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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for POU2F2_POU3F1

Z-value: 0.63

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
POU2F2
ENSG00000028277.16 POU2F2
POU3F1
ENSG00000185668.5 POU3F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636617_426366320.571.4e-01Click!
POU3F1hg19_v2_chr1_-_38512450_38512474-0.285.0e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_26124373 1.50 ENST00000377791.2
ENST00000602637.1
 HIST1H2AC
 histone cluster 1, H2ac
chrX_-_24665208 1.26 ENST00000356768.4
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr5_+_36608422 1.11 ENST00000381918.3
 SLC1A3
 solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_140196703 0.88 ENST00000356628.2
 NRARP
 NOTCH-regulated ankyrin repeat protein
chrX_-_24665353 0.73 ENST00000379144.2
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr18_-_53089723 0.72 ENST00000561992.1
ENST00000562512.2
 TCF4
 transcription factor 4
chr12_+_113344755 0.65 ENST00000550883.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_+_37137939 0.65 ENST00000373509.5
 PIM1
 pim-1 oncogene
chr6_+_26251835 0.61 ENST00000356350.2
 HIST1H2BH
 histone cluster 1, H2bh
chr12_-_31479045 0.61 ENST00000539409.1
ENST00000395766.1
 FAM60A
 family with sequence similarity 60, member A
chr7_+_16793160 0.60 ENST00000262067.4
 TSPAN13
 tetraspanin 13
chr1_+_149822620 0.59 ENST00000369159.2
 HIST2H2AA4
 histone cluster 2, H2aa4
chr17_-_47841485 0.59 ENST00000506156.1
ENST00000240364.2
 FAM117A
 family with sequence similarity 117, member A
chr6_-_27114577 0.58 ENST00000356950.1
ENST00000396891.4
 HIST1H2BK
 histone cluster 1, H2bk
chr6_-_26124138 0.58 ENST00000314332.5
ENST00000396984.1
 HIST1H2BC
 histone cluster 1, H2bc
chr6_+_26183958 0.58 ENST00000356530.3
 HIST1H2BE
 histone cluster 1, H2be
chr14_-_106622419 0.58 ENST00000390604.2
 IGHV3-16
 immunoglobulin heavy variable 3-16 (non-functional)
chr6_-_11779014 0.58 ENST00000229583.5
 ADTRP
 androgen-dependent TFPI-regulating protein
chr16_-_30107491 0.58 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
 YPEL3
 yippee-like 3 (Drosophila)
chr19_-_50143452 0.56 ENST00000246792.3
 RRAS
 related RAS viral (r-ras) oncogene homolog
chr6_-_11779403 0.55 ENST00000414691.3
 ADTRP
 androgen-dependent TFPI-regulating protein
chr10_-_98031265 0.55 ENST00000224337.5
ENST00000371176.2
 BLNK
 B-cell linker
chr10_-_10836865 0.54 ENST00000446372.2
 SFTA1P
 surfactant associated 1, pseudogene
chr6_-_27100529 0.54 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
 HIST1H2BJ
 histone cluster 1, H2bj
chr14_-_106845789 0.53 ENST00000390617.2
 IGHV3-35
 immunoglobulin heavy variable 3-35 (non-functional)
chr22_+_32750872 0.53 ENST00000397468.1
 RFPL3
 ret finger protein-like 3
chr10_-_10836919 0.52 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
 SFTA1P
 surfactant associated 1, pseudogene
chr1_-_149814478 0.52 ENST00000369161.3
 HIST2H2AA3
 histone cluster 2, H2aa3
chr1_-_149858227 0.50 ENST00000369155.2
 HIST2H2BE
 histone cluster 2, H2be
chr16_-_33647696 0.49 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9
 Uncharacterized protein
chr19_+_17858509 0.49 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
 FCHO1
 FCH domain only 1
chr10_-_98031310 0.49 ENST00000427367.2
ENST00000413476.2
 BLNK
 B-cell linker
chr9_-_124991124 0.46 ENST00000394319.4
ENST00000340587.3
 LHX6
 LIM homeobox 6
chr16_+_33020496 0.46 ENST00000565407.2
 IGHV3OR16-8
 immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr12_-_31479107 0.45 ENST00000542983.1
 FAM60A
 family with sequence similarity 60, member A
chr5_+_145317356 0.45 ENST00000511217.1
 SH3RF2
 SH3 domain containing ring finger 2
chr14_-_106610852 0.45 ENST00000390603.2
 IGHV3-15
 immunoglobulin heavy variable 3-15
chr16_+_23847267 0.45 ENST00000321728.7
 PRKCB
 protein kinase C, beta
chr14_-_34420259 0.44 ENST00000250457.3
ENST00000547327.2
 EGLN3
 egl-9 family hypoxia-inducible factor 3
chr1_+_206730484 0.43 ENST00000304534.8
 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
chr2_+_207804278 0.41 ENST00000272852.3
 CPO
 carboxypeptidase O
chr22_-_27456361 0.41 ENST00000453934.1
 CTA-992D9.6
 CTA-992D9.6
chr4_-_186733363 0.40 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2
chr12_+_113344811 0.39 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_-_23886285 0.38 ENST00000374561.5
 ID3
 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr22_+_23046750 0.38 ENST00000390307.2
 IGLV3-22
 immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr18_-_52989217 0.38 ENST00000570287.2
 TCF4
 transcription factor 4
chr2_+_68962014 0.37 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr1_+_156119466 0.37 ENST00000414683.1
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_99797522 0.36 ENST00000389677.5
 FAXC
 failed axon connections homolog (Drosophila)
chr9_-_124990680 0.36 ENST00000541397.2
ENST00000560485.1
 LHX6
 LIM homeobox 6
chrX_+_69674943 0.36 ENST00000542398.1
 DLG3
 discs, large homolog 3 (Drosophila)
chr17_-_19015945 0.35 ENST00000573866.2
 SNORD3D
 small nucleolar RNA, C/D box 3D
chr18_-_52989525 0.35 ENST00000457482.3
 TCF4
 transcription factor 4
chr6_+_27215471 0.34 ENST00000421826.2
 PRSS16
 protease, serine, 16 (thymus)
chr6_+_27215494 0.34 ENST00000230582.3
 PRSS16
 protease, serine, 16 (thymus)
chr7_-_41742697 0.34 ENST00000242208.4
 INHBA
 inhibin, beta A
chr6_-_10415470 0.34 ENST00000379604.2
ENST00000379613.3
 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr14_+_65007177 0.34 ENST00000247207.6
 HSPA2
 heat shock 70kDa protein 2
chr19_-_1132207 0.33 ENST00000438103.2
 SBNO2
 strawberry notch homolog 2 (Drosophila)
chr1_-_149783914 0.32 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
 HIST2H2BF
 histone cluster 2, H2bf
chrX_-_117119243 0.32 ENST00000539496.1
ENST00000469946.1
 KLHL13
 kelch-like family member 13
chr14_-_107013465 0.31 ENST00000390625.2
 IGHV3-49
 immunoglobulin heavy variable 3-49
chr8_+_56792355 0.31 ENST00000519728.1
 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr8_+_56792377 0.30 ENST00000520220.2
 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_-_11779840 0.28 ENST00000506810.1
 ADTRP
 androgen-dependent TFPI-regulating protein
chr1_+_156119798 0.28 ENST00000355014.2
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_+_18535786 0.28 ENST00000406072.1
 HDAC9
 histone deacetylase 9
chr11_-_94964354 0.28 ENST00000536441.1
 SESN3
 sestrin 3
chr12_-_57328187 0.27 ENST00000293502.1
 SDR9C7
 short chain dehydrogenase/reductase family 9C, member 7
chr17_+_73521763 0.26 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
 LLGL2
 lethal giant larvae homolog 2 (Drosophila)
chr12_+_107712173 0.26 ENST00000280758.5
ENST00000420571.2
 BTBD11
 BTB (POZ) domain containing 11
chr12_+_113344582 0.26 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_-_7307358 0.26 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
 TMEM256
TMEM256-PLSCR3
 transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr3_+_151591422 0.26 ENST00000362032.5
 SUCNR1
 succinate receptor 1
chr1_+_6052700 0.25 ENST00000378092.1
ENST00000445501.1
 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_+_3572758 0.25 ENST00000416526.1
 HMG20B
 high mobility group 20B
chr2_+_90108504 0.25 ENST00000390271.2
 IGKV6D-41
 immunoglobulin kappa variable 6D-41 (non-functional)
chr10_+_106113515 0.25 ENST00000369704.3
ENST00000312902.5
 CCDC147
 coiled-coil domain containing 147
chr17_-_56494713 0.25 ENST00000407977.2
 RNF43
 ring finger protein 43
chr6_+_26158343 0.25 ENST00000377777.4
ENST00000289316.2
 HIST1H2BD
 histone cluster 1, H2bd
chr17_-_56494908 0.25 ENST00000577716.1
 RNF43
 ring finger protein 43
chr17_-_56494882 0.25 ENST00000584437.1
 RNF43
 ring finger protein 43
chr11_+_64085560 0.25 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
 PRDX5
 peroxiredoxin 5
chr18_-_61311485 0.24 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
 SERPINB4
 serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr6_+_27114861 0.24 ENST00000377459.1
 HIST1H2AH
 histone cluster 1, H2ah
chr11_-_64085533 0.24 ENST00000544844.1
 TRMT112
 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr2_+_90060377 0.24 ENST00000436451.2
 IGKV6D-21
 immunoglobulin kappa variable 6D-21 (non-functional)
chr14_-_72458326 0.24 ENST00000542853.1
 AC005477.1
 AC005477.1
chr6_-_10415218 0.23 ENST00000466073.1
ENST00000498450.1
 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_+_17337406 0.23 ENST00000597836.1
 OCEL1
 occludin/ELL domain containing 1
chr6_+_26273144 0.23 ENST00000377733.2
 HIST1H2BI
 histone cluster 1, H2bi
chr22_-_29107919 0.23 ENST00000434810.1
ENST00000456369.1
 CHEK2
 checkpoint kinase 2
chr12_-_7245125 0.22 ENST00000542285.1
ENST00000540610.1
 C1R
 complement component 1, r subcomponent
chr8_+_19796381 0.22 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
 LPL
 lipoprotein lipase
chr1_-_94586651 0.22 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr17_+_19091325 0.22 ENST00000584923.1
 SNORD3A
 small nucleolar RNA, C/D box 3A
chr3_+_50192499 0.22 ENST00000413852.1
 SEMA3F
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_-_165555200 0.22 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
 BCHE
 butyrylcholinesterase
chr3_+_50192537 0.22 ENST00000002829.3
 SEMA3F
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_+_17337007 0.22 ENST00000215061.4
 OCEL1
 occludin/ELL domain containing 1
chr19_+_17337473 0.21 ENST00000598068.1
 OCEL1
 occludin/ELL domain containing 1
chr17_-_46894576 0.21 ENST00000393382.3
 TTLL6
 tubulin tyrosine ligase-like family, member 6
chr1_+_167298281 0.21 ENST00000367862.5
 POU2F1
 POU class 2 homeobox 1
chr14_-_106552755 0.21 ENST00000390600.2
 IGHV3-9
 immunoglobulin heavy variable 3-9
chr4_-_47983519 0.21 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1
 cyclic nucleotide gated channel alpha 1
chr11_-_64084959 0.21 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
 TRMT112
 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chrX_+_38660682 0.21 ENST00000457894.1
 MID1IP1
 MID1 interacting protein 1
chr18_-_74839891 0.21 ENST00000581878.1
 MBP
 myelin basic protein
chr3_-_126327398 0.21 ENST00000383572.2
 TXNRD3NB
 thioredoxin reductase 3 neighbor
chr6_-_52628271 0.21 ENST00000493422.1
 GSTA2
 glutathione S-transferase alpha 2
chr11_-_62369291 0.20 ENST00000278823.2
 MTA2
 metastasis associated 1 family, member 2
chr19_+_17337027 0.20 ENST00000601529.1
ENST00000600232.1
 OCEL1
 occludin/ELL domain containing 1
chr2_-_89459813 0.19 ENST00000390256.2
 IGKV6-21
 immunoglobulin kappa variable 6-21 (non-functional)
chr2_+_90211643 0.19 ENST00000390277.2
 IGKV3D-11
 immunoglobulin kappa variable 3D-11
chr1_+_81771806 0.19 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr9_-_116065551 0.18 ENST00000297894.5
 RNF183
 ring finger protein 183
chr19_-_19281054 0.18 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
 MEF2B
 myocyte enhancer factor 2B
chr1_+_17575584 0.18 ENST00000375460.3
 PADI3
 peptidyl arginine deiminase, type III
chr4_-_40517984 0.18 ENST00000381795.6
 RBM47
 RNA binding motif protein 47
chr6_+_27861190 0.18 ENST00000303806.4
 HIST1H2BO
 histone cluster 1, H2bo
chrX_+_38660704 0.17 ENST00000378474.3
 MID1IP1
 MID1 interacting protein 1
chr12_-_11062161 0.17 ENST00000390677.2
 TAS2R13
 taste receptor, type 2, member 13
chr1_-_153044083 0.17 ENST00000341611.2
 SPRR2B
 small proline-rich protein 2B
chr6_-_82462425 0.17 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
 FAM46A
 family with sequence similarity 46, member A
chr6_-_27775694 0.17 ENST00000377401.2
 HIST1H2BL
 histone cluster 1, H2bl
chr2_+_202047596 0.17 ENST00000286186.6
ENST00000360132.3
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr10_+_24528108 0.17 ENST00000438429.1
 KIAA1217
 KIAA1217
chr15_+_52155001 0.17 ENST00000544199.1
 TMOD3
 tropomodulin 3 (ubiquitous)
chr19_-_44123734 0.16 ENST00000598676.1
 ZNF428
 zinc finger protein 428
chr7_+_16566449 0.16 ENST00000401542.2
 LRRC72
 leucine rich repeat containing 72
chr9_+_136325089 0.16 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
 CACFD1
 calcium channel flower domain containing 1
chr4_+_5527117 0.16 ENST00000505296.1
 C4orf6
 chromosome 4 open reading frame 6
chr6_-_143266297 0.16 ENST00000367603.2
 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
chr15_+_65337708 0.16 ENST00000334287.2
 SLC51B
 solute carrier family 51, beta subunit
chr7_-_141673573 0.16 ENST00000547270.1
 TAS2R38
 taste receptor, type 2, member 38
chr6_+_27775899 0.16 ENST00000358739.3
 HIST1H2AI
 histone cluster 1, H2ai
chr4_+_5526883 0.16 ENST00000195455.2
 C4orf6
 chromosome 4 open reading frame 6
chr11_-_75917569 0.16 ENST00000322563.3
 WNT11
 wingless-type MMTV integration site family, member 11
chr2_-_89327228 0.16 ENST00000483158.1
 IGKV3-11
 immunoglobulin kappa variable 3-11
chr7_-_100183742 0.16 ENST00000310300.6
 LRCH4
 leucine-rich repeats and calponin homology (CH) domain containing 4
chr15_+_45406519 0.16 ENST00000323030.5
 DUOXA2
 dual oxidase maturation factor 2
chr6_+_26217159 0.16 ENST00000303910.2
 HIST1H2AE
 histone cluster 1, H2ae
chr3_+_132036207 0.16 ENST00000336375.5
ENST00000495911.1
 ACPP
 acid phosphatase, prostate
chr12_-_95941987 0.15 ENST00000537435.2
 USP44
 ubiquitin specific peptidase 44
chr3_-_129407535 0.15 ENST00000432054.2
 TMCC1
 transmembrane and coiled-coil domain family 1
chr19_+_50169081 0.15 ENST00000246784.3
 BCL2L12
 BCL2-like 12 (proline rich)
chr19_-_40791302 0.15 ENST00000392038.2
ENST00000578123.1
 AKT2
 v-akt murine thymoma viral oncogene homolog 2
chr12_-_48963829 0.15 ENST00000301046.2
ENST00000549817.1
 LALBA
 lactalbumin, alpha-
chr3_-_112565703 0.15 ENST00000488794.1
 CD200R1L
 CD200 receptor 1-like
chr6_+_43139037 0.14 ENST00000265354.4
 SRF
 serum response factor (c-fos serum response element-binding transcription factor)
chr19_+_35849362 0.14 ENST00000327809.4
 FFAR3
 free fatty acid receptor 3
chr17_-_10707410 0.14 ENST00000581851.1
 LINC00675
 long intergenic non-protein coding RNA 675
chr19_+_41305330 0.14 ENST00000593972.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr22_+_23161491 0.14 ENST00000390316.2
 IGLV3-9
 immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr2_-_8464760 0.14 ENST00000430192.1
 LINC00299
 long intergenic non-protein coding RNA 299
chr1_-_154832316 0.13 ENST00000361147.4
 KCNN3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_+_31588478 0.13 ENST00000376007.4
ENST00000376033.2
 PRRC2A
 proline-rich coiled-coil 2A
chr12_+_81110684 0.13 ENST00000228644.3
 MYF5
 myogenic factor 5
chrX_-_84634737 0.13 ENST00000262753.4
 POF1B
 premature ovarian failure, 1B
chr16_+_56691606 0.13 ENST00000334350.6
 MT1F
 metallothionein 1F
chr15_+_67841330 0.13 ENST00000354498.5
 MAP2K5
 mitogen-activated protein kinase kinase 5
chr2_+_114163945 0.13 ENST00000453673.3
 IGKV1OR2-108
 immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr19_-_50169064 0.13 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
 IRF3
 interferon regulatory factor 3
chr5_-_36301984 0.13 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
 RANBP3L
 RAN binding protein 3-like
chr18_-_53253112 0.13 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
 TCF4
 transcription factor 4
chr2_+_220144052 0.12 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr2_-_89247338 0.12 ENST00000496168.1
 IGKV1-5
 immunoglobulin kappa variable 1-5
chr4_+_184826418 0.12 ENST00000308497.4
ENST00000438269.1
 STOX2
 storkhead box 2
chr3_-_24207039 0.12 ENST00000280696.5
 THRB
 thyroid hormone receptor, beta
chr2_+_90273679 0.12 ENST00000423080.2
 IGKV3D-7
 immunoglobulin kappa variable 3D-7
chr6_+_27782788 0.12 ENST00000359465.4
 HIST1H2BM
 histone cluster 1, H2bm
chr6_-_33679452 0.12 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
 UQCC2
 ubiquinol-cytochrome c reductase complex assembly factor 2
chr12_-_56359802 0.12 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
 PMEL
 premelanosome protein
chr19_+_19144384 0.12 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
 ARMC6
 armadillo repeat containing 6
chr4_-_25865159 0.12 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
 SEL1L3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
chr14_-_106866934 0.12 ENST00000390618.2
 IGHV3-38
 immunoglobulin heavy variable 3-38 (non-functional)
chr2_+_220143989 0.12 ENST00000336576.5
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr11_+_112047087 0.12 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
 BCO2
 beta-carotene oxygenase 2
chr19_-_50168962 0.12 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
 IRF3
 interferon regulatory factor 3
chr6_+_148663729 0.12 ENST00000367467.3
 SASH1
 SAM and SH3 domain containing 1
chr12_-_100656134 0.11 ENST00000548313.1
 DEPDC4
 DEP domain containing 4
chr5_-_169626104 0.11 ENST00000520275.1
ENST00000506431.2
 CTB-27N1.1
 CTB-27N1.1
chr2_+_16080659 0.11 ENST00000281043.3
 MYCN
 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr19_+_35861831 0.11 ENST00000454971.1
 GPR42
 G protein-coupled receptor 42 (gene/pseudogene)
chr21_+_17566643 0.11 ENST00000419952.1
ENST00000445461.2
 LINC00478
 long intergenic non-protein coding RNA 478
chr14_-_107199464 0.11 ENST00000433072.2
 IGHV3-72
 immunoglobulin heavy variable 3-72
chr19_+_56111680 0.11 ENST00000301073.3
 ZNF524
 zinc finger protein 524
chr1_+_149858461 0.11 ENST00000331380.2
 HIST2H2AC
 histone cluster 2, H2ac
chr12_-_122238464 0.11 ENST00000546227.1
 RHOF
 ras homolog family member F (in filopodia)
chr19_-_41903161 0.11 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
 EXOSC5
 exosome component 5
chr6_-_26216872 0.10 ENST00000244601.3
 HIST1H2BG
 histone cluster 1, H2bg
chr1_+_61547894 0.10 ENST00000403491.3
 NFIA
 nuclear factor I/A
chr18_+_44526786 0.10 ENST00000245121.5
ENST00000356157.7
 KATNAL2
 katanin p60 subunit A-like 2
chr19_-_44124019 0.10 ENST00000300811.3
 ZNF428
 zinc finger protein 428
chr12_+_19358228 0.10 ENST00000424268.1
ENST00000543806.1
 PLEKHA5
 pleckstrin homology domain containing, family A member 5
chr12_+_43086018 0.10 ENST00000550177.1
 RP11-25I15.3
 RP11-25I15.3
chr12_+_7052974 0.10 ENST00000544681.1
ENST00000537087.1
 C12orf57
 chromosome 12 open reading frame 57
chr3_+_132036243 0.10 ENST00000475741.1
ENST00000351273.7
 ACPP
 acid phosphatase, prostate
chr2_+_90259593 0.10 ENST00000471857.1
 IGKV1D-8
 immunoglobulin kappa variable 1D-8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 2.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.1 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.5 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.6 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.3 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 2.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.5 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.7 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.4 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.2 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.3 GO:0071888 positive regulation of type I interferon-mediated signaling pathway(GO:0060340) macrophage apoptotic process(GO:0071888)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 2.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.0 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 1.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0070863 positive regulation of protein glycosylation(GO:0060050) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 5.9 GO:0000786 nucleosome(GO:0000786)
0.1 0.3 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.5 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 1.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint