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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 1.34

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Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
MIXL1
ENSG00000185155.7 MIXL1
GSX1
ENSG00000169840.4 GSX1
BSX
ENSG00000188909.4 BSX
MEOX2
ENSG00000106511.5 MEOX2
LHX4
ENSG00000121454.4 LHX4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_1801994260.502.1e-01Click!
GSX1hg19_v2_chr13_+_28366780_283667800.403.3e-01Click!
MIXL1hg19_v2_chr1_+_226411319_2264113660.245.7e-01Click!
MEOX2hg19_v2_chr7_-_15726296_157264370.245.7e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_151034734 6.32 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr1_-_242612779 5.69 ENST00000427495.1
 PLD5
 phospholipase D family, member 5
chr19_-_51522955 4.31 ENST00000358789.3
 KLK10
 kallikrein-related peptidase 10
chr4_+_40198527 3.53 ENST00000381799.5
 RHOH
 ras homolog family member H
chr18_+_29027696 3.48 ENST00000257189.4
 DSG3
 desmoglein 3
chr1_+_62439037 3.23 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr13_-_86373536 2.10 ENST00000400286.2
 SLITRK6
 SLIT and NTRK-like family, member 6
chr5_+_66300446 2.00 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr12_+_107712173 1.97 ENST00000280758.5
ENST00000420571.2
 BTBD11
 BTB (POZ) domain containing 11
chr12_-_28123206 1.97 ENST00000542963.1
ENST00000535992.1
 PTHLH
 parathyroid hormone-like hormone
chr12_-_28122980 1.94 ENST00000395868.3
ENST00000534890.1
 PTHLH
 parathyroid hormone-like hormone
chr2_+_68961934 1.81 ENST00000409202.3
 ARHGAP25
 Rho GTPase activating protein 25
chr2_+_68961905 1.79 ENST00000295381.3
 ARHGAP25
 Rho GTPase activating protein 25
chr21_-_42219065 1.61 ENST00000400454.1
 DSCAM
 Down syndrome cell adhesion molecule
chr8_-_41166953 1.58 ENST00000220772.3
 SFRP1
 secreted frizzled-related protein 1
chr11_-_124190184 1.53 ENST00000357438.2
 OR8D2
 olfactory receptor, family 8, subfamily D, member 2
chr1_+_160370344 1.51 ENST00000368061.2
 VANGL2
 VANGL planar cell polarity protein 2
chr18_+_61554932 1.40 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr7_-_25268104 1.38 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr9_+_12693336 1.38 ENST00000381137.2
ENST00000388918.5
 TYRP1
 tyrosinase-related protein 1
chr10_+_24497704 1.37 ENST00000376456.4
ENST00000458595.1
 KIAA1217
 KIAA1217
chr19_-_51523412 1.34 ENST00000391805.1
ENST00000599077.1
 KLK10
 kallikrein-related peptidase 10
chr2_-_70780770 1.28 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA
 transforming growth factor, alpha
chr19_-_51523275 1.26 ENST00000309958.3
 KLK10
 kallikrein-related peptidase 10
chr8_-_139926236 1.23 ENST00000303045.6
ENST00000435777.1
 COL22A1
 collagen, type XXII, alpha 1
chr5_-_82969405 1.23 ENST00000510978.1
 HAPLN1
 hyaluronan and proteoglycan link protein 1
chr4_+_69313145 1.21 ENST00000305363.4
 TMPRSS11E
 transmembrane protease, serine 11E
chr10_+_118187379 1.21 ENST00000369230.3
 PNLIPRP3
 pancreatic lipase-related protein 3
chr5_+_36608422 1.21 ENST00000381918.3
 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_77356248 1.20 ENST00000296043.6
 SHROOM3
 shroom family member 3
chr8_-_42234745 1.12 ENST00000220812.2
 DKK4
 dickkopf WNT signaling pathway inhibitor 4
chr13_-_46716969 1.09 ENST00000435666.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_216003127 1.06 ENST00000412081.1
ENST00000272895.7
 ABCA12
 ATP-binding cassette, sub-family A (ABC1), member 12
chr6_-_136788001 1.02 ENST00000544465.1
 MAP7
 microtubule-associated protein 7
chr14_-_23652849 1.00 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
 SLC7A8
 solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr19_-_36001113 0.99 ENST00000434389.1
 DMKN
 dermokine
chr2_+_68962014 0.94 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr20_-_46415341 0.94 ENST00000484875.1
ENST00000361612.4
 SULF2
 sulfatase 2
chr20_-_46415297 0.94 ENST00000467815.1
ENST00000359930.4
 SULF2
 sulfatase 2
chr6_+_125540951 0.87 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chr12_+_41831485 0.86 ENST00000539469.2
ENST00000298919.7
 PDZRN4
 PDZ domain containing ring finger 4
chr3_+_111718173 0.85 ENST00000494932.1
 TAGLN3
 transgelin 3
chr3_+_111717600 0.85 ENST00000273368.4
 TAGLN3
 transgelin 3
chr3_+_111718036 0.84 ENST00000455401.2
 TAGLN3
 transgelin 3
chr6_-_32157947 0.83 ENST00000375050.4
 PBX2
 pre-B-cell leukemia homeobox 2
chr6_+_151042224 0.78 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr12_+_4385230 0.77 ENST00000536537.1
 CCND2
 cyclin D2
chr8_+_101170563 0.75 ENST00000520508.1
ENST00000388798.2
 SPAG1
 sperm associated antigen 1
chr8_+_105235572 0.74 ENST00000523362.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr12_+_44229846 0.74 ENST00000551577.1
ENST00000266534.3
 TMEM117
 transmembrane protein 117
chr11_-_117747434 0.74 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
 FXYD6
 FXYD domain containing ion transport regulator 6
chr11_-_117748138 0.74 ENST00000527717.1
 FXYD6
 FXYD domain containing ion transport regulator 6
chr6_+_130339710 0.73 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
chr12_-_28125638 0.73 ENST00000545234.1
 PTHLH
 parathyroid hormone-like hormone
chr3_+_111717511 0.73 ENST00000478951.1
ENST00000393917.2
 TAGLN3
 transgelin 3
chr1_+_209602771 0.72 ENST00000440276.1
 MIR205HG
 MIR205 host gene (non-protein coding)
chr12_-_28124903 0.72 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH
 parathyroid hormone-like hormone
chr11_-_117747607 0.71 ENST00000540359.1
ENST00000539526.1
 FXYD6
 FXYD domain containing ion transport regulator 6
chr8_-_17533838 0.71 ENST00000400046.1
 MTUS1
 microtubule associated tumor suppressor 1
chr6_+_47666275 0.71 ENST00000327753.3
ENST00000283303.2
 GPR115
 G protein-coupled receptor 115
chr2_-_70780572 0.69 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr10_-_105845674 0.69 ENST00000353479.5
ENST00000369733.3
 COL17A1
 collagen, type XVII, alpha 1
chr11_+_55578854 0.69 ENST00000333973.2
 OR5L1
 olfactory receptor, family 5, subfamily L, member 1
chr12_+_20963647 0.68 ENST00000381545.3
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr12_+_20963632 0.66 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr8_+_98900132 0.65 ENST00000520016.1
 MATN2
 matrilin 2
chr3_-_143567262 0.64 ENST00000474151.1
ENST00000316549.6
 SLC9A9
 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr6_-_66417107 0.63 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
 EYS
 eyes shut homolog (Drosophila)
chr6_-_155776966 0.62 ENST00000159060.2
 NOX3
 NADPH oxidase 3
chr3_+_189349162 0.61 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
 TP63
 tumor protein p63
chr12_+_122688090 0.61 ENST00000324189.4
ENST00000546192.1
 B3GNT4
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr17_-_64225508 0.61 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr11_-_102651343 0.61 ENST00000279441.4
ENST00000539681.1
 MMP10
 matrix metallopeptidase 10 (stromelysin 2)
chr5_-_1882858 0.61 ENST00000511126.1
ENST00000231357.2
 IRX4
 iroquois homeobox 4
chr11_-_104972158 0.60 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
 CASP1
CARD16
CARD17
 caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr8_-_86253888 0.60 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
 CA1
 carbonic anhydrase I
chr6_-_32784687 0.59 ENST00000447394.1
ENST00000438763.2
 HLA-DOB
 major histocompatibility complex, class II, DO beta
chr4_-_74486217 0.59 ENST00000335049.5
ENST00000307439.5
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr17_-_38956205 0.58 ENST00000306658.7
 KRT28
 keratin 28
chr11_+_121447469 0.58 ENST00000532694.1
ENST00000534286.1
 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
chr4_-_143227088 0.57 ENST00000511838.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_-_9694614 0.56 ENST00000330255.5
ENST00000571134.1
 DHRS7C
 dehydrogenase/reductase (SDR family) member 7C
chr17_+_39394250 0.56 ENST00000254072.6
 KRTAP9-8
 keratin associated protein 9-8
chr9_+_470288 0.56 ENST00000382303.1
 KANK1
 KN motif and ankyrin repeat domains 1
chr5_+_140227048 0.55 ENST00000532602.1
 PCDHA9
 protocadherin alpha 9
chr17_-_39274606 0.54 ENST00000391413.2
 KRTAP4-11
 keratin associated protein 4-11
chr4_-_143226979 0.53 ENST00000514525.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr6_+_26365443 0.53 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
 BTN3A2
 butyrophilin, subfamily 3, member A2
chr11_+_32851487 0.52 ENST00000257836.3
 PRRG4
 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr14_+_22739823 0.52 ENST00000390464.2
 TRAV38-1
 T cell receptor alpha variable 38-1
chrX_-_24690771 0.52 ENST00000379145.1
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr3_-_108248169 0.51 ENST00000273353.3
 MYH15
 myosin, heavy chain 15
chr11_-_118023490 0.51 ENST00000324727.4
 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
chr17_-_19015945 0.51 ENST00000573866.2
 SNORD3D
 small nucleolar RNA, C/D box 3D
chr18_+_61445007 0.50 ENST00000447428.1
ENST00000546027.1
 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr8_-_86290333 0.50 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
 CA1
 carbonic anhydrase I
chrX_+_134654540 0.49 ENST00000370752.4
 DDX26B
 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr4_-_123542224 0.49 ENST00000264497.3
 IL21
 interleukin 21
chr2_+_191045656 0.49 ENST00000443551.2
 C2orf88
 chromosome 2 open reading frame 88
chr1_+_156254070 0.49 ENST00000405535.2
ENST00000456810.1
 TMEM79
 transmembrane protein 79
chr10_-_50970322 0.48 ENST00000374103.4
 OGDHL
 oxoglutarate dehydrogenase-like
chr3_+_130569429 0.48 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr12_-_12715266 0.47 ENST00000228862.2
 DUSP16
 dual specificity phosphatase 16
chr14_-_54423529 0.47 ENST00000245451.4
ENST00000559087.1
 BMP4
 bone morphogenetic protein 4
chr12_+_19358228 0.47 ENST00000424268.1
ENST00000543806.1
 PLEKHA5
 pleckstrin homology domain containing, family A member 5
chr3_-_141747950 0.46 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr11_-_7847519 0.46 ENST00000328375.1
 OR5P3
 olfactory receptor, family 5, subfamily P, member 3
chr5_+_140201183 0.46 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
 PCDHA5
 protocadherin alpha 5
chr6_-_136847099 0.46 ENST00000438100.2
 MAP7
 microtubule-associated protein 7
chr15_+_101420028 0.44 ENST00000557963.1
ENST00000346623.6
 ALDH1A3
 aldehyde dehydrogenase 1 family, member A3
chr12_-_8814669 0.44 ENST00000535411.1
ENST00000540087.1
 MFAP5
 microfibrillar associated protein 5
chr2_+_191045562 0.43 ENST00000340623.4
 C2orf88
 chromosome 2 open reading frame 88
chr6_+_47624172 0.43 ENST00000507065.1
ENST00000296862.1
 GPR111
 G protein-coupled receptor 111
chr4_-_120243545 0.43 ENST00000274024.3
 FABP2
 fatty acid binding protein 2, intestinal
chr6_-_9933500 0.43 ENST00000492169.1
 OFCC1
 orofacial cleft 1 candidate 1
chr6_-_136847610 0.43 ENST00000454590.1
ENST00000432797.2
 MAP7
 microtubule-associated protein 7
chr9_-_5304432 0.42 ENST00000416837.1
ENST00000308420.3
 RLN2
 relaxin 2
chr12_-_89746173 0.42 ENST00000308385.6
 DUSP6
 dual specificity phosphatase 6
chr2_-_208031943 0.42 ENST00000421199.1
ENST00000457962.1
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr4_+_169013666 0.41 ENST00000359299.3
 ANXA10
 annexin A10
chr17_+_19091325 0.41 ENST00000584923.1
 SNORD3A
 small nucleolar RNA, C/D box 3A
chr4_-_87028478 0.41 ENST00000515400.1
ENST00000395157.3
 MAPK10
 mitogen-activated protein kinase 10
chr7_-_22234381 0.41 ENST00000458533.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_182850551 0.41 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
 PPP1R1C
 protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_+_29376592 0.41 ENST00000182377.4
 FAR2
 fatty acyl CoA reductase 2
chr11_-_104905840 0.41 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
 CASP1
 caspase 1, apoptosis-related cysteine peptidase
chr17_-_7167279 0.40 ENST00000571932.2
 CLDN7
 claudin 7
chr10_+_24755416 0.40 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
 KIAA1217
 KIAA1217
chr8_-_57026541 0.40 ENST00000311923.1
 MOS
 v-mos Moloney murine sarcoma viral oncogene homolog
chr11_-_36619771 0.40 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
 RAG2
 recombination activating gene 2
chr12_-_95510743 0.39 ENST00000551521.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr4_+_71200681 0.39 ENST00000273936.5
 CABS1
 calcium-binding protein, spermatid-specific 1
chr9_+_71944241 0.38 ENST00000257515.8
 FAM189A2
 family with sequence similarity 189, member A2
chr11_-_129062093 0.38 ENST00000310343.9
 ARHGAP32
 Rho GTPase activating protein 32
chr14_+_61654271 0.38 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
 PRKCH
 protein kinase C, eta
chr11_-_13517565 0.38 ENST00000282091.1
ENST00000529816.1
 PTH
 parathyroid hormone
chr12_+_21207503 0.38 ENST00000545916.1
 SLCO1B7
 solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_+_97868170 0.38 ENST00000437310.1
 OR5H14
 olfactory receptor, family 5, subfamily H, member 14
chr3_-_27764190 0.37 ENST00000537516.1
 EOMES
 eomesodermin
chr4_+_144354644 0.37 ENST00000512843.1
 GAB1
 GRB2-associated binding protein 1
chr16_-_4852915 0.37 ENST00000322048.7
 ROGDI
 rogdi homolog (Drosophila)
chr14_-_78083112 0.36 ENST00000216484.2
 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
chr5_+_140207536 0.36 ENST00000529310.1
ENST00000527624.1
 PCDHA6
 protocadherin alpha 6
chr19_-_43969796 0.36 ENST00000244333.3
 LYPD3
 LY6/PLAUR domain containing 3
chr16_+_76587314 0.36 ENST00000563764.1
 RP11-58C22.1
 Uncharacterized protein
chr7_-_22233442 0.35 ENST00000401957.2
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_180601139 0.35 ENST00000367590.4
ENST00000367589.3
 XPR1
 xenotropic and polytropic retrovirus receptor 1
chr18_-_61329118 0.35 ENST00000332821.8
ENST00000283752.5
 SERPINB3
 serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_+_82266053 0.35 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
 LPHN2
 latrophilin 2
chr18_-_3220106 0.35 ENST00000356443.4
ENST00000400569.3
 MYOM1
 myomesin 1
chr20_+_43803517 0.35 ENST00000243924.3
 PI3
 peptidase inhibitor 3, skin-derived
chr7_+_73245193 0.34 ENST00000340958.2
 CLDN4
 claudin 4
chr2_-_136678123 0.34 ENST00000422708.1
 DARS
 aspartyl-tRNA synthetase
chr18_-_53177984 0.34 ENST00000543082.1
 TCF4
 transcription factor 4
chr8_-_109799793 0.34 ENST00000297459.3
 TMEM74
 transmembrane protein 74
chr2_-_99871570 0.34 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
 LYG2
 lysozyme G-like 2
chr4_-_74486347 0.33 ENST00000342081.3
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr1_+_153747746 0.33 ENST00000368661.3
 SLC27A3
 solute carrier family 27 (fatty acid transporter), member 3
chr3_+_121774202 0.32 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
 CD86
 CD86 molecule
chr17_-_38938786 0.32 ENST00000301656.3
 KRT27
 keratin 27
chr4_+_70796784 0.32 ENST00000246891.4
ENST00000444405.3
 CSN1S1
 casein alpha s1
chr9_+_71986182 0.32 ENST00000303068.7
 FAM189A2
 family with sequence similarity 189, member A2
chr18_+_34124507 0.31 ENST00000591635.1
 FHOD3
 formin homology 2 domain containing 3
chr1_+_111415757 0.31 ENST00000429072.2
ENST00000271324.5
 CD53
 CD53 molecule
chr16_-_30122717 0.31 ENST00000566613.1
 GDPD3
 glycerophosphodiester phosphodiesterase domain containing 3
chr3_+_122044084 0.31 ENST00000264474.3
ENST00000479204.1
 CSTA
 cystatin A (stefin A)
chr3_-_98235962 0.31 ENST00000513873.1
 CLDND1
 claudin domain containing 1
chr8_-_91095099 0.30 ENST00000265431.3
 CALB1
 calbindin 1, 28kDa
chr17_+_39382900 0.30 ENST00000377721.3
ENST00000455970.2
 KRTAP9-2
 keratin associated protein 9-2
chr3_-_139258521 0.30 ENST00000483943.2
ENST00000232219.2
ENST00000492918.1
 RBP1
 retinol binding protein 1, cellular
chr7_+_129984630 0.30 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
 CPA5
 carboxypeptidase A5
chr3_-_191000172 0.30 ENST00000427544.2
 UTS2B
 urotensin 2B
chr7_-_130080977 0.30 ENST00000223208.5
 CEP41
 centrosomal protein 41kDa
chr11_+_55594695 0.30 ENST00000378397.1
 OR5L2
 olfactory receptor, family 5, subfamily L, member 2
chr6_-_32908792 0.30 ENST00000418107.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr14_-_67878917 0.29 ENST00000216446.4
 PLEK2
 pleckstrin 2
chr5_+_89770664 0.29 ENST00000503973.1
ENST00000399107.1
 POLR3G
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr6_-_111888474 0.29 ENST00000368735.1
 TRAF3IP2
 TRAF3 interacting protein 2
chr14_-_72458326 0.29 ENST00000542853.1
 AC005477.1
 AC005477.1
chr17_-_39324424 0.29 ENST00000391356.2
 KRTAP4-3
 keratin associated protein 4-3
chr15_-_68497657 0.28 ENST00000448060.2
ENST00000467889.1
 CALML4
 calmodulin-like 4
chr18_-_13915530 0.28 ENST00000327606.3
 MC2R
 melanocortin 2 receptor (adrenocorticotropic hormone)
chr5_+_89770696 0.28 ENST00000504930.1
ENST00000514483.1
 POLR3G
 polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr11_-_5323226 0.28 ENST00000380224.1
 OR51B4
 olfactory receptor, family 51, subfamily B, member 4
chr17_+_39261584 0.28 ENST00000391415.1
 KRTAP4-9
 keratin associated protein 4-9
chr8_-_124279627 0.28 ENST00000357082.4
 ZHX1-C8ORF76
 ZHX1-C8ORF76 readthrough
chr3_-_194188956 0.28 ENST00000256031.4
ENST00000446356.1
 ATP13A3
 ATPase type 13A3
chr1_+_158149737 0.28 ENST00000368171.3
 CD1D
 CD1d molecule
chr8_-_10512569 0.28 ENST00000382483.3
 RP1L1
 retinitis pigmentosa 1-like 1
chr7_-_111032971 0.28 ENST00000450877.1
 IMMP2L
 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_150738261 0.28 ENST00000448301.2
ENST00000368985.3
 CTSS
 cathepsin S
chr4_-_74486109 0.27 ENST00000395777.2
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr11_+_117947724 0.27 ENST00000534111.1
 TMPRSS4
 transmembrane protease, serine 4
chr1_-_92952433 0.27 ENST00000294702.5
 GFI1
 growth factor independent 1 transcription repressor
chr2_+_90211643 0.27 ENST00000390277.2
 IGKV3D-11
 immunoglobulin kappa variable 3D-11
chr14_+_22977587 0.27 ENST00000390504.1
 TRAJ33
 T cell receptor alpha joining 33
chr14_+_68286478 0.27 ENST00000487861.1
 RAD51B
 RAD51 paralog B
chr1_+_15256230 0.27 ENST00000376028.4
ENST00000400798.2
 KAZN
 kazrin, periplakin interacting protein
chr1_+_107682629 0.27 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
 NTNG1
 netrin G1
chr9_-_95166884 0.27 ENST00000375561.5
 OGN
 osteoglycin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.5 1.5 GO:0061346 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.4 1.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 2.1 GO:0060005 vestibular reflex(GO:0060005)
0.3 1.1 GO:0035627 ceramide transport(GO:0035627)
0.3 6.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3 0.5 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.3 0.3 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 1.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.4 GO:0070384 Harderian gland development(GO:0070384)
0.2 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.6 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 6.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 1.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.2 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 0.6 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 0.5 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 1.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.4 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.6 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 2.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.3 GO:0044782 cilium organization(GO:0044782)
0.1 0.4 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.5 GO:1902224 ketone body metabolic process(GO:1902224)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 1.0 GO:0045176 apical protein localization(GO:0045176)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.2 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.1 0.6 GO:0048840 otolith development(GO:0048840)
0.1 0.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.3 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.2 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 2.1 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 3.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.4 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.3 GO:0002396 MHC protein complex assembly(GO:0002396)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 2.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 4.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 5.8 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.5 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 3.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0009798 axis specification(GO:0009798)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.0 GO:0051884 anagen(GO:0042640) regulation of anagen(GO:0051884) positive regulation of anagen(GO:0051885)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0051387 negative regulation of norepinephrine secretion(GO:0010700) negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.0 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 2.1 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.0 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.0 GO:0034367 macromolecular complex remodeling(GO:0034367) protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369) low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.2 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0002881 microglial cell activation involved in immune response(GO:0002282) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.0 GO:0019230 proprioception(GO:0019230)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.0 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0060187 cell pole(GO:0060187)
0.2 1.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 0.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 1.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 4.1 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 3.4 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.0 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 4.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.0 GO:0099738 cell cortex region(GO:0099738)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.3 6.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 3.6 GO:0005549 odorant binding(GO:0005549)
0.2 1.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 5.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.1 GO:0004064 arylesterase activity(GO:0004064)
0.1 3.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.7 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 2.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 1.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 8.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.3 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.0 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 1.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 4.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 4.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 5.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 2.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 7.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling