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Epithelial-Mesenchymal Transition, human (Scheel, 2011): : averaged replicates

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Results for RREB1

Z-value: 0.70

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Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
RREB1
ENSG00000124782.15 RREB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg19_v2_chr6_+_7107999_71080540.714.8e-02Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_35609380 1.23 ENST00000604621.1
 FXYD3
 FXYD domain containing ion transport regulator 3
chr19_-_51456321 1.16 ENST00000391809.2
 KLK5
 kallikrein-related peptidase 5
chr19_-_51456344 1.16 ENST00000336334.3
ENST00000593428.1
 KLK5
 kallikrein-related peptidase 5
chr19_-_51456198 1.03 ENST00000594846.1
 KLK5
 kallikrein-related peptidase 5
chr16_+_68771128 0.88 ENST00000261769.5
ENST00000422392.2
 CDH1
 cadherin 1, type 1, E-cadherin (epithelial)
chr19_-_6720686 0.82 ENST00000245907.6
 C3
 complement component 3
chr20_+_58179582 0.75 ENST00000371015.1
ENST00000395639.4
 PHACTR3
 phosphatase and actin regulator 3
chr14_-_105635090 0.72 ENST00000331782.3
ENST00000347004.2
 JAG2
 jagged 2
chr17_-_39677971 0.68 ENST00000393976.2
 KRT15
 keratin 15
chr6_-_136847610 0.64 ENST00000454590.1
ENST00000432797.2
 MAP7
 microtubule-associated protein 7
chr17_+_54671047 0.54 ENST00000332822.4
 NOG
 noggin
chr8_-_75233563 0.49 ENST00000342232.4
 JPH1
 junctophilin 1
chr1_-_153363452 0.49 ENST00000368732.1
ENST00000368733.3
 S100A8
 S100 calcium binding protein A8
chr8_-_142011036 0.46 ENST00000520892.1
 PTK2
 protein tyrosine kinase 2
chrX_+_102585124 0.43 ENST00000332431.4
ENST00000372666.1
 TCEAL7
 transcription elongation factor A (SII)-like 7
chr18_+_33877654 0.41 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
 FHOD3
 formin homology 2 domain containing 3
chr4_-_87374283 0.36 ENST00000361569.2
 MAPK10
 mitogen-activated protein kinase 10
chr8_+_32405785 0.36 ENST00000287842.3
 NRG1
 neuregulin 1
chr2_+_223289208 0.36 ENST00000321276.7
 SGPP2
 sphingosine-1-phosphate phosphatase 2
chr6_+_7541845 0.35 ENST00000418664.2
 DSP
 desmoplakin
chr6_+_7541808 0.34 ENST00000379802.3
 DSP
 desmoplakin
chr8_-_22550815 0.32 ENST00000317216.2
 EGR3
 early growth response 3
chr2_+_106468204 0.29 ENST00000425756.1
ENST00000393349.2
 NCK2
 NCK adaptor protein 2
chr12_+_54447637 0.29 ENST00000609810.1
ENST00000430889.2
 HOXC4
HOXC4
 homeobox C4
Homeobox protein Hox-C4
chr8_-_66754172 0.29 ENST00000401827.3
 PDE7A
 phosphodiesterase 7A
chr6_+_112375275 0.28 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
 WISP3
 WNT1 inducible signaling pathway protein 3
chr19_+_34287751 0.26 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
 KCTD15
 potassium channel tetramerization domain containing 15
chr6_-_13486369 0.25 ENST00000558378.1
 AL583828.1
 AL583828.1
chr17_+_7788104 0.25 ENST00000380358.4
 CHD3
 chromodomain helicase DNA binding protein 3
chr8_-_144655141 0.24 ENST00000398882.3
 MROH6
 maestro heat-like repeat family member 6
chr8_+_32406179 0.23 ENST00000405005.3
 NRG1
 neuregulin 1
chr12_-_12715266 0.23 ENST00000228862.2
 DUSP16
 dual specificity phosphatase 16
chr1_+_212782012 0.22 ENST00000341491.4
ENST00000366985.1
 ATF3
 activating transcription factor 3
chr2_+_234104079 0.22 ENST00000417661.1
 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
chr22_+_32750872 0.21 ENST00000397468.1
 RFPL3
 ret finger protein-like 3
chr19_-_42759300 0.19 ENST00000222329.4
 ERF
 Ets2 repressor factor
chr8_+_32406137 0.19 ENST00000521670.1
 NRG1
 neuregulin 1
chrX_-_151903101 0.19 ENST00000393900.3
 MAGEA12
 melanoma antigen family A, 12
chr4_+_74735102 0.19 ENST00000395761.3
 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chrX_-_151903184 0.19 ENST00000357916.4
ENST00000393869.3
 MAGEA12
 melanoma antigen family A, 12
chr3_-_116163830 0.18 ENST00000333617.4
 LSAMP
 limbic system-associated membrane protein
chr12_-_95044309 0.18 ENST00000261226.4
 TMCC3
 transmembrane and coiled-coil domain family 3
chr19_-_51471362 0.18 ENST00000376853.4
ENST00000424910.2
 KLK6
 kallikrein-related peptidase 6
chr19_+_44085189 0.18 ENST00000562365.2
 PINLYP
 phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr19_-_51471381 0.17 ENST00000594641.1
 KLK6
 kallikrein-related peptidase 6
chr17_-_6459802 0.17 ENST00000262483.8
 PITPNM3
 PITPNM family member 3
chr17_-_6459768 0.17 ENST00000421306.3
 PITPNM3
 PITPNM family member 3
chr19_-_44306590 0.17 ENST00000377950.3
 LYPD5
 LY6/PLAUR domain containing 5
chr6_+_112375462 0.16 ENST00000361714.1
 WISP3
 WNT1 inducible signaling pathway protein 3
chr19_+_48867652 0.16 ENST00000344846.2
 SYNGR4
 synaptogyrin 4
chr12_+_26348246 0.16 ENST00000422622.2
 SSPN
 sarcospan
chr12_+_26348429 0.16 ENST00000242729.2
 SSPN
 sarcospan
chr7_-_24797032 0.16 ENST00000409970.1
ENST00000409775.3
 DFNA5
 deafness, autosomal dominant 5
chrX_+_151081351 0.16 ENST00000276344.2
 MAGEA4
 melanoma antigen family A, 4
chr17_-_39728303 0.15 ENST00000588431.1
ENST00000246662.4
 KRT9
 keratin 9
chr13_-_76056250 0.15 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
 TBC1D4
 TBC1 domain family, member 4
chr17_+_1958388 0.15 ENST00000399849.3
 HIC1
 hypermethylated in cancer 1
chr2_-_46769694 0.15 ENST00000522587.1
 ATP6V1E2
 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr16_+_27325202 0.15 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
 IL4R
 interleukin 4 receptor
chr12_-_123849374 0.15 ENST00000602398.1
ENST00000602750.1
 SBNO1
 strawberry notch homolog 1 (Drosophila)
chr7_+_39125365 0.15 ENST00000559001.1
ENST00000464276.2
 POU6F2
 POU class 6 homeobox 2
chr3_-_48471454 0.14 ENST00000296440.6
ENST00000448774.2
 PLXNB1
 plexin B1
chr12_-_71314617 0.14 ENST00000283228.2
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr4_-_100485143 0.14 ENST00000394877.3
 TRMT10A
 tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr7_-_102257139 0.14 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
 RASA4
 RAS p21 protein activator 4
chr1_+_18958008 0.14 ENST00000420770.2
ENST00000400661.3
 PAX7
 paired box 7
chr1_-_155947951 0.14 ENST00000313695.7
ENST00000497907.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr11_+_128562372 0.13 ENST00000344954.6
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr21_+_44073916 0.13 ENST00000349112.3
ENST00000398224.3
 PDE9A
 phosphodiesterase 9A
chr7_-_51384451 0.13 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
 COBL
 cordon-bleu WH2 repeat protein
chr13_-_99852916 0.13 ENST00000426037.2
ENST00000445737.2
 UBAC2-AS1
 UBAC2 antisense RNA 1
chr20_-_36793663 0.12 ENST00000536701.1
ENST00000536724.1
 TGM2
 transglutaminase 2
chr21_+_44073860 0.12 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
 PDE9A
 phosphodiesterase 9A
chr7_-_71801980 0.12 ENST00000329008.5
 CALN1
 calneuron 1
chr9_+_84304628 0.12 ENST00000437181.1
 RP11-154D17.1
 RP11-154D17.1
chr17_+_35849937 0.12 ENST00000394389.4
 DUSP14
 dual specificity phosphatase 14
chr4_-_100484825 0.12 ENST00000273962.3
ENST00000514547.1
ENST00000455368.2
 TRMT10A
 tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr19_+_44084696 0.12 ENST00000562255.1
ENST00000569031.2
 PINLYP
 phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr17_-_66597530 0.12 ENST00000592554.1
 FAM20A
 family with sequence similarity 20, member A
chr7_-_752074 0.12 ENST00000360274.4
 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
chr17_-_43502987 0.11 ENST00000376922.2
 ARHGAP27
 Rho GTPase activating protein 27
chr10_-_121356518 0.11 ENST00000369092.4
 TIAL1
 TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr6_-_31560729 0.11 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
 NCR3
 natural cytotoxicity triggering receptor 3
chr12_+_54943134 0.11 ENST00000243052.3
 PDE1B
 phosphodiesterase 1B, calmodulin-dependent
chr19_-_49140609 0.10 ENST00000601104.1
 DBP
 D site of albumin promoter (albumin D-box) binding protein
chr2_+_171571827 0.10 ENST00000375281.3
 SP5
 Sp5 transcription factor
chr11_+_46402744 0.10 ENST00000533952.1
 MDK
 midkine (neurite growth-promoting factor 2)
chr11_+_2323236 0.10 ENST00000182290.4
 TSPAN32
 tetraspanin 32
chr17_+_80376194 0.10 ENST00000337014.6
 HEXDC
 hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr5_+_175299743 0.10 ENST00000502265.1
 CPLX2
 complexin 2
chr19_+_6135646 0.10 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
 ACSBG2
 acyl-CoA synthetase bubblegum family member 2
chr9_+_132427883 0.10 ENST00000372469.4
 PRRX2
 paired related homeobox 2
chr2_+_85661918 0.10 ENST00000340326.2
 SH2D6
 SH2 domain containing 6
chr11_-_75062829 0.10 ENST00000393505.4
 ARRB1
 arrestin, beta 1
chr1_-_156470556 0.09 ENST00000489057.1
ENST00000348159.4
 MEF2D
 myocyte enhancer factor 2D
chr19_+_41305330 0.09 ENST00000593972.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr8_-_145331153 0.09 ENST00000377412.4
 KM-PA-2
 KM-PA-2 protein; Uncharacterized protein
chr17_-_41132088 0.09 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
 PTGES3L
PTGES3L-AARSD1
 prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr3_+_57094469 0.09 ENST00000334325.1
 SPATA12
 spermatogenesis associated 12
chr11_+_66886717 0.09 ENST00000398645.2
 KDM2A
 lysine (K)-specific demethylase 2A
chr19_-_39226045 0.09 ENST00000597987.1
ENST00000595177.1
 CAPN12
 calpain 12
chr10_+_127661942 0.09 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
 FANK1
 fibronectin type III and ankyrin repeat domains 1
chr11_-_57089671 0.09 ENST00000532437.1
 TNKS1BP1
 tankyrase 1 binding protein 1, 182kDa
chr1_-_153538292 0.08 ENST00000497140.1
ENST00000368708.3
 S100A2
 S100 calcium binding protein A2
chr11_-_75062730 0.08 ENST00000420843.2
ENST00000360025.3
 ARRB1
 arrestin, beta 1
chr1_-_156470515 0.08 ENST00000340875.5
ENST00000368240.2
ENST00000353795.3
 MEF2D
 myocyte enhancer factor 2D
chr4_-_38666430 0.08 ENST00000436901.1
 AC021860.1
 Uncharacterized protein
chr18_-_3874271 0.08 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
chr2_-_136873735 0.08 ENST00000409817.1
 CXCR4
 chemokine (C-X-C motif) receptor 4
chr18_-_21242774 0.08 ENST00000322980.9
 ANKRD29
 ankyrin repeat domain 29
chr12_+_132413739 0.08 ENST00000443358.2
 PUS1
 pseudouridylate synthase 1
chr19_-_33555780 0.08 ENST00000254260.3
ENST00000400226.4
 RHPN2
 rhophilin, Rho GTPase binding protein 2
chr10_-_103603568 0.08 ENST00000356640.2
 KCNIP2
 Kv channel interacting protein 2
chr12_-_57522813 0.08 ENST00000556155.1
 STAT6
 signal transducer and activator of transcription 6, interleukin-4 induced
chr2_-_32236002 0.08 ENST00000404530.1
 MEMO1
 mediator of cell motility 1
chr17_-_39216344 0.07 ENST00000391418.2
 KRTAP2-3
 keratin associated protein 2-3
chr14_+_23563952 0.07 ENST00000319074.4
 C14orf119
 chromosome 14 open reading frame 119
chr5_+_78908388 0.07 ENST00000296783.3
 PAPD4
 PAP associated domain containing 4
chr12_+_26348582 0.07 ENST00000535504.1
 SSPN
 sarcospan
chr16_+_30935418 0.07 ENST00000338343.4
 FBXL19
 F-box and leucine-rich repeat protein 19
chr19_+_2164126 0.07 ENST00000398665.3
 DOT1L
 DOT1-like histone H3K79 methyltransferase
chr19_-_19051927 0.07 ENST00000600077.1
 HOMER3
 homer homolog 3 (Drosophila)
chr1_-_204380919 0.07 ENST00000367188.4
 PPP1R15B
 protein phosphatase 1, regulatory subunit 15B
chr17_+_58499066 0.07 ENST00000474834.1
 C17orf64
 chromosome 17 open reading frame 64
chr8_+_145064233 0.07 ENST00000529301.1
ENST00000395068.4
 GRINA
 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr10_-_126849068 0.07 ENST00000494626.2
ENST00000337195.5
 CTBP2
 C-terminal binding protein 2
chr6_+_29407083 0.07 ENST00000444197.2
 OR10C1
 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr15_+_77712993 0.07 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
 HMG20A
 high mobility group 20A
chr19_+_41305612 0.07 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr19_+_41305627 0.06 ENST00000593525.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr2_+_228337079 0.06 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
 AGFG1
 ArfGAP with FG repeats 1
chr17_-_73840415 0.06 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
 UNC13D
 unc-13 homolog D (C. elegans)
chr17_+_6918354 0.06 ENST00000552775.1
 C17orf49
 chromosome 17 open reading frame 49
chr10_-_112064665 0.06 ENST00000369603.5
 SMNDC1
 survival motor neuron domain containing 1
chr11_+_46403303 0.06 ENST00000407067.1
ENST00000395565.1
 MDK
 midkine (neurite growth-promoting factor 2)
chrX_+_37545012 0.06 ENST00000378616.3
 XK
 X-linked Kx blood group (McLeod syndrome)
chr5_-_35195338 0.06 ENST00000509839.1
 PRLR
 prolactin receptor
chr22_-_37976082 0.06 ENST00000215886.4
 LGALS2
 lectin, galactoside-binding, soluble, 2
chr15_-_43513187 0.06 ENST00000540029.1
ENST00000441366.2
 EPB42
 erythrocyte membrane protein band 4.2
chr6_-_35480705 0.06 ENST00000229771.6
 TULP1
 tubby like protein 1
chr8_-_66753682 0.06 ENST00000396642.3
 PDE7A
 phosphodiesterase 7A
chr12_+_132413798 0.06 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
 PUS1
 pseudouridylate synthase 1
chr17_+_58499844 0.06 ENST00000269127.4
 C17orf64
 chromosome 17 open reading frame 64
chr5_+_78908233 0.06 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
 PAPD4
 PAP associated domain containing 4
chr19_+_41305085 0.06 ENST00000303961.4
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr19_-_51336443 0.06 ENST00000598673.1
 KLK15
 kallikrein-related peptidase 15
chrX_-_48693955 0.06 ENST00000218230.5
 PCSK1N
 proprotein convertase subtilisin/kexin type 1 inhibitor
chr19_-_19051993 0.06 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
 HOMER3
 homer homolog 3 (Drosophila)
chr3_-_52869205 0.05 ENST00000446157.2
 MUSTN1
 musculoskeletal, embryonic nuclear protein 1
chr11_+_46403194 0.05 ENST00000395569.4
ENST00000395566.4
 MDK
 midkine (neurite growth-promoting factor 2)
chr6_-_35480640 0.05 ENST00000428978.1
ENST00000322263.4
 TULP1
 tubby like protein 1
chr17_-_77005860 0.05 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
 CANT1
 calcium activated nucleotidase 1
chr11_+_66406088 0.05 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
 RBM4
 RNA binding motif protein 4
chr12_+_132413765 0.05 ENST00000376649.3
ENST00000322060.5
 PUS1
 pseudouridylate synthase 1
chr2_+_192543153 0.05 ENST00000425611.2
 NABP1
 nucleic acid binding protein 1
chr10_-_103603523 0.05 ENST00000370046.1
 KCNIP2
 Kv channel interacting protein 2
chr11_-_129872712 0.05 ENST00000358825.5
ENST00000360871.3
ENST00000528746.1
 PRDM10
 PR domain containing 10
chr13_-_52027134 0.05 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6
 integrator complex subunit 6
chr19_+_41305740 0.05 ENST00000596517.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr4_+_164265035 0.05 ENST00000338566.3
 NPY5R
 neuropeptide Y receptor Y5
chr19_+_13056663 0.05 ENST00000541222.1
ENST00000316856.3
ENST00000586534.1
ENST00000592268.1
 RAD23A
 RAD23 homolog A (S. cerevisiae)
chr10_+_134145735 0.05 ENST00000368613.4
 LRRC27
 leucine rich repeat containing 27
chr3_-_55521323 0.05 ENST00000264634.4
 WNT5A
 wingless-type MMTV integration site family, member 5A
chr12_+_57916584 0.05 ENST00000546632.1
ENST00000549623.1
ENST00000431731.2
 MBD6
 methyl-CpG binding domain protein 6
chr3_+_8775466 0.05 ENST00000343849.2
ENST00000397368.2
 CAV3
 caveolin 3
chrX_-_148571884 0.05 ENST00000537071.1
 IDS
 iduronate 2-sulfatase
chrX_+_151867214 0.05 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
 MAGEA6
 melanoma antigen family A, 6
chr10_+_52751010 0.05 ENST00000373985.1
 PRKG1
 protein kinase, cGMP-dependent, type I
chr2_-_74570520 0.05 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
 SLC4A5
 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr6_+_33387830 0.05 ENST00000293748.5
 SYNGAP1
 synaptic Ras GTPase activating protein 1
chr6_+_33388013 0.05 ENST00000449372.2
 SYNGAP1
 synaptic Ras GTPase activating protein 1
chr13_+_24734880 0.05 ENST00000382095.4
 SPATA13
 spermatogenesis associated 13
chr18_-_3874247 0.05 ENST00000581699.1
 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
chr1_+_220267429 0.05 ENST00000366922.1
ENST00000302637.5
 IARS2
 isoleucyl-tRNA synthetase 2, mitochondrial
chr19_-_18654293 0.05 ENST00000597547.1
ENST00000222308.4
ENST00000544835.3
ENST00000610101.1
ENST00000597960.3
ENST00000608443.1
 FKBP8
 FK506 binding protein 8, 38kDa
chr7_-_128045984 0.05 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
 IMPDH1
 IMP (inosine 5'-monophosphate) dehydrogenase 1
chr15_+_21145765 0.05 ENST00000553416.1
 CT60
 cancer/testis antigen 60 (non-protein coding)
chr1_-_31712401 0.05 ENST00000373736.2
 NKAIN1
 Na+/K+ transporting ATPase interacting 1
chr12_-_8088871 0.05 ENST00000075120.7
 SLC2A3
 solute carrier family 2 (facilitated glucose transporter), member 3
chr5_+_76145920 0.05 ENST00000317593.4
 S100Z
 S100 calcium binding protein Z
chrX_-_8769378 0.05 ENST00000543214.1
ENST00000381003.3
 FAM9A
 family with sequence similarity 9, member A
chr15_-_70390191 0.05 ENST00000559191.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr18_-_3874752 0.05 ENST00000534970.1
 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
chr5_+_76145826 0.05 ENST00000513010.1
 S100Z
 S100 calcium binding protein Z
chr12_+_62654155 0.05 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
 USP15
 ubiquitin specific peptidase 15
chr9_+_96026230 0.05 ENST00000448251.1
 WNK2
 WNK lysine deficient protein kinase 2
chr12_-_16759711 0.05 ENST00000447609.1
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr13_+_28813645 0.05 ENST00000282391.5
 PAN3
 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_+_149737046 0.04 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
 MTM1
 myotubularin 1
chr12_+_57916466 0.04 ENST00000355673.3
 MBD6
 methyl-CpG binding domain protein 6
chr19_+_7828035 0.04 ENST00000327325.5
ENST00000394122.2
ENST00000248228.4
ENST00000334806.5
ENST00000359059.5
ENST00000357361.2
ENST00000596363.1
ENST00000595751.1
ENST00000596707.1
ENST00000597522.1
ENST00000595496.1
 CLEC4M
 C-type lectin domain family 4, member M
chr9_-_34126730 0.04 ENST00000361264.4
 DCAF12
 DDB1 and CUL4 associated factor 12
chr17_+_18761417 0.04 ENST00000419284.2
ENST00000268835.2
ENST00000412418.1
ENST00000575228.1
ENST00000575102.1
ENST00000536323.1
 PRPSAP2
 phosphoribosyl pyrophosphate synthetase-associated protein 2
chr8_-_114389353 0.04 ENST00000343508.3
 CSMD3
 CUB and Sushi multiple domains 3
chr9_-_21994344 0.04 ENST00000530628.2
ENST00000361570.3
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr19_+_41305406 0.04 ENST00000406058.2
ENST00000593726.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr17_-_46703826 0.04 ENST00000550387.1
ENST00000311177.5
 HOXB9
 homeobox B9
chr9_-_21994597 0.04 ENST00000579755.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr22_-_51066521 0.04 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
 ARSA
 arylsulfatase A
chr5_-_142065223 0.04 ENST00000378046.1
 FGF1
 fibroblast growth factor 1 (acidic)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 0.8 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 1.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.9 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 1.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.3 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.5 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.4 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0090240 follicle-stimulating hormone signaling pathway(GO:0042699) positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0061346 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.5 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 4.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.6 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha