 2
chr16_+_31225337 0.10 ENST00000322122.3
 TRIM72
 tripartite motif containing 72
chr8_+_39759794 0.10 ENST00000518804.1
ENST00000519154.1
ENST00000522495.1
ENST00000522840.1
 IDO1
 indoleamine 2,3-dioxygenase 1
chr7_-_76039000 0.10 ENST00000275560.3
 SRCRB4D
 scavenger receptor cysteine rich domain containing, group B (4 domains)
chr11_-_33891362 0.10 ENST00000395833.3
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr3_-_112738565 0.09 ENST00000383675.2
ENST00000314400.5
 C3orf17
 chromosome 3 open reading frame 17
chr2_+_44066101 0.09 ENST00000272286.2
 ABCG8
 ATP-binding cassette, sub-family G (WHITE), member 8
chr14_-_102701740 0.09 ENST00000561150.1
ENST00000522867.1
 MOK
 MOK protein kinase
chr7_-_100844193 0.09 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
 MOGAT3
 monoacylglycerol O-acyltransferase 3
chr2_+_172544182 0.09 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr7_+_44240520 0.08 ENST00000496112.1
ENST00000223369.2
 YKT6
 YKT6 v-SNARE homolog (S. cerevisiae)
chrX_+_135730297 0.08 ENST00000370629.2
 CD40LG
 CD40 ligand
chr11_-_18656028 0.08 ENST00000336349.5
 SPTY2D1
 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr16_-_90096309 0.08 ENST00000408886.2
 C16orf3
 chromosome 16 open reading frame 3
chr19_-_54106751 0.08 ENST00000600193.1
 CTB-167G5.5
 Uncharacterized protein
chr7_-_130418888 0.08 ENST00000310992.4
 KLF14
 Kruppel-like factor 14
chr14_-_25479811 0.08 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chrX_+_135730373 0.08 ENST00000370628.2
 CD40LG
 CD40 ligand
chr15_+_71185148 0.08 ENST00000443425.2
ENST00000560755.1
 LRRC49
 leucine rich repeat containing 49
chr4_+_189060573 0.07 ENST00000332517.3
 TRIML1
 tripartite motif family-like 1
chr5_+_125695805 0.07 ENST00000513040.1
 GRAMD3
 GRAM domain containing 3
chr1_+_192127578 0.07 ENST00000367460.3
 RGS18
 regulator of G-protein signaling 18
chr19_-_10614386 0.07 ENST00000171111.5
 KEAP1
 kelch-like ECH-associated protein 1
chr5_+_159895275 0.07 ENST00000517927.1
 MIR146A
 microRNA 146a
chr12_+_72079842 0.07 ENST00000266673.5
ENST00000550524.1
 TMEM19
 transmembrane protein 19
chr11_+_30252549 0.07 ENST00000254122.3
ENST00000417547.1
 FSHB
 follicle stimulating hormone, beta polypeptide
chr19_-_9785743 0.07 ENST00000537617.1
ENST00000589542.1
ENST00000590155.1
ENST00000541032.1
ENST00000588653.1
ENST00000448622.1
ENST00000453792.2
 ZNF562
 zinc finger protein 562
chr13_+_60971080 0.06 ENST00000377894.2
 TDRD3
 tudor domain containing 3
chr11_-_73689037 0.06 ENST00000544615.1
 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_151428735 0.06 ENST00000441356.1
 AC104777.2
 AC104777.2
chr22_+_36113919 0.06 ENST00000249044.2
 APOL5
 apolipoprotein L, 5
chr10_+_106034884 0.06 ENST00000369707.2
ENST00000429569.2
 GSTO2
 glutathione S-transferase omega 2
chr19_+_48497962 0.06 ENST00000596043.1
ENST00000597519.1
 ELSPBP1
 epididymal sperm binding protein 1
chr3_+_152552685 0.06 ENST00000305097.3
 P2RY1
 purinergic receptor P2Y, G-protein coupled, 1
chr19_+_48497901 0.06 ENST00000339841.2
 ELSPBP1
 epididymal sperm binding protein 1
chr15_-_64673630 0.06 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
 KIAA0101
 KIAA0101
chr2_+_172544011 0.06 ENST00000508530.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr3_-_45883558 0.06 ENST00000445698.1
ENST00000296135.6
 LZTFL1
 leucine zipper transcription factor-like 1
chr1_-_152009460 0.05 ENST00000271638.2
 S100A11
 S100 calcium binding protein A11
chr5_-_147162078 0.05 ENST00000507386.1
 JAKMIP2
 janus kinase and microtubule interacting protein 2
chr2_+_172543967 0.05 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr4_-_76598296 0.05 ENST00000395719.3
 G3BP2
 GTPase activating protein (SH3 domain) binding protein 2
chr12_+_106976678 0.05 ENST00000392842.1
 RFX4
 regulatory factor X, 4 (influences HLA class II expression)
chr5_+_54320078 0.05 ENST00000231009.2
 GZMK
 granzyme K (granzyme 3; tryptase II)
chr5_+_140787600 0.05 ENST00000520790.1
 PCDHGB6
 protocadherin gamma subfamily B, 6
chr19_-_20844368 0.05 ENST00000595094.1
ENST00000601440.1
ENST00000291750.6
 CTC-513N18.7
ZNF626
 CTC-513N18.7
zinc finger protein 626

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.3 2.0 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3 0.9 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.3 1.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 2.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 3.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 0.6 GO:0018032 protein amidation(GO:0018032)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 1.5 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.6 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.4 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.6 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.6 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.2 GO:0046125 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.6 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 1.3 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.0 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 1.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 2.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.3 0.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.3 2.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.2 GO:0004882 androgen receptor activity(GO:0004882)
0.2 3.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.6 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 2.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) R-SMAD binding(GO:0070412)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 3.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers