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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RELA

Z-value: 0.70

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430251_65430399-0.621.0e-01Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_69064300 0.77 ENST00000342771.4
 AUTS2
 autism susceptibility candidate 2
chr6_+_30850697 0.63 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr17_-_56492989 0.62 ENST00000583753.1
 RNF43
 ring finger protein 43
chr12_-_28124903 0.61 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH
 parathyroid hormone-like hormone
chr1_+_46640750 0.60 ENST00000372003.1
 TSPAN1
 tetraspanin 1
chr14_-_35873856 0.57 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr1_-_209825674 0.56 ENST00000367030.3
ENST00000356082.4
 LAMB3
 laminin, beta 3
chr1_-_209979375 0.52 ENST00000367021.3
 IRF6
 interferon regulatory factor 6
chr11_+_18287721 0.51 ENST00000356524.4
 SAA1
 serum amyloid A1
chr11_+_18287801 0.50 ENST00000532858.1
ENST00000405158.2
 SAA1
 serum amyloid A1
chr19_+_45504688 0.47 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
 RELB
 v-rel avian reticuloendotheliosis viral oncogene homolog B
chr4_-_76944621 0.47 ENST00000306602.1
 CXCL10
 chemokine (C-X-C motif) ligand 10
chr6_+_138188551 0.44 ENST00000237289.4
ENST00000433680.1
 TNFAIP3
 tumor necrosis factor, alpha-induced protein 3
chr1_-_186649543 0.43 ENST00000367468.5
 PTGS2
 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr16_+_67465016 0.43 ENST00000326152.5
 HSD11B2
 hydroxysteroid (11-beta) dehydrogenase 2
chr2_+_17721920 0.43 ENST00000295156.4
 VSNL1
 visinin-like 1
chr2_+_163175394 0.42 ENST00000446271.1
ENST00000429691.2
 GCA
 grancalcin, EF-hand calcium binding protein
chr14_+_61789382 0.42 ENST00000555082.1
 PRKCH
 protein kinase C, eta
chr11_+_1860832 0.42 ENST00000252898.7
 TNNI2
 troponin I type 2 (skeletal, fast)
chr11_+_1860682 0.42 ENST00000381906.1
 TNNI2
 troponin I type 2 (skeletal, fast)
chr6_-_136847099 0.38 ENST00000438100.2
 MAP7
 microtubule-associated protein 7
chr11_-_72492878 0.34 ENST00000535054.1
ENST00000545082.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr11_-_72492903 0.34 ENST00000537947.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr19_-_4338838 0.33 ENST00000594605.1
 STAP2
 signal transducing adaptor family member 2
chr19_-_4338783 0.33 ENST00000601482.1
ENST00000600324.1
 STAP2
 signal transducing adaptor family member 2
chr2_-_74669009 0.32 ENST00000272430.5
 RTKN
 rhotekin
chr19_+_41281060 0.32 ENST00000594436.1
ENST00000597784.1
 MIA
 melanoma inhibitory activity
chr11_+_102188224 0.31 ENST00000263464.3
 BIRC3
 baculoviral IAP repeat containing 3
chr5_-_141257954 0.30 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
 PCDH1
 protocadherin 1
chr19_+_41222998 0.29 ENST00000263370.2
 ITPKC
 inositol-trisphosphate 3-kinase C
chr1_-_209824643 0.28 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr3_+_113666748 0.28 ENST00000330212.3
ENST00000498275.1
 ZDHHC23
 zinc finger, DHHC-type containing 23
chr2_-_163175133 0.28 ENST00000421365.2
ENST00000263642.2
 IFIH1
 interferon induced with helicase C domain 1
chr9_-_117568365 0.27 ENST00000374045.4
 TNFSF15
 tumor necrosis factor (ligand) superfamily, member 15
chr11_+_34642656 0.26 ENST00000257831.3
ENST00000450654.2
 EHF
 ets homologous factor
chr11_+_10476851 0.26 ENST00000396553.2
 AMPD3
 adenosine monophosphate deaminase 3
chr2_+_64681641 0.25 ENST00000409537.2
 LGALSL
 lectin, galactoside-binding-like
chr4_+_103422471 0.25 ENST00000226574.4
ENST00000394820.4
 NFKB1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_+_106534192 0.25 ENST00000369091.2
ENST00000369096.4
 PRDM1
 PR domain containing 1, with ZNF domain
chr7_-_22396533 0.24 ENST00000344041.6
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_24645807 0.24 ENST00000361548.4
 GRHL3
 grainyhead-like 3 (Drosophila)
chr11_+_102188272 0.23 ENST00000532808.1
 BIRC3
 baculoviral IAP repeat containing 3
chr10_+_104154229 0.23 ENST00000428099.1
ENST00000369966.3
 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_-_124990680 0.23 ENST00000541397.2
ENST00000560485.1
 LHX6
 LIM homeobox 6
chr14_-_22005018 0.22 ENST00000546363.1
 SALL2
 spalt-like transcription factor 2
chr1_+_24646002 0.22 ENST00000356046.2
 GRHL3
 grainyhead-like 3 (Drosophila)
chr18_-_28742813 0.22 ENST00000257197.3
ENST00000257198.5
 DSC1
 desmocollin 1
chr1_+_26869597 0.22 ENST00000530003.1
 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr4_+_74735102 0.21 ENST00000395761.3
 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr13_+_97874574 0.21 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
 MBNL2
 muscleblind-like splicing regulator 2
chr7_+_150811705 0.21 ENST00000335367.3
 AGAP3
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_+_24645865 0.21 ENST00000342072.4
 GRHL3
 grainyhead-like 3 (Drosophila)
chr6_-_30712313 0.21 ENST00000376377.2
ENST00000259874.5
 IER3
 immediate early response 3
chr19_-_11688447 0.20 ENST00000590420.1
 ACP5
 acid phosphatase 5, tartrate resistant
chr5_-_35230434 0.20 ENST00000504500.1
 PRLR
 prolactin receptor
chr2_+_233925064 0.19 ENST00000359570.5
ENST00000538935.1
 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
chr2_+_61108771 0.19 ENST00000394479.3
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_-_46272106 0.18 ENST00000560168.1
 SIX5
 SIX homeobox 5
chr1_+_6845497 0.18 ENST00000473578.1
ENST00000557126.1
 CAMTA1
 calmodulin binding transcription activator 1
chr19_-_51471362 0.18 ENST00000376853.4
ENST00000424910.2
 KLK6
 kallikrein-related peptidase 6
chr16_+_3096638 0.18 ENST00000336577.4
 MMP25
 matrix metallopeptidase 25
chr14_-_22005062 0.18 ENST00000317492.5
 SALL2
 spalt-like transcription factor 2
chr6_-_31550192 0.17 ENST00000429299.2
ENST00000446745.2
 LTB
 lymphotoxin beta (TNF superfamily, member 3)
chr4_-_185395672 0.17 ENST00000393593.3
 IRF2
 interferon regulatory factor 2
chr19_-_51471381 0.17 ENST00000594641.1
 KLK6
 kallikrein-related peptidase 6
chr12_+_7055631 0.17 ENST00000543115.1
ENST00000399448.1
 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
chr14_+_103243813 0.17 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
 TRAF3
 TNF receptor-associated factor 3
chr7_-_24797032 0.16 ENST00000409970.1
ENST00000409775.3
 DFNA5
 deafness, autosomal dominant 5
chr19_-_51472031 0.16 ENST00000391808.1
 KLK6
 kallikrein-related peptidase 6
chr12_-_24103954 0.16 ENST00000441133.2
ENST00000545921.1
 SOX5
 SRY (sex determining region Y)-box 5
chr1_+_156123359 0.16 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr12_+_11802753 0.16 ENST00000396373.4
 ETV6
 ets variant 6
chr7_-_16844611 0.16 ENST00000401412.1
ENST00000419304.2
 AGR2
 anterior gradient 2
chr1_+_156123318 0.16 ENST00000368285.3
 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_-_100881109 0.16 ENST00000308344.5
 CLDN15
 claudin 15
chr2_+_61108650 0.16 ENST00000295025.8
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr7_-_24797546 0.15 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
 DFNA5
 deafness, autosomal dominant 5
chr4_-_40631859 0.15 ENST00000295971.7
ENST00000319592.4
 RBM47
 RNA binding motif protein 47
chr1_-_205744574 0.15 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr14_+_75536280 0.14 ENST00000238686.8
 ZC2HC1C
 zinc finger, C2HC-type containing 1C
chr1_-_41950342 0.14 ENST00000372587.4
 EDN2
 endothelin 2
chr19_+_10381769 0.14 ENST00000423829.2
ENST00000588645.1
 ICAM1
 intercellular adhesion molecule 1
chr4_-_74864386 0.14 ENST00000296027.4
 CXCL5
 chemokine (C-X-C motif) ligand 5
chr11_-_75062829 0.14 ENST00000393505.4
 ARRB1
 arrestin, beta 1
chr3_+_6902794 0.14 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
 GRM7
 glutamate receptor, metabotropic 7
chr1_-_205744205 0.14 ENST00000446390.2
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr6_+_135502466 0.13 ENST00000367814.4
 MYB
 v-myb avian myeloblastosis viral oncogene homolog
chr5_-_150460914 0.13 ENST00000389378.2
 TNIP1
 TNFAIP3 interacting protein 1
chrX_+_152907913 0.13 ENST00000370167.4
 DUSP9
 dual specificity phosphatase 9
chr15_+_57884117 0.13 ENST00000267853.5
 MYZAP
 myocardial zonula adherens protein
chr19_-_11688500 0.13 ENST00000433365.2
 ACP5
 acid phosphatase 5, tartrate resistant
chr2_-_209028300 0.13 ENST00000304502.4
 CRYGA
 crystallin, gamma A
chr14_+_75536335 0.13 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
 ZC2HC1C
 zinc finger, C2HC-type containing 1C
chr3_+_111578131 0.12 ENST00000498699.1
 PHLDB2
 pleckstrin homology-like domain, family B, member 2
chr6_+_29691198 0.12 ENST00000440587.2
ENST00000434407.2
 HLA-F
 major histocompatibility complex, class I, F
chr16_+_50730910 0.12 ENST00000300589.2
 NOD2
 nucleotide-binding oligomerization domain containing 2
chr20_-_4795747 0.12 ENST00000379376.2
 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
chr1_+_159796534 0.12 ENST00000289707.5
 SLAMF8
 SLAM family member 8
chr5_-_150460539 0.12 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
 TNIP1
 TNFAIP3 interacting protein 1
chr3_+_111578027 0.12 ENST00000431670.2
ENST00000412622.1
 PHLDB2
 pleckstrin homology-like domain, family B, member 2
chr19_-_4831701 0.12 ENST00000248244.5
 TICAM1
 toll-like receptor adaptor molecule 1
chr1_+_247579451 0.11 ENST00000391828.3
ENST00000366497.2
 NLRP3
 NLR family, pyrin domain containing 3
chr22_-_37545972 0.11 ENST00000216223.5
 IL2RB
 interleukin 2 receptor, beta
chr17_+_40440481 0.11 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
 STAT5A
 signal transducer and activator of transcription 5A
chr7_-_93520191 0.11 ENST00000545378.1
 TFPI2
 tissue factor pathway inhibitor 2
chr1_-_155959853 0.11 ENST00000462460.2
ENST00000368316.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr10_+_18948311 0.11 ENST00000377275.3
 ARL5B
 ADP-ribosylation factor-like 5B
chr11_-_75062730 0.11 ENST00000420843.2
ENST00000360025.3
 ARRB1
 arrestin, beta 1
chr22_-_38380543 0.10 ENST00000396884.2
 SOX10
 SRY (sex determining region Y)-box 10
chr19_+_51728316 0.10 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
 CD33
 CD33 molecule
chr14_+_103589789 0.10 ENST00000558056.1
ENST00000560869.1
 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
chr6_+_29691056 0.10 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
 HLA-F
 major histocompatibility complex, class I, F
chr3_+_53195136 0.10 ENST00000394729.2
ENST00000330452.3
 PRKCD
 protein kinase C, delta
chr1_-_39395165 0.10 ENST00000372985.3
 RHBDL2
 rhomboid, veinlet-like 2 (Drosophila)
chr1_-_155947951 0.10 ENST00000313695.7
ENST00000497907.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_6845384 0.10 ENST00000303635.7
 CAMTA1
 calmodulin binding transcription activator 1
chr4_-_76957214 0.10 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chr1_-_36615051 0.09 ENST00000373163.1
 TRAPPC3
 trafficking protein particle complex 3
chr2_+_234602305 0.09 ENST00000406651.1
 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
chr1_-_36615065 0.09 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
 TRAPPC3
 trafficking protein particle complex 3
chr1_+_111770278 0.09 ENST00000369748.4
 CHI3L2
 chitinase 3-like 2
chr1_+_111770232 0.09 ENST00000369744.2
 CHI3L2
 chitinase 3-like 2
chr21_-_43373999 0.09 ENST00000380486.3
 C2CD2
 C2 calcium-dependent domain containing 2
chr12_+_5019061 0.09 ENST00000382545.3
 KCNA1
 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr15_+_57884086 0.09 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
 GCOM1
 GRINL1A complex locus 1
chr6_+_32121908 0.09 ENST00000375143.2
ENST00000424499.1
 PPT2
 palmitoyl-protein thioesterase 2
chr16_-_66959429 0.09 ENST00000420652.1
ENST00000299759.6
 RRAD
 Ras-related associated with diabetes
chr21_+_34775698 0.09 ENST00000381995.1
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_+_54359854 0.09 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
 DIO1
 deiodinase, iodothyronine, type I
chrX_-_48827976 0.09 ENST00000218176.3
 KCND1
 potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_-_41222775 0.09 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
 ADCK4
 aarF domain containing kinase 4
chr20_+_9494987 0.09 ENST00000427562.2
ENST00000246070.2
 LAMP5
 lysosomal-associated membrane protein family, member 5
chr12_+_72056773 0.09 ENST00000308086.2
 THAP2
 THAP domain containing, apoptosis associated protein 2
chr3_-_111852128 0.09 ENST00000308910.4
 GCSAM
 germinal center-associated, signaling and motility
chr10_+_104155450 0.09 ENST00000471698.1
ENST00000189444.6
 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_+_32121789 0.09 ENST00000437001.2
ENST00000375137.2
 PPT2
 palmitoyl-protein thioesterase 2
chr7_+_89841144 0.09 ENST00000394622.2
ENST00000394632.1
ENST00000426158.1
ENST00000394621.2
ENST00000402625.2
 STEAP2
 STEAP family member 2, metalloreductase
chr19_-_46272462 0.09 ENST00000317578.6
 SIX5
 SIX homeobox 5
chr14_+_93897272 0.08 ENST00000393151.2
 UNC79
 unc-79 homolog (C. elegans)
chr6_-_29527702 0.08 ENST00000377050.4
 UBD
 ubiquitin D
chr1_-_54303949 0.08 ENST00000234725.8
 NDC1
 NDC1 transmembrane nucleoporin
chr7_-_93520259 0.08 ENST00000222543.5
 TFPI2
 tissue factor pathway inhibitor 2
chr3_-_4793274 0.08 ENST00000414938.1
 EGOT
 eosinophil granule ontogeny transcript (non-protein coding)
chr19_+_45251804 0.08 ENST00000164227.5
 BCL3
 B-cell CLL/lymphoma 3
chr9_-_32526184 0.08 ENST00000545044.1
ENST00000379868.1
 DDX58
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr21_+_34775181 0.08 ENST00000290219.6
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr3_+_159706537 0.08 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
 IL12A
 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr19_-_47734448 0.08 ENST00000439096.2
 BBC3
 BCL2 binding component 3
chr6_-_109762344 0.08 ENST00000521072.2
ENST00000424445.2
ENST00000440797.2
 PPIL6
 peptidylprolyl isomerase (cyclophilin)-like 6
chr1_-_94079648 0.08 ENST00000370247.3
 BCAR3
 breast cancer anti-estrogen resistance 3
chr1_+_155657737 0.07 ENST00000471642.2
ENST00000471214.1
 DAP3
 death associated protein 3
chr21_+_34775772 0.07 ENST00000405436.1
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_+_30297306 0.07 ENST00000420746.1
ENST00000513556.1
 TRIM39
TRIM39-RPP21
 tripartite motif containing 39
TRIM39-RPP21 readthrough
chr6_+_160327974 0.07 ENST00000252660.4
 MAS1
 MAS1 oncogene
chr22_+_20748405 0.07 ENST00000400451.2
ENST00000403682.3
ENST00000357502.5
 ZNF74
 zinc finger protein 74
chr1_-_54303934 0.07 ENST00000537333.1
 NDC1
 NDC1 transmembrane nucleoporin
chr1_+_67632083 0.07 ENST00000347310.5
ENST00000371002.1
 IL23R
 interleukin 23 receptor
chr7_+_69064566 0.07 ENST00000403018.2
 AUTS2
 autism susceptibility candidate 2
chr9_-_32526299 0.07 ENST00000379882.1
ENST00000379883.2
 DDX58
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_-_89738528 0.07 ENST00000343435.5
 GBP5
 guanylate binding protein 5
chr4_-_187644930 0.07 ENST00000441802.2
 FAT1
 FAT atypical cadherin 1
chr9_+_98637954 0.07 ENST00000288985.7
 ERCC6L2
 excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2
chr4_-_151936416 0.07 ENST00000510413.1
ENST00000507224.1
 LRBA
 LPS-responsive vesicle trafficking, beach and anchor containing
chr2_+_97202480 0.07 ENST00000357485.3
 ARID5A
 AT rich interactive domain 5A (MRF1-like)
chr19_-_54984354 0.06 ENST00000301200.2
 CDC42EP5
 CDC42 effector protein (Rho GTPase binding) 5
chr1_+_231297798 0.06 ENST00000444294.3
 TRIM67
 tripartite motif containing 67
chr17_+_21191341 0.06 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
 MAP2K3
 mitogen-activated protein kinase kinase 3
chr2_-_136743039 0.06 ENST00000537273.1
 DARS
 aspartyl-tRNA synthetase
chr11_-_58345569 0.06 ENST00000528954.1
ENST00000528489.1
 LPXN
 leupaxin
chr2_-_136743169 0.06 ENST00000264161.4
 DARS
 aspartyl-tRNA synthetase
chr19_+_4229495 0.06 ENST00000221847.5
 EBI3
 Epstein-Barr virus induced 3
chr15_+_26360970 0.06 ENST00000556159.1
ENST00000557523.1
 LINC00929
 long intergenic non-protein coding RNA 929
chr2_+_202047843 0.06 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr7_-_98741714 0.06 ENST00000361125.1
 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
chr2_+_202047596 0.06 ENST00000286186.6
ENST00000360132.3
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr15_+_52311398 0.06 ENST00000261845.5
 MAPK6
 mitogen-activated protein kinase 6
chr12_-_55375622 0.06 ENST00000316577.8
 TESPA1
 thymocyte expressed, positive selection associated 1
chr9_-_140115775 0.06 ENST00000391553.1
ENST00000392827.1
 RNF208
 ring finger protein 208
chr20_+_17207636 0.06 ENST00000262545.2
 PCSK2
 proprotein convertase subtilisin/kexin type 2
chr20_-_36156125 0.06 ENST00000397135.1
ENST00000397137.1
 BLCAP
 bladder cancer associated protein
chr13_+_47127293 0.06 ENST00000311191.6
 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
chr5_+_150591678 0.06 ENST00000523466.1
 GM2A
 GM2 ganglioside activator
chr12_-_323689 0.06 ENST00000428720.1
 SLC6A12
 solute carrier family 6 (neurotransmitter transporter), member 12
chr18_-_12884259 0.06 ENST00000353319.4
ENST00000327283.3
 PTPN2
 protein tyrosine phosphatase, non-receptor type 2
chr14_+_96968707 0.06 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
 PAPOLA
 poly(A) polymerase alpha
chr13_+_47127322 0.06 ENST00000389798.3
 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
chr1_+_6845578 0.05 ENST00000467404.2
ENST00000439411.2
 CAMTA1
 calmodulin binding transcription activator 1
chr6_-_32636145 0.05 ENST00000399084.1
 HLA-DQB1
 major histocompatibility complex, class II, DQ beta 1
chr2_+_97203082 0.05 ENST00000454558.2
 ARID5A
 AT rich interactive domain 5A (MRF1-like)
chr7_-_98741642 0.05 ENST00000361368.2
 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
chr1_-_54304212 0.05 ENST00000540001.1
 NDC1
 NDC1 transmembrane nucleoporin
chr1_-_151319710 0.05 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
 RFX5
 regulatory factor X, 5 (influences HLA class II expression)
chr1_+_44870866 0.05 ENST00000355387.2
ENST00000361799.2
 RNF220
 ring finger protein 220
chr2_+_166428839 0.05 ENST00000342316.4
 CSRNP3
 cysteine-serine-rich nuclear protein 3
chr19_-_4182530 0.05 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
 SIRT6
 sirtuin 6
chr3_-_49131013 0.05 ENST00000424300.1
 QRICH1
 glutamine-rich 1
chr20_-_2451395 0.05 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
 SNRPB
 small nuclear ribonucleoprotein polypeptides B and B1
chr1_-_110613276 0.05 ENST00000369792.4
 ALX3
 ALX homeobox 3
chr1_-_57889687 0.05 ENST00000371236.2
ENST00000371230.1
 DAB1
 Dab, reelin signal transducer, homolog 1 (Drosophila)
chr1_-_153935983 0.05 ENST00000537590.1
ENST00000356205.4
 SLC39A1
 solute carrier family 39 (zinc transporter), member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.3 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.7 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.3 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.5 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.7 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 1.1 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.4 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.0 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.0 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.0 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.0 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.0 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation