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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for MSX1

Z-value: 1.29

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Transcription factors associated with MSX1

Gene Symbol Gene ID Gene Info
MSX1
ENSG00000163132.6 MSX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX1hg19_v2_chr4_+_4861385_48613980.714.7e-02Click!

Activity profile of MSX1 motif

Sorted Z-values of MSX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_38172863 3.53 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chr5_-_75919253 1.13 ENST00000296641.4
 F2RL2
 coagulation factor II (thrombin) receptor-like 2
chr2_-_145278475 1.08 ENST00000558170.2
 ZEB2
 zinc finger E-box binding homeobox 2
chr8_+_97597148 0.98 ENST00000521590.1
 SDC2
 syndecan 2
chr2_-_158345462 0.79 ENST00000439355.1
ENST00000540637.1
 CYTIP
 cytohesin 1 interacting protein
chr9_+_79074068 0.76 ENST00000444201.2
ENST00000376730.4
 GCNT1
 glucosaminyl (N-acetyl) transferase 1, core 2
chr1_-_72566613 0.75 ENST00000306821.3
 NEGR1
 neuronal growth regulator 1
chr6_+_28249332 0.71 ENST00000259883.3
 PGBD1
 piggyBac transposable element derived 1
chr6_+_28249299 0.71 ENST00000405948.2
 PGBD1
 piggyBac transposable element derived 1
chr9_+_90112117 0.71 ENST00000358077.5
 DAPK1
 death-associated protein kinase 1
chr5_+_82767583 0.68 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
 VCAN
 versican
chr5_+_82767487 0.65 ENST00000343200.5
ENST00000342785.4
 VCAN
 versican
chr5_+_82767284 0.64 ENST00000265077.3
 VCAN
 versican
chr14_+_52327109 0.64 ENST00000335281.4
 GNG2
 guanine nucleotide binding protein (G protein), gamma 2
chr19_-_53662257 0.62 ENST00000599096.1
ENST00000334197.7
ENST00000597183.1
ENST00000601804.1
ENST00000601469.2
ENST00000452676.2
 ZNF347
 zinc finger protein 347
chr5_-_75919217 0.58 ENST00000504899.1
 F2RL2
 coagulation factor II (thrombin) receptor-like 2
chr18_-_70532906 0.48 ENST00000299430.2
ENST00000397929.1
 NETO1
 neuropilin (NRP) and tolloid (TLL)-like 1
chr5_+_67586465 0.48 ENST00000336483.5
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_57547454 0.46 ENST00000556376.2
 HOPX
 HOP homeobox
chr11_+_12766583 0.34 ENST00000361985.2
 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_+_210501589 0.31 ENST00000413764.2
ENST00000541565.1
 HHAT
 hedgehog acyltransferase
chr11_+_12132117 0.30 ENST00000256194.4
 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
chr16_-_66583701 0.29 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
 TK2
 thymidine kinase 2, mitochondrial
chr6_+_28092338 0.29 ENST00000340487.4
 ZSCAN16
 zinc finger and SCAN domain containing 16
chr19_-_53757941 0.28 ENST00000594517.1
ENST00000601413.1
ENST00000594681.1
 ZNF677
 zinc finger protein 677
chr18_-_5396271 0.28 ENST00000579951.1
 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
chr5_+_140762268 0.26 ENST00000518325.1
 PCDHGA7
 protocadherin gamma subfamily A, 7
chr2_+_158114051 0.25 ENST00000259056.4
 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr7_+_148287657 0.25 ENST00000307003.2
 C7orf33
 chromosome 7 open reading frame 33
chr11_+_101785727 0.25 ENST00000263468.8
 KIAA1377
 KIAA1377
chr16_-_66584059 0.24 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
 TK2
 thymidine kinase 2, mitochondrial
chr17_-_5321549 0.24 ENST00000572809.1
 NUP88
 nucleoporin 88kDa
chr20_+_56964169 0.23 ENST00000475243.1
 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
chr8_-_25281747 0.21 ENST00000421054.2
 GNRH1
 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr6_+_136172820 0.21 ENST00000308191.6
 PDE7B
 phosphodiesterase 7B
chr1_+_224370873 0.21 ENST00000323699.4
ENST00000391877.3
 DEGS1
 delta(4)-desaturase, sphingolipid 1
chr6_-_109777128 0.21 ENST00000358807.3
ENST00000358577.3
 MICAL1
 microtubule associated monooxygenase, calponin and LIM domain containing 1
chr6_+_26240561 0.20 ENST00000377745.2
 HIST1H4F
 histone cluster 1, H4f
chr19_-_53758094 0.20 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
 ZNF677
 zinc finger protein 677
chr17_-_8113542 0.20 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
 AURKB
 aurora kinase B
chr10_+_17270214 0.20 ENST00000544301.1
 VIM
 vimentin
chr16_+_21689835 0.20 ENST00000286149.4
ENST00000388958.3
 OTOA
 otoancorin
chr13_+_50570019 0.20 ENST00000442421.1
 TRIM13
 tripartite motif containing 13
chr12_+_54422142 0.19 ENST00000243108.4
 HOXC6
 homeobox C6
chr13_+_49551020 0.18 ENST00000541916.1
 FNDC3A
 fibronectin type III domain containing 3A
chr11_-_102401469 0.18 ENST00000260227.4
 MMP7
 matrix metallopeptidase 7 (matrilysin, uterine)
chr12_-_10978957 0.17 ENST00000240619.2
 TAS2R10
 taste receptor, type 2, member 10
chr1_-_54405773 0.17 ENST00000371376.1
 HSPB11
 heat shock protein family B (small), member 11
chr1_+_84630645 0.17 ENST00000394839.2
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr10_+_13142225 0.16 ENST00000378747.3
 OPTN
 optineurin
chr11_+_61197508 0.16 ENST00000541135.1
ENST00000301761.2
 RP11-286N22.8
SDHAF2
 Uncharacterized protein
succinate dehydrogenase complex assembly factor 2
chr6_+_131894284 0.15 ENST00000368087.3
ENST00000356962.2
 ARG1
 arginase 1
chr6_+_6588316 0.15 ENST00000379953.2
 LY86
 lymphocyte antigen 86
chr4_-_186696425 0.15 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr16_-_71518504 0.15 ENST00000565100.2
 ZNF19
 zinc finger protein 19
chr1_+_158985457 0.15 ENST00000567661.1
ENST00000474473.1
 IFI16
 interferon, gamma-inducible protein 16
chr5_+_175490540 0.14 ENST00000515817.1
 FAM153B
 family with sequence similarity 153, member B
chr4_+_113568207 0.14 ENST00000511529.1
 LARP7
 La ribonucleoprotein domain family, member 7
chr15_-_95870310 0.14 ENST00000508732.2
 CTD-2536I1.1
 CTD-2536I1.1
chr2_-_169746878 0.13 ENST00000282074.2
 SPC25
 SPC25, NDC80 kinetochore complex component
chr14_+_52327350 0.13 ENST00000555472.1
ENST00000556766.1
 GNG2
 guanine nucleotide binding protein (G protein), gamma 2
chr11_+_62037622 0.12 ENST00000227918.2
ENST00000525380.1
 SCGB2A2
 secretoglobin, family 2A, member 2
chr13_+_103459704 0.12 ENST00000602836.1
 BIVM-ERCC5
 BIVM-ERCC5 readthrough
chr11_+_61197572 0.11 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
 SDHAF2
 succinate dehydrogenase complex assembly factor 2
chr9_+_133539981 0.11 ENST00000253008.2
 PRDM12
 PR domain containing 12
chr8_-_121824374 0.11 ENST00000517992.1
 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr15_-_77712477 0.11 ENST00000560626.2
 PEAK1
 pseudopodium-enriched atypical kinase 1
chr21_+_33671160 0.11 ENST00000303645.5
 MRAP
 melanocortin 2 receptor accessory protein
chr19_+_16059818 0.11 ENST00000322107.1
 OR10H4
 olfactory receptor, family 10, subfamily H, member 4
chr10_+_135050908 0.11 ENST00000325980.9
 VENTX
 VENT homeobox
chr9_-_15510287 0.10 ENST00000397519.2
 PSIP1
 PC4 and SFRS1 interacting protein 1
chr5_-_177207634 0.10 ENST00000513554.1
ENST00000440605.3
 FAM153A
 family with sequence similarity 153, member A
chr14_+_55494323 0.10 ENST00000339298.2
 SOCS4
 suppressor of cytokine signaling 4
chrX_-_103499602 0.09 ENST00000372588.4
 ESX1
 ESX homeobox 1
chr10_+_13141585 0.09 ENST00000378764.2
 OPTN
 optineurin
chr10_-_32667660 0.09 ENST00000375110.2
 EPC1
 enhancer of polycomb homolog 1 (Drosophila)
chr3_-_47555167 0.09 ENST00000296149.4
 ELP6
 elongator acetyltransferase complex subunit 6
chr14_+_55595762 0.09 ENST00000254301.9
 LGALS3
 lectin, galactoside-binding, soluble, 3
chr11_+_94245617 0.09 ENST00000542198.1
 RP11-867G2.2
 long intergenic non-protein coding RNA 1171
chr7_+_7811992 0.09 ENST00000406829.1
 RPA3-AS1
 RPA3 antisense RNA 1
chr3_+_114012819 0.09 ENST00000383671.3
 TIGIT
 T cell immunoreceptor with Ig and ITIM domains
chr15_+_79166065 0.09 ENST00000559690.1
ENST00000559158.1
 MORF4L1
 mortality factor 4 like 1
chr14_+_55493920 0.09 ENST00000395472.2
ENST00000555846.1
 SOCS4
 suppressor of cytokine signaling 4
chr6_+_118869452 0.08 ENST00000357525.5
 PLN
 phospholamban
chr3_+_108308513 0.08 ENST00000361582.3
 DZIP3
 DAZ interacting zinc finger protein 3
chr14_-_75389925 0.08 ENST00000556776.1
 RPS6KL1
 ribosomal protein S6 kinase-like 1
chr20_+_5987890 0.08 ENST00000378868.4
 CRLS1
 cardiolipin synthase 1
chr11_-_66964638 0.08 ENST00000444002.2
 AP001885.1
 AP001885.1
chr15_-_42500351 0.08 ENST00000348544.4
ENST00000318006.5
 VPS39
 vacuolar protein sorting 39 homolog (S. cerevisiae)
chr14_+_55595960 0.08 ENST00000554715.1
 LGALS3
 lectin, galactoside-binding, soluble, 3
chr8_+_28748765 0.07 ENST00000355231.5
 HMBOX1
 homeobox containing 1
chr14_+_22964877 0.07 ENST00000390494.1
 TRAJ43
 T cell receptor alpha joining 43
chr5_-_11588907 0.07 ENST00000513598.1
ENST00000503622.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr12_-_11150474 0.07 ENST00000538986.1
 TAS2R20
 taste receptor, type 2, member 20
chr11_-_114430570 0.07 ENST00000251921.2
 NXPE1
 neurexophilin and PC-esterase domain family, member 1
chr2_+_196313239 0.07 ENST00000413290.1
 AC064834.1
 AC064834.1
chr7_+_23338819 0.07 ENST00000466681.1
 MALSU1
 mitochondrial assembly of ribosomal large subunit 1
chr16_+_69345243 0.07 ENST00000254950.11
 VPS4A
 vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr20_+_34129770 0.07 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
 ERGIC3
 ERGIC and golgi 3
chr15_+_51669444 0.07 ENST00000396399.2
 GLDN
 gliomedin
chr1_+_202091980 0.06 ENST00000367282.5
 GPR37L1
 G protein-coupled receptor 37 like 1
chr4_-_100140331 0.06 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
 ADH6
 alcohol dehydrogenase 6 (class V)
chr13_-_81801115 0.06 ENST00000567258.1
 LINC00564
 long intergenic non-protein coding RNA 564
chr17_-_37934466 0.06 ENST00000583368.1
 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
chr19_-_7812446 0.06 ENST00000394173.4
ENST00000301357.8
 CD209
 CD209 molecule
chr20_+_5731027 0.06 ENST00000378979.4
ENST00000303142.6
 C20orf196
 chromosome 20 open reading frame 196
chr8_+_24241969 0.05 ENST00000522298.1
 ADAMDEC1
 ADAM-like, decysin 1
chr2_-_109605663 0.05 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
 EDAR
 ectodysplasin A receptor
chr3_-_21792838 0.05 ENST00000281523.2
 ZNF385D
 zinc finger protein 385D
chr10_+_135204338 0.05 ENST00000468317.2
 RP11-108K14.8
 Mitochondrial GTPase 1
chr6_-_31830655 0.05 ENST00000375631.4
 NEU1
 sialidase 1 (lysosomal sialidase)
chr6_-_76072719 0.05 ENST00000370020.1
 FILIP1
 filamin A interacting protein 1
chr1_+_160160283 0.05 ENST00000368079.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chr9_+_75229616 0.05 ENST00000340019.3
 TMC1
 transmembrane channel-like 1
chr8_+_24241789 0.05 ENST00000256412.4
ENST00000538205.1
 ADAMDEC1
 ADAM-like, decysin 1
chr1_-_167487808 0.05 ENST00000392122.3
 CD247
 CD247 molecule
chr14_-_101295407 0.05 ENST00000596284.1
 AL117190.2
 AL117190.2
chr21_+_17792672 0.05 ENST00000602620.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr14_+_77582905 0.05 ENST00000557408.1
 TMEM63C
 transmembrane protein 63C
chr1_+_8021954 0.05 ENST00000377491.1
ENST00000377488.1
 PARK7
 parkinson protein 7
chr3_-_93781750 0.04 ENST00000314636.2
 DHFRL1
 dihydrofolate reductase-like 1
chr21_+_33671264 0.04 ENST00000339944.4
 MRAP
 melanocortin 2 receptor accessory protein
chr7_+_107220899 0.04 ENST00000379117.2
ENST00000473124.1
 BCAP29
 B-cell receptor-associated protein 29
chr1_+_160160346 0.04 ENST00000368078.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_-_147162078 0.04 ENST00000507386.1
 JAKMIP2
 janus kinase and microtubule interacting protein 2
chr7_+_99425633 0.04 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
 CYP3A43
 cytochrome P450, family 3, subfamily A, polypeptide 43
chr1_-_167487758 0.04 ENST00000362089.5
 CD247
 CD247 molecule
chr18_+_61637159 0.04 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
 SERPINB8
 serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr9_-_70465758 0.03 ENST00000489273.1
 CBWD5
 COBW domain containing 5
chr11_-_92931098 0.03 ENST00000326402.4
 SLC36A4
 solute carrier family 36 (proton/amino acid symporter), member 4
chr6_-_32908765 0.03 ENST00000416244.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr22_+_41697520 0.03 ENST00000352645.4
 ZC3H7B
 zinc finger CCCH-type containing 7B
chrX_+_11311533 0.03 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
 AMELX
 amelogenin, X-linked
chr1_-_149908217 0.03 ENST00000369140.3
 MTMR11
 myotubularin related protein 11
chr10_-_29923893 0.03 ENST00000355867.4
 SVIL
 supervillin
chr2_-_136288113 0.03 ENST00000401392.1
 ZRANB3
 zinc finger, RAN-binding domain containing 3
chr7_+_138818490 0.03 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
 TTC26
 tetratricopeptide repeat domain 26
chr19_-_20150014 0.03 ENST00000358523.5
ENST00000397162.1
ENST00000601100.1
 ZNF682
 zinc finger protein 682
chr9_+_44868935 0.03 ENST00000448436.2
 RP11-160N1.10
 RP11-160N1.10
chr19_+_55043977 0.02 ENST00000335056.3
 KIR3DX1
 killer cell immunoglobulin-like receptor, three domains, X1
chr9_-_86593238 0.02 ENST00000351839.3
 HNRNPK
 heterogeneous nuclear ribonucleoprotein K
chr1_+_76540386 0.02 ENST00000328299.3
 ST6GALNAC3
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chrX_-_122756660 0.02 ENST00000441692.1
 THOC2
 THO complex 2
chr6_+_108616243 0.02 ENST00000421954.1
 LACE1
 lactation elevated 1
chr3_+_93781728 0.02 ENST00000314622.4
 NSUN3
 NOP2/Sun domain family, member 3
chr11_-_5345582 0.01 ENST00000328813.2
 OR51B2
 olfactory receptor, family 51, subfamily B, member 2
chr19_-_7812397 0.01 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
 CD209
 CD209 molecule
chr11_+_60681346 0.01 ENST00000227525.3
 TMEM109
 transmembrane protein 109
chr13_-_52733980 0.01 ENST00000339406.3
 NEK3
 NIMA-related kinase 3
chr4_+_159442878 0.01 ENST00000307765.5
ENST00000423548.1
 RXFP1
 relaxin/insulin-like family peptide receptor 1
chr8_-_72274095 0.00 ENST00000303824.7
 EYA1
 eyes absent homolog 1 (Drosophila)
chr11_+_92085262 0.00 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
 FAT3
 FAT atypical cadherin 3
chr7_+_2636522 0.00 ENST00000423196.1
 IQCE
 IQ motif containing E
chr4_-_164534657 0.00 ENST00000339875.5
 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr12_-_82752565 0.00 ENST00000256151.7
 CCDC59
 coiled-coil domain containing 59

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.2 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 0.5 GO:0019417 sulfur oxidation(GO:0019417)
0.2 1.0 GO:0008218 bioluminescence(GO:0008218)
0.1 0.5 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.3 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 1.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 2.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.0 GO:1903384 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 3.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 1.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 3.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 2.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection