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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for PRRX1_ALX4_PHOX2A

Z-value: 1.67

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Transcription factors associated with PRRX1_ALX4_PHOX2A

Gene Symbol Gene ID Gene Info
ENSG00000116132.7 PRRX1
ENSG00000052850.5 ALX4
ENSG00000165462.5 PHOX2A

Activity-expression correlation:

Activity profile of PRRX1_ALX4_PHOX2A motif

Sorted Z-values of PRRX1_ALX4_PHOX2A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRRX1_ALX4_PHOX2A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_69865866 5.05 ENST00000354393.2
MYPN
myopalladin
chr1_-_92371839 4.55 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr12_-_91546926 3.78 ENST00000550758.1
DCN
decorin
chr2_-_145278475 3.57 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr13_+_102142296 3.07 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_-_111093759 2.79 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr1_+_183774240 2.54 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr5_-_111312622 2.22 ENST00000395634.3
NREP
neuronal regeneration related protein
chr1_-_232651312 1.90 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr3_-_195310802 1.89 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr2_+_152214098 1.64 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_-_91573132 1.32 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr12_-_91573316 1.28 ENST00000393155.1
DCN
decorin
chr12_+_59989918 1.20 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_-_145275228 1.19 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chrX_+_77166172 1.15 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr16_+_53133070 1.09 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr11_-_96076334 1.09 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr3_+_69985734 1.06 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr3_-_164914640 0.97 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr5_+_140743859 0.89 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr4_+_160188889 0.88 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_122653630 0.87 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr7_+_90338712 0.85 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr12_-_52946923 0.84 ENST00000267119.5
KRT71
keratin 71
chr20_+_31823792 0.83 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr12_+_18414446 0.83 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr6_-_154751629 0.74 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr10_+_89420706 0.73 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr12_-_91573249 0.68 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr14_+_95078714 0.67 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_47219733 0.62 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr3_+_12329397 0.61 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr19_+_50016610 0.61 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr6_+_34204642 0.58 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr1_-_241799232 0.55 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr17_+_39240459 0.54 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr5_-_160279207 0.53 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr9_-_95244781 0.53 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr5_+_140762268 0.50 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr8_-_93107443 0.46 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_5321549 0.45 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr20_-_34025999 0.45 ENST00000374369.3
GDF5
growth differentiation factor 5
chr4_-_83769996 0.44 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_+_54683419 0.44 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr8_+_38677850 0.43 ENST00000518809.1
ENST00000520611.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr2_-_145277882 0.42 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr1_-_68698222 0.42 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chrX_+_9431324 0.41 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr1_-_68698197 0.40 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr3_+_69985792 0.39 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr8_-_57472154 0.39 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
LINC00968
long intergenic non-protein coding RNA 968
chr2_-_175711133 0.38 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr3_-_186262166 0.38 ENST00000307944.5
CRYGS
crystallin, gamma S
chr6_-_152639479 0.36 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_+_206557366 0.36 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_63439013 0.35 ENST00000398868.3
ATL3
atlastin GTPase 3
chr13_+_53602894 0.35 ENST00000219022.2
OLFM4
olfactomedin 4
chr10_+_90672113 0.34 ENST00000371922.1
STAMBPL1
STAM binding protein-like 1
chr8_-_93107696 0.34 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_26724784 0.33 ENST00000380573.3
ADRA1A
adrenoceptor alpha 1A
chr7_+_90339169 0.32 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr15_+_51669444 0.32 ENST00000396399.2
GLDN
gliomedin
chr15_-_52970820 0.29 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr17_+_44588877 0.28 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr12_-_118796910 0.27 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr7_-_27169801 0.27 ENST00000511914.1
HOXA4
homeobox A4
chr2_+_101437487 0.27 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr12_-_107380846 0.26 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3
MTERF domain containing 3
chr2_+_228678550 0.25 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr10_-_31146615 0.25 ENST00000444692.2
ZNF438
zinc finger protein 438
chr20_-_18477862 0.24 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chr7_+_148287657 0.24 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr12_-_92539614 0.24 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr3_+_138340049 0.24 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr5_+_137203465 0.24 ENST00000239926.4
MYOT
myotilin
chr6_-_107235331 0.24 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr12_-_107380910 0.24 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr5_+_140079919 0.23 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr8_+_77318769 0.23 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr17_-_56082455 0.23 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr1_+_114471809 0.22 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr15_-_37393406 0.22 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr3_-_124774802 0.22 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr2_-_161350305 0.22 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr7_+_55980331 0.22 ENST00000429591.2
ZNF713
zinc finger protein 713
chr5_-_142780280 0.22 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr11_+_12766583 0.22 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_+_165878100 0.21 ENST00000513876.2
FAM218A
family with sequence similarity 218, member A
chr4_-_119759795 0.21 ENST00000419654.2
SEC24D
SEC24 family member D
chr17_-_39623681 0.21 ENST00000225899.3
KRT32
keratin 32
chr3_+_138340067 0.21 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr5_+_140571902 0.21 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr12_+_75784850 0.21 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr6_+_153552455 0.20 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr3_+_159943362 0.20 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr1_+_12916941 0.20 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr4_+_113568207 0.20 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr11_-_82708435 0.20 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr10_-_29923893 0.20 ENST00000355867.4
SVIL
supervillin
chr3_-_12587055 0.20 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr5_+_140514782 0.20 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr1_+_84630645 0.20 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr15_+_66874502 0.19 ENST00000558797.1
RP11-321F6.1
HCG2003567; Uncharacterized protein
chr3_-_157824292 0.19 ENST00000483851.2
SHOX2
short stature homeobox 2
chr19_+_13842559 0.19 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr8_-_57123815 0.18 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr4_+_76649797 0.18 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr19_-_44388116 0.18 ENST00000587539.1
ZNF404
zinc finger protein 404
chr1_+_52682052 0.18 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr5_+_98109322 0.18 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr7_-_140482926 0.18 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr12_-_53601055 0.18 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr4_+_142558078 0.18 ENST00000529613.1
IL15
interleukin 15
chr1_+_44679159 0.17 ENST00000315913.5
ENST00000372289.2
DMAP1
DNA methyltransferase 1 associated protein 1
chr3_+_111393501 0.17 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr13_-_81801115 0.17 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr5_+_59783540 0.17 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr12_+_120105558 0.17 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr12_-_53601000 0.16 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr11_+_66276550 0.16 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr14_+_52164820 0.16 ENST00000554167.1
FRMD6
FERM domain containing 6
chr10_+_13142225 0.16 ENST00000378747.3
OPTN
optineurin
chr17_-_14683517 0.16 ENST00000379640.1
AC005863.1
AC005863.1
chr17_-_71228357 0.16 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr17_+_74463650 0.16 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr6_+_116691001 0.16 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr5_-_66492562 0.15 ENST00000256447.4
CD180
CD180 molecule
chrX_-_15332665 0.15 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr15_+_44719970 0.15 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr14_+_88851874 0.15 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr3_-_149293990 0.15 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr14_-_75536182 0.15 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr7_+_138145076 0.15 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr3_+_40518599 0.14 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr16_+_1728257 0.14 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr3_-_18480260 0.14 ENST00000454909.2
SATB1
SATB homeobox 1
chr5_+_68860949 0.14 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr5_-_70272055 0.14 ENST00000514857.2
NAIP
NLR family, apoptosis inhibitory protein
chr10_-_90967063 0.14 ENST00000371852.2
CH25H
cholesterol 25-hydroxylase
chr12_-_81992111 0.14 ENST00000443686.3
ENST00000407050.4
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_+_57671888 0.14 ENST00000391612.1
AL391152.1
AL391152.1
chr10_+_35464513 0.14 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
CREM
cAMP responsive element modulator
chr4_-_23735183 0.13 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr1_+_114471972 0.13 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr14_+_21467414 0.13 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr19_-_11456905 0.13 ENST00000588560.1
ENST00000592952.1
TMEM205
transmembrane protein 205
chr5_+_133562095 0.13 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr8_+_11961898 0.13 ENST00000400085.3
ZNF705D
zinc finger protein 705D
chr17_-_46690839 0.13 ENST00000498634.2
HOXB8
homeobox B8
chr9_-_95298314 0.13 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr5_-_54468974 0.13 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr7_+_23338819 0.13 ENST00000466681.1
MALSU1
mitochondrial assembly of ribosomal large subunit 1
chr8_-_62602327 0.13 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr19_-_11456722 0.12 ENST00000354882.5
TMEM205
transmembrane protein 205
chr15_-_75748115 0.12 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr9_+_2159850 0.12 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_31895254 0.12 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr1_+_158978768 0.12 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr12_-_10151773 0.12 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr10_+_134150835 0.12 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr15_+_75628394 0.12 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr15_+_57511609 0.12 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr22_+_25615489 0.12 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr17_+_71228793 0.12 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr1_-_165414414 0.11 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr4_-_83765613 0.11 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr15_-_26874230 0.11 ENST00000400188.3
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr15_+_75628232 0.11 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr2_-_58468437 0.11 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr6_+_132891461 0.11 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr9_+_34652164 0.11 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chrX_-_48858630 0.11 ENST00000376425.3
ENST00000376444.3
GRIPAP1
GRIP1 associated protein 1
chrX_-_48858667 0.11 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr2_-_172087824 0.11 ENST00000521943.1
TLK1
tousled-like kinase 1
chr17_+_71228537 0.11 ENST00000577615.1
ENST00000585109.1
C17orf80
chromosome 17 open reading frame 80
chr9_-_123639600 0.11 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_+_154401791 0.11 ENST00000476006.1
IL6R
interleukin 6 receptor
chr10_+_18689637 0.10 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chrX_+_16668278 0.10 ENST00000380200.3
S100G
S100 calcium binding protein G
chr15_-_65407524 0.10 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr5_+_169780485 0.10 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr14_-_81425828 0.10 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr12_-_25150409 0.10 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr1_+_44679113 0.10 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1
DNA methyltransferase 1 associated protein 1
chr8_+_7353368 0.10 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr19_-_51920835 0.10 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr19_-_11456872 0.10 ENST00000586218.1
TMEM205
transmembrane protein 205
chr12_+_12878829 0.10 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr5_-_16738451 0.10 ENST00000274203.9
ENST00000515803.1
MYO10
myosin X
chr11_-_111649015 0.10 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr10_+_13141585 0.09 ENST00000378764.2
OPTN
optineurin
chr19_+_36630454 0.09 ENST00000246533.3
CAPNS1
calpain, small subunit 1
chr12_-_43833515 0.09 ENST00000549670.1
ENST00000395541.2
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr21_+_48055527 0.09 ENST00000397638.2
ENST00000458387.2
ENST00000451211.2
ENST00000291705.6
ENST00000397637.1
ENST00000334494.4
ENST00000397628.1
ENST00000440086.1
PRMT2
protein arginine methyltransferase 2
chr9_-_21305312 0.09 ENST00000259555.4
IFNA5
interferon, alpha 5
chrX_+_35937843 0.09 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr12_-_10978957 0.09 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chrX_-_19817869 0.09 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr1_+_115572415 0.09 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699)
0.9 5.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.6 1.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 6.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4 1.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.3 0.9 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 0.9 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 5.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.8 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.2 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 1.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.3 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.9 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.9 GO:0030728 ovulation(GO:0030728)
0.0 1.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.8 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.5 7.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.0 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 5.2 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 4.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 1.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.3 1.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 0.7 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 5.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.1 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 5.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 6.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.5 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 1.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0097027 anaphase-promoting complex binding(GO:0010997) ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 5.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane