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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for REL

Z-value: 0.94

Motif logo

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
REL
ENSG00000162924.9 REL

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108650_611086870.979.9e-05Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_21529811 1.66 ENST00000588004.1
 LAMA3
 laminin, alpha 3
chr18_+_21452964 1.64 ENST00000587184.1
 LAMA3
 laminin, alpha 3
chr18_+_21452804 1.47 ENST00000269217.6
 LAMA3
 laminin, alpha 3
chr6_+_138188551 1.22 ENST00000237289.4
ENST00000433680.1
 TNFAIP3
 tumor necrosis factor, alpha-induced protein 3
chr2_-_113594279 0.83 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B
 interleukin 1, beta
chr10_-_100027943 0.79 ENST00000260702.3
 LOXL4
 lysyl oxidase-like 4
chr18_+_33877654 0.75 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
 FHOD3
 formin homology 2 domain containing 3
chr20_+_43803517 0.61 ENST00000243924.3
 PI3
 peptidase inhibitor 3, skin-derived
chr1_-_209824643 0.60 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr4_+_74735102 0.60 ENST00000395761.3
 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_+_69064300 0.58 ENST00000342771.4
 AUTS2
 autism susceptibility candidate 2
chr17_-_56492989 0.56 ENST00000583753.1
 RNF43
 ring finger protein 43
chr11_+_10476851 0.54 ENST00000396553.2
 AMPD3
 adenosine monophosphate deaminase 3
chr11_-_58345569 0.50 ENST00000528954.1
ENST00000528489.1
 LPXN
 leupaxin
chr6_+_30850697 0.48 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr12_-_95009837 0.48 ENST00000551457.1
 TMCC3
 transmembrane and coiled-coil domain family 3
chr6_-_143832820 0.48 ENST00000002165.6
 FUCA2
 fucosidase, alpha-L- 2, plasma
chr2_+_163175394 0.43 ENST00000446271.1
ENST00000429691.2
 GCA
 grancalcin, EF-hand calcium binding protein
chr1_+_95582881 0.42 ENST00000370203.4
ENST00000456991.1
 TMEM56
 transmembrane protein 56
chr12_-_86230315 0.38 ENST00000361228.3
 RASSF9
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr12_+_51632666 0.37 ENST00000604900.1
 DAZAP2
 DAZ associated protein 2
chr19_-_51471381 0.37 ENST00000594641.1
 KLK6
 kallikrein-related peptidase 6
chr19_-_51471362 0.36 ENST00000376853.4
ENST00000424910.2
 KLK6
 kallikrein-related peptidase 6
chr19_-_51472031 0.35 ENST00000391808.1
 KLK6
 kallikrein-related peptidase 6
chr17_-_4643114 0.32 ENST00000293778.6
 CXCL16
 chemokine (C-X-C motif) ligand 16
chr2_+_220094479 0.32 ENST00000323348.5
ENST00000453432.1
ENST00000409849.1
ENST00000416565.1
ENST00000410034.3
ENST00000447157.1
 ANKZF1
 ankyrin repeat and zinc finger domain containing 1
chr11_+_102188224 0.32 ENST00000263464.3
 BIRC3
 baculoviral IAP repeat containing 3
chr9_-_117880477 0.31 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
 TNC
 tenascin C
chr9_+_130911770 0.31 ENST00000372998.1
 LCN2
 lipocalin 2
chr1_-_204380919 0.30 ENST00000367188.4
 PPP1R15B
 protein phosphatase 1, regulatory subunit 15B
chr14_+_23842018 0.29 ENST00000397242.2
ENST00000329715.2
 IL25
 interleukin 25
chr11_-_72492878 0.29 ENST00000535054.1
ENST00000545082.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr16_-_88717482 0.29 ENST00000261623.3
 CYBA
 cytochrome b-245, alpha polypeptide
chr19_-_4338838 0.28 ENST00000594605.1
 STAP2
 signal transducing adaptor family member 2
chr8_+_123793633 0.28 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr12_-_122985067 0.28 ENST00000540586.1
ENST00000543897.1
 ZCCHC8
 zinc finger, CCHC domain containing 8
chr19_-_4338783 0.28 ENST00000601482.1
ENST00000600324.1
 STAP2
 signal transducing adaptor family member 2
chr12_-_55375622 0.28 ENST00000316577.8
 TESPA1
 thymocyte expressed, positive selection associated 1
chr8_-_105601134 0.28 ENST00000276654.5
ENST00000424843.2
 LRP12
 low density lipoprotein receptor-related protein 12
chr16_+_27325202 0.27 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
 IL4R
 interleukin 4 receptor
chr10_-_96122682 0.26 ENST00000371361.3
 NOC3L
 nucleolar complex associated 3 homolog (S. cerevisiae)
chr9_-_136004782 0.26 ENST00000393157.3
 RALGDS
 ral guanine nucleotide dissociation stimulator
chr10_+_104155450 0.25 ENST00000471698.1
ENST00000189444.6
 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_+_130911723 0.25 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
 LCN2
 lipocalin 2
chr11_-_72492903 0.25 ENST00000537947.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr16_+_3014217 0.25 ENST00000572045.1
 KREMEN2
 kringle containing transmembrane protein 2
chr3_+_183967409 0.25 ENST00000324557.4
ENST00000402825.3
 ECE2
 endothelin converting enzyme 2
chr2_-_74669009 0.25 ENST00000272430.5
 RTKN
 rhotekin
chr2_-_163175133 0.24 ENST00000421365.2
ENST00000263642.2
 IFIH1
 interferon induced with helicase C domain 1
chr11_+_102188272 0.23 ENST00000532808.1
 BIRC3
 baculoviral IAP repeat containing 3
chr6_+_15401075 0.23 ENST00000541660.1
 JARID2
 jumonji, AT rich interactive domain 2
chr6_+_32121908 0.23 ENST00000375143.2
ENST00000424499.1
 PPT2
 palmitoyl-protein thioesterase 2
chr6_-_44233361 0.23 ENST00000275015.5
 NFKBIE
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr6_+_32121789 0.22 ENST00000437001.2
ENST00000375137.2
 PPT2
 palmitoyl-protein thioesterase 2
chr2_+_61108650 0.22 ENST00000295025.8
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr7_+_128784712 0.22 ENST00000289407.4
 TSPAN33
 tetraspanin 33
chr14_+_103243813 0.22 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
 TRAF3
 TNF receptor-associated factor 3
chr14_+_68086515 0.22 ENST00000261783.3
 ARG2
 arginase 2
chr7_-_16844611 0.21 ENST00000401412.1
ENST00000419304.2
 AGR2
 anterior gradient 2
chr1_-_93426998 0.21 ENST00000370310.4
 FAM69A
 family with sequence similarity 69, member A
chr19_-_46272106 0.21 ENST00000560168.1
 SIX5
 SIX homeobox 5
chr9_+_6328338 0.21 ENST00000344545.5
 TPD52L3
 tumor protein D52-like 3
chr12_-_122985494 0.20 ENST00000336229.4
 ZCCHC8
 zinc finger, CCHC domain containing 8
chr21_+_46875424 0.20 ENST00000359759.4
 COL18A1
 collagen, type XVIII, alpha 1
chr16_+_3096638 0.20 ENST00000336577.4
 MMP25
 matrix metallopeptidase 25
chr19_+_14142535 0.20 ENST00000263379.2
 IL27RA
 interleukin 27 receptor, alpha
chr3_-_183967296 0.20 ENST00000455059.1
ENST00000445626.2
 ALG3
 ALG3, alpha-1,3- mannosyltransferase
chr7_-_19184929 0.20 ENST00000275461.3
 FERD3L
 Fer3-like bHLH transcription factor
chr6_-_29527702 0.19 ENST00000377050.4
 UBD
 ubiquitin D
chr11_+_7597639 0.19 ENST00000533792.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_+_50497784 0.19 ENST00000548814.1
 GPD1
 glycerol-3-phosphate dehydrogenase 1 (soluble)
chr1_-_155959853 0.19 ENST00000462460.2
ENST00000368316.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_+_90077680 0.18 ENST00000390270.2
 IGKV3D-20
 immunoglobulin kappa variable 3D-20
chr9_-_124990680 0.18 ENST00000541397.2
ENST00000560485.1
 LHX6
 LIM homeobox 6
chr6_-_31550192 0.18 ENST00000429299.2
ENST00000446745.2
 LTB
 lymphotoxin beta (TNF superfamily, member 3)
chr19_+_41222998 0.18 ENST00000263370.2
 ITPKC
 inositol-trisphosphate 3-kinase C
chr16_-_75498553 0.18 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
 TMEM170A
RP11-77K12.1
 transmembrane protein 170A
Uncharacterized protein
chr4_-_74864386 0.17 ENST00000296027.4
 CXCL5
 chemokine (C-X-C motif) ligand 5
chr2_-_89247338 0.17 ENST00000496168.1
 IGKV1-5
 immunoglobulin kappa variable 1-5
chr16_-_88717423 0.17 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
 CYBA
 cytochrome b-245, alpha polypeptide
chr14_+_103589789 0.17 ENST00000558056.1
ENST00000560869.1
 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
chrX_-_40594755 0.17 ENST00000324817.1
 MED14
 mediator complex subunit 14
chr15_+_42131011 0.17 ENST00000458483.1
 PLA2G4B
 phospholipase A2, group IVB (cytosolic)
chr6_+_135502408 0.17 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
 MYB
 v-myb avian myeloblastosis viral oncogene homolog
chr6_+_151042224 0.17 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_+_102314161 0.16 ENST00000425019.1
 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
chr10_+_104154229 0.16 ENST00000428099.1
ENST00000369966.3
 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_+_42984330 0.16 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
 HNF4A
 hepatocyte nuclear factor 4, alpha
chr12_-_117537240 0.15 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
 TESC
 tescalcin
chr7_-_126892303 0.15 ENST00000358373.3
 GRM8
 glutamate receptor, metabotropic 8
chr14_-_24658053 0.15 ENST00000354464.6
 IPO4
 importin 4
chr4_-_76957214 0.15 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chr12_+_56211703 0.15 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
 ORMDL2
 ORM1-like 2 (S. cerevisiae)
chr14_-_69446034 0.15 ENST00000193403.6
 ACTN1
 actinin, alpha 1
chr7_-_98741714 0.15 ENST00000361125.1
 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
chr9_-_34637806 0.15 ENST00000477726.1
 SIGMAR1
 sigma non-opioid intracellular receptor 1
chr21_-_34915147 0.14 ENST00000381831.3
ENST00000381839.3
 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr1_+_156117149 0.14 ENST00000435124.1
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_-_220094031 0.14 ENST00000443140.1
ENST00000432520.1
ENST00000409618.1
 ATG9A
 autophagy related 9A
chr22_+_46731596 0.14 ENST00000381019.3
 TRMU
 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr2_-_220094294 0.13 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
 ATG9A
 autophagy related 9A
chr1_+_144339738 0.13 ENST00000538264.1
 AL592284.1
 Protein LOC642441
chr12_+_7055631 0.13 ENST00000543115.1
ENST00000399448.1
 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
chr14_+_77648167 0.13 ENST00000554346.1
ENST00000298351.4
 TMEM63C
 transmembrane protein 63C
chr7_-_98741642 0.13 ENST00000361368.2
 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
chr1_-_89738528 0.12 ENST00000343435.5
 GBP5
 guanylate binding protein 5
chr16_-_2059748 0.12 ENST00000562103.1
ENST00000431526.1
 ZNF598
 zinc finger protein 598
chr6_-_32821599 0.12 ENST00000354258.4
 TAP1
 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_104893863 0.12 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
 CASP5
 caspase 5, apoptosis-related cysteine peptidase
chr4_-_74904398 0.12 ENST00000296026.4
 CXCL3
 chemokine (C-X-C motif) ligand 3
chr3_-_49142178 0.12 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
 QARS
 glutaminyl-tRNA synthetase
chr3_-_49142504 0.11 ENST00000306125.6
ENST00000420147.2
 QARS
 glutaminyl-tRNA synthetase
chr2_+_90153696 0.11 ENST00000417279.2
 IGKV3D-15
 immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr12_-_7281469 0.11 ENST00000542370.1
ENST00000266560.3
 RBP5
 retinol binding protein 5, cellular
chr1_+_179050512 0.11 ENST00000367627.3
 TOR3A
 torsin family 3, member A
chr5_-_149792295 0.11 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
 CD74
 CD74 molecule, major histocompatibility complex, class II invariant chain
chr20_-_43977055 0.11 ENST00000372733.3
ENST00000537976.1
 SDC4
 syndecan 4
chr9_-_115095883 0.11 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
 PTBP3
 polypyrimidine tract binding protein 3
chr16_+_84209539 0.11 ENST00000569735.1
 DNAAF1
 dynein, axonemal, assembly factor 1
chr12_-_62997214 0.11 ENST00000408887.2
 C12orf61
 chromosome 12 open reading frame 61
chr22_-_38380543 0.11 ENST00000396884.2
 SOX10
 SRY (sex determining region Y)-box 10
chr10_-_108924284 0.10 ENST00000344440.6
ENST00000263054.6
 SORCS1
 sortilin-related VPS10 domain containing receptor 1
chr3_-_119379719 0.10 ENST00000493094.1
 POPDC2
 popeye domain containing 2
chr19_-_49250054 0.10 ENST00000602105.1
ENST00000332955.2
 IZUMO1
 izumo sperm-egg fusion 1
chr20_-_36156125 0.10 ENST00000397135.1
ENST00000397137.1
 BLCAP
 bladder cancer associated protein
chr12_+_53491220 0.10 ENST00000548547.1
ENST00000301464.3
 IGFBP6
 insulin-like growth factor binding protein 6
chr19_+_39390587 0.10 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr7_+_156742399 0.10 ENST00000275820.3
 NOM1
 nucleolar protein with MIF4G domain 1
chr17_+_49337881 0.10 ENST00000225298.7
 UTP18
 UTP18 small subunit (SSU) processome component homolog (yeast)
chr13_-_52027134 0.10 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6
 integrator complex subunit 6
chr5_-_35230434 0.10 ENST00000504500.1
 PRLR
 prolactin receptor
chr19_-_4831701 0.09 ENST00000248244.5
 TICAM1
 toll-like receptor adaptor molecule 1
chr2_-_113993020 0.09 ENST00000465084.1
 PAX8
 paired box 8
chrX_-_17878827 0.09 ENST00000360011.1
 RAI2
 retinoic acid induced 2
chr2_-_68694390 0.09 ENST00000377957.3
 FBXO48
 F-box protein 48
chr19_+_4229495 0.09 ENST00000221847.5
 EBI3
 Epstein-Barr virus induced 3
chr2_-_89310012 0.09 ENST00000493819.1
 IGKV1-9
 immunoglobulin kappa variable 1-9
chr19_+_41256764 0.09 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
 SNRPA
 small nuclear ribonucleoprotein polypeptide A
chr11_+_119039414 0.09 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
 NLRX1
 NLR family member X1
chr20_-_36156293 0.09 ENST00000373537.2
ENST00000414542.2
 BLCAP
 bladder cancer associated protein
chr16_+_84209738 0.09 ENST00000564928.1
 DNAAF1
 dynein, axonemal, assembly factor 1
chr1_+_63833261 0.09 ENST00000371108.4
 ALG6
 ALG6, alpha-1,3-glucosyltransferase
chr3_+_101280677 0.09 ENST00000309922.6
ENST00000495642.1
 TRMT10C
 tRNA methyltransferase 10 homolog C (S. cerevisiae)
chr2_+_16080659 0.09 ENST00000281043.3
 MYCN
 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr14_+_37667230 0.09 ENST00000556451.1
ENST00000556753.1
ENST00000396294.2
 MIPOL1
 mirror-image polydactyly 1
chrX_+_115567767 0.08 ENST00000371900.4
 SLC6A14
 solute carrier family 6 (amino acid transporter), member 14
chr14_-_35873856 0.08 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr12_-_76425368 0.08 ENST00000602540.1
 PHLDA1
 pleckstrin homology-like domain, family A, member 1
chr7_+_107384579 0.08 ENST00000222597.2
ENST00000415884.2
 CBLL1
 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr9_-_115095123 0.08 ENST00000458258.1
 PTBP3
 polypyrimidine tract binding protein 3
chr21_+_34638656 0.08 ENST00000290200.2
 IL10RB
 interleukin 10 receptor, beta
chr10_+_70587279 0.08 ENST00000298596.6
ENST00000399169.4
ENST00000399165.4
ENST00000399162.2
 STOX1
 storkhead box 1
chr9_-_136344197 0.08 ENST00000414172.1
ENST00000371897.4
 SLC2A6
 solute carrier family 2 (facilitated glucose transporter), member 6
chr2_+_173940668 0.08 ENST00000375213.3
 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
chr16_+_67571351 0.08 ENST00000428437.2
ENST00000569253.1
 FAM65A
 family with sequence similarity 65, member A
chr4_+_74702214 0.08 ENST00000226317.5
ENST00000515050.1
 CXCL6
 chemokine (C-X-C motif) ligand 6
chr4_-_185395672 0.08 ENST00000393593.3
 IRF2
 interferon regulatory factor 2
chr16_+_50730910 0.07 ENST00000300589.2
 NOD2
 nucleotide-binding oligomerization domain containing 2
chr2_+_114647504 0.07 ENST00000263238.2
 ACTR3
 ARP3 actin-related protein 3 homolog (yeast)
chr22_+_22676808 0.07 ENST00000390290.2
 IGLV1-51
 immunoglobulin lambda variable 1-51
chr2_+_238600933 0.07 ENST00000420665.1
ENST00000392000.4
 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
chr5_+_49963239 0.07 ENST00000505554.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr15_-_73661605 0.07 ENST00000261917.3
 HCN4
 hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr11_-_66313699 0.07 ENST00000526986.1
ENST00000310442.3
 ZDHHC24
 zinc finger, DHHC-type containing 24
chr19_+_58193337 0.07 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
 ZNF551
 zinc finger protein 551
chr1_-_62190793 0.07 ENST00000371177.2
ENST00000606498.1
 TM2D1
 TM2 domain containing 1
chr1_-_6453426 0.07 ENST00000545482.1
 ACOT7
 acyl-CoA thioesterase 7
chr6_+_29910301 0.07 ENST00000376809.5
ENST00000376802.2
 HLA-A
 major histocompatibility complex, class I, A
chr15_+_52311398 0.07 ENST00000261845.5
 MAPK6
 mitogen-activated protein kinase 6
chr12_-_40013553 0.07 ENST00000308666.3
 ABCD2
 ATP-binding cassette, sub-family D (ALD), member 2
chr16_+_88636789 0.07 ENST00000301011.5
ENST00000452588.2
 ZC3H18
 zinc finger CCCH-type containing 18
chr10_-_18948156 0.07 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
 ARL5B-AS1
 ARL5B antisense RNA 1
chr2_-_29093132 0.07 ENST00000306108.5
 TRMT61B
 tRNA methyltransferase 61 homolog B (S. cerevisiae)
chr9_+_130547958 0.06 ENST00000421939.1
ENST00000373265.2
 CDK9
 cyclin-dependent kinase 9
chr2_+_202047843 0.06 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr19_+_35842445 0.06 ENST00000246553.2
 FFAR1
 free fatty acid receptor 1
chr6_-_29399744 0.06 ENST00000377154.1
 OR5V1
 olfactory receptor, family 5, subfamily V, member 1
chr17_-_6338399 0.06 ENST00000570584.1
ENST00000574913.1
ENST00000571740.1
ENST00000575265.1
ENST00000574506.1
 AIPL1
 aryl hydrocarbon receptor interacting protein-like 1
chr2_-_177502659 0.06 ENST00000295549.4
 AC017048.3
 long intergenic non-protein coding RNA 1116
chr2_+_202047596 0.06 ENST00000286186.6
ENST00000360132.3
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr1_+_201979645 0.06 ENST00000367284.5
ENST00000367283.3
 ELF3
 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr13_+_97928395 0.06 ENST00000445661.2
 MBNL2
 muscleblind-like splicing regulator 2
chr9_-_115095851 0.06 ENST00000343327.2
 PTBP3
 polypyrimidine tract binding protein 3
chr4_+_72897521 0.05 ENST00000308744.6
ENST00000344413.5
 NPFFR2
 neuropeptide FF receptor 2
chr1_+_165796753 0.05 ENST00000367879.4
 UCK2
 uridine-cytidine kinase 2
chr5_+_150591678 0.05 ENST00000523466.1
 GM2A
 GM2 ganglioside activator
chr18_-_31802282 0.05 ENST00000535475.1
 NOL4
 nucleolar protein 4
chr2_+_63277927 0.05 ENST00000282549.2
 OTX1
 orthodenticle homeobox 1
chr9_-_139927462 0.05 ENST00000314412.6
 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr3_+_93698974 0.05 ENST00000535334.1
ENST00000478400.1
ENST00000303097.7
ENST00000394222.3
ENST00000471138.1
ENST00000539730.1
 ARL13B
 ADP-ribosylation factor-like 13B
chr17_+_80477571 0.05 ENST00000335255.5
 FOXK2
 forkhead box K2
chr14_+_37667118 0.05 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
 MIPOL1
 mirror-image polydactyly 1
chr18_-_31802056 0.05 ENST00000538587.1
 NOL4
 nucleolar protein 4
chr1_-_235813290 0.05 ENST00000391854.2
 GNG4
 guanine nucleotide binding protein (G protein), gamma 4
chr15_-_51058005 0.05 ENST00000261854.5
 SPPL2A
 signal peptide peptidase like 2A
chr1_+_202385953 0.05 ENST00000466968.1
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr3_+_9932238 0.05 ENST00000307768.4
 JAGN1
 jagunal homolog 1 (Drosophila)
chr3_-_139108475 0.04 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
 COPB2
 coatomer protein complex, subunit beta 2 (beta prime)
chr19_+_35940486 0.04 ENST00000246549.2
 FFAR2
 free fatty acid receptor 2
chr22_-_41252962 0.04 ENST00000216218.3
 ST13
 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 0.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 5.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.5 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.2 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 1.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.5 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0009624 response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 1.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.6 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:1901858 cellular response to nitrosative stress(GO:0071500) regulation of mitochondrial DNA metabolic process(GO:1901858)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 1.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 5.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)