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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for PBX2

Z-value: 0.09

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Transcription factors associated with PBX2

Gene Symbol Gene ID Gene Info
PBX2
ENSG00000204304.7 PBX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX2hg19_v2_chr6_-_32157947_321579920.611.1e-01Click!

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_28125638 0.08 ENST00000545234.1
 PTHLH
 parathyroid hormone-like hormone
chr12_-_28124903 0.07 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH
 parathyroid hormone-like hormone
chr2_+_234104079 0.06 ENST00000417661.1
 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
chr2_+_113033164 0.05 ENST00000409871.1
ENST00000343936.4
 ZC3H6
 zinc finger CCCH-type containing 6
chr17_-_29624343 0.05 ENST00000247271.4
 OMG
 oligodendrocyte myelin glycoprotein
chr10_-_45474237 0.04 ENST00000448778.1
ENST00000298295.3
 C10orf10
 chromosome 10 open reading frame 10
chr14_-_23624511 0.04 ENST00000529705.2
 SLC7A8
 solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr1_+_62417957 0.04 ENST00000307297.7
ENST00000543708.1
 INADL
 InaD-like (Drosophila)
chr6_+_26045603 0.03 ENST00000540144.1
 HIST1H3C
 histone cluster 1, H3c
chr2_+_234601512 0.03 ENST00000305139.6
 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_+_234602305 0.03 ENST00000406651.1
 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
chr12_-_39734783 0.03 ENST00000552961.1
 KIF21A
 kinesin family member 21A
chr11_-_104769141 0.03 ENST00000508062.1
ENST00000422698.2
 CASP12
 caspase 12 (gene/pseudogene)
chr5_+_54320078 0.03 ENST00000231009.2
 GZMK
 granzyme K (granzyme 3; tryptase II)
chr9_-_128246769 0.03 ENST00000444226.1
 MAPKAP1
 mitogen-activated protein kinase associated protein 1
chr4_+_37962018 0.02 ENST00000504686.1
 PTTG2
 pituitary tumor-transforming 2
chr8_-_6420930 0.02 ENST00000325203.5
 ANGPT2
 angiopoietin 2
chr17_-_29151794 0.02 ENST00000324238.6
 CRLF3
 cytokine receptor-like factor 3
chr16_+_1128781 0.02 ENST00000293897.4
ENST00000562758.1
 SSTR5
 somatostatin receptor 5
chr1_-_39339777 0.02 ENST00000397572.2
 MYCBP
 MYC binding protein
chr2_-_99917639 0.02 ENST00000308528.4
 LYG1
 lysozyme G-like 1
chr11_+_68228186 0.02 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
 PPP6R3
 protein phosphatase 6, regulatory subunit 3
chr1_-_115323245 0.02 ENST00000060969.5
ENST00000369528.5
 SIKE1
 suppressor of IKBKE 1
chr2_+_204732666 0.02 ENST00000295854.6
ENST00000472206.1
 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
chr3_-_52864680 0.02 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
 ITIH4
 inter-alpha-trypsin inhibitor heavy chain family, member 4
chr18_-_72920372 0.01 ENST00000581620.1
ENST00000582437.1
 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
chr14_-_55658252 0.01 ENST00000395425.2
 DLGAP5
 discs, large (Drosophila) homolog-associated protein 5
chr12_+_53835539 0.01 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
 PRR13
 proline rich 13
chr17_+_8191815 0.01 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
 RANGRF
 RAN guanine nucleotide release factor
chr14_+_27342334 0.01 ENST00000548170.1
ENST00000552926.1
 RP11-384J4.1
 RP11-384J4.1
chr11_+_62432777 0.01 ENST00000532971.1
 METTL12
 methyltransferase like 12
chr5_-_75008244 0.01 ENST00000510798.1
ENST00000446329.2
 POC5
 POC5 centriolar protein
chr6_+_160211481 0.01 ENST00000367034.4
 MRPL18
 mitochondrial ribosomal protein L18
chr11_-_62432641 0.01 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
 RP11-831H9.11
C11orf48
 Uncharacterized protein
chromosome 11 open reading frame 48
chr12_+_53835383 0.01 ENST00000429243.2
 PRR13
 proline rich 13
chr3_+_188889737 0.01 ENST00000345063.3
 TPRG1
 tumor protein p63 regulated 1
chr2_+_33661382 0.01 ENST00000402538.3
 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_-_55658323 0.01 ENST00000554067.1
ENST00000247191.2
 DLGAP5
 discs, large (Drosophila) homolog-associated protein 5
chr1_+_101702417 0.01 ENST00000305352.6
 S1PR1
 sphingosine-1-phosphate receptor 1
chr2_+_204732487 0.00 ENST00000302823.3
 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
chr2_+_12857015 0.00 ENST00000155926.4
 TRIB2
 tribbles pseudokinase 2
chr22_+_42017987 0.00 ENST00000405506.1
 XRCC6
 X-ray repair complementing defective repair in Chinese hamster cells 6
chr2_-_31440377 0.00 ENST00000444918.2
ENST00000403897.3
 CAPN14
 calpain 14
chr2_+_12857043 0.00 ENST00000381465.2
 TRIB2
 tribbles pseudokinase 2
chr20_+_238357 0.00 ENST00000382376.3
 DEFB132
 defensin, beta 132
chr7_-_32529973 0.00 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
 LSM5
 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_-_11492366 0.00 ENST00000595360.1
 CTD-3088G3.8
 Protein LOC388210
chrX_+_46696372 0.00 ENST00000218340.3
 RP2
 retinitis pigmentosa 2 (X-linked recessive)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)