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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RFX7_RFX4_RFX1

Z-value: 0.85

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Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
RFX7
ENSG00000181827.10 RFX7
RFX4
ENSG00000111783.8 RFX4
RFX1
ENSG00000132005.4 RFX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX7hg19_v2_chr15_-_56535464_56535521-0.611.1e-01Click!
RFX1hg19_v2_chr19_-_14117074_14117141-0.393.5e-01Click!
RFX4hg19_v2_chr12_+_106976678_106976708,
hg19_v2_chr12_+_107078474_107078533		-0.019.8e-01Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_50316517 0.66 ENST00000313777.4
ENST00000445575.2
 FUZ
 fuzzy planar cell polarity protein
chr19_-_50316423 0.62 ENST00000528094.1
ENST00000526575.1
 FUZ
 fuzzy planar cell polarity protein
chr19_-_50316489 0.60 ENST00000533418.1
 FUZ
 fuzzy planar cell polarity protein
chr1_-_72748417 0.53 ENST00000357731.5
 NEGR1
 neuronal growth regulator 1
chr2_-_190044480 0.46 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr1_-_109655355 0.41 ENST00000369945.3
 C1orf194
 chromosome 1 open reading frame 194
chr14_-_61116168 0.41 ENST00000247182.6
 SIX1
 SIX homeobox 1
chr20_-_30310797 0.40 ENST00000422920.1
 BCL2L1
 BCL2-like 1
chr11_-_6426635 0.40 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr20_-_30311703 0.38 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
 BCL2L1
 BCL2-like 1
chr19_+_48972459 0.34 ENST00000427476.1
 CYTH2
 cytohesin 2
chr11_-_70507901 0.33 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr19_-_45953983 0.32 ENST00000592083.1
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr17_-_15244894 0.30 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
 TEKT3
 tektin 3
chr2_+_95537170 0.28 ENST00000295201.4
 TEKT4
 tektin 4
chr2_-_62081148 0.25 ENST00000404929.1
 FAM161A
 family with sequence similarity 161, member A
chr2_-_62081254 0.25 ENST00000405894.3
 FAM161A
 family with sequence similarity 161, member A
chr2_-_63815628 0.24 ENST00000409562.3
 WDPCP
 WD repeat containing planar cell polarity effector
chr20_-_44718538 0.24 ENST00000290231.6
ENST00000372291.3
 NCOA5
 nuclear receptor coactivator 5
chr22_-_43485381 0.23 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
 TTLL1
 tubulin tyrosine ligase-like family, member 1
chr3_-_128712906 0.23 ENST00000511438.1
 KIAA1257
 KIAA1257
chr19_+_55996565 0.23 ENST00000587400.1
 NAT14
 N-acetyltransferase 14 (GCN5-related, putative)
chr14_-_88459182 0.22 ENST00000544807.2
 GALC
 galactosylceramidase
chr4_+_26585686 0.22 ENST00000505206.1
ENST00000511789.1
 TBC1D19
 TBC1 domain family, member 19
chr4_-_2420335 0.22 ENST00000503000.1
 ZFYVE28
 zinc finger, FYVE domain containing 28
chr9_-_138391692 0.22 ENST00000429260.2
 C9orf116
 chromosome 9 open reading frame 116
chr10_+_25305524 0.22 ENST00000524413.1
ENST00000376356.4
 THNSL1
 threonine synthase-like 1 (S. cerevisiae)
chr1_+_183605200 0.22 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr11_-_70507867 0.21 ENST00000412252.1
ENST00000409161.1
ENST00000409530.1
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr19_-_40324255 0.21 ENST00000593685.1
ENST00000600611.1
 DYRK1B
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_+_16308659 0.21 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
 AP1M1
 adaptor-related protein complex 1, mu 1 subunit
chr4_+_26585538 0.21 ENST00000264866.4
 TBC1D19
 TBC1 domain family, member 19
chr16_-_72127456 0.21 ENST00000562153.1
 TXNL4B
 thioredoxin-like 4B
chr14_-_88459503 0.20 ENST00000393568.4
ENST00000261304.2
 GALC
 galactosylceramidase
chr1_+_155829286 0.20 ENST00000368324.4
 SYT11
 synaptotagmin XI
chr19_-_51014460 0.20 ENST00000595669.1
 JOSD2
 Josephin domain containing 2
chr3_+_99357319 0.20 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
 COL8A1
 collagen, type VIII, alpha 1
chr12_-_76478686 0.20 ENST00000261182.8
 NAP1L1
 nucleosome assembly protein 1-like 1
chr1_-_109655377 0.19 ENST00000369948.3
 C1orf194
 chromosome 1 open reading frame 194
chr15_+_55700741 0.18 ENST00000569691.1
 C15orf65
 chromosome 15 open reading frame 65
chr22_+_35776828 0.18 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr8_+_13424352 0.18 ENST00000297324.4
 C8orf48
 chromosome 8 open reading frame 48
chr22_-_32555275 0.18 ENST00000382097.3
 C22orf42
 chromosome 22 open reading frame 42
chr19_+_55996316 0.18 ENST00000205194.4
 NAT14
 N-acetyltransferase 14 (GCN5-related, putative)
chr20_+_12989596 0.18 ENST00000434210.1
ENST00000399002.2
 SPTLC3
 serine palmitoyltransferase, long chain base subunit 3
chr17_-_64187973 0.17 ENST00000583358.1
ENST00000392769.2
 CEP112
 centrosomal protein 112kDa
chr17_-_64188177 0.17 ENST00000535342.2
 CEP112
 centrosomal protein 112kDa
chr12_-_58329819 0.17 ENST00000551421.1
 RP11-620J15.3
 RP11-620J15.3
chr11_+_71791693 0.17 ENST00000289488.2
ENST00000447974.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr6_+_89790459 0.17 ENST00000369472.1
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr2_-_63815860 0.16 ENST00000272321.7
ENST00000431065.1
 WDPCP
 WD repeat containing planar cell polarity effector
chr8_+_10530155 0.16 ENST00000521818.1
 C8orf74
 chromosome 8 open reading frame 74
chr2_+_170550944 0.16 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
 PHOSPHO2
KLHL23
 phosphatase, orphan 2
kelch-like family member 23
chr6_-_167275991 0.16 ENST00000510118.1
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr20_+_17550489 0.16 ENST00000246069.7
 DSTN
 destrin (actin depolymerizing factor)
chr5_+_75699149 0.16 ENST00000379730.3
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr19_+_507299 0.16 ENST00000359315.5
 TPGS1
 tubulin polyglutamylase complex subunit 1
chr4_-_156787425 0.15 ENST00000537611.2
 ASIC5
 acid-sensing (proton-gated) ion channel family member 5
chr14_-_22005018 0.15 ENST00000546363.1
 SALL2
 spalt-like transcription factor 2
chr19_-_46974664 0.15 ENST00000438932.2
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr1_-_85155939 0.15 ENST00000603677.1
 SSX2IP
 synovial sarcoma, X breakpoint 2 interacting protein
chrX_-_64254587 0.15 ENST00000337990.2
 ZC4H2
 zinc finger, C4H2 domain containing
chr19_-_46974741 0.15 ENST00000313683.10
ENST00000602246.1
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr6_-_167276033 0.15 ENST00000503859.1
ENST00000506565.1
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_+_67700673 0.15 ENST00000403458.4
ENST00000602365.1
 C16orf86
 chromosome 16 open reading frame 86
chr16_+_20912382 0.15 ENST00000396052.2
 LYRM1
 LYR motif containing 1
chr17_-_56296580 0.15 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
 MKS1
 Meckel syndrome, type 1
chr1_-_85156216 0.15 ENST00000342203.3
ENST00000370612.4
 SSX2IP
 synovial sarcoma, X breakpoint 2 interacting protein
chr1_-_85156090 0.15 ENST00000605755.1
ENST00000437941.2
 SSX2IP
 synovial sarcoma, X breakpoint 2 interacting protein
chr15_-_55790515 0.15 ENST00000448430.2
ENST00000457155.2
 DYX1C1
 dyslexia susceptibility 1 candidate 1
chr3_-_105588231 0.15 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr19_-_40324767 0.14 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
 DYRK1B
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr10_+_15001430 0.14 ENST00000407572.1
 MEIG1
 meiosis/spermiogenesis associated 1
chr16_+_20912075 0.14 ENST00000219168.4
 LYRM1
 LYR motif containing 1
chr17_+_48585794 0.14 ENST00000576179.1
ENST00000419930.1
 MYCBPAP
 MYCBP associated protein
chr17_+_42977122 0.14 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
 FAM187A
CCDC103
 family with sequence similarity 187, member A
coiled-coil domain containing 103
chr12_+_107168418 0.14 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
 RIC8B
 RIC8 guanine nucleotide exchange factor B
chr1_-_36915880 0.14 ENST00000445843.3
 OSCP1
 organic solute carrier partner 1
chr14_+_61447927 0.14 ENST00000451406.1
 SLC38A6
 solute carrier family 38, member 6
chr11_+_133938820 0.14 ENST00000299106.4
ENST00000529443.2
 JAM3
 junctional adhesion molecule 3
chr16_+_3550924 0.13 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
 CLUAP1
 clusterin associated protein 1
chr1_-_36916066 0.13 ENST00000315643.9
 OSCP1
 organic solute carrier partner 1
chr11_+_71791359 0.13 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr14_+_61447832 0.13 ENST00000354886.2
ENST00000267488.4
 SLC38A6
 solute carrier family 38, member 6
chrX_+_102883620 0.13 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr11_-_62521614 0.13 ENST00000527994.1
ENST00000394807.3
 ZBTB3
 zinc finger and BTB domain containing 3
chr13_+_24153488 0.13 ENST00000382258.4
ENST00000382263.3
 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
chr2_+_242089046 0.13 ENST00000407025.1
ENST00000272983.8
 PPP1R7
 protein phosphatase 1, regulatory subunit 7
chr2_+_242088963 0.13 ENST00000438799.1
ENST00000402734.1
ENST00000423280.1
 PPP1R7
 protein phosphatase 1, regulatory subunit 7
chr4_+_6784401 0.13 ENST00000425103.1
ENST00000307659.5
 KIAA0232
 KIAA0232
chr4_+_153457404 0.13 ENST00000604157.1
ENST00000594836.1
 MIR4453
 microRNA 4453
chr1_-_109968973 0.13 ENST00000271308.4
ENST00000538610.1
 PSMA5
 proteasome (prosome, macropain) subunit, alpha type, 5
chr11_-_66104237 0.12 ENST00000530056.1
 RIN1
 Ras and Rab interactor 1
chr4_+_15004165 0.12 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
 CPEB2
 cytoplasmic polyadenylation element binding protein 2
chr1_+_161068179 0.12 ENST00000368011.4
ENST00000392192.2
 KLHDC9
 kelch domain containing 9
chr1_+_39456895 0.12 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
 AKIRIN1
 akirin 1
chr11_+_133938955 0.12 ENST00000534549.1
ENST00000441717.3
 JAM3
 junctional adhesion molecule 3
chr4_-_89619386 0.12 ENST00000323061.5
 NAP1L5
 nucleosome assembly protein 1-like 5
chr1_+_11866207 0.12 ENST00000312413.6
ENST00000346436.6
 CLCN6
 chloride channel, voltage-sensitive 6
chr11_+_71791803 0.12 ENST00000539271.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr6_+_112408768 0.12 ENST00000368656.2
ENST00000604268.1
 FAM229B
 family with sequence similarity 229, member B
chr2_-_175869936 0.12 ENST00000409900.3
 CHN1
 chimerin 1
chr4_-_2420357 0.12 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
 ZFYVE28
 zinc finger, FYVE domain containing 28
chr1_-_36916011 0.12 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
 OSCP1
 organic solute carrier partner 1
chr20_-_45981138 0.12 ENST00000446994.2
 ZMYND8
 zinc finger, MYND-type containing 8
chr2_+_61293021 0.12 ENST00000402291.1
 KIAA1841
 KIAA1841
chr6_-_44265446 0.11 ENST00000371503.3
 TCTE1
 t-complex-associated-testis-expressed 1
chr7_+_158649242 0.11 ENST00000407559.3
 WDR60
 WD repeat domain 60
chr15_-_55700216 0.11 ENST00000569205.1
 CCPG1
 cell cycle progression 1
chr5_+_178986693 0.11 ENST00000437570.2
ENST00000393438.2
 RUFY1
 RUN and FYVE domain containing 1
chr15_-_55700457 0.11 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
 CCPG1
 cell cycle progression 1
chr3_+_191046810 0.11 ENST00000392455.3
ENST00000392456.3
 CCDC50
 coiled-coil domain containing 50
chr2_-_230579185 0.11 ENST00000341772.4
 DNER
 delta/notch-like EGF repeat containing
chr6_+_52285131 0.11 ENST00000433625.2
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr6_-_38607673 0.11 ENST00000481247.1
 BTBD9
 BTB (POZ) domain containing 9
chrX_+_135251835 0.11 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr2_-_175870085 0.10 ENST00000409156.3
 CHN1
 chimerin 1
chr13_-_44361025 0.10 ENST00000261488.6
 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
chr12_-_54867352 0.10 ENST00000305879.5
 GTSF1
 gametocyte specific factor 1
chr20_+_42219559 0.10 ENST00000373030.3
ENST00000373039.4
 IFT52
 intraflagellar transport 52 homolog (Chlamydomonas)
chr12_-_49582978 0.10 ENST00000301071.7
 TUBA1A
 tubulin, alpha 1a
chr12_-_76478446 0.10 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
 NAP1L1
 nucleosome assembly protein 1-like 1
chr12_-_76478417 0.10 ENST00000552342.1
 NAP1L1
 nucleosome assembly protein 1-like 1
chr9_-_130635741 0.10 ENST00000223836.10
 AK1
 adenylate kinase 1
chr15_+_93447675 0.10 ENST00000536619.1
 CHD2
 chromodomain helicase DNA binding protein 2
chr19_+_46850251 0.10 ENST00000012443.4
 PPP5C
 protein phosphatase 5, catalytic subunit
chr19_+_16308711 0.10 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
 AP1M1
 adaptor-related protein complex 1, mu 1 subunit
chr4_-_170533723 0.10 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
 NEK1
 NIMA-related kinase 1
chr20_+_17550691 0.10 ENST00000474024.1
 DSTN
 destrin (actin depolymerizing factor)
chr1_-_159893507 0.10 ENST00000368096.1
 TAGLN2
 transgelin 2
chr1_+_144220127 0.10 ENST00000369373.5
 NBPF8
 neuroblastoma breakpoint family, member 8
chr5_-_133702761 0.10 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
 CDKL3
 cyclin-dependent kinase-like 3
chr11_+_69455855 0.10 ENST00000227507.2
ENST00000536559.1
 CCND1
 cyclin D1
chr14_+_88852059 0.09 ENST00000045347.7
 SPATA7
 spermatogenesis associated 7
chr20_+_306177 0.09 ENST00000544632.1
 SOX12
 SRY (sex determining region Y)-box 12
chr12_+_107168342 0.09 ENST00000392837.4
 RIC8B
 RIC8 guanine nucleotide exchange factor B
chr7_+_12726474 0.09 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
 ARL4A
 ADP-ribosylation factor-like 4A
chrX_+_85969626 0.09 ENST00000484479.1
 DACH2
 dachshund homolog 2 (Drosophila)
chr11_+_6411670 0.09 ENST00000530395.1
ENST00000527275.1
 SMPD1
 sphingomyelin phosphodiesterase 1, acid lysosomal
chr10_-_28623368 0.09 ENST00000441595.2
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_76478386 0.09 ENST00000535020.2
 NAP1L1
 nucleosome assembly protein 1-like 1
chr16_+_284788 0.09 ENST00000301679.2
ENST00000419173.1
ENST00000426695.1
ENST00000438220.1
ENST00000447499.1
ENST00000453430.1
ENST00000442458.2
ENST00000449945.1
ENST00000420046.1
ENST00000301678.3
ENST00000450082.2
ENST00000420500.1
 ITFG3
 integrin alpha FG-GAP repeat containing 3
chr15_-_55700522 0.09 ENST00000564092.1
ENST00000310958.6
 CCPG1
 cell cycle progression 1
chr19_+_1249869 0.09 ENST00000591446.2
 MIDN
 midnolin
chr22_+_45809560 0.09 ENST00000342894.3
ENST00000538017.1
 RIBC2
 RIB43A domain with coiled-coils 2
chr6_+_52285046 0.09 ENST00000371068.5
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr12_+_48577366 0.09 ENST00000316554.3
 C12orf68
 chromosome 12 open reading frame 68
chr3_-_197676740 0.09 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
 IQCG
 IQ motif containing G
chr19_+_46850320 0.09 ENST00000391919.1
 PPP5C
 protein phosphatase 5, catalytic subunit
chr19_-_10679644 0.09 ENST00000393599.2
 CDKN2D
 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr2_+_220110177 0.09 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
 STK16
 serine/threonine kinase 16
chr3_+_9958758 0.09 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
 IL17RC
 interleukin 17 receptor C
chr19_-_6393216 0.09 ENST00000595047.1
 GTF2F1
 general transcription factor IIF, polypeptide 1, 74kDa
chr17_-_55911970 0.09 ENST00000581805.1
ENST00000580960.1
 RP11-60A24.3
 RP11-60A24.3
chr3_-_105587879 0.09 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr15_-_52944231 0.09 ENST00000546305.2
 FAM214A
 family with sequence similarity 214, member A
chr6_-_130031358 0.09 ENST00000368149.2
 ARHGAP18
 Rho GTPase activating protein 18
chr1_+_211432775 0.09 ENST00000419091.2
 RCOR3
 REST corepressor 3
chr2_+_173940163 0.08 ENST00000539448.1
 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
chr17_-_16472483 0.08 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
 ZNF287
 zinc finger protein 287
chrX_+_135252050 0.08 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chrX_+_47444613 0.08 ENST00000445623.1
 TIMP1
 TIMP metallopeptidase inhibitor 1
chr2_-_153032484 0.08 ENST00000263904.4
 STAM2
 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr12_-_105630016 0.08 ENST00000258530.3
 APPL2
 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr6_+_89790490 0.08 ENST00000336032.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr15_+_49447947 0.08 ENST00000327171.3
ENST00000560654.1
 GALK2
 galactokinase 2
chr16_-_29757272 0.08 ENST00000329410.3
 C16orf54
 chromosome 16 open reading frame 54
chr8_+_144816303 0.08 ENST00000533004.1
 FAM83H-AS1
 FAM83H antisense RNA 1 (head to head)
chr4_-_152149033 0.08 ENST00000514152.1
 SH3D19
 SH3 domain containing 19
chr2_+_220144052 0.08 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr16_+_16429787 0.08 ENST00000331436.4
ENST00000541593.1
 AC138969.4
 Protein PKD1P1
chrX_+_135251783 0.08 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr3_+_185304059 0.08 ENST00000427465.2
 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
chrX_-_131623874 0.08 ENST00000436215.1
 MBNL3
 muscleblind-like splicing regulator 3
chr6_-_166796461 0.08 ENST00000360961.6
ENST00000341756.6
 MPC1
 mitochondrial pyruvate carrier 1
chr22_+_23487513 0.08 ENST00000263116.2
ENST00000341989.4
 RAB36
 RAB36, member RAS oncogene family
chr19_-_58951496 0.08 ENST00000254166.3
 ZNF132
 zinc finger protein 132
chr11_+_6411636 0.08 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
 SMPD1
 sphingomyelin phosphodiesterase 1, acid lysosomal
chr12_+_4671352 0.08 ENST00000542744.1
 DYRK4
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr11_-_66103932 0.08 ENST00000311320.4
 RIN1
 Ras and Rab interactor 1
chr8_-_101118185 0.08 ENST00000523437.1
 RGS22
 regulator of G-protein signaling 22
chr1_-_45140074 0.08 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
 TMEM53
 transmembrane protein 53
chr3_-_10149907 0.08 ENST00000450660.2
ENST00000524279.1
 FANCD2OS
 FANCD2 opposite strand
chr11_-_66103867 0.08 ENST00000424433.2
 RIN1
 Ras and Rab interactor 1
chr2_+_48667983 0.08 ENST00000449090.2
 PPP1R21
 protein phosphatase 1, regulatory subunit 21
chr7_+_156902674 0.07 ENST00000594086.1
 AC006967.1
 Protein LOC100996426
chr8_+_22428457 0.07 ENST00000517962.1
 SORBS3
 sorbin and SH3 domain containing 3
chr15_+_85923856 0.07 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
 AKAP13
 A kinase (PRKA) anchor protein 13
chr5_+_154237778 0.07 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr9_+_131218408 0.07 ENST00000351030.3
ENST00000604420.1
ENST00000535026.1
ENST00000448249.3
ENST00000393527.3
 ODF2
 outer dense fiber of sperm tails 2
chr12_-_88535747 0.07 ENST00000309041.7
 CEP290
 centrosomal protein 290kDa
chr17_+_72270429 0.07 ENST00000311014.6
 DNAI2
 dynein, axonemal, intermediate chain 2
chr20_+_30865429 0.07 ENST00000375712.3
 KIF3B
 kinesin family member 3B
chr12_+_111051832 0.07 ENST00000550703.2
ENST00000551590.1
 TCTN1
 tectonic family member 1
chr1_+_245133062 0.07 ENST00000366523.1
 EFCAB2
 EF-hand calcium binding domain 2
chr10_+_35416090 0.07 ENST00000354759.3
 CREM
 cAMP responsive element modulator
chr7_-_139477500 0.07 ENST00000406875.3
ENST00000428878.2
 HIPK2
 homeodomain interacting protein kinase 2
chr2_+_26624775 0.07 ENST00000288710.2
 DRC1
 dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr6_-_44923160 0.07 ENST00000371458.1
 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
chr12_+_53693466 0.07 ENST00000267103.5
ENST00000548632.1
 C12orf10
 chromosome 12 open reading frame 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.4 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.8 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.4 GO:0090521 regulation of embryonic cell shape(GO:0016476) septin cytoskeleton organization(GO:0032185) glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.2 GO:1905154 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0006756 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0071878 negative regulation of adrenergic receptor signaling pathway(GO:0071878)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0016235 inclusion body(GO:0016234) aggresome(GO:0016235)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.0 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins