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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for PGR

Z-value: 0.94

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
PGR
ENSG00000082175.10 PGR

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg19_v2_chr11_-_100999775_100999801,
hg19_v2_chr11_-_101000445_101000465		0.324.4e-01Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_102104980 3.17 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr13_+_102104952 2.85 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr3_-_114343768 1.20 ENST00000393785.2
 ZBTB20
 zinc finger and BTB domain containing 20
chr2_-_190044480 1.16 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr10_+_69865866 1.13 ENST00000354393.2
 MYPN
 myopalladin
chrX_+_16964985 1.09 ENST00000303843.7
 REPS2
 RALBP1 associated Eps domain containing 2
chr4_+_14113592 0.97 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
 LINC01085
 long intergenic non-protein coding RNA 1085
chr14_-_61124977 0.86 ENST00000554986.1
 SIX1
 SIX homeobox 1
chr3_-_114035026 0.77 ENST00000570269.1
 RP11-553L6.5
 RP11-553L6.5
chr16_-_3350614 0.74 ENST00000268674.2
 TIGD7
 tigger transposable element derived 7
chr3_-_114343039 0.67 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr6_+_72926145 0.67 ENST00000425662.2
ENST00000453976.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr1_-_85870177 0.66 ENST00000542148.1
 DDAH1
 dimethylarginine dimethylaminohydrolase 1
chr13_+_32838801 0.65 ENST00000542859.1
 FRY
 furry homolog (Drosophila)
chr1_+_155829286 0.65 ENST00000368324.4
 SYT11
 synaptotagmin XI
chr3_-_58563094 0.58 ENST00000464064.1
 FAM107A
 family with sequence similarity 107, member A
chr1_-_145039835 0.58 ENST00000533259.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr5_+_67584174 0.58 ENST00000320694.8
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr2_-_175711133 0.57 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr7_-_150946015 0.56 ENST00000262188.8
 SMARCD3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr10_-_49482907 0.54 ENST00000374201.3
ENST00000407470.4
 FRMPD2
 FERM and PDZ domain containing 2
chr12_-_91505608 0.52 ENST00000266718.4
 LUM
 lumican
chr6_-_43276535 0.51 ENST00000372569.3
ENST00000274990.4
 CRIP3
 cysteine-rich protein 3
chrX_+_54834159 0.51 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
 MAGED2
 melanoma antigen family D, 2
chr10_-_28571015 0.51 ENST00000375719.3
ENST00000375732.1
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_88974236 0.50 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
 KITLG
 KIT ligand
chr6_-_154831779 0.49 ENST00000607772.1
 CNKSR3
 CNKSR family member 3
chr5_-_121413974 0.49 ENST00000231004.4
 LOX
 lysyl oxidase
chr16_+_86600857 0.48 ENST00000320354.4
 FOXC2
 forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr1_+_78470530 0.46 ENST00000370763.5
 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
chrX_+_54834004 0.45 ENST00000375068.1
 MAGED2
 melanoma antigen family D, 2
chr12_+_79258547 0.44 ENST00000457153.2
 SYT1
 synaptotagmin I
chrX_+_57618269 0.44 ENST00000374888.1
 ZXDB
 zinc finger, X-linked, duplicated B
chr11_+_20044600 0.43 ENST00000311043.8
 NAV2
 neuron navigator 2
chr1_-_145039949 0.42 ENST00000313382.9
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr19_+_30863271 0.42 ENST00000355537.3
 ZNF536
 zinc finger protein 536
chr20_+_23420322 0.41 ENST00000347397.1
 CSTL1
 cystatin-like 1
chr5_-_124081008 0.40 ENST00000306315.5
 ZNF608
 zinc finger protein 608
chr20_+_23420885 0.39 ENST00000246020.2
 CSTL1
 cystatin-like 1
chr3_+_29323043 0.38 ENST00000452462.1
ENST00000456853.1
 RBMS3
 RNA binding motif, single stranded interacting protein 3
chr10_+_104178946 0.38 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr8_-_7220490 0.37 ENST00000400078.2
 ZNF705G
 zinc finger protein 705G
chr14_-_35182994 0.36 ENST00000341223.3
 CFL2
 cofilin 2 (muscle)
chr1_+_192778161 0.36 ENST00000235382.5
 RGS2
 regulator of G-protein signaling 2, 24kDa
chr5_+_137419581 0.36 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
 WNT8A
 wingless-type MMTV integration site family, member 8A
chr1_-_156828810 0.36 ENST00000368195.3
 INSRR
 insulin receptor-related receptor
chr2_+_10560147 0.35 ENST00000422133.1
 HPCAL1
 hippocalcin-like 1
chr5_-_160279207 0.35 ENST00000327245.5
 ATP10B
 ATPase, class V, type 10B
chr17_-_56621665 0.34 ENST00000321691.3
 C17orf47
 chromosome 17 open reading frame 47
chr5_+_139505520 0.34 ENST00000333305.3
 IGIP
 IgA-inducing protein
chr3_-_49722523 0.34 ENST00000448220.1
 MST1
 macrophage stimulating 1 (hepatocyte growth factor-like)
chr15_+_31658349 0.33 ENST00000558844.1
 KLF13
 Kruppel-like factor 13
chr5_+_133861790 0.33 ENST00000395003.1
 PHF15
 jade family PHD finger 2
chr16_-_66952779 0.33 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
 CDH16
 cadherin 16, KSP-cadherin
chr1_-_179834311 0.33 ENST00000553856.1
 IFRG15
 Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr16_-_66952742 0.32 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
 CDH16
 cadherin 16, KSP-cadherin
chr7_+_130126012 0.31 ENST00000341441.5
 MEST
 mesoderm specific transcript
chr9_+_82188077 0.30 ENST00000425506.1
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_-_14026063 0.29 ENST00000443608.1
ENST00000438956.1
 ETV1
 ets variant 1
chr19_-_10446449 0.29 ENST00000592439.1
 ICAM3
 intercellular adhesion molecule 3
chr14_-_107219365 0.29 ENST00000424969.2
 IGHV3-74
 immunoglobulin heavy variable 3-74
chr12_-_71551652 0.28 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr18_+_6729698 0.27 ENST00000383472.4
 ARHGAP28
 Rho GTPase activating protein 28
chr22_+_38219389 0.27 ENST00000249041.2
 GALR3
 galanin receptor 3
chr4_+_15004165 0.27 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
 CPEB2
 cytoplasmic polyadenylation element binding protein 2
chr15_+_93447675 0.27 ENST00000536619.1
 CHD2
 chromodomain helicase DNA binding protein 2
chr2_-_220034745 0.26 ENST00000455516.2
ENST00000396775.3
ENST00000295738.7
 SLC23A3
 solute carrier family 23, member 3
chr19_-_48059113 0.26 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
 ZNF541
 zinc finger protein 541
chr7_+_73442422 0.26 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
 ELN
 elastin
chr5_+_133842243 0.26 ENST00000515627.2
 AC005355.2
 AC005355.2
chr17_-_15168624 0.26 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
 PMP22
 peripheral myelin protein 22
chr7_-_14026123 0.26 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
 ETV1
 ets variant 1
chr9_-_113761720 0.25 ENST00000541779.1
ENST00000374430.2
 LPAR1
 lysophosphatidic acid receptor 1
chr7_+_73442487 0.25 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
 ELN
 elastin
chr6_-_24489842 0.25 ENST00000230036.1
 GPLD1
 glycosylphosphatidylinositol specific phospholipase D1
chr9_+_127615733 0.25 ENST00000373574.1
 WDR38
 WD repeat domain 38
chr1_-_32210275 0.25 ENST00000440175.2
 BAI2
 brain-specific angiogenesis inhibitor 2
chr11_-_73693875 0.25 ENST00000536983.1
 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_85641162 0.25 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
 CAPG
 capping protein (actin filament), gelsolin-like
chr19_+_41119323 0.25 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
 LTBP4
 latent transforming growth factor beta binding protein 4
chr3_-_151102529 0.25 ENST00000302632.3
 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
chr3_+_42695176 0.25 ENST00000232974.6
ENST00000457842.3
 ZBTB47
 zinc finger and BTB domain containing 47
chr21_+_17566643 0.24 ENST00000419952.1
ENST00000445461.2
 LINC00478
 long intergenic non-protein coding RNA 478
chr10_+_124030819 0.24 ENST00000260723.4
ENST00000368994.2
 BTBD16
 BTB (POZ) domain containing 16
chr1_+_154975258 0.23 ENST00000417934.2
 ZBTB7B
 zinc finger and BTB domain containing 7B
chr7_+_73442457 0.23 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
 ELN
 elastin
chr2_-_183387430 0.23 ENST00000410103.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr6_+_39760129 0.23 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr22_-_31688381 0.23 ENST00000487265.2
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr7_-_23510086 0.22 ENST00000258729.3
 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
chr9_-_73736511 0.22 ENST00000377110.3
ENST00000377111.2
 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
chr2_-_27531313 0.22 ENST00000296099.2
 UCN
 urocortin
chr7_+_130126165 0.21 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
 MEST
 mesoderm specific transcript
chr12_+_56661461 0.21 ENST00000546544.1
ENST00000553234.1
 COQ10A
 coenzyme Q10 homolog A (S. cerevisiae)
chr9_-_131940526 0.21 ENST00000372491.2
 IER5L
 immediate early response 5-like
chr9_-_34665983 0.20 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
 RP11-195F19.5
 HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr11_+_6502675 0.19 ENST00000254616.6
ENST00000530751.1
 TIMM10B
 translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr2_-_216300784 0.19 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
 FN1
 fibronectin 1
chr22_-_30162924 0.19 ENST00000344318.3
ENST00000397781.3
 ZMAT5
 zinc finger, matrin-type 5
chr9_+_131683174 0.19 ENST00000372592.3
ENST00000428610.1
 PHYHD1
 phytanoyl-CoA dioxygenase domain containing 1
chrX_+_135570046 0.19 ENST00000370648.3
 BRS3
 bombesin-like receptor 3
chr2_+_42104692 0.19 ENST00000398796.2
ENST00000442214.1
 AC104654.1
 AC104654.1
chr3_+_137906109 0.19 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
 ARMC8
 armadillo repeat containing 8
chr17_+_57642886 0.19 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
 DHX40
 DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr7_+_30960915 0.19 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
 AQP1
 aquaporin 1 (Colton blood group)
chr5_+_102201430 0.19 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr2_-_179315786 0.19 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
chr13_+_24144509 0.18 ENST00000248484.4
 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
chr15_+_94899183 0.18 ENST00000557742.1
 MCTP2
 multiple C2 domains, transmembrane 2
chr9_-_15510989 0.18 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
 PSIP1
 PC4 and SFRS1 interacting protein 1
chr1_-_110933663 0.18 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
 SLC16A4
 solute carrier family 16, member 4
chr1_-_167906277 0.18 ENST00000271373.4
 MPC2
 mitochondrial pyruvate carrier 2
chr6_+_63921399 0.18 ENST00000356170.3
 FKBP1C
 FK506 binding protein 1C
chr2_-_220034712 0.18 ENST00000409370.2
ENST00000430764.1
ENST00000409878.3
 SLC23A3
 solute carrier family 23, member 3
chr2_-_158300556 0.18 ENST00000264192.3
 CYTIP
 cytohesin 1 interacting protein
chr6_+_108487245 0.18 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chr17_-_40540586 0.18 ENST00000264657.5
 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
chr19_+_13135790 0.18 ENST00000358552.3
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr6_-_150212029 0.17 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
 RAET1E
 retinoic acid early transcript 1E
chr5_-_138718973 0.17 ENST00000353963.3
ENST00000348729.3
 SLC23A1
 solute carrier family 23 (ascorbic acid transporter), member 1
chr13_+_49822041 0.17 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
 CDADC1
 cytidine and dCMP deaminase domain containing 1
chr17_+_45286387 0.16 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
chr3_-_52001448 0.16 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
 PCBP4
 poly(rC) binding protein 4
chr17_+_45286706 0.16 ENST00000393450.1
ENST00000572303.1
 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
chr2_-_188312971 0.16 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
 CALCRL
 calcitonin receptor-like
chr2_-_179315453 0.16 ENST00000432031.2
 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
chr10_-_48416849 0.16 ENST00000249598.1
 GDF2
 growth differentiation factor 2
chr7_+_22766766 0.16 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
 IL6
 interleukin 6 (interferon, beta 2)
chr3_+_52454971 0.16 ENST00000465863.1
 PHF7
 PHD finger protein 7
chr11_-_124806297 0.16 ENST00000298251.4
 HEPACAM
 hepatic and glial cell adhesion molecule
chr3_+_158991025 0.16 ENST00000337808.6
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr18_+_43304092 0.16 ENST00000321925.4
ENST00000587601.1
 SLC14A1
 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr5_+_102201509 0.15 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase
chrX_-_69509738 0.15 ENST00000374454.1
ENST00000239666.4
 PDZD11
 PDZ domain containing 11
chr14_-_106692191 0.15 ENST00000390607.2
 IGHV3-21
 immunoglobulin heavy variable 3-21
chr2_-_219925189 0.15 ENST00000295731.6
 IHH
 indian hedgehog
chr1_-_154943002 0.15 ENST00000606391.1
 SHC1
 SHC (Src homology 2 domain containing) transforming protein 1
chrX_+_106163626 0.15 ENST00000336803.1
 CLDN2
 claudin 2
chr1_-_154943212 0.15 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
 SHC1
 SHC (Src homology 2 domain containing) transforming protein 1
chr19_+_507299 0.15 ENST00000359315.5
 TPGS1
 tubulin polyglutamylase complex subunit 1
chr19_-_36247910 0.15 ENST00000587965.1
ENST00000004982.3
 HSPB6
 heat shock protein, alpha-crystallin-related, B6
chr10_-_104178857 0.15 ENST00000020673.5
 PSD
 pleckstrin and Sec7 domain containing
chr5_-_131347501 0.14 ENST00000543479.1
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chr15_+_54305101 0.14 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
 UNC13C
 unc-13 homolog C (C. elegans)
chr17_-_2966901 0.14 ENST00000575751.1
 OR1D5
 olfactory receptor, family 1, subfamily D, member 5
chr21_+_17791648 0.14 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
 LINC00478
 long intergenic non-protein coding RNA 478
chr8_+_9953214 0.14 ENST00000382490.5
 MSRA
 methionine sulfoxide reductase A
chr2_-_179315490 0.14 ENST00000487082.1
 PRKRA
 protein kinase, interferon-inducible double stranded RNA dependent activator
chr4_+_146539415 0.14 ENST00000281317.5
 MMAA
 methylmalonic aciduria (cobalamin deficiency) cblA type
chr22_-_31688431 0.14 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr1_+_145516560 0.14 ENST00000537888.1
 PEX11B
 peroxisomal biogenesis factor 11 beta
chrX_+_100743031 0.14 ENST00000423738.3
 ARMCX4
 armadillo repeat containing, X-linked 4
chrX_-_114953669 0.14 ENST00000449327.1
 RP1-241P17.4
 Uncharacterized protein
chr17_+_75447326 0.14 ENST00000591088.1
 SEPT9
 septin 9
chr6_-_43021437 0.14 ENST00000265348.3
 CUL7
 cullin 7
chr1_-_145039771 0.13 ENST00000493130.2
ENST00000532801.1
ENST00000478649.2
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr5_+_140797296 0.13 ENST00000398594.2
 PCDHGB7
 protocadherin gamma subfamily B, 7
chr2_-_163695128 0.13 ENST00000332142.5
 KCNH7
 potassium voltage-gated channel, subfamily H (eag-related), member 7
chr18_+_13611763 0.13 ENST00000585931.1
 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
chr20_+_46130619 0.13 ENST00000372004.3
 NCOA3
 nuclear receptor coactivator 3
chr8_-_42623747 0.13 ENST00000534622.1
 CHRNA6
 cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr9_-_215744 0.13 ENST00000382387.2
 C9orf66
 chromosome 9 open reading frame 66
chr17_+_73997796 0.13 ENST00000586261.1
 CDK3
 cyclin-dependent kinase 3
chr1_+_155146318 0.13 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
 TRIM46
 tripartite motif containing 46
chr12_-_53901266 0.13 ENST00000609999.1
ENST00000267017.3
 NPFF
 neuropeptide FF-amide peptide precursor
chr3_+_185046676 0.13 ENST00000428617.1
ENST00000443863.1
 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
chr9_+_2159850 0.13 ENST00000416751.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_154164534 0.13 ENST00000271850.7
ENST00000368530.2
 TPM3
 tropomyosin 3
chr18_+_6729725 0.12 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
 ARHGAP28
 Rho GTPase activating protein 28
chr17_-_42988004 0.12 ENST00000586125.1
ENST00000591880.1
 GFAP
 glial fibrillary acidic protein
chr7_+_73442102 0.12 ENST00000445912.1
ENST00000252034.7
 ELN
 elastin
chr6_-_88299678 0.12 ENST00000369536.5
 RARS2
 arginyl-tRNA synthetase 2, mitochondrial
chr3_+_44626446 0.12 ENST00000441021.1
ENST00000322734.2
 ZNF660
 zinc finger protein 660
chr4_-_152149033 0.11 ENST00000514152.1
 SH3D19
 SH3 domain containing 19
chr11_-_615570 0.11 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
 IRF7
 interferon regulatory factor 7
chr11_-_6502534 0.11 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
 ARFIP2
 ADP-ribosylation factor interacting protein 2
chr17_+_37824411 0.11 ENST00000269582.2
 PNMT
 phenylethanolamine N-methyltransferase
chr17_+_46970134 0.11 ENST00000503641.1
ENST00000514808.1
 ATP5G1
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_+_13135386 0.11 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_75379612 0.11 ENST00000526740.1
 MAP6
 microtubule-associated protein 6
chr5_-_131347583 0.11 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chr13_-_103053946 0.11 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr4_-_154710210 0.11 ENST00000274063.4
 SFRP2
 secreted frizzled-related protein 2
chr7_+_134576151 0.11 ENST00000393118.2
 CALD1
 caldesmon 1
chr13_+_43148281 0.11 ENST00000239849.6
ENST00000398795.2
ENST00000544862.1
 TNFSF11
 tumor necrosis factor (ligand) superfamily, member 11
chr20_-_44168046 0.11 ENST00000372665.3
ENST00000372670.3
ENST00000600168.1
 WFDC6
 WAP four-disulfide core domain 6
chr11_-_6502580 0.11 ENST00000423813.2
ENST00000396777.3
 ARFIP2
 ADP-ribosylation factor interacting protein 2
chr15_+_67841330 0.11 ENST00000354498.5
 MAP2K5
 mitogen-activated protein kinase kinase 5
chr1_-_115292591 0.11 ENST00000438362.2
 CSDE1
 cold shock domain containing E1, RNA-binding
chr1_+_153232160 0.11 ENST00000368742.3
 LOR
 loricrin
chr2_+_9778872 0.10 ENST00000478468.1
 RP11-521D12.1
 RP11-521D12.1
chr12_+_53848505 0.10 ENST00000552819.1
ENST00000455667.3
 PCBP2
 poly(rC) binding protein 2
chrX_-_21776281 0.10 ENST00000379494.3
 SMPX
 small muscle protein, X-linked
chr9_+_71394945 0.10 ENST00000394264.3
 FAM122A
 family with sequence similarity 122A
chr17_-_76183111 0.10 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
 TK1
 thymidine kinase 1, soluble
chr19_+_44488330 0.10 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
 ZNF155
 zinc finger protein 155
chr5_+_102201687 0.10 ENST00000304400.7
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr6_-_76782371 0.10 ENST00000369950.3
ENST00000369963.3
 IMPG1
 interphotoreceptor matrix proteoglycan 1
chr8_+_10530155 0.10 ENST00000521818.1
 C8orf74
 chromosome 8 open reading frame 74
chr17_+_46970178 0.10 ENST00000393366.2
ENST00000506855.1
 ATP5G1
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:1905154 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 0.9 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.5 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 0.5 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 0.2 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1 0.3 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.2 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:0070837 L-ascorbic acid transport(GO:0015882) dehydroascorbic acid transport(GO:0070837) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.1 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.4 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519)
0.0 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0100009 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.0 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:1904124 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.6 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0018095 sperm axoneme assembly(GO:0007288) protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.0 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.6 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.2 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.2 GO:0033300 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) dehydroascorbic acid transporter activity(GO:0033300) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors