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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RAD21_SMC3

Z-value: 0.39

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Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
RAD21
ENSG00000164754.8 RAD21
SMC3
ENSG00000108055.9 SMC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMC3hg19_v2_chr10_+_112327425_1123275160.621.0e-01Click!
RAD21hg19_v2_chr8_-_117886955_1178871050.049.3e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_114737472 2.19 ENST00000420161.1
 AC110769.3
 AC110769.3
chr2_+_114737146 1.28 ENST00000412690.1
 AC010982.1
 AC010982.1
chr7_+_89783689 1.15 ENST00000297205.2
 STEAP1
 six transmembrane epithelial antigen of the prostate 1
chr13_+_31774073 1.05 ENST00000343307.4
 B3GALTL
 beta 1,3-galactosyltransferase-like
chr6_+_138188551 0.86 ENST00000237289.4
ENST00000433680.1
 TNFAIP3
 tumor necrosis factor, alpha-induced protein 3
chr15_+_45722727 0.86 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
 C15orf48
 chromosome 15 open reading frame 48
chr5_-_139726181 0.85 ENST00000507104.1
ENST00000230990.6
 HBEGF
 heparin-binding EGF-like growth factor
chr8_+_28480246 0.81 ENST00000523149.1
 EXTL3
 exostosin-like glycosyltransferase 3
chr10_-_15413035 0.81 ENST00000378116.4
ENST00000455654.1
 FAM171A1
 family with sequence similarity 171, member A1
chr19_-_36001113 0.81 ENST00000434389.1
 DMKN
 dermokine
chr1_+_186344945 0.80 ENST00000419367.3
ENST00000287859.6
 C1orf27
 chromosome 1 open reading frame 27
chr1_+_212208919 0.76 ENST00000366991.4
ENST00000542077.1
 DTL
 denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr10_-_76995675 0.74 ENST00000469299.1
 COMTD1
 catechol-O-methyltransferase domain containing 1
chr19_-_36001286 0.73 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
 DMKN
 dermokine
chr1_-_186344456 0.73 ENST00000367478.4
 TPR
 translocated promoter region, nuclear basket protein
chr5_+_140254884 0.71 ENST00000398631.2
 PCDHA12
 protocadherin alpha 12
chr10_-_76995769 0.71 ENST00000372538.3
 COMTD1
 catechol-O-methyltransferase domain containing 1
chr15_-_34502197 0.71 ENST00000557877.1
 KATNBL1
 katanin p80 subunit B-like 1
chr1_-_186344802 0.68 ENST00000451586.1
 TPR
 translocated promoter region, nuclear basket protein
chr1_+_186344883 0.65 ENST00000367470.3
 C1orf27
 chromosome 1 open reading frame 27
chr18_-_47721447 0.63 ENST00000285039.7
 MYO5B
 myosin VB
chr7_-_22539771 0.61 ENST00000406890.2
ENST00000424363.1
 STEAP1B
 STEAP family member 1B
chr1_-_159915386 0.58 ENST00000361509.3
ENST00000368094.1
 IGSF9
 immunoglobulin superfamily, member 9
chr3_-_190040223 0.58 ENST00000295522.3
 CLDN1
 claudin 1
chr1_+_92495528 0.55 ENST00000370383.4
 EPHX4
 epoxide hydrolase 4
chr6_-_44225231 0.54 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
 SLC35B2
 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr19_+_58341656 0.53 ENST00000442832.4
ENST00000594901.1
 ZNF587B
 zinc finger protein 587B
chr22_-_50050986 0.51 ENST00000405854.1
 C22orf34
 chromosome 22 open reading frame 34
chr7_-_16840820 0.51 ENST00000450569.1
 AGR2
 anterior gradient 2
chr11_+_60691924 0.49 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
 TMEM132A
 transmembrane protein 132A
chr15_-_34659349 0.49 ENST00000314891.6
 LPCAT4
 lysophosphatidylcholine acyltransferase 4
chr11_+_20409070 0.49 ENST00000331079.6
 PRMT3
 protein arginine methyltransferase 3
chr1_-_94374946 0.49 ENST00000370238.3
 GCLM
 glutamate-cysteine ligase, modifier subunit
chr10_-_79789291 0.47 ENST00000372371.3
 POLR3A
 polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr12_-_120763739 0.46 ENST00000549767.1
 PLA2G1B
 phospholipase A2, group IB (pancreas)
chr4_+_56815102 0.46 ENST00000257287.4
 CEP135
 centrosomal protein 135kDa
chr18_-_21166841 0.45 ENST00000269228.5
 NPC1
 Niemann-Pick disease, type C1
chr9_+_116917807 0.45 ENST00000356083.3
 COL27A1
 collagen, type XXVII, alpha 1
chr8_+_67341239 0.44 ENST00000320270.2
 RRS1
 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr10_+_81107216 0.43 ENST00000394579.3
ENST00000225174.3
 PPIF
 peptidylprolyl isomerase F
chr17_-_34890732 0.42 ENST00000268852.9
 MYO19
 myosin XIX
chr8_+_24772455 0.40 ENST00000433454.2
 NEFM
 neurofilament, medium polypeptide
chr19_+_4791722 0.40 ENST00000269856.3
 FEM1A
 fem-1 homolog a (C. elegans)
chr20_-_4721314 0.39 ENST00000418528.1
ENST00000326539.2
ENST00000423718.2
 PRNT
 prion protein (testis specific)
chr8_-_145550571 0.39 ENST00000332324.4
 DGAT1
 diacylglycerol O-acyltransferase 1
chr11_+_64216546 0.39 ENST00000316124.2
 AP003774.4
 HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
chrX_-_117119243 0.39 ENST00000539496.1
ENST00000469946.1
 KLHL13
 kelch-like family member 13
chr3_+_172468472 0.39 ENST00000232458.5
ENST00000392692.3
 ECT2
 epithelial cell transforming sequence 2 oncogene
chr11_-_11643540 0.39 ENST00000227756.4
 GALNT18
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
chr12_+_50898881 0.38 ENST00000301180.5
 DIP2B
 DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr22_+_22735135 0.38 ENST00000390297.2
 IGLV1-44
 immunoglobulin lambda variable 1-44
chr19_-_1876156 0.38 ENST00000565797.1
 CTB-31O20.2
 CTB-31O20.2
chr17_-_61523622 0.38 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
 CYB561
 cytochrome b561
chr3_+_50192499 0.37 ENST00000413852.1
 SEMA3F
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr15_+_75074385 0.37 ENST00000220003.9
 CSK
 c-src tyrosine kinase
chr13_-_37573432 0.37 ENST00000413537.2
ENST00000443765.1
ENST00000239891.3
 ALG5
 ALG5, dolichyl-phosphate beta-glucosyltransferase
chr4_-_41884620 0.37 ENST00000504870.1
 LINC00682
 long intergenic non-protein coding RNA 682
chr3_+_172468505 0.36 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
 ECT2
 epithelial cell transforming sequence 2 oncogene
chr1_-_40367530 0.36 ENST00000372816.2
ENST00000372815.1
 MYCL
 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr17_-_34890759 0.36 ENST00000431794.3
 MYO19
 myosin XIX
chr10_-_103603523 0.35 ENST00000370046.1
 KCNIP2
 Kv channel interacting protein 2
chr16_-_88851618 0.35 ENST00000301015.9
 PIEZO1
 piezo-type mechanosensitive ion channel component 1
chr5_+_175875349 0.35 ENST00000261942.6
 FAF2
 Fas associated factor family member 2
chr1_+_15480197 0.35 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
 TMEM51
 transmembrane protein 51
chr5_+_145826867 0.35 ENST00000296702.5
ENST00000394421.2
 TCERG1
 transcription elongation regulator 1
chr2_+_69240415 0.34 ENST00000409829.3
 ANTXR1
 anthrax toxin receptor 1
chr11_-_104480019 0.34 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
 RP11-886D15.1
 RP11-886D15.1
chr6_-_32806506 0.34 ENST00000374897.2
ENST00000452392.2
 TAP2
TAP2
 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr12_+_13197218 0.33 ENST00000197268.8
 KIAA1467
 KIAA1467
chr17_+_7621045 0.33 ENST00000570791.1
 DNAH2
 dynein, axonemal, heavy chain 2
chr19_-_58400148 0.33 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
 ZNF814
 zinc finger protein 814
chr5_+_140165876 0.33 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
 PCDHA1
 protocadherin alpha 1
chr8_+_101170563 0.32 ENST00000520508.1
ENST00000388798.2
 SPAG1
 sperm associated antigen 1
chr6_+_151186554 0.32 ENST00000367321.3
ENST00000367307.4
 MTHFD1L
 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr11_-_113644491 0.32 ENST00000200135.3
 ZW10
 zw10 kinetochore protein
chr16_-_66864806 0.32 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
 NAE1
 NEDD8 activating enzyme E1 subunit 1
chr7_+_156742399 0.31 ENST00000275820.3
 NOM1
 nucleolar protein with MIF4G domain 1
chr7_+_150521691 0.31 ENST00000493429.1
 AOC1
 amine oxidase, copper containing 1
chr17_+_38137073 0.31 ENST00000541736.1
 PSMD3
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr5_+_140201183 0.31 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
 PCDHA5
 protocadherin alpha 5
chr12_+_110338063 0.30 ENST00000405876.4
 TCHP
 trichoplein, keratin filament binding
chrX_+_49969405 0.30 ENST00000376042.1
 CCNB3
 cyclin B3
chr3_-_196756646 0.30 ENST00000439320.1
ENST00000296351.4
ENST00000296350.5
 MFI2
 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr8_-_145669791 0.30 ENST00000409379.3
 TONSL
 tonsoku-like, DNA repair protein
chr2_+_11273179 0.30 ENST00000381585.3
ENST00000405022.3
 C2orf50
 chromosome 2 open reading frame 50
chr20_+_55205825 0.30 ENST00000544508.1
 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr2_+_220492287 0.29 ENST00000273063.6
ENST00000373762.3
 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
chr10_+_13203543 0.29 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
 MCM10
 minichromosome maintenance complex component 10
chr6_-_11044509 0.29 ENST00000354666.3
 ELOVL2
 ELOVL fatty acid elongase 2
chr4_+_56814968 0.29 ENST00000422247.2
 CEP135
 centrosomal protein 135kDa
chr19_-_49496557 0.29 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
 GYS1
 glycogen synthase 1 (muscle)
chr14_-_54908043 0.28 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
 CNIH1
 cornichon family AMPA receptor auxiliary protein 1
chr13_+_33160553 0.28 ENST00000315596.10
 PDS5B
 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr15_+_92396920 0.28 ENST00000318445.6
 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
chr18_+_60382672 0.28 ENST00000400316.4
ENST00000262719.5
 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
chr1_+_18081804 0.28 ENST00000375406.1
 ACTL8
 actin-like 8
chr12_-_102224704 0.28 ENST00000299314.7
 GNPTAB
 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr8_+_101170257 0.28 ENST00000251809.3
 SPAG1
 sperm associated antigen 1
chr17_-_27507395 0.28 ENST00000354329.4
ENST00000527372.1
 MYO18A
 myosin XVIIIA
chr10_-_6019984 0.28 ENST00000525219.2
 IL15RA
 interleukin 15 receptor, alpha
chr22_+_22901750 0.28 ENST00000407120.1
 LL22NC03-63E9.3
 Uncharacterized protein
chr10_-_96122682 0.28 ENST00000371361.3
 NOC3L
 nucleolar complex associated 3 homolog (S. cerevisiae)
chr10_-_101769617 0.27 ENST00000324109.4
ENST00000342239.3
 DNMBP
 dynamin binding protein
chr2_+_220492373 0.27 ENST00000317151.3
 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
chr11_-_119599794 0.27 ENST00000264025.3
 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr16_+_22308717 0.27 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
 POLR3E
 polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr16_-_23568651 0.27 ENST00000563232.1
ENST00000563459.1
ENST00000449606.1
 EARS2
 glutamyl-tRNA synthetase 2, mitochondrial
chr17_-_72919317 0.27 ENST00000319642.1
 USH1G
 Usher syndrome 1G (autosomal recessive)
chr17_-_27507377 0.26 ENST00000531253.1
 MYO18A
 myosin XVIIIA
chr14_+_22356029 0.26 ENST00000390437.2
 TRAV12-2
 T cell receptor alpha variable 12-2
chr1_+_151129103 0.26 ENST00000368910.3
 TNFAIP8L2
 tumor necrosis factor, alpha-induced protein 8-like 2
chr12_+_110338323 0.26 ENST00000312777.5
ENST00000536408.2
 TCHP
 trichoplein, keratin filament binding
chr21_-_36262032 0.26 ENST00000325074.5
ENST00000399237.2
 RUNX1
 runt-related transcription factor 1
chr6_-_139308777 0.26 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
 REPS1
 RALBP1 associated Eps domain containing 1
chr14_+_22217447 0.26 ENST00000390427.3
 TRAV5
 T cell receptor alpha variable 5
chr6_+_155054459 0.26 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
 SCAF8
 SR-related CTD-associated factor 8
chr22_-_43583079 0.26 ENST00000216129.6
 TTLL12
 tubulin tyrosine ligase-like family, member 12
chr11_+_85566422 0.25 ENST00000342404.3
 CCDC83
 coiled-coil domain containing 83
chr12_-_51663959 0.25 ENST00000604188.1
ENST00000398453.3
 SMAGP
 small cell adhesion glycoprotein
chr9_-_35096545 0.25 ENST00000378617.3
ENST00000341666.3
ENST00000361778.2
 PIGO
 phosphatidylinositol glycan anchor biosynthesis, class O
chr1_-_6614565 0.25 ENST00000377705.5
 NOL9
 nucleolar protein 9
chr8_+_42948641 0.25 ENST00000518991.1
ENST00000331373.5
 POMK
 protein-O-mannose kinase
chr22_-_50051151 0.25 ENST00000400023.1
ENST00000444628.1
 C22orf34
 chromosome 22 open reading frame 34
chr5_+_137688285 0.24 ENST00000314358.5
 KDM3B
 lysine (K)-specific demethylase 3B
chr15_-_44487408 0.24 ENST00000402883.1
ENST00000417257.1
 FRMD5
 FERM domain containing 5
chr16_+_16326352 0.24 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
 NOMO3
 NODAL modulator 3
chr12_-_121410095 0.24 ENST00000539163.1
 AC079602.1
 AC079602.1
chr5_+_150827143 0.24 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
 SLC36A1
 solute carrier family 36 (proton/amino acid symporter), member 1
chr4_-_41884582 0.24 ENST00000499082.2
 LINC00682
 long intergenic non-protein coding RNA 682
chr11_+_7110165 0.24 ENST00000306904.5
 RBMXL2
 RNA binding motif protein, X-linked-like 2
chr12_-_51663728 0.24 ENST00000603864.1
ENST00000605426.1
 SMAGP
 small cell adhesion glycoprotein
chr5_-_140998616 0.24 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
 DIAPH1
 diaphanous-related formin 1
chr17_+_17584763 0.24 ENST00000353383.1
 RAI1
 retinoic acid induced 1
chr19_-_36004543 0.24 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
 DMKN
 dermokine
chr11_+_66025938 0.24 ENST00000394066.2
 KLC2
 kinesin light chain 2
chr17_+_65713925 0.24 ENST00000253247.4
 NOL11
 nucleolar protein 11
chr12_-_95510743 0.23 ENST00000551521.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr19_+_10123925 0.23 ENST00000591589.1
ENST00000171214.1
 RDH8
 retinol dehydrogenase 8 (all-trans)
chr2_+_90108504 0.23 ENST00000390271.2
 IGKV6D-41
 immunoglobulin kappa variable 6D-41 (non-functional)
chr16_-_18573396 0.23 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
 NOMO2
 NODAL modulator 2
chr6_-_139309378 0.23 ENST00000450536.2
ENST00000258062.5
 REPS1
 RALBP1 associated Eps domain containing 1
chr5_+_140220769 0.23 ENST00000531613.1
ENST00000378123.3
 PCDHA8
 protocadherin alpha 8
chr22_+_22764088 0.23 ENST00000390299.2
 IGLV1-40
 immunoglobulin lambda variable 1-40
chr8_+_22446763 0.23 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
 AC037459.4
 Uncharacterized protein
chr20_+_30102231 0.23 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
 HM13
 histocompatibility (minor) 13
chr17_-_35716019 0.22 ENST00000591148.1
ENST00000394406.2
ENST00000394403.1
 ACACA
 acetyl-CoA carboxylase alpha
chr7_-_91509986 0.22 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
 MTERF
 mitochondrial transcription termination factor
chr7_+_112120908 0.22 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
 LSMEM1
 leucine-rich single-pass membrane protein 1
chr17_+_7591747 0.22 ENST00000534050.1
 WRAP53
 WD repeat containing, antisense to TP53
chr1_-_156390128 0.22 ENST00000368242.3
 C1orf61
 chromosome 1 open reading frame 61
chr2_+_102972363 0.22 ENST00000409599.1
 IL18R1
 interleukin 18 receptor 1
chr17_+_65714018 0.22 ENST00000581106.1
ENST00000535137.1
 NOL11
 nucleolar protein 11
chr17_+_38137050 0.22 ENST00000264639.4
 PSMD3
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr17_+_7591639 0.21 ENST00000396463.2
 WRAP53
 WD repeat containing, antisense to TP53
chr16_+_1756162 0.21 ENST00000250894.4
ENST00000356010.5
 MAPK8IP3
 mitogen-activated protein kinase 8 interacting protein 3
chr11_+_118826999 0.21 ENST00000264031.2
 UPK2
 uroplakin 2
chr16_+_71392616 0.21 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
 CALB2
 calbindin 2
chr11_+_46368975 0.21 ENST00000527911.1
 DGKZ
 diacylglycerol kinase, zeta
chr3_+_141594966 0.21 ENST00000475483.1
 ATP1B3
 ATPase, Na+/K+ transporting, beta 3 polypeptide
chr14_+_23305760 0.21 ENST00000311852.6
 MMP14
 matrix metallopeptidase 14 (membrane-inserted)
chr2_+_69240511 0.21 ENST00000409349.3
 ANTXR1
 anthrax toxin receptor 1
chr10_+_104154229 0.21 ENST00000428099.1
ENST00000369966.3
 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_-_117103208 0.20 ENST00000320934.3
ENST00000530269.1
 PCSK7
 proprotein convertase subtilisin/kexin type 7
chr4_-_128887069 0.20 ENST00000541133.1
ENST00000296468.3
ENST00000513559.1
 MFSD8
 major facilitator superfamily domain containing 8
chr10_+_103892787 0.20 ENST00000278070.2
ENST00000413464.2
 PPRC1
 peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr5_-_140998481 0.20 ENST00000518047.1
 DIAPH1
 diaphanous-related formin 1
chr1_-_6761855 0.20 ENST00000426784.1
ENST00000377573.5
ENST00000377577.5
ENST00000294401.7
 DNAJC11
 DnaJ (Hsp40) homolog, subfamily C, member 11
chr20_+_43992094 0.20 ENST00000453003.1
 SYS1
 SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr14_+_22771851 0.20 ENST00000390466.1
 TRAV39
 T cell receptor alpha variable 39
chr6_-_136871957 0.20 ENST00000354570.3
 MAP7
 microtubule-associated protein 7
chr11_+_46369077 0.20 ENST00000456247.2
ENST00000421244.2
ENST00000318201.8
 DGKZ
 diacylglycerol kinase, zeta
chr17_+_41561317 0.20 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
 DHX8
 DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr18_+_43753974 0.19 ENST00000282059.6
ENST00000321319.6
 C18orf25
 chromosome 18 open reading frame 25
chr3_-_183735731 0.19 ENST00000334444.6
 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_-_128369643 0.19 ENST00000296255.3
 RPN1
 ribophorin I
chr3_-_64009658 0.19 ENST00000394431.2
 PSMD6
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr10_-_6622258 0.19 ENST00000263125.5
 PRKCQ
 protein kinase C, theta
chr12_+_49372251 0.19 ENST00000293549.3
 WNT1
 wingless-type MMTV integration site family, member 1
chr5_-_141257954 0.19 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
 PCDH1
 protocadherin 1
chr3_+_140950612 0.19 ENST00000286353.4
ENST00000502783.1
ENST00000393010.2
ENST00000514680.1
 ACPL2
 acid phosphatase-like 2
chr10_-_6622201 0.19 ENST00000539722.1
ENST00000397176.2
 PRKCQ
 protein kinase C, theta
chr1_+_29063119 0.19 ENST00000474884.1
ENST00000542507.1
 YTHDF2
 YTH domain family, member 2
chr11_+_46368956 0.19 ENST00000543978.1
 DGKZ
 diacylglycerol kinase, zeta
chr1_-_211307404 0.18 ENST00000367007.4
 KCNH1
 potassium voltage-gated channel, subfamily H (eag-related), member 1
chr3_-_50340996 0.18 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
 HYAL1
 hyaluronoglucosaminidase 1
chr6_+_35310391 0.18 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
 PPARD
 peroxisome proliferator-activated receptor delta
chr16_-_49315731 0.18 ENST00000219197.6
 CBLN1
 cerebellin 1 precursor
chrX_+_47053208 0.18 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
 UBA1
 ubiquitin-like modifier activating enzyme 1
chr9_+_138594018 0.18 ENST00000487664.1
ENST00000298480.5
ENST00000371757.2
 KCNT1
 potassium channel, subfamily T, member 1
chr14_+_22309368 0.18 ENST00000390433.1
 TRAV12-1
 T cell receptor alpha variable 12-1
chr12_-_102224457 0.18 ENST00000549165.1
ENST00000549940.1
ENST00000392919.4
 GNPTAB
 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr6_+_25279651 0.18 ENST00000329474.6
 LRRC16A
 leucine rich repeat containing 16A
chr11_+_73675873 0.18 ENST00000537753.1
ENST00000542350.1
 DNAJB13
 DnaJ (Hsp40) homolog, subfamily B, member 13
chr1_-_211307315 0.18 ENST00000271751.4
 KCNH1
 potassium voltage-gated channel, subfamily H (eag-related), member 1
chr19_+_47852538 0.18 ENST00000328771.4
 DHX34
 DEAH (Asp-Glu-Ala-His) box polypeptide 34
chrX_-_103268259 0.17 ENST00000217926.5
 H2BFWT
 H2B histone family, member W, testis-specific
chr4_+_7194247 0.17 ENST00000507866.2
 SORCS2
 sortilin-related VPS10 domain containing receptor 2
chr17_-_33469299 0.17 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
 NLE1
 notchless homolog 1 (Drosophila)
chr11_-_130786400 0.17 ENST00000265909.4
 SNX19
 sorting nexin 19
chr4_-_171011323 0.17 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
 AADAT
 aminoadipate aminotransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 0.6 GO:0071284 cellular response to lead ion(GO:0071284)
0.3 0.9 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.2 0.9 GO:0051541 elastin metabolic process(GO:0051541)
0.2 0.7 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 1.8 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.5 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2 0.5 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.2 0.5 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.4 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.4 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.6 GO:0032439 endosome localization(GO:0032439)
0.1 0.3 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.5 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.5 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.5 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.5 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.2 GO:0061054 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.4 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.2 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.3 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 1.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.3 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.2 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.5 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:1904760 peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.3 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:1901165 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0070671 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.8 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 2.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 0.5 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 1.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.5 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.5 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.3 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.3 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.4 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis