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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RFX5

Z-value: 0.21

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Transcription factors associated with RFX5

Gene Symbol Gene ID Gene Info
ENSG00000143390.13 RFX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX5hg19_v2_chr1_-_151319283_1513193140.743.5e-02Click!

Activity profile of RFX5 motif

Sorted Z-values of RFX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_33043703 0.34 ENST00000418931.2
ENST00000535465.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr19_+_45418067 0.22 ENST00000589078.1
ENST00000586638.1
APOC1
apolipoprotein C-I
chr19_+_45417921 0.21 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr6_+_32821924 0.19 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr6_+_32812568 0.15 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_32557610 0.11 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr6_-_32498046 0.10 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr6_+_26440700 0.09 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr6_-_32812420 0.09 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr3_-_169587621 0.07 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr1_+_181003067 0.06 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
MR1
major histocompatibility complex, class I-related
chr6_-_32784687 0.06 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr6_+_26365443 0.06 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr1_+_85527987 0.06 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr11_+_45868957 0.06 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr10_+_82116529 0.05 ENST00000411538.1
ENST00000256039.2
DYDC2
DPY30 domain containing 2
chr3_+_66271410 0.05 ENST00000336733.6
SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr11_-_72433346 0.05 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_+_8008867 0.05 ENST00000309828.4
ENST00000449102.2
EIF3F
eukaryotic translation initiation factor 3, subunit F
chr17_-_19266045 0.05 ENST00000395616.3
B9D1
B9 protein domain 1
chr3_+_66271489 0.04 ENST00000536651.1
SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr9_+_135937365 0.04 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr6_+_26383318 0.04 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr6_-_32634425 0.04 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr16_+_67381263 0.03 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
LRRC36
leucine rich repeat containing 36
chr1_+_150254936 0.03 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr12_-_126467906 0.03 ENST00000507313.1
ENST00000545784.1
LINC00939
long intergenic non-protein coding RNA 939
chr2_-_105030466 0.03 ENST00000449772.1
AC068535.3
AC068535.3
chr11_-_85430088 0.03 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr17_-_19265982 0.03 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr16_+_67381289 0.03 ENST00000435835.3
LRRC36
leucine rich repeat containing 36
chr11_-_6640585 0.02 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1
tripeptidyl peptidase I
chr6_+_26383404 0.02 ENST00000416795.2
ENST00000494184.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr17_-_19265855 0.02 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr8_-_98290087 0.02 ENST00000322128.3
TSPYL5
TSPY-like 5
chr8_-_99306611 0.02 ENST00000341166.3
NIPAL2
NIPA-like domain containing 2
chr1_+_249132462 0.02 ENST00000306562.3
ZNF672
zinc finger protein 672
chr20_+_306177 0.02 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr11_-_118436606 0.02 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr1_-_53608289 0.02 ENST00000371491.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr10_-_82116467 0.02 ENST00000454362.1
DYDC1
DPY30 domain containing 1
chrX_-_40594755 0.01 ENST00000324817.1
MED14
mediator complex subunit 14
chr8_-_99306564 0.01 ENST00000430223.2
NIPAL2
NIPA-like domain containing 2
chr13_-_30424821 0.01 ENST00000380680.4
UBL3
ubiquitin-like 3
chr19_-_51014345 0.01 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
JOSD2
Josephin domain containing 2
chr1_-_27339317 0.01 ENST00000289166.5
FAM46B
family with sequence similarity 46, member B
chr11_-_118436707 0.01 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr3_-_27410847 0.01 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10
NIMA-related kinase 10
chr20_+_306221 0.01 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr6_-_32731299 0.01 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr19_+_19496728 0.01 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr22_+_31518938 0.01 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr6_-_24667180 0.01 ENST00000545995.1
TDP2
tyrosyl-DNA phosphodiesterase 2
chr5_-_55412774 0.01 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr6_-_24666819 0.01 ENST00000341060.3
TDP2
tyrosyl-DNA phosphodiesterase 2
chr6_-_32731243 0.00 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr16_-_74808710 0.00 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr6_-_133079022 0.00 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr19_+_3933579 0.00 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr1_+_46049706 0.00 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr10_-_82116505 0.00 ENST00000372202.1
ENST00000421924.2
ENST00000453477.1
DYDC1
DPY30 domain containing 1
chr2_+_242088963 0.00 ENST00000438799.1
ENST00000402734.1
ENST00000423280.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr6_-_167571817 0.00 ENST00000366834.1
GPR31
G protein-coupled receptor 31
chr4_-_143227088 0.00 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr13_-_47012325 0.00 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr4_-_143226979 0.00 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse